Development Level

Tbio 2,265 | 11,445
Tchem 355 | 1,598
Tdark 299 | 6,588
Tclin 77 | 613

Collection

RFA-RM-18-021 27 | 328
Kinase: IDG Consortium (Target... 24 | 125
Kinase: IDG Consortium (Comple... 9 | 37
GPCR: IDG Consortium (Targets) 3 | 126

IMPC Phenotype

preweaning lethality, complete... 326 | 979
preweaning lethality, incomple... 101 | 499
embryonic lethality prior to t... 92 | 278
embryonic lethality prior to o... 88 | 239
abnormal embryo size 64 | 220
abnormal behavior 60 | 298
decreased body weight 40 | 161
decreased total body fat amoun... 39 | 207
abnormal bone structure 38 | 187
enlarged heart 37 | 210
abnormal heart morphology 35 | 162
increased lean body mass 34 | 172
embryonic growth retardation 32 | 106
increased startle reflex 29 | 112
decreased lean body mass 27 | 135
male infertility 27 | 123
prenatal lethality prior to he... 27 | 87
decreased bone mineral density 26 | 126
hyperactivity 26 | 148
increased mean corpuscular vol... 26 | 92
increased bone mineral density 25 | 72
increased circulating alkaline... 25 | 122
decreased vertical activity 24 | 208
hypoactivity 24 | 132
decreased bone mineral content 23 | 151
decreased circulating glucose ... 23 | 126
increased mean corpuscular hem... 23 | 96
increased or absent threshold ... 23 | 101
cataract 22 | 92
decreased circulating choleste... 22 | 93
decreased prepulse inhibition 22 | 82
increased bone mineral content 22 | 108
decreased body length 21 | 101
increased total body fat amoun... 21 | 134
abnormal kidney morphology 20 | 65
decreased lymphocyte cell numb... 20 | 83
decreased circulating triglyce... 19 | 79
abnormal seminal vesicle morph... 18 | 114
decreased leukocyte cell numbe... 18 | 73
abnormal lens morphology 17 | 81
abnormal neural tube closure 17 | 46
decreased mean corpuscular vol... 17 | 79
decreased grip strength 16 | 116
increased circulating HDL chol... 16 | 80
abnormal coat-hair pigmentatio... 15 | 64
decreased hemoglobin content 15 | 68
abnormal retina morphology 14 | 71
corneal opacity 14 | 32
female infertility 14 | 60
increased circulating choleste... 14 | 66
short tibia 14 | 97
decreased circulating HDL chol... 13 | 68
decreased circulating LDL chol... 13 | 38
decreased circulating serum al... 13 | 82
edema 13 | 59
impaired glucose tolerance 13 | 75
increased mean platelet volume 13 | 45
abnormal embryo turning 12 | 31
abnormal eye morphology 12 | 68
abnormal gait 12 | 69
abnormal spleen morphology 12 | 55
decreased blood urea nitrogen ... 12 | 51
decreased erythrocyte cell num... 12 | 62
decreased startle reflex 12 | 75
hydrometra 12 | 53
increased grip strength 12 | 41
increased neutrophil cell numb... 12 | 46
small superior vagus ganglion 12 | 74
thrombocytopenia 12 | 56
abnormal bone mineralization 11 | 38
abnormal craniofacial morpholo... 11 | 33
decreased caudal vertebrae num... 11 | 53
decreased circulating alkaline... 11 | 46
decreased heart left ventricle... 11 | 28
decreased neutrophil cell numb... 11 | 42
increased circulating chloride... 11 | 41
increased monocyte cell number 11 | 63
tremors 11 | 39
abnormal forebrain development 10 | 20
decreased circulating alanine ... 10 | 47
decreased circulating insulin ... 10 | 76
decreased hematocrit 10 | 46
decreased mean corpuscular hem... 10 | 50
increased circulating sodium l... 10 | 71
increased hemoglobin content 10 | 45
long tibia 10 | 25
abnormal behavioral response t... 9 | 66
abnormal cornea morphology 9 | 31
abnormal skin morphology 9 | 50
decreased circulating total pr... 9 | 49
decreased mean platelet volume 9 | 25
increased body length 9 | 32
increased circulating creatini... 9 | 38
increased circulating triglyce... 9 | 42
increased mean corpuscular hem... 9 | 36
small testis 9 | 58
abnormal sleep behavior 8 | 70
anophthalmia 8 | 33
pale yolk sac 8 | 25
pallor 8 | 34

Disease

Carcinoma 1,979 | 11,493
ovarian cancer 1,832 | 8,520
osteosarcoma 1,547 | 7,950
medulloblastoma, large-cell 1,163 | 6,241
psoriasis 1,132 | 6,694
glioblastoma 1,059 | 5,792
lung cancer 1,026 | 4,740
group 3 medulloblastoma 919 | 4,104
atypical teratoid / rhabdoid tumor 896 | 5,112
Cancer 722 | 2,499
ependymoma 715 | 4,679
Breast cancer 706 | 3,578
malignant mesothelioma 699 | 3,232
primitive neuroectodermal tumor 606 | 3,035
adult high grade glioma 583 | 3,801
intraductal papillary-mucinous neoplasm (IPMN) 571 | 3,291
oligodendroglioma 523 | 2,850
non-small cell lung cancer 511 | 2,890
intraductal papillary-mucinous carcinoma (IPMC) 502 | 2,989
Kidney cancer 494 | 2,613
invasive ductal carcinoma 479 | 2,951
lung adenocarcinoma 441 | 2,716
astrocytic glioma 432 | 2,597
intraductal papillary-mucinous adenoma (IPMA) 427 | 2,955
Multiple myeloma 398 | 1,332
Pick disease 366 | 1,894
Astrocytoma, Pilocytic 361 | 3,081
pancreatic cancer 360 | 2,398
subependymal giant cell astrocytoma 358 | 2,287
pancreatic ductal adenocarcinoma liver metastasis 316 | 1,962
tuberculosis 307 | 2,010
group 4 medulloblastoma 305 | 1,855
adrenocortical carcinoma 299 | 1,428
acute quadriplegic myopathy 297 | 1,158
breast carcinoma 291 | 1,638
colon cancer 290 | 1,478
diabetes mellitus 288 | 1,728
lung carcinoma 288 | 2,843
pituitary cancer 286 | 1,972
ductal carcinoma in situ 284 | 1,745
astrocytoma 279 | 1,146
juvenile dermatomyositis 273 | 1,187
Rheumatoid arthritis 271 | 1,191
Intellectual disability 267 | 1,016
Waldenstrons macroglobulinemia 258 | 765
ulcerative colitis 256 | 1,819
interstitial cystitis 255 | 2,312
dermatomyositis 244 | 966
pediatric high grade glioma 220 | 1,064
Autosomal recessive predisposition 217 | 1,442
acute myeloid leukemia 209 | 783
Schizophrenia 191 | 1,160
cystic fibrosis 191 | 1,696
spina bifida 187 | 1,074
nasopharyngeal carcinoma 186 | 1,058
primary pancreatic ductal adenocarcinoma 177 | 1,109
Dull intelligence 169 | 645
Low intelligence 169 | 645
Mental Retardation 169 | 645
Mental deficiency 169 | 645
Poor school performance 169 | 645
Breast Neoplasms 160 | 445
Cognitive delay 159 | 608
Global developmental delay 159 | 608
Mental and motor retardation 159 | 608
Short stature 157 | 531
non primary Sjogren syndrome sicca 155 | 891
Mammary Neoplasms 152 | 425
Atopic dermatitis 147 | 952
medulloblastoma 145 | 720
progressive supranuclear palsy 143 | 676
cutaneous lupus erythematosus 142 | 1,057
Endometriosis 141 | 540
aldosterone-producing adenoma 139 | 665
primary Sjogren syndrome 137 | 735
Small head 131 | 374
Epilepsy 126 | 792
active Crohn's disease 125 | 922
hepatocellular carcinoma 122 | 547
Obesity 120 | 678
gastric carcinoma 116 | 807
Alzheimer's disease 115 | 658
Muscle hypotonia 114 | 571
esophageal adenocarcinoma 109 | 737
Liver Cirrhosis, Experimental 108 | 769
Prostatic Neoplasms 108 | 495
Bipolar Disorder 107 | 666
Seizures 107 | 596
Amyotrophic lateral sclerosis 106 | 451
Cryptorchidism 103 | 296
tuberculosis and treatment for 6 months 102 | 409
Melanoma 99 | 711
pancreatic carcinoma 99 | 562
Liver cancer 98 | 604
active ulcerative colitis 98 | 764
Stomach Neoplasms 94 | 300
gastric cancer 93 | 459
Hypoplastic mandible condyle 89 | 275
Mandibular hypoplasia 89 | 275
Micrognathism 89 | 275

Tissue

Endocrine System 2,982 | 18,159
Digestive Tract 2,974 | 17,369
Female tissues 2,966 | 17,400
Male tissues 2,963 | 17,142
Skin and soft tissues 2,962 | 17,230
Blood and immune system 2,947 | 16,909
Urinary Tract 2,943 | 16,678
Liver and Pancreas 2,940 | 16,750
Respiratory system 2,929 | 16,393
Nervous System 2,927 | 16,725
Cardiovascular System 2,867 | 15,192

Target Family

Non-IDG 1,511 | 12,091
Enzyme 644 | 4,145
Transcription Factor 424 | 1,400
Epigenetic 162 | 242
Kinase 153 | 634
Nuclear Receptor 47 | 48
TF/Epigenetic 24 | 38
Transporter 18 | 473
GPCR 8 | 408
Ion Channel 5 | 344

GO Component

nucleoplasm 2,996 | 2,996
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Zinc finger protein 175 ZNF175 Tbio Transcription Factor -0.86533 8.35 88
Probable global transcription activator SNF2L1 SMARCA1 Tbio Non-IDG -2.20560 145.6 116
40S ribosomal protein S19 RPS19 Tbio Non-IDG -3.14746 1380.8 267
Pre-mRNA-splicing factor CWC22 homolog CWC22 Tbio Non-IDG -3.08456 1172.8 103
Homeobox protein MSX-1 MSX1 Tbio Transcription Factor -2.59245 390.1 298
Heterogeneous nuclear ribonucleoprotein H3 HNRNPH3 Tbio Non-IDG -1.80776 63.4 80
Speedy protein A SPDYA Tbio Non-IDG -1.58097 42.8 145
Metastasis-associated protein MTA3 MTA3 Tbio Transcription Factor -1.36174 24.5 204
Cell division cycle protein 23 homolog CDC23 Tbio Non-IDG -1.50528 30.4 191
RNA polymerase II subunit A C-terminal domain phosphatase CTDP1 Tbio Enzyme -1.88697 80.7 113