Development Level

Tbio 30 | 11,445
Tchem 11 | 1,598
Tdark 4 | 6,588

IMPC Phenotype

decreased circulating choleste... 3 | 93
decreased vertical activity 3 | 208
preweaning lethality, incomple... 3 | 499
abnormal heart morphology 2 | 162
decreased mean corpuscular vol... 2 | 79
decreased total body fat amoun... 2 | 207
enlarged heart 2 | 210
abnormal behavior 1 | 298
abnormal coat appearance 1 | 31
abnormal cranium morphology 1 | 36
abnormal hair texture 1 | 4
abnormal incisor morphology 1 | 4
abnormal maxilla morphology 1 | 17
abnormal skin morphology 1 | 50
abnormal sleep behavior 1 | 70
cardiovascular system phenotyp... 1 | 36
decreased body weight 1 | 161
decreased caudal vertebrae num... 1 | 53
decreased circulating HDL chol... 1 | 68
decreased circulating alanine ... 1 | 47
decreased circulating aspartat... 1 | 34
decreased coping response 1 | 8
decreased heart rate variabili... 1 | 13
decreased lactate dehydrogenas... 1 | 16
decreased large unstained cell... 1 | 11
hypoactivity 1 | 132
increased circulating amylase ... 1 | 25
increased circulating bilirubi... 1 | 16
increased heart rate 1 | 23
increased heart weight 1 | 62
increased lean body mass 1 | 172
increased total body fat amoun... 1 | 134
shortened RR interval 1 | 17

Disease

Carcinoma 33 | 11,493
ovarian cancer 27 | 8,520
pancreatic ductal adenocarcinoma liver metastasis 22 | 1,962
psoriasis 22 | 6,694
osteosarcoma 18 | 7,950
medulloblastoma, large-cell 16 | 6,241
Autosomal recessive predisposition 15 | 1,442
glioblastoma 15 | 5,792
Zellweger syndrome 12 | 37
atypical teratoid / rhabdoid tumor 12 | 5,112
ependymoma 12 | 4,679
interstitial cystitis 12 | 2,312
intraductal papillary-mucinous neoplasm (IPMN) 12 | 3,291
lung cancer 11 | 4,740
malignant mesothelioma 11 | 3,232
Chondrodysplasia punctata 10 | 41
intraductal papillary-mucinous adenoma (IPMA) 10 | 2,955
invasive ductal carcinoma 9 | 2,951
ulcerative colitis 9 | 1,819
Adrenoleukodystrophy 8 | 29
Refsum disease 8 | 20
astrocytic glioma 8 | 2,597
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,989
Cholestasis 7 | 155
Epilepsy 7 | 792
Failure to gain weight 7 | 365
Infantile Refsum disease 7 | 23
Liver Cirrhosis, Experimental 7 | 769
Neuropathy 7 | 261
Pediatric failure to thrive 7 | 365
Schizophrenia 7 | 1,160
Seizures 7 | 596
adult high grade glioma 7 | 3,801
diabetes mellitus 7 | 1,728
oligodendroglioma 7 | 2,850
subependymal giant cell astrocytoma 7 | 2,287
Atopic dermatitis 6 | 952
Breast cancer 6 | 3,578
Cataract 6 | 297
Muscle hypotonia 6 | 571
Peripheral Neuropathy 6 | 134
Rhizomelic chondrodysplasia punctata 6 | 11
Sensorineural Hearing Loss (disorder) 6 | 284
Waldenstrons macroglobulinemia 6 | 765
alpha-methylacyl-CoA racemase deficiency 6 | 9
group 3 medulloblastoma 6 | 4,104
lung adenocarcinoma 6 | 2,716
primitive neuroectodermal tumor 6 | 3,035
tuberculosis 6 | 2,010
Astrocytoma, Pilocytic 5 | 3,081
Concave bridge of nose 5 | 195
Depressed nasal bridge 5 | 195
Depressed nasal root/bridge 5 | 195
Hepatomegaly 5 | 285
Kidney disease 5 | 430
Low Vision 5 | 174
Multiple myeloma 5 | 1,332
Nystagmus 5 | 317
Peroxisomal disease 5 | 22
Retinitis Pigmentosa 5 | 226
Short stature 5 | 531
Visual Impairment 5 | 174
lung carcinoma 5 | 2,843
nephrosclerosis 5 | 333
non-small cell lung cancer 5 | 2,890
pancreatic cancer 5 | 2,398
Cancer 4 | 2,499
Cerebellar Ataxia 4 | 304
Cognitive delay 4 | 608
Congenital pes cavus 4 | 88
Developmental regression 4 | 95
Elevated hepatic transaminases 4 | 81
Frontal bossing 4 | 157
Global developmental delay 4 | 608
Hepatic enzyme increased 4 | 81
Hypoplastic mandible condyle 4 | 275
Lens Opacities 4 | 231
Liver Dysfunction 4 | 99
Liver enzymes abnormal 4 | 81
Liver function test increased 4 | 81
Liver function tests abnormal finding 4 | 81
Loss of developmental milestones 4 | 95
Mandibular hypoplasia 4 | 275
Mental and motor retardation 4 | 608
Mental deterioration in childhood 4 | 95
Micrognathism 4 | 275
Muscle Spasticity 4 | 195
Neurodevelopmental regression 4 | 95
Pick disease 4 | 1,894
Primary hyperoxaluria 4 | 15
Psychomotor regression 4 | 95
Psychomotor regression beginning in infancy 4 | 95
Psychomotor regression in infants 4 | 95
Psychomotor regression, progressive 4 | 95
Subclinical abnormal liver function tests 4 | 81
Transaminases increased 4 | 81
astrocytoma 4 | 1,146
colon cancer 4 | 1,478
ductal carcinoma in situ 4 | 1,745
pituitary cancer 4 | 1,972

Tissue

Liver and Pancreas 45 | 16,750
Urinary Tract 45 | 16,678
Blood and immune system 44 | 16,909
Digestive Tract 44 | 17,369
Endocrine System 44 | 18,159
Skin and soft tissues 44 | 17,230
Female tissues 43 | 17,400
Nervous System 43 | 16,725
Male tissues 42 | 17,142
Respiratory system 42 | 16,393
Cardiovascular System 39 | 15,192

Target Family

Enzyme 35 | 4,145
Non-IDG 9 | 12,091
Transporter 1 | 473

GO Component

peroxisomal matrix 45 | 45
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Lon protease homolog 2, peroxisomal LONP2 Tbio Enzyme -1.00177 8.20 100
ATP-binding cassette sub-family D member 3 ABCD3 Tbio Transporter -1.82051 64.2 166
Acyl-coenzyme A oxidase-like protein ACOXL Tdark Enzyme -0.18122 1.46 28
Malonyl-CoA decarboxylase, mitochondrial MLYCD Tchem Enzyme -1.70434 46.1 67
Acyl-coenzyme A thioesterase 4 ACOT4 Tbio Enzyme -0.53787 2.87 58
Ketimine reductase mu-crystallin CRYM Tbio Enzyme -1.70644 52.5 199
Peroxisomal targeting signal 1 receptor PEX5 Tbio Non-IDG -2.43126 272.8 138
Insulin-degrading enzyme IDE Tchem Enzyme -2.57779 392.8 331
Fatty acyl-CoA reductase 1 FAR1 Tbio Enzyme -1.65427 43.8 27
Nucleoside diphosphate-linked moiety X motif 19 NUDT19 Tdark Non-IDG 0.90 0.09 79