Development Level

Tbio 51 | 11,445
Tchem 18 | 1,598
Tclin 9 | 613
Tdark 8 | 6,588

IMPC Phenotype

hyperactivity 3 | 148
cataract 2 | 92
decreased blood urea nitrogen ... 2 | 51
decreased circulating triglyce... 2 | 79
decreased mean corpuscular vol... 2 | 79
hypoactivity 2 | 132
increased leukocyte cell numbe... 2 | 47
increased startle reflex 2 | 112
preweaning lethality, complete... 2 | 979
abnormal behavior 1 | 298
abnormal lens morphology 1 | 81
abnormal pupil morphology 1 | 2
decreased body weight 1 | 161
decreased circulating iron lev... 1 | 32
decreased circulating serum al... 1 | 82
decreased lean body mass 1 | 135
decreased leukocyte cell numbe... 1 | 73
decreased mean platelet volume 1 | 25
decreased startle reflex 1 | 75
impaired glucose tolerance 1 | 75
impaired pupillary reflex 1 | 26
increased IgA level 1 | 1
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating amylase ... 1 | 25
increased circulating choleste... 1 | 66
increased circulating potassiu... 1 | 29
increased circulating unsatura... 1 | 1
increased mean corpuscular vol... 1 | 92
increased total body fat amoun... 1 | 134
limb grasping 1 | 41
preweaning lethality, incomple... 1 | 499
thrombocytopenia 1 | 56

Disease

Carcinoma 59 | 11,493
psoriasis 48 | 6,694
ovarian cancer 34 | 8,520
lung cancer 28 | 4,740
ependymoma 26 | 4,679
osteosarcoma 26 | 7,950
glioblastoma 25 | 5,792
interstitial cystitis 25 | 2,312
intraductal papillary-mucinous neoplasm (IPMN) 25 | 3,291
medulloblastoma, large-cell 25 | 6,241
intraductal papillary-mucinous adenoma (IPMA) 23 | 2,955
lung carcinoma 22 | 2,843
pancreatic ductal adenocarcinoma liver metastasis 22 | 1,962
Breast cancer 21 | 3,578
Cancer 21 | 2,499
adult high grade glioma 19 | 3,801
atypical teratoid / rhabdoid tumor 19 | 5,112
lung adenocarcinoma 19 | 2,716
pancreatic cancer 19 | 2,398
intraductal papillary-mucinous carcinoma (IPMC) 18 | 2,989
non-small cell lung cancer 18 | 2,890
group 3 medulloblastoma 17 | 4,104
invasive ductal carcinoma 17 | 2,951
oligodendroglioma 17 | 2,850
Prostatic Neoplasms 15 | 495
ulcerative colitis 15 | 1,819
Astrocytoma, Pilocytic 14 | 3,081
tuberculosis 14 | 2,010
active Crohn's disease 13 | 922
ductal carcinoma in situ 13 | 1,745
malignant mesothelioma 13 | 3,232
pituitary cancer 13 | 1,972
astrocytic glioma 12 | 2,597
cystic fibrosis 12 | 1,696
Chemical and Drug Induced Liver Injury 11 | 195
adrenocortical carcinoma 11 | 1,428
esophageal adenocarcinoma 11 | 737
primitive neuroectodermal tumor 11 | 3,035
Liver Cirrhosis, Experimental 10 | 769
Pick disease 10 | 1,894
cutaneous lupus erythematosus 10 | 1,057
Autosomal recessive predisposition 9 | 1,442
Liver disease 9 | 237
Melanoma 9 | 711
Schizophrenia 9 | 1,160
breast carcinoma 9 | 1,638
Hypertension 8 | 396
astrocytoma 8 | 1,146
subependymal giant cell astrocytoma 8 | 2,287
Endometriosis 7 | 540
Rheumatoid arthritis 7 | 1,191
chronic rhinosinusitis 7 | 512
colon cancer 7 | 1,478
non diabetic and post-ischemic heart failure 7 | 200
Breast Neoplasms 6 | 445
Cholestasis 6 | 155
Epilepsy 6 | 792
Mammary Neoplasms 6 | 425
Multiple myeloma 6 | 1,332
Obesity 6 | 678
Pain agnosia 6 | 104
adrenocortical adenoma 6 | 131
aldosterone-producing adenoma 6 | 665
diabetes mellitus 6 | 1,728
nasopharyngeal carcinoma 6 | 1,058
non primary Sjogren syndrome sicca 6 | 891
primary pancreatic ductal adenocarcinoma 6 | 1,109
Adenocarcinoma 5 | 122
Alcoholic Intoxication, Chronic 5 | 289
Alzheimer's disease 5 | 658
Cerebrovascular disease 5 | 238
Coronary artery disease 5 | 268
Depressive disorder 5 | 409
Drug-Related Side Effects and Adverse Reactions 5 | 62
Kidney cancer 5 | 2,613
Lung Neoplasms 5 | 232
Major Depressive Disorder 5 | 301
Unipolar Depression 5 | 250
head and neck cancer 5 | 271
juvenile dermatomyositis 5 | 1,187
medulloblastoma 5 | 720
mucosa-associated lymphoid tissue lymphoma 5 | 484
periodontitis 5 | 293
Atopic dermatitis 4 | 952
Atrial Fibrillation 4 | 124
Diarrhea 4 | 253
Hepatomegaly 4 | 285
Hypertensive disease 4 | 292
Malaria 4 | 160
Mental Depression 4 | 333
Precursor Cell Lymphoblastic Leukemia Lymphoma 4 | 43
Precursor Cell Lymphoblastic Leukemia-Lymphoma 4 | 49
Prostate cancer 4 | 175
fibroadenoma 4 | 559
gastric carcinoma 4 | 807
hepatocellular carcinoma 4 | 547
nephrosclerosis 4 | 333
pediatric high grade glioma 4 | 1,064
spina bifida 4 | 1,074
substance-related disorder 4 | 162

Tissue

Liver and Pancreas 82 | 16,750
Female tissues 81 | 17,400
Digestive Tract 80 | 17,369
Endocrine System 80 | 18,159
Male tissues 77 | 17,142
Skin and soft tissues 77 | 17,230
Urinary Tract 76 | 16,678
Respiratory system 71 | 16,393
Blood and immune system 70 | 16,909
Nervous System 64 | 16,725
Cardiovascular System 53 | 15,192

Target Family

Enzyme 52 | 4,145
Non-IDG 33 | 12,091
Transporter 1 | 473

GO Component

organelle membrane 86 | 86
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Signal peptidase complex subunit 1 SPCS1 Tdark Enzyme -0.80900 6.46 44
Cholesterol 24-hydroxylase CYP46A1 Tbio Enzyme -1.84856 68.6 197
UDP-glucuronosyltransferase 2B7 UGT2B7 Tchem Enzyme -2.31570 219.0 131
Leucine-rich repeat transmembrane protein FLRT2 FLRT2 Tbio Non-IDG -1.09240 12.6 50
Cytochrome P450 26A1 CYP26A1 Tchem Enzyme -2.44772 290.1 197
F-box only protein 2 FBXO2 Tbio Non-IDG -1.36281 26.8 157
Cytochrome P450 4Z1 CYP4Z1 Tbio Non-IDG -0.68998 9.87 74
Phylloquinone omega-hydroxylase CYP4F11 CYP4F11 Tbio Enzyme -0.71213 6.60 96
Delta(14)-sterol reductase TM7SF2 Tbio Enzyme -1.10571 12.4 88
Cytochrome P450 4A11 CYP4A11 Tbio Non-IDG -1.97180 93.7 142