Development Level

Tbio 9 | 11,445
Tchem 1 | 1,598
Tdark 1 | 6,588

IMPC Phenotype

preweaning lethality, complete... 2 | 979
abnormal embryo size 1 | 220
abnormal forebrain morphology 1 | 10
abnormal neural tube closure 1 | 46
decreased circulating glycerol... 1 | 16
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged lymph nodes 1 | 37
increased circulating aspartat... 1 | 15
increased circulating bilirubi... 1 | 16
increased circulating chloride... 1 | 41
increased circulating free fat... 1 | 20
increased circulating glycerol... 1 | 9
increased circulating potassiu... 1 | 29
increased circulating sodium l... 1 | 71
preweaning lethality, incomple... 1 | 499
small adrenal glands 1 | 16
small spleen 1 | 19

Disease

ovarian cancer 10 | 8,520
glioblastoma 8 | 5,792
osteosarcoma 8 | 7,950
Carcinoma 5 | 11,493
Multiple myeloma 5 | 1,332
atypical teratoid / rhabdoid tumor 5 | 5,112
ependymoma 5 | 4,679
astrocytoma 4 | 1,146
group 3 medulloblastoma 4 | 4,104
lung adenocarcinoma 4 | 2,716
lung cancer 4 | 4,740
medulloblastoma, large-cell 4 | 6,241
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
Astrocytoma, Pilocytic 3 | 3,081
Autosomal recessive predisposition 3 | 1,442
Breast cancer 3 | 3,578
Congenital disorder of glycosylation 3 | 54
adult high grade glioma 3 | 3,801
diabetes mellitus 3 | 1,728
subependymal giant cell astrocytoma 3 | 2,287
Attention deficit hyperactivity disorder 2 | 278
Cognitive delay 2 | 608
Dull intelligence 2 | 645
Failure to gain weight 2 | 365
Global developmental delay 2 | 608
Intellectual disability 2 | 1,016
Low intelligence 2 | 645
Mental Retardation 2 | 645
Mental and motor retardation 2 | 608
Mental deficiency 2 | 645
Muscle hypotonia 2 | 571
Pediatric failure to thrive 2 | 365
Pick disease 2 | 1,894
Poor school performance 2 | 645
Prostatic Neoplasms 2 | 495
Schizophrenia 2 | 1,160
Waldenstrons macroglobulinemia 2 | 765
acute myeloid leukemia 2 | 783
breast carcinoma 2 | 1,638
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
juvenile dermatomyositis 2 | 1,187
non-small cell lung cancer 2 | 2,890
oligodendroglioma 2 | 2,850
pancreatic cancer 2 | 2,398
pancreatic carcinoma 2 | 562
pediatric high grade glioma 2 | 1,064
Abnormal visual pursuit 1 | 14
Acquired immunodeficiency syndrome 1 | 197
Alzheimer's disease 1 | 658
Asthma 1 | 385
Atrophy of cerebellum 1 | 103
Botulism 1 | 24
Cerebellar degeneration 1 | 103
Chondrodysplasia punctata 1 | 41
Constipation 1 | 181
Cryptogenic organizing pneumonia 1 | 3
Decreased liver function 1 | 24
Desquamative interstitial pneumonia 1 | 4
Duchenne muscular dystrophy 1 | 601
Dyschezia 1 | 135
Epilepsy 1 | 792
Gastroesophageal reflux disease 1 | 110
Gaucher disease type 3 1 | 67
Generalized hypotonia 1 | 37
Genital herpes 1 | 10
Gout 1 | 106
Heartburn 1 | 78
Hypoplasia of scrotum 1 | 24
Impaired smooth pursuit 1 | 14
Infantile onset 1 | 238
Infratentorial atrophy 1 | 103
Isoelectric focusing of serum transferrin consistent with CDG type I 1 | 10
Kidney cancer 1 | 2,613
Liver Cirrhosis, Experimental 1 | 769
Liver Dysfunction 1 | 99
Liver dysfunction, mild 1 | 24
Lymphopenia 1 | 67
Multiple Sclerosis 1 | 540
Parkinson's disease 1 | 392
Pollen allergy 1 | 6
Prenatal onset 1 | 139
Seizures 1 | 596
Strabismus 1 | 270
Thyroid adenoma 1 | 10
acute quadriplegic myopathy 1 | 1,158
aldosterone-producing adenoma 1 | 665
astrocytic glioma 1 | 2,597
cystic fibrosis 1 | 1,696
dermatomyositis 1 | 966
esophageal adenocarcinoma 1 | 737
glioblastoma multiforme 1 | 142
interstitial cystitis 1 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 1 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 1 | 2,989
invasive ductal carcinoma 1 | 2,951
lung carcinoma 1 | 2,843
pituitary cancer 1 | 1,972
primitive neuroectodermal tumor 1 | 3,035
psoriasis 1 | 6,694
ulcerative colitis 1 | 1,819

Tissue

Blood and immune system 11 | 16,909
Cardiovascular System 11 | 15,192
Digestive Tract 11 | 17,369
Endocrine System 11 | 18,159
Female tissues 11 | 17,400
Liver and Pancreas 11 | 16,750
Male tissues 11 | 17,142
Nervous System 11 | 16,725
Respiratory system 11 | 16,393
Skin and soft tissues 11 | 17,230
Urinary Tract 11 | 16,678

Target Family

Enzyme 8 | 4,145
Non-IDG 3 | 12,091

GO Component

oligosaccharyltransferase comp... 11 | 11
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

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