Development Level

Tbio 68 | 10,625
Tchem 17 | 1,890
Tdark 12 | 7,003
Tclin 1 | 602

IMPC Phenotype

decreased body weight 4 | 174
decreased circulating choleste... 3 | 85
decreased total body fat amoun... 3 | 186
preweaning lethality, complete... 3 | 633
abnormal behavior 2 | 226
abnormal lens morphology 2 | 73
decreased circulating HDL chol... 2 | 77
decreased circulating alanine ... 2 | 53
decreased circulating aspartat... 2 | 27
increased circulating chloride... 2 | 43
increased sacral vertebrae num... 2 | 62
abnormal coat appearance 1 | 25
abnormal coat- hair morphology 1 | 18
abnormal cornea morphology 1 | 24
abnormal cranium morphology 1 | 32
abnormal digit morphology 1 | 13
abnormal eye morphology 1 | 38
abnormal eye size 1 | 11
abnormal hair texture 1 | 4
abnormal heart morphology 1 | 51
abnormal incisor morphology 1 | 3
abnormal kidney morphology 1 | 30
abnormal maxilla morphology 1 | 16
abnormal response to new envir... 1 | 8
abnormal response to tactile s... 1 | 16
abnormal retina morphology 1 | 100
abnormal retinal vasculature m... 1 | 15
abnormal seminal vesicle morph... 1 | 47
abnormal sleep behavior 1 | 63
abnormal tail morphology 1 | 17
cardiovascular system phenotyp... 1 | 35
cataract 1 | 26
decreased Ly6C low monocyte nu... 1 | 23
decreased caudal vertebrae num... 1 | 49
decreased circulating LDL chol... 1 | 37
decreased circulating fructosa... 1 | 31
decreased circulating serum al... 1 | 79
decreased circulating total pr... 1 | 41
decreased eosinophil cell numb... 1 | 41
decreased erythrocyte cell num... 1 | 43
decreased heart rate variabili... 1 | 11
decreased hemoglobin content 1 | 53
decreased lean body mass 1 | 195
decreased leukocyte cell numbe... 1 | 54
decreased lumbar vertebrae num... 1 | 62
decreased mean corpuscular vol... 1 | 50
decreased prepulse inhibition 1 | 52
decreased vertical activity 1 | 22
enlarged heart 1 | 111
enlarged spleen 1 | 26
female infertility 1 | 34
hypoactivity 1 | 89
increased Ly6C high monocyte n... 1 | 12
increased blood uric acid leve... 1 | 5
increased bone mineral density 1 | 52
increased circulating amylase ... 1 | 13
increased circulating fructosa... 1 | 11
increased circulating insulin ... 1 | 2
increased circulating sodium l... 1 | 71
increased granulocyte number 1 | 8
increased heart rate 1 | 17
increased heart weight 1 | 37
increased lean body mass 1 | 107
increased mean corpuscular hem... 1 | 93
increased mean corpuscular vol... 1 | 91
increased red blood cell distr... 1 | 21
increased startle reflex 1 | 38
persistence of hyaloid vascula... 1 | 22
shortened RR interval 1 | 19

Disease

ovarian cancer 56 | 8,491
osteosarcoma 46 | 7,933
medulloblastoma, large-cell 36 | 6,234
psoriasis 35 | 6,685
pancreatic ductal adenocarcinoma liver metastasis 32 | 1,795
Zellweger Syndrome 27 | 38
glioblastoma 27 | 5,572
lung cancer 25 | 4,473
intraductal papillary-mucinous neoplasm (IPMN) 24 | 3,289
atypical teratoid / rhabdoid tumor 23 | 4,369
ulcerative colitis 22 | 2,087
Infantile refsum disease 19 | 23
intraductal papillary-mucinous adenoma (IPMA) 19 | 2,956
invasive ductal carcinoma 19 | 2,950
malignant mesothelioma 18 | 3,163
Adrenoleukodystrophy 17 | 31
Peroxisomal disease 17 | 20
interstitial cystitis 17 | 2,299
Chondrodysplasia punctata 16 | 41
ependymoma 14 | 2,514
subependymal giant cell astrocytoma 14 | 2,287
Neonatal adrenoleukodystrophy 13 | 14
ductal carcinoma in situ 13 | 1,745
intraductal papillary-mucinous carcinoma (IPMC) 13 | 2,988
lung adenocarcinoma 13 | 2,714
lung carcinoma 13 | 2,844
non-small cell lung cancer 13 | 2,798
tuberculosis 13 | 1,563
Adrenoleukodystrophy, Neonatal 12 | 13
Breast cancer 12 | 3,098
Infantile Refsum Disease (disorder) 12 | 13
Refsum disease 12 | 21
astrocytic glioma 12 | 2,241
oligodendroglioma 12 | 2,849
posterior fossa group B ependymoma 12 | 1,530
primitive neuroectodermal tumor 12 | 3,031
Multiple myeloma 11 | 1,327
astrocytoma 11 | 1,493
group 4 medulloblastoma 11 | 1,875
pancreatic cancer 11 | 2,300
Carcinoma 10 | 2,147
Peroxisome Biogenesis Disorder 1A (Zellweger) 10 | 12
Peroxisome Biogenesis Disorder 3B 10 | 11
Peroxisome biogenesis disorders 10 | 11
Pick disease 10 | 1,893
pediatric high grade glioma 10 | 2,712
pilocytic astrocytoma 10 | 3,086
Atopic dermatitis 9 | 944
Cancer 9 | 2,346
Rhizomelic chondrodysplasia punctata 8 | 11
Waldenstrons macroglobulinemia 8 | 764
colon cancer 8 | 1,475
diabetes mellitus 8 | 1,663
progressive supranuclear palsy 8 | 674
adult high grade glioma 7 | 2,148
cystic fibrosis 7 | 1,670
pituitary cancer 7 | 1,972
posterior fossa group A ependymoma 7 | 1,511
Cataract 6 | 104
acute quadriplegic myopathy 6 | 1,157
adrenocortical carcinoma 6 | 1,427
aldosterone-producing adenoma 6 | 664
medulloblastoma 6 | 1,524
primary pancreatic ductal adenocarcinoma 6 | 1,271
Alzheimer's disease 5 | 644
Down syndrome 5 | 548
Heart failure 5 | 80
Intellectual disability 5 | 573
Neonatal adrenoleucodystrophy 5 | 5
PEROXISOME BIOGENESIS DISORDER 2B 5 | 5
Parkinson's disease 5 | 364
Reperfusion Injury 5 | 84
Vascular disease 5 | 281
gastric carcinoma 5 | 832
nephrosclerosis 5 | 329
sonic hedgehog group medulloblastoma 5 | 1,482
Asthma 4 | 349
Autistic Disorder 4 | 320
Colorectal Neoplasms 4 | 217
Crohn's disease 4 | 304
Diabetes Mellitus, Experimental 4 | 106
Glioma 4 | 66
Hypertensive disease 4 | 193
IGA Glomerulonephritis 4 | 454
Neoplastic Cell Transformation 4 | 81
Peroxisomal acyl-CoA oxidase deficiency 4 | 4
Prostatic Neoplasms 4 | 471
Rheumatoid Arthritis 4 | 1,170
active Crohn's disease 4 | 918
acute myeloid leukemia 4 | 785
atypical teratoid/rhabdoid tumor 4 | 1,095
autosomal dominant Emery-Dreifuss muscular dystrophy 4 | 499
breast carcinoma 4 | 1,614
fibroadenoma 4 | 557
group 3 medulloblastoma 4 | 2,254
hereditary spastic paraplegia 4 | 313
spina bifida 4 | 1,064
dermatomyositis 3 | 966
esophageal adenocarcinoma 3 | 737
juvenile dermatomyositis 3 | 1,189

Tissue

Blood and immune system 98 | 17,994
Cardiovascular System 98 | 17,957
Digestive Tract 98 | 18,472
Endocrine System 98 | 18,511
Female tissues 98 | 18,646
Liver and Pancreas 98 | 18,135
Nervous System 98 | 18,560
Skin and soft tissues 98 | 18,114
Urinary Tract 98 | 18,443
Male tissues 97 | 17,968
Respiratory system 97 | 17,483

Target Family

Enzyme 60 | 4,146
Non-IDG 33 | 11,969
Transporter 5 | 473

GO Component

peroxisome 98 | 98
nucleus 5,106 | 5,106
cytoplasm 4,984 | 4,984
plasma membrane 4,118 | 4,118
integral component of membrane 3,679 | 3,679
cytosol 3,264 | 3,264
extracellular exosome 2,757 | 2,757
nucleoplasm 2,716 | 2,716
membrane 1,906 | 1,906
extracellular region 1,493 | 1,493
integral component of plasma m... 1,406 | 1,406
extracellular space 1,304 | 1,304
mitochondrion 1,231 | 1,231
Golgi apparatus 864 | 864
endoplasmic reticulum 859 | 859
endoplasmic reticulum membrane 848 | 848
nucleolus 815 | 815
Golgi membrane 659 | 659
perinuclear region of cytoplas... 611 | 611
cell surface 594 | 594
intracellular 548 | 548
intracellular membrane-bounded... 536 | 536
cell junction 451 | 451
mitochondrial inner membrane 425 | 425
centrosome 409 | 409
focal adhesion 383 | 383
protein complex 355 | 355
cytoskeleton 343 | 343
dendrite 329 | 329
mitochondrial matrix 322 | 322
cell-cell adherens junction 307 | 307
neuronal cell body 303 | 303
microtubule 294 | 294
lysosomal membrane 278 | 278
apical plasma membrane 277 | 277
proteinaceous extracellular ma... 244 | 244
neuron projection 229 | 229
nuclear membrane 218 | 218
early endosome 217 | 217
axon 214 | 214
lysosome 210 | 210
endosome 208 | 208
actin cytoskeleton 205 | 205
external side of plasma membra... 205 | 205
postsynaptic membrane 204 | 204
extracellular matrix 198 | 198
nuclear speck 197 | 197
membrane raft 196 | 196
endoplasmic reticulum lumen 192 | 192
transcription factor complex 184 | 184
endosome membrane 182 | 182
early endosome membrane 180 | 180
basolateral plasma membrane 174 | 174
nuclear chromatin 169 | 169
synapse 166 | 166
cell-cell junction 161 | 161
nuclear envelope 156 | 156
lamellipodium 153 | 153
mitochondrial outer membrane 148 | 148
blood microparticle 147 | 147
myelin sheath 144 | 144
postsynaptic density 144 | 144
cytoplasmic vesicle 143 | 143
microtubule organizing center 137 | 137
cytoplasmic, membrane-bounded ... 132 | 132
ER to Golgi transport vesicle ... 131 | 131
microtubule cytoskeleton 127 | 127
receptor complex 127 | 127
phagocytic vesicle membrane 126 | 126
cytoplasmic vesicle membrane 125 | 125
midbody 125 | 125
trans-Golgi network 124 | 124
cell cortex 119 | 119
cilium 118 | 118
late endosome 116 | 116
spindle 116 | 116
intracellular ribonucleoprotei... 114 | 114
vesicle 112 | 112
Z disc 110 | 110
bicellular tight junction 110 | 110
anchored component of membrane 109 | 109
growth cone 109 | 109
integral component of lumenal ... 108 | 108
late endosome membrane 107 | 107
endomembrane system 106 | 106
centriole 105 | 105
recycling endosome 104 | 104
spindle pole 104 | 104
perikaryon 103 | 103
integral component of endoplas... 101 | 101
intermediate filament 101 | 101
melanosome 101 | 101
chromosome 100 | 100
dendritic spine 99 | 99
ubiquitin ligase complex 99 | 99
nuclear matrix 97 | 97
PML body 94 | 94
Golgi lumen 93 | 93
keratin filament 93 | 93
trans-Golgi network membrane 92 | 92

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Protein Mpv17 MPV17 Tbio Non-IDG -1.63162 40.5 114
Hydroxyacid oxidase 1 HAO1 Tchem Enzyme -2.99254 984.0 189
Transmembrane protein 135 TMEM135 Tdark Non-IDG -0.56834 3.33 30
Synaptotagmin-7 SYT7 Tbio Non-IDG -1.72363 48.4 144
Peroxisomal trans-2-enoyl-CoA reductase PECR Tbio Enzyme -1.60889 41.8 84
Isopentenyl-diphosphate delta-isomerase 2 IDI2 Tbio Enzyme -1.22617 20.3 66
Isopentenyl-diphosphate Delta-isomerase 1 IDI1 Tbio Enzyme -1.59059 37.3 107
Mpv17-like protein MPV17L Tbio Non-IDG -0.84973 7.93 20
E3 ubiquitin-protein ligase TRIM37 TRIM37 Tbio Enzyme -3.25549 1722.7 162
Hydroxyacid oxidase 2 HAO2 Tchem Enzyme -1.21219 15.8 48