Development Level

Tbio 131 | 11,651
Tchem 4 | 1,388
Tdark 3 | 6,593

IMPC Phenotype

preweaning lethality, complete... 8 | 979
embryonic lethality prior to o... 5 | 239
embryonic lethality prior to t... 5 | 278
decreased total body fat amoun... 4 | 207
preweaning lethality, incomple... 4 | 499
decreased blood urea nitrogen ... 2 | 51
decreased circulating aspartat... 2 | 34
decreased circulating triglyce... 2 | 79
decreased lymphocyte cell numb... 2 | 83
hydrometra 2 | 53
increased bone mineral content 2 | 108
increased mean corpuscular vol... 2 | 92
abnormal behavioral response t... 1 | 66
abnormal body wall morphology 1 | 9
abnormal craniofacial morpholo... 1 | 33
abnormal embryo size 1 | 220
abnormal facial morphology 1 | 17
abnormal kidney morphology 1 | 65
abnormal lens morphology 1 | 81
abnormal limb bud morphology 1 | 17
abnormal limb morphology 1 | 13
abnormal retina morphology 1 | 71
abnormal seminal vesicle morph... 1 | 114
abnormal skin morphology 1 | 50
abnormal sleep behavior 1 | 70
abnormal vibrissa morphology 1 | 25
anophthalmia 1 | 33
cardiovascular system phenotyp... 1 | 36
cataract 1 | 92
cleft palate 1 | 8
decreased body length 1 | 101
decreased body weight 1 | 161
decreased circulating alanine ... 1 | 47
decreased circulating amylase ... 1 | 28
decreased circulating insulin ... 1 | 76
decreased grip strength 1 | 116
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular vol... 1 | 79
edema 1 | 59
embryonic growth retardation 1 | 106
enlarged heart 1 | 210
facial cleft 1 | 3
impaired righting response 1 | 26
increased circulating potassiu... 1 | 29
increased circulating sodium l... 1 | 71
increased erythrocyte cell num... 1 | 39
increased hematocrit 1 | 46
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 96
increased mean corpuscular hem... 1 | 36
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
increased spleen weight 1 | 10
increased startle reflex 1 | 112
persistence of hyaloid vascula... 1 | 33
polydactyly 1 | 7
prenatal lethality 1 | 28
prenatal lethality prior to he... 1 | 87
prolonged PR interval 1 | 15
short tibia 1 | 97
small superior vagus ganglion 1 | 74
stereotypic behavior 1 | 3
trunk curl 1 | 16

Disease

Cancer 86 | 2,499
psoriasis 83 | 6,694
Ankylosing spondylitis 72 | 140
Behcet's disease 70 | 89
Carcinoma 66 | 11,493
diabetes mellitus 64 | 1,728
Arthritis 59 | 290
Hypersensitivity reaction type II disease 58 | 253
Acquired immunodeficiency syndrome 57 | 197
Juvenile rheumatoid arthritis 57 | 111
Uveitis 57 | 103
Herpes zoster 56 | 68
Human immunodeficiency virus infectious disease 51 | 138
Stevens-Johnson syndrome 50 | 92
Psoriatic arthritis 49 | 86
ovarian cancer 46 | 8,520
dermatomyositis 45 | 966
Rheumatoid arthritis 42 | 1,191
glioblastoma 41 | 5,792
osteosarcoma 37 | 7,950
Dermatitis 36 | 157
tuberculosis 36 | 2,010
Behcet's syndrome 35 | 50
Congenital adrenal hyperplasia 35 | 73
Nephritis 35 | 51
Retinal vasculitis 35 | 36
Spondyloarthropathy, Susceptibility To, 1 35 | 35
Synovitis 35 | 78
Takayasu's arteritis 35 | 53
drug-induced hepatitis 35 | 44
lung cancer 32 | 4,740
medulloblastoma, large-cell 32 | 6,241
Astrocytoma, Pilocytic 28 | 3,081
Kidney disease 28 | 430
Anemia 27 | 365
lung carcinoma 27 | 2,843
Leprosy 25 | 73
Multiple Sclerosis 24 | 540
Hemochromatosis 23 | 54
Liver disease 23 | 237
Birdshot chorioretinopathy 21 | 23
Hepatitis B 21 | 108
Primary immunodeficiency disease 21 | 54
Skin disease 21 | 66
ependymoma 19 | 4,679
subependymal giant cell astrocytoma 19 | 2,287
atypical teratoid / rhabdoid tumor 18 | 5,112
Multiple myeloma 17 | 1,332
invasive ductal carcinoma 17 | 2,951
juvenile dermatomyositis 17 | 1,187
malignant mesothelioma 17 | 3,232
Pre-Eclampsia 15 | 68
Human immunodeficiency virus type 1, susceptibility to 14 | 26
Psoriasis susceptibility 1 14 | 14
cutaneous lupus erythematosus 14 | 1,057
pancreatic cancer 14 | 2,398
Breast cancer 13 | 3,578
adult high grade glioma 13 | 3,801
astrocytoma 13 | 1,146
group 4 medulloblastoma 13 | 1,855
interstitial cystitis 13 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 13 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 12 | 2,955
non-small cell lung cancer 12 | 2,890
ulcerative colitis 12 | 1,819
Autosomal recessive predisposition 11 | 1,442
Schizophrenia 11 | 1,160
intraductal papillary-mucinous neoplasm (IPMN) 10 | 3,291
primary Sjogren syndrome 10 | 735
Liver Cirrhosis, Experimental 9 | 769
active Crohn's disease 9 | 922
breast carcinoma 9 | 1,638
group 3 medulloblastoma 9 | 4,104
lung adenocarcinoma 9 | 2,716
oligodendroglioma 9 | 2,850
pediatric high grade glioma 9 | 1,064
primitive neuroectodermal tumor 9 | 3,035
Kidney cancer 8 | 2,613
active ulcerative colitis 8 | 764
pituitary cancer 8 | 1,972
posterior fossa group A ependymoma 8 | 468
primary pancreatic ductal adenocarcinoma 8 | 1,109
Bipolar Disorder 7 | 666
Duchenne muscular dystrophy 7 | 601
esophageal adenocarcinoma 7 | 737
pancreatic ductal adenocarcinoma liver metastasis 7 | 1,962
Neurodegenerative disease 6 | 414
astrocytic glioma 6 | 2,597
cystic fibrosis 6 | 1,696
Down syndrome 5 | 499
Intellectual disability 5 | 1,016
Myocardial Ischemia 5 | 169
Pick disease 5 | 1,894
Splenomegaly 5 | 190
Waldenstrons macroglobulinemia 5 | 765
acute myeloid leukemia 5 | 783
adrenocortical carcinoma 5 | 1,428
aldosterone-producing adenoma 5 | 665
colon cancer 5 | 1,478
mucosa-associated lymphoid tissue lymphoma 5 | 484

Tissue

Digestive Tract 68 | 17,369
Endocrine System 68 | 18,159
Female tissues 68 | 17,400
Respiratory system 68 | 16,393
Blood and immune system 67 | 16,909
Liver and Pancreas 67 | 16,750
Male tissues 67 | 17,142
Nervous System 67 | 16,725
Skin and soft tissues 67 | 17,230
Urinary Tract 67 | 16,678
Cardiovascular System 64 | 15,192

Target Family

Non-IDG 100 | 12,091
Enzyme 33 | 4,145
Ion Channel 2 | 344
Kinase 2 | 634
Transporter 1 | 473

GO Component

phagocytic vesicle membrane 138 | 138
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Ras-related protein Rab-22A RAB22A Tbio Enzyme -1.40824 19.7 123
HLA class I histocompatibility antigen, A-25 alpha chain HLA-A Tbio Non-IDG -2.41667 4123.8 0
HLA class I histocompatibility antigen, B-51 alpha chain HLA-B Tbio Non-IDG -1.88752 1613.5 0
HLA class I histocompatibility antigen, B-37 alpha chain HLA-B Tbio Non-IDG -1.88752 1613.5 0
Vesicle-associated membrane protein 8 VAMP8 Tbio Non-IDG -1.79654 64.6 107
Ras-related protein Rab-23 RAB23 Tbio Enzyme -1.63391 45.2 211
Ras-related protein Rab-32 RAB32 Tbio Enzyme -1.46660 33.4 127
Ras-related protein Rab-31 RAB31 Tbio Enzyme -1.12978 14.8 109
V-type proton ATPase 116 kDa subunit a isoform 2 ATP6V0A2 Tbio Enzyme -2.46402 298.9 76
HLA class I histocompatibility antigen, alpha chain G HLA-G Tbio Non-IDG -3.09525 1317.6 913