Development Level

Tbio 15 | 11,651

IMPC Phenotype

decreased circulating insulin ... 2 | 76
decreased vertical activity 2 | 208
enlarged heart 2 | 210
preweaning lethality, complete... 2 | 979
abnormal coat-hair pigmentatio... 1 | 64
abnormal eye morphology 1 | 68
abnormal heart morphology 1 | 162
abnormal humerus morphology 1 | 11
abnormal incisor color 1 | 3
abnormal lens morphology 1 | 81
abnormal liver morphology 1 | 17
abnormal lung morphology 1 | 26
abnormal seminal vesicle morph... 1 | 114
abnormal thoracic cage shape 1 | 3
abnormal tibia morphology 1 | 14
abnormal tooth morphology 1 | 24
cataract 1 | 92
decreased body length 1 | 101
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating phosphat... 1 | 27
decreased heart weight 1 | 27
decreased lean body mass 1 | 135
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular hem... 1 | 31
increased bone mineral content 1 | 108
increased heart weight 1 | 62
increased mean corpuscular hem... 1 | 96

Disease

Carcinoma 11 | 11,493
ovarian cancer 10 | 8,520
lung cancer 9 | 4,740
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,955
medulloblastoma, large-cell 7 | 6,241
pancreatic cancer 7 | 2,398
psoriasis 7 | 6,694
Autosomal recessive predisposition 6 | 1,442
Cancer 6 | 2,499
lung adenocarcinoma 6 | 2,716
non-small cell lung cancer 6 | 2,890
osteosarcoma 6 | 7,950
Astrocytoma, Pilocytic 5 | 3,081
Atherosclerosis 5 | 291
Breast cancer 5 | 3,578
Kidney cancer 5 | 2,613
cystic fibrosis 5 | 1,696
glioblastoma 5 | 5,792
interstitial cystitis 5 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
lung carcinoma 5 | 2,843
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
Congenital afibrinogenemia 4 | 11
Epistaxis 4 | 43
Gastrointestinal Hemorrhage 4 | 52
Osteoporosis 4 | 363
Schizophrenia 4 | 1,160
adult high grade glioma 4 | 3,801
atypical teratoid / rhabdoid tumor 4 | 5,112
diabetes mellitus 4 | 1,728
ependymoma 4 | 4,679
gastric carcinoma 4 | 807
group 3 medulloblastoma 4 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
invasive ductal carcinoma 4 | 2,951
ulcerative colitis 4 | 1,819
Afibrinogenemia 3 | 4
Afibrinogenemia, congenital 3 | 3
Bleeding tendency 3 | 37
Cerebrovascular disease 3 | 238
Cholestasis 3 | 155
Congenital hypofibrinogenemia 3 | 3
Coronary artery disease 3 | 268
Disseminated intravascular coagulation 3 | 38
Dysfibrinogenemia, Congenital 3 | 3
Familial dysfibrinogenemia 3 | 3
Familial hypofibrinogenemia 3 | 3
Gingival Hemorrhage 3 | 18
Hypertensive disease 3 | 292
Hypofibrinogenemia 3 | 4
Intermenstrual heavy bleeding 3 | 4
Joint swelling 3 | 26
Kidney Diseases 3 | 114
Kidney disease 3 | 430
Muscle hypotonia 3 | 571
Spontaneous abortion 3 | 113
Thrombocytopenia 3 | 197
Thrombophilia 3 | 38
Venous Thrombosis 3 | 47
adrenocortical carcinoma 3 | 1,428
colon cancer 3 | 1,478
ductal carcinoma in situ 3 | 1,745
esophageal adenocarcinoma 3 | 737
gastric cancer 3 | 459
malignant mesothelioma 3 | 3,232
mucosa-associated lymphoid tissue lymphoma 3 | 484
nasopharyngeal carcinoma 3 | 1,058
pancreatic carcinoma 3 | 562
primary pancreatic ductal adenocarcinoma 3 | 1,109
Arthritis, Juvenile 2 | 126
Atopic dermatitis 2 | 952
Diabetic Angiopathies 2 | 16
Down syndrome 2 | 499
Duchenne muscular dystrophy 2 | 601
Heart disease 2 | 306
Highly variable severity 2 | 157
Hypertension 2 | 396
Juvenile arthritis 2 | 126
Liver Cirrhosis 2 | 181
Liver Cirrhosis, Experimental 2 | 769
Mental and motor retardation 2 | 608
Multiple myeloma 2 | 1,332
Peripheral vascular disease 2 | 87
Pick disease 2 | 1,894
Pulmonary embolism 2 | 55
Variable expressivity 2 | 157
Vascular disease 2 | 319
active Crohn's disease 2 | 922
active ulcerative colitis 2 | 764
acute myeloid leukemia 2 | 783
astrocytic glioma 2 | 2,597
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
cutaneous lupus erythematosus 2 | 1,057
hepatocellular carcinoma 2 | 547
oligodendroglioma 2 | 2,850
pituitary cancer 2 | 1,972
primitive neuroectodermal tumor 2 | 3,035
pterygium 2 | 76
subependymal giant cell astrocytoma 2 | 2,287
urothelial carcinoma 2 | 318

Tissue

Blood and immune system 15 | 16,909
Digestive Tract 15 | 17,369
Endocrine System 15 | 18,159
Female tissues 15 | 17,400
Liver and Pancreas 15 | 16,750
Male tissues 15 | 17,142
Respiratory system 15 | 16,393
Skin and soft tissues 15 | 17,230
Urinary Tract 15 | 16,678
Cardiovascular System 14 | 15,192
Nervous System 13 | 16,725

Target Family

Non-IDG 14 | 12,091
Enzyme 1 | 4,145

GO Component

platelet alpha granule 15 | 15
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Thrombospondin-1 THBS1 Tbio Non-IDG -3.06622 1281.6 504
Vesicle-associated membrane protein 7 VAMP7 Tbio Non-IDG -1.87033 83.5 146
Fibrinogen beta chain FGB Tbio Non-IDG -2.09043 116.8 352
SPARC SPARC Tbio Non-IDG -3.10194 1136.1 543
Syntaxin-binding protein 1 STXBP1 Tbio Non-IDG -2.30714 221.0 351
Thrombospondin-2 THBS2 Tbio Non-IDG -2.35608 237.7 150
Glia-derived nexin SERPINE2 Tbio Non-IDG -2.56699 376.5 215
Syntaxin-binding protein 3 STXBP3 Tbio Non-IDG -1.41720 31.3 146
Vacuolar protein sorting-associated protein 33B VPS33B Tbio Non-IDG -1.54312 36.3 34
Fibrinogen alpha chain FGA Tbio Non-IDG -2.88066 753.1 595