Development Level

Tbio 6 | 11,445

IMPC Phenotype

preweaning lethality, complete... 3 | 979
decreased caudal vertebrae num... 1 | 53
embryonic lethality prior to o... 1 | 239
prenatal lethality prior to he... 1 | 87

Disease

Carcinoma 5 | 11,493
psoriasis 5 | 6,694
Meier-Gorlin syndrome 4 | 10
group 3 medulloblastoma 4 | 4,104
lung cancer 4 | 4,740
Autosomal recessive predisposition 3 | 1,442
Birth length less than 3rd percentile 3 | 6
Congenital hypoplasia of breast 3 | 25
Congenital small ears 3 | 48
Delayed bone age 3 | 136
EAR, PATELLA, SHORT STATURE SYNDROME 3 | 7
Failure to gain weight 3 | 365
Fetal Growth Retardation 3 | 189
Hypertrophy of clitoris 3 | 40
Infant, Small for Gestational Age 3 | 176
Intrauterine retardation 3 | 176
Isolated growth hormone deficiency 3 | 30
Microcephaly 3 | 166
Microstomia 3 | 78
Pediatric failure to thrive 3 | 365
Seckel syndrome 3 | 34
Slender, gracile long tubular bones 3 | 21
Small head 3 | 374
non-small cell lung cancer 3 | 2,890
osteosarcoma 3 | 7,950
ovarian cancer 3 | 8,520
Absent bone maturation in sternum 2 | 4
Absent sternal ossification 2 | 4
Cryptorchidism 2 | 296
Decreased projection of maxilla 2 | 66
Deficiency of upper jaw bones 2 | 66
Feeding difficulties 2 | 127
Full lower lip 2 | 64
Gastroesophageal reflux disease 2 | 110
Genu varum 2 | 29
Heartburn 2 | 78
Hypoplasia of the maxilla 2 | 66
Hypoplastic mandible condyle 2 | 275
Hypotrophic maxilla 2 | 66
Mandibular hypoplasia 2 | 275
Maxillary retrognathia 2 | 66
Micrognathism 2 | 275
Patella aplasia-hypoplasia 2 | 12
Prominent lower lip 2 | 64
Pulmonary emphysema 2 | 48
Retrusion of upper jaw bones 2 | 66
Short ribs 2 | 30
Small labia majora 2 | 16
adrenocortical carcinoma 2 | 1,428
glioblastoma 2 | 5,792
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
malignant mesothelioma 2 | 3,232
medulloblastoma, large-cell 2 | 6,241
Abnormality of pelvic girdle bone morphology 1 | 37
Absent auditory canals 1 | 23
Absent external auditory canals 1 | 23
Atresia of the external auditory canal 1 | 23
Atretic auditory canal 1 | 23
Blepharophimosis 1 | 70
Congenital Camptodactyly 1 | 40
Congenital clubfoot 1 | 109
Congenital deafness 1 | 185
Congenital hemivertebra 1 | 25
Contracture of joint of hand 1 | 30
Curvature of little finger 1 | 110
Deafness 1 | 198
DiGeorge syndrome 1 | 47
Dwarfism 1 | 37
Dyspnea 1 | 76
Frontal bossing 1 | 157
Gout 1 | 106
Hearing Loss, Partial 1 | 185
Infectious disease of lung 1 | 29
Knee joint valgus deformity 1 | 56
Long eyelashes 1 | 37
Long narrow head 1 | 75
Low Birth Weights 1 | 69
Malaria 1 | 160
Microretrognathia 1 | 13
Multiple pulmonary infections 1 | 29
Narrow cranium shape 1 | 75
Narrow head shape 1 | 75
Narrow skull shape 1 | 75
Narrow thorax 1 | 53
Overcurvature of nail 1 | 6
Range of joint movement increased 1 | 32
Recurrent pneumonia 1 | 29
Recurrent pulmonary infections 1 | 29
Respiratory distress 1 | 43
Short palpebral fissure 1 | 38
Short thorax 1 | 21
Small for gestational age (disorder) 1 | 69
Thin rib 1 | 21
Thin skin 1 | 47
Tracheomalacia 1 | 22
Triangular face 1 | 58
Turridolichocephaly 1 | 75
hearing impairment 1 | 199
substance-related disorder 1 | 162
tuberculosis and treatment for 6 months 1 | 409

Tissue

Blood and immune system 6 | 16,909
Cardiovascular System 6 | 15,192
Digestive Tract 6 | 17,369
Endocrine System 6 | 18,159
Female tissues 6 | 17,400
Liver and Pancreas 6 | 16,750
Male tissues 6 | 17,142
Nervous System 6 | 16,725
Respiratory system 6 | 16,393
Skin and soft tissues 6 | 17,230
Urinary Tract 6 | 16,678

Target Family

Non-IDG 6 | 12,091

GO Component

origin recognition complex 6 | 6
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Origin recognition complex subunit 1 ORC1 Tbio Non-IDG -1.42573 28.0 148
Origin recognition complex subunit 2 ORC2 Tbio Non-IDG -0.68275 4.92 168
Origin recognition complex subunit 5 ORC5 Tbio Non-IDG -1.50983 31.3 71
Origin recognition complex subunit 3 ORC3 Tbio Non-IDG -1.25409 17.4 192
Origin recognition complex subunit 6 ORC6 Tbio Non-IDG -1.38268 26.3 165
Origin recognition complex subunit 4 ORC4 Tbio Non-IDG -1.52127 33.7 155