Development Level

Tbio 35 | 11,445
Tchem 3 | 1,598

IMPC Phenotype

increased lean body mass 3 | 172
absent pinna reflex 2 | 23
decreased total body fat amoun... 2 | 207
embryonic lethality prior to t... 2 | 278
impaired righting response 2 | 26
increased circulating sodium l... 2 | 71
increased or absent threshold ... 2 | 101
limb grasping 2 | 41
preweaning lethality, incomple... 2 | 499
stereotypic behavior 2 | 3
trunk curl 2 | 16
abnormal behavior 1 | 298
abnormal behavioral response t... 1 | 66
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal coat-hair pigmentatio... 1 | 64
abnormal ear morphology 1 | 9
abnormal locomotor activation 1 | 16
absent startle reflex 1 | 24
decreased body weight 1 | 161
decreased circulating amylase ... 1 | 28
decreased circulating calcium ... 1 | 36
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased circulating potassiu... 1 | 20
decreased circulating triglyce... 1 | 79
decreased grip strength 1 | 116
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular vol... 1 | 79
decreased prepulse inhibition 1 | 82
decreased startle reflex 1 | 75
decreased vertical activity 1 | 208
embryonic lethality prior to o... 1 | 239
improved glucose tolerance 1 | 79
increased blood urea nitrogen ... 1 | 48
increased bone mineral content 1 | 108
increased circulating HDL chol... 1 | 80
increased circulating chloride... 1 | 41
increased circulating choleste... 1 | 66
increased heart rate 1 | 23
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
increased thermal nociceptive ... 1 | 9
increased total body fat amoun... 1 | 134
persistence of hyaloid vascula... 1 | 33
polycystic kidney 1 | 15
prenatal lethality prior to he... 1 | 87
preweaning lethality, complete... 1 | 979
shortened RR interval 1 | 17
tremors 1 | 39

Disease

Carcinoma 25 | 11,493
Retinitis Pigmentosa 20 | 226
osteosarcoma 17 | 7,950
Intellectual disability 16 | 1,016
group 3 medulloblastoma 15 | 4,104
medulloblastoma, large-cell 15 | 6,241
Autosomal recessive predisposition 14 | 1,442
Electroretinogram abnormal 14 | 95
Difficulties with night vision 13 | 87
Dull intelligence 13 | 645
Low intelligence 13 | 645
Mental Retardation 13 | 645
Mental deficiency 13 | 645
Night Blindness 13 | 101
Poor school performance 13 | 645
Fundus dystrophy 12 | 83
Blindness 11 | 88
Cataract 11 | 297
Lens Opacities 11 | 231
Nystagmus 11 | 317
Photodysphoria 11 | 121
Photophobia 11 | 121
ependymoma 11 | 4,679
Abnormality of retinal pigmentation 10 | 111
Kidney cancer 10 | 2,613
Retinal pigment epithelial abnormality 10 | 111
Sensorineural Hearing Loss (disorder) 10 | 284
glioblastoma 10 | 5,792
lung carcinoma 10 | 2,843
ovarian cancer 10 | 8,520
Cone dystrophy 9 | 71
Congenital hypoplasia of penis 9 | 176
Obesity 9 | 678
adult high grade glioma 9 | 3,801
lung cancer 9 | 4,740
Hypogonadism 8 | 173
Keratoconus 8 | 113
Retinal Degeneration 8 | 106
cone-rod dystrophy 8 | 59
pituitary cancer 8 | 1,972
primitive neuroectodermal tumor 8 | 3,035
psoriasis 8 | 6,694
Abnormality of the retinal vasculature 7 | 59
Anteverted nostril 7 | 191
Atypical scarring of skin 7 | 62
Blind Vision 7 | 111
Blindness, Legal 7 | 110
Broad flat nasal bridge 7 | 236
Conductive hearing loss 7 | 123
Congenital anomaly of testis 7 | 52
Glaucoma 7 | 239
Hyperinsulinism 7 | 133
Low Vision 7 | 174
Nasal bridge wide 7 | 236
Night blindness, progressive 7 | 51
Ophthalmoplegia 7 | 106
Optic Atrophy 7 | 242
Schizophrenia 7 | 1,160
Visual Impairment 7 | 174
astrocytic glioma 7 | 2,597
atypical teratoid / rhabdoid tumor 7 | 5,112
malignant mesothelioma 7 | 3,232
Leber congenital amaurosis 6 | 69
Usher syndrome 6 | 32
Astrocytoma, Pilocytic 5 | 3,081
Cerebellar Ataxia 5 | 304
Cognitive delay 5 | 608
Global developmental delay 5 | 608
Mental and motor retardation 5 | 608
Muscle hypotonia 5 | 571
Nonsyndromic deafness 5 | 142
Usher Syndrome, Type 1 5 | 7
lung adenocarcinoma 5 | 2,716
oligodendroglioma 5 | 2,850
subependymal giant cell astrocytoma 5 | 2,287
Abnormal color vision 4 | 31
Abnormal vision 4 | 52
Breast cancer 4 | 3,578
Color vision defect 4 | 33
Color vision defect, severe 4 | 31
Congenital stationary night blindness 4 | 29
Hemianopsia 4 | 15
Melanoma 4 | 711
Motor delay 4 | 147
Myopia 4 | 176
No development of motor milestones 4 | 147
Pick disease 4 | 1,894
Pigmentary iris degeneration 4 | 20
Reduced visual acuity 4 | 63
Retinal blind spot 4 | 11
Scotoma 4 | 22
Seizures 4 | 596
Sensorineural hearing loss 4 | 106
Usher Syndrome, Type I 4 | 6
active ulcerative colitis 4 | 764
facioscapulohumeral dystrophy 4 | 288
group 4 medulloblastoma 4 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
pancreatic cancer 4 | 2,398
Asthma 3 | 385

Tissue

Endocrine System 37 | 18,159
Digestive Tract 33 | 17,369
Skin and soft tissues 33 | 17,230
Male tissues 31 | 17,142
Blood and immune system 30 | 16,909
Female tissues 30 | 17,400
Nervous System 30 | 16,725
Urinary Tract 29 | 16,678
Liver and Pancreas 27 | 16,750
Respiratory system 27 | 16,393
Cardiovascular System 24 | 15,192

Target Family

Non-IDG 29 | 12,091
Enzyme 6 | 4,145
GPCR 1 | 408
Kinase 1 | 634
Transcription Factor 1 | 1,400

GO Component

photoreceptor inner segment 38 | 38
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Bardet-Biedl syndrome 4 protein BBS4 Tbio Non-IDG -1.53435 31.5 200
Harmonin USH1C Tbio Non-IDG -2.10689 124.7 188
Unconventional myosin-VIIa MYO7A Tbio Non-IDG -2.14713 133.5 129
Uncharacterized protein C2orf71 C2orf71 Tbio Non-IDG -0.91200 8.96 29
Protein TALPID3 KIAA0586 Tbio Non-IDG -1.37246 24.8 7
Aryl-hydrocarbon-interacting protein-like 1 AIPL1 Tbio Non-IDG -1.73867 59.0 229
Guanine nucleotide-binding protein G(t) subunit alpha-3 GNAT3 Tbio Non-IDG -2.28370 189.3 111
Arrestin-C ARR3 Tbio Non-IDG -1.99324 86.3 161
PH domain leucine-rich repeat-containing protein phosphatase 2 PHLPP2 Tbio Enzyme -1.37775 18.4 122
Guanylyl cyclase-activating protein 2 GUCA1B Tbio Enzyme -1.63232 42.4 122