Development Level

Tbio 2,590 | 11,651
Tdark 917 | 6,593
Tchem 524 | 1,388
Tclin 383 | 612

Collection

GPCR: IDG Consortium (Targets) 95 | 126
Ion Channel: IDG Consortium (T... 69 | 99
GPCR: IDG Consortium (Complete... 21 | 25
Kinase: IDG Consortium (Target... 20 | 125
Kinase: IDG Consortium (Comple... 5 | 37

IMPC Phenotype

preweaning lethality, complete... 188 | 979
preweaning lethality, incomple... 127 | 499
abnormal behavior 85 | 298
embryonic lethality prior to t... 65 | 278
decreased vertical activity 58 | 208
decreased total body fat amoun... 54 | 207
abnormal embryo size 51 | 220
abnormal bone structure 48 | 187
hyperactivity 47 | 148
embryonic lethality prior to o... 46 | 239
enlarged heart 46 | 210
increased total body fat amoun... 46 | 134
decreased bone mineral content 45 | 151
increased lean body mass 42 | 172
decreased body weight 41 | 161
abnormal seminal vesicle morph... 36 | 114
decreased lean body mass 35 | 135
decreased bone mineral density 34 | 126
increased circulating alkaline... 34 | 122
abnormal heart morphology 32 | 162
increased startle reflex 32 | 112
hypoactivity 30 | 132
decreased circulating glucose ... 27 | 126
improved glucose tolerance 26 | 79
impaired glucose tolerance 25 | 75
increased bone mineral content 25 | 108
decreased body length 24 | 101
decreased grip strength 24 | 116
decreased lymphocyte cell numb... 24 | 83
short tibia 24 | 97
decreased fasted circulating g... 23 | 65
decreased mean corpuscular vol... 23 | 79
embryonic growth retardation 23 | 106
abnormal sleep behavior 22 | 70
increased or absent threshold ... 22 | 101
decreased leukocyte cell numbe... 21 | 73
small superior vagus ganglion 21 | 74
abnormal eye morphology 20 | 68
abnormal gait 20 | 69
decreased prepulse inhibition 20 | 82
increased circulating chloride... 20 | 41
increased leukocyte cell numbe... 20 | 47
increased mean corpuscular vol... 20 | 92
cataract 19 | 92
increased circulating HDL chol... 19 | 80
increased fasted circulating g... 19 | 76
limb grasping 19 | 41
prenatal lethality prior to he... 19 | 87
decreased circulating choleste... 18 | 93
decreased startle reflex 18 | 75
increased circulating sodium l... 18 | 71
increased circulating triglyce... 18 | 42
thrombocytopenia 18 | 56
decreased circulating triglyce... 17 | 79
edema 17 | 59
increased monocyte cell number 17 | 63
decreased mean corpuscular hem... 16 | 50
increased bone mineral density 16 | 72
increased circulating choleste... 16 | 66
increased neutrophil cell numb... 16 | 46
increased heart weight 15 | 62
male infertility 15 | 123
tremors 15 | 39
abnormal kidney morphology 14 | 65
abnormal lens morphology 14 | 81
abnormal retina morphology 14 | 71
decreased circulating creatini... 14 | 39
decreased circulating insulin ... 14 | 76
decreased circulating serum al... 14 | 82
decreased hemoglobin content 14 | 68
abnormal epididymis morphology 13 | 42
abnormal testis morphology 13 | 43
cardiovascular system phenotyp... 13 | 36
increased blood urea nitrogen ... 13 | 48
increased hemoglobin content 13 | 45
increased mean corpuscular hem... 13 | 96
pallor 13 | 34
small testis 13 | 58
abnormal behavioral response t... 12 | 66
abnormal neural tube closure 12 | 46
abnormal skin morphology 12 | 50
abnormal spleen morphology 12 | 55
decreased circulating HDL chol... 12 | 68
decreased erythrocyte cell num... 12 | 62
hydrometra 12 | 53
increased hematocrit 12 | 46
prolonged QT interval 12 | 38
abnormal coat appearance 11 | 31
abnormal coat-hair pigmentatio... 11 | 64
decreased heart weight 11 | 27
decreased neutrophil cell numb... 11 | 42
enlarged epididymis 11 | 31
increased body length 11 | 32
increased circulating calcium ... 11 | 34
increased circulating creatini... 11 | 38
increased mean platelet volume 11 | 45
pale yolk sac 11 | 25
prolonged ST segment 11 | 36
abnormal locomotor behavior 10 | 24
increased erythrocyte cell num... 10 | 39

Disease

Carcinoma 2,967 | 11,493
osteosarcoma 1,777 | 7,950
ovarian cancer 1,769 | 8,520
psoriasis 1,642 | 6,694
medulloblastoma, large-cell 1,503 | 6,241
glioblastoma 1,478 | 5,792
atypical teratoid / rhabdoid tumor 1,263 | 5,112
lung cancer 1,184 | 4,740
ependymoma 1,174 | 4,679
adult high grade glioma 1,036 | 3,801
lung carcinoma 974 | 2,843
Astrocytoma, Pilocytic 938 | 3,081
group 3 medulloblastoma 907 | 4,104
Breast cancer 856 | 3,578
Cancer 852 | 2,499
non-small cell lung cancer 813 | 2,890
invasive ductal carcinoma 804 | 2,951
lung adenocarcinoma 794 | 2,716
malignant mesothelioma 794 | 3,232
intraductal papillary-mucinous neoplasm (IPMN) 793 | 3,291
intraductal papillary-mucinous adenoma (IPMA) 777 | 2,955
Kidney cancer 774 | 2,613
interstitial cystitis 763 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 741 | 2,989
primitive neuroectodermal tumor 721 | 3,035
oligodendroglioma 717 | 2,850
pancreatic cancer 674 | 2,398
subependymal giant cell astrocytoma 640 | 2,287
astrocytic glioma 635 | 2,597
tuberculosis 591 | 2,010
ulcerative colitis 560 | 1,819
pituitary cancer 550 | 1,972
diabetes mellitus 547 | 1,728
ductal carcinoma in situ 493 | 1,745
cystic fibrosis 460 | 1,696
Pick disease 457 | 1,894
Schizophrenia 442 | 1,160
group 4 medulloblastoma 435 | 1,855
breast carcinoma 434 | 1,638
Autosomal recessive predisposition 405 | 1,442
pancreatic ductal adenocarcinoma liver metastasis 401 | 1,962
colon cancer 390 | 1,478
Rheumatoid arthritis 371 | 1,191
cutaneous lupus erythematosus 365 | 1,057
adrenocortical carcinoma 345 | 1,428
primary pancreatic ductal adenocarcinoma 314 | 1,109
astrocytoma 297 | 1,146
juvenile dermatomyositis 272 | 1,187
active Crohn's disease 264 | 922
Bipolar Disorder 257 | 666
dermatomyositis 255 | 966
pediatric high grade glioma 254 | 1,064
spina bifida 252 | 1,074
Melanoma 250 | 711
acute quadriplegic myopathy 246 | 1,158
active ulcerative colitis 243 | 764
gastric carcinoma 243 | 807
Epilepsy 241 | 792
Liver Cirrhosis, Experimental 241 | 769
nasopharyngeal carcinoma 240 | 1,058
Intellectual disability 239 | 1,016
Multiple myeloma 236 | 1,332
Multiple Sclerosis 235 | 540
Atopic dermatitis 228 | 952
primary Sjogren syndrome 227 | 735
esophageal adenocarcinoma 225 | 737
Alzheimer's disease 221 | 658
Obesity 221 | 678
Liver cancer 213 | 604
non primary Sjogren syndrome sicca 198 | 891
Duchenne muscular dystrophy 193 | 601
mucosa-associated lymphoid tissue lymphoma 190 | 484
Skin cancer 189 | 469
Hypertension 187 | 396
Kidney disease 186 | 430
Down syndrome 174 | 499
fibroadenoma 168 | 559
Depressive disorder 164 | 409
Hypersensitivity reaction type II disease 161 | 253
acute myeloid leukemia 159 | 783
aldosterone-producing adenoma 159 | 665
Seizures 157 | 596
Prostatic Neoplasms 154 | 495
Asthma 153 | 385
Autistic Disorder 152 | 364
autosomal dominant Emery-Dreifuss muscular dystrophy 151 | 510
Dull intelligence 149 | 645
Low intelligence 149 | 645
Mental Retardation 149 | 645
Mental deficiency 149 | 645
Poor school performance 149 | 645
Alcoholic Intoxication, Chronic 148 | 289
Arthritis 148 | 290
Parkinson's disease 148 | 392
pancreatic carcinoma 146 | 562
Waldenstrons macroglobulinemia 145 | 765
medulloblastoma 144 | 720
Mental Depression 142 | 333
progressive supranuclear palsy 137 | 676
Breast Neoplasms 136 | 445

Tissue

Endocrine System 3,724 | 18,159
Digestive Tract 3,561 | 17,369
Female tissues 3,554 | 17,400
Skin and soft tissues 3,499 | 17,230
Male tissues 3,495 | 17,142
Blood and immune system 3,452 | 16,909
Nervous System 3,448 | 16,725
Urinary Tract 3,426 | 16,678
Liver and Pancreas 3,419 | 16,750
Respiratory system 3,332 | 16,393
Cardiovascular System 3,030 | 15,192

Target Family

Non-IDG 2,198 | 12,091
Enzyme 646 | 4,145
oGPCR 419 | 421
GPCR 355 | 408
Transporter 283 | 473
Ion Channel 280 | 344
Kinase 186 | 634
Transcription Factor 28 | 1,400
Epigenetic 14 | 242
TF/Epigenetic 3 | 38
Nuclear Receptor 2 | 48

GO Component

plasma membrane 4,414 | 4,414
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Paralemmin-3 PALM3 Tbio Non-IDG -0.66901 5.71 76
Epithelial membrane protein 2 EMP2 Tbio Non-IDG -2.30856 210.6 116
Ras-related protein Rab-22A RAB22A Tbio Enzyme -1.40824 19.7 123
Olfactory receptor 5H15 OR5H15 Tdark oGPCR 0.00000 35
43 kDa receptor-associated protein of the synapse RAPSN Tbio Non-IDG -2.09902 132.1 134
Olfactory receptor 7D2 OR7D2 Tdark oGPCR 0.00000 2
Integrin alpha-11 ITGA11 Tbio Non-IDG -1.13736 14.3 76
Annexin A13 ANXA13 Tbio Non-IDG -1.19458 15.6 162
Endothelin-converting enzyme 1 ECE1 Tchem Enzyme -2.56360 355.0 278
Sodium/potassium-transporting ATPase subunit alpha-4 ATP1A4 Tclin Transporter -1.73566 51.3 5