Development Level

Tbio 8 | 11,445
Tdark 1 | 6,588

IMPC Phenotype

preweaning lethality, complete... 2 | 979
preweaning lethality, incomple... 2 | 499
abnormal ileum morphology 1 | 2
abnormal lung morphology 1 | 26
decreased fasted circulating g... 1 | 65
decreased total body fat amoun... 1 | 207
edema 1 | 59
increased circulating magnesiu... 1 | 10
increased fasted circulating g... 1 | 76
increased heart weight 1 | 62
increased lean body mass 1 | 172
male infertility 1 | 123
polycystic kidney 1 | 15

Disease

Primary ciliary dyskinesia 7 | 76
Carcinoma 6 | 11,493
Ciliary Dyskinesia, Primary, 1 6 | 27
Ciliary Motility Disorders 6 | 38
Kartagener Syndrome 6 | 38
ependymoma 6 | 4,679
nasopharyngeal carcinoma 5 | 1,058
Male infertility 4 | 206
Situs Inversus 4 | 65
chronic rhinosinusitis 4 | 512
psoriasis 4 | 6,694
Autosomal recessive predisposition 3 | 1,442
Breast cancer 3 | 3,578
Kidney cancer 3 | 2,613
Recurrent respiratory infections 3 | 141
Sinusitis 3 | 65
osteosarcoma 3 | 7,950
ovarian cancer 3 | 8,520
Abnormal respiratory motile cilium morphology 2 | 3
Bronchiectasis 2 | 64
DOID:2627 2 | 94
Endometrial cancer 2 | 311
Endometriosis 2 | 540
Liver cancer 2 | 604
Melanoma 2 | 711
Paranasal Sinus Diseases 2 | 34
Right atrial isomerism 2 | 29
Situs ambiguus 2 | 25
Skin cancer 2 | 469
glioblastoma 2 | 5,792
medulloblastoma, large-cell 2 | 6,241
Abnormal ciliary motility 1 | 2
Absent frontal sinuses 1 | 8
Allergic rhinitis 1 | 94
Alzheimer's disease 1 | 658
Anosmia 1 | 22
Aplasia of frontal sinus 1 | 8
Asthma 1 | 385
Atherosclerosis 1 | 291
Bipolar Disorder 1 | 666
Blastomycosis 1 | 12
CILIARY DYSKINESIA, PRIMARY, 16 1 | 1
CILIARY DYSKINESIA, PRIMARY, 3 1 | 1
CILIARY DYSKINESIA, PRIMARY, 6 1 | 1
CILIARY DYSKINESIA, PRIMARY, 9 1 | 1
Carrion's disease 1 | 6
Chronic otitis media 1 | 52
Chronic rhinitis 1 | 7
Chronic sinus disease 1 | 9
Chronic sinusitis 1 | 9
Ciliary Dyskinesia, Primary, 20 1 | 1
Cocaine-Related Disorders 1 | 92
Communicating Hydrocephalus 1 | 8
Conductive hearing loss 1 | 123
Congenital absence of spleen 1 | 10
Corneal abnormalities 1 | 6
Cornela disease 1 | 6
Cri-Du-Chat syndrome 1 | 16
Headache 1 | 37
Immotile cilia 1 | 2
Immune system cancer 1 | 140
Large intestine cancer 1 | 126
Manic 1 | 14
Multiple myeloma 1 | 1,332
Nasal Polyps 1 | 10
Osteoporosis 1 | 363
Paranoia 1 | 20
Paranoid Disorders 1 | 8
Pick disease 1 | 1,894
Pneumonia 1 | 174
Primary ciliary dyskinesia, 3 1 | 1
Recurrent sinus disease 1 | 22
Recurrent sinusitis 1 | 22
Refractive error 1 | 50
Respiratory cilia have shortened or absent outer dynein arms 1 | 1
Retinitis pigmentosa 11 1 | 59
Rheumatoid arthritis 1 | 1,191
Substance-Related Disorders 1 | 115
adult high grade glioma 1 | 3,801
adult-onset autosomal dominant demyelinating leukodystrophy 1 | 10
cutaneous lupus erythematosus 1 | 1,057
cystic fibrosis and chronic rhinosinusitis 1 | 214
ductal carcinoma in situ 1 | 1,745
ear infection chronic 1 | 52
fibroadenoma 1 | 559
group 3 medulloblastoma 1 | 4,104
group 4 medulloblastoma 1 | 1,855
intraductal papillary-mucinous neoplasm (IPMN) 1 | 3,291
lung adenocarcinoma 1 | 2,716
non-small cell lung cancer 1 | 2,890
pancreatic cancer 1 | 2,398
pediatric high grade glioma 1 | 1,064
pituitary cancer 1 | 1,972
primary ciliary dyskinesia 16 1 | 1
tuberculosis 1 | 2,010

Tissue

Digestive Tract 9 | 17,369
Endocrine System 9 | 18,159
Female tissues 9 | 17,400
Respiratory system 9 | 16,393
Skin and soft tissues 9 | 17,230
Male tissues 8 | 17,142
Nervous System 8 | 16,725
Urinary Tract 8 | 16,678
Blood and immune system 7 | 16,909
Liver and Pancreas 7 | 16,750
Cardiovascular System 3 | 15,192

Target Family

Non-IDG 9 | 12,091

GO Component

outer dynein arm 9 | 9
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Dynein intermediate chain 1, axonemal DNAI1 Tbio Non-IDG -1.90654 78.9 160
Thioredoxin domain-containing protein 3 NME8 Tbio Non-IDG -1.03981 11.2 79
Dynein light chain roadblock-type 1 DYNLRB1 Tbio Non-IDG -2.23639 168.6 41
Dynein light chain roadblock-type 2 DYNLRB2 Tbio Non-IDG -0.65444 2.59 77
Dynein heavy chain 5, axonemal DNAH5 Tbio Non-IDG -1.46000 27.2 32
Coiled-coil domain-containing protein 114 CCDC114 Tbio Non-IDG -0.48311 3.41 56
Dynein heavy chain 8, axonemal DNAH8 Tdark Non-IDG -0.32817 2.51 48
Dynein intermediate chain 2, axonemal DNAI2 Tbio Non-IDG -1.25951 17.0 172
Dynein light chain 1, axonemal DNAL1 Tbio Non-IDG 0.00000 1.00 135