Development Level

Tbio 15 | 11,445
Tchem 3 | 1,598
Tclin 3 | 613
Tdark 1 | 6,588

IMPC Phenotype

abnormal heart morphology 2 | 162
enlarged heart 2 | 210
abnormal behavior 1 | 298
abnormal whole-body plethysmog... 1 | 4
decreased body weight 1 | 161
decreased circulating amylase ... 1 | 28
decreased circulating triglyce... 1 | 79
decreased lymphocyte cell numb... 1 | 83
hyperactivity 1 | 148
hypoactivity 1 | 132
increased blood uric acid leve... 1 | 5
increased cellular hemoglobin ... 1 | 1
increased circulating potassiu... 1 | 29
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
macrophthalmia 1 | 2
prolonged PR interval 1 | 15
vertebral fusion 1 | 23

Disease

Carcinoma 16 | 11,493
Night Blindness 12 | 101
Difficulties with night vision 11 | 87
Photodysphoria 11 | 121
Photophobia 11 | 121
Retinitis Pigmentosa 11 | 226
Abnormality of retinal pigmentation 10 | 111
Retinal pigment epithelial abnormality 10 | 111
Cone dystrophy 9 | 71
Nystagmus 9 | 317
Autosomal recessive predisposition 8 | 1,442
Blindness 8 | 88
Electroretinogram abnormal 8 | 95
Fundus dystrophy 8 | 83
Intellectual disability 8 | 1,016
Reduced visual acuity 8 | 63
Retinal Degeneration 8 | 106
Blind Vision 7 | 111
Blindness, Legal 7 | 110
Cataract 7 | 297
Dull intelligence 7 | 645
Glaucoma 7 | 239
Keratoconus 7 | 113
Leber congenital amaurosis 7 | 69
Lens Opacities 7 | 231
Low Vision 7 | 174
Low intelligence 7 | 645
Mental Retardation 7 | 645
Mental deficiency 7 | 645
Poor school performance 7 | 645
Sensorineural Hearing Loss (disorder) 7 | 284
Visual Impairment 7 | 174
osteosarcoma 7 | 7,950
Abnormality of the retinal vasculature 6 | 59
Anteverted nostril 6 | 191
Atypical scarring of skin 6 | 62
Broad flat nasal bridge 6 | 236
Conductive hearing loss 6 | 123
Congenital anomaly of testis 6 | 52
Congenital hypoplasia of penis 6 | 176
Hyperinsulinism 6 | 133
Hypogonadism 6 | 173
Nasal bridge wide 6 | 236
Night blindness, progressive 6 | 51
Obesity 6 | 678
Ophthalmoplegia 6 | 106
Optic Atrophy 6 | 242
cone-rod dystrophy 6 | 59
psoriasis 6 | 6,694
Abnormal color vision 5 | 31
Abnormality of macular pigmentation 5 | 16
Color vision defect 5 | 33
Color vision defect, severe 5 | 31
Macular pigmentary changes 5 | 16
Congenital stationary night blindness 4 | 29
Hypoplasia of optic disc 4 | 12
Night blindness, congenital stationary 4 | 16
Night blindness, congenital stationary, complete 4 | 10
Night blindness, stationary 4 | 10
Oguchi disease 4 | 10
Severe myopia 4 | 22
lung adenocarcinoma 4 | 2,716
Atrial Fibrillation 3 | 124
Attenuation of retinal blood vessels 3 | 16
Chronic heart failure 3 | 46
Color blindness 3 | 5
Cone/cone-rod dystrophy 3 | 20
Kidney cancer 3 | 2,613
Myocardial Perfusion Imaging Adjunct 3 | 25
Myopia 3 | 176
Pallor of optic disc 3 | 39
Partial central choroid dystrophy 3 | 11
Platelet Aggregation Inhibition 3 | 22
Prevention of Cerebral Thrombosis 3 | 29
group 3 medulloblastoma 3 | 4,104
medulloblastoma, large-cell 3 | 6,241
Achromatopsia incomplete, X-linked 2 | 2
Age related macular degeneration 2 | 72
Blue Cone Monochromacy 2 | 2
Blue cone monochromatism 2 | 2
Bradyopsia 2 | 10
Breast cancer 2 | 3,578
Cone monochromatism 2 | 2
Decreased amplitudes on flash visual electroretinogram 2 | 13
Diabetic retinopathy 2 | 56
Fundus albipunctatus 2 | 10
Fundus with peripheral 'bony spicules' 2 | 12
Loss of peripheral vision 2 | 5
Nystagmus, continuous pendular 2 | 14
Pendular Nystagmus 2 | 14
Tunnel visual field constriction 2 | 5
Visual field constriction 2 | 36
X- linked recessive 2 | 110
astrocytic glioma 2 | 2,597
atypical teratoid / rhabdoid tumor 2 | 5,112
ependymoma 2 | 4,679
group 4 medulloblastoma 2 | 1,855
pancreatic cancer 2 | 2,398
pituitary cancer 2 | 1,972
primary pancreatic ductal adenocarcinoma 2 | 1,109

Tissue

Endocrine System 20 | 18,159
Digestive Tract 18 | 17,369
Skin and soft tissues 16 | 17,230
Nervous System 15 | 16,725
Blood and immune system 14 | 16,909
Female tissues 13 | 17,400
Urinary Tract 13 | 16,678
Cardiovascular System 12 | 15,192
Liver and Pancreas 11 | 16,750
Male tissues 11 | 17,142
Respiratory system 10 | 16,393

Target Family

Enzyme 6 | 4,145
GPCR 5 | 408
Kinase 5 | 634
Non-IDG 5 | 12,091
Transporter 1 | 473

GO Component

photoreceptor disc membrane 22 | 22
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Retinal guanylyl cyclase 1 GUCY2D Tbio Kinase -2.20658 167.7 205
Guanylyl cyclase-activating protein 3 GUCA1C Tdark Enzyme 0.02 1.10 125
Rhodopsin kinase GRK7 Tchem Kinase -1.83396 45.0 180
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha PDE6A Tclin Enzyme -1.29228 20.3 111
Retinal guanylyl cyclase 2 GUCY2F Tbio Kinase -1.00236 7.60 84
Short-wave-sensitive opsin 1 OPN1SW Tbio GPCR -2.00658 96.9 26
Guanylyl cyclase-activating protein 2 GUCA1B Tbio Enzyme -1.63232 42.4 122
G protein-coupled receptor kinase 4 GRK4 Tchem Kinase -1.71379 54.8 171
Guanylyl cyclase-activating protein 1 GUCA1A Tbio Enzyme -1.91695 89.7 135
Retinal-specific ATP-binding cassette transporter ABCA4 Tbio Transporter -2.71831 511.1 119