Development Level

Tbio 575 | 10,625
Tdark 153 | 7,003
Tchem 76 | 1,890
Tclin 11 | 602

Collection

Eligible Kinase Proteins 3 | 134
Eligible non-olfactory GPCR Proteins 1 | 143

IMPC Term

preweaning lethality, complete... 52 | 633
embryonic lethality prior to o... 17 | 148
embryonic lethality prior to t... 16 | 187
abnormal behavior 12 | 226
decreased lean body mass 10 | 195
preweaning lethality, incomple... 10 | 260
abnormal embryo size 9 | 112
decreased body length 9 | 108
decreased body weight 9 | 174
abnormal retina morphology 7 | 100
decreased bone mineral content 7 | 157
decreased circulating glucose ... 7 | 121
hyperactivity 7 | 108
increased fasted circulating g... 7 | 68
abnormal coat/hair pigmentatio... 6 | 54
decreased bone mineral density 6 | 126
decreased circulating HDL chol... 6 | 77
decreased circulating choleste... 6 | 85
decreased lumbar vertebrae num... 6 | 62
increased circulating alkaline... 6 | 119
increased lean body mass 6 | 107
increased sacral vertebrae num... 6 | 62
prenatal lethality prior to he... 6 | 64
abnormal bone mineralization 5 | 55
abnormal bone structure 5 | 131
decreased circulating alanine ... 5 | 53
decreased fasted circulating g... 5 | 49
decreased total body fat amoun... 5 | 186
enlarged heart 5 | 111
increased circulating chloride... 5 | 43
abnormal heart morphology 4 | 51
abnormal lens morphology 4 | 73
abnormal limb bud morphology 4 | 15
decreased circulating chloride... 4 | 32
decreased circulating serum al... 4 | 79
decreased mean corpuscular vol... 4 | 50
decreased prepulse inhibition 4 | 52
decreased rib number 4 | 59
increased bone mineral content 4 | 92
increased circulating HDL chol... 4 | 63
increased mean corpuscular hem... 4 | 93
increased mean corpuscular vol... 4 | 91
increased or absent threshold ... 4 | 128
increased startle reflex 4 | 38
polydactyly 4 | 22
short tibia 4 | 82
abnormal neural tube closure 3 | 37
abnormal rib morphology 3 | 28
abnormal spleen morphology 3 | 36
decreased NK T cell number 3 | 28
decreased caudal vertebrae num... 3 | 49
decreased circulating aspartat... 3 | 27
decreased circulating iron lev... 3 | 25
decreased erythrocyte cell num... 3 | 43
decreased grip strength 3 | 123
decreased heart weight 3 | 44
decreased hemoglobin content 3 | 53
decreased neutrophil cell numb... 3 | 37
decreased startle reflex 3 | 48
hypoactivity 3 | 89
increased blood urea nitrogen ... 3 | 44
increased body weight 3 | 42
increased circulating LDL chol... 3 | 15
increased circulating sodium l... 3 | 71
increased grip strength 3 | 83
increased rib number 3 | 41
male infertility 3 | 62
vertebral transformation 3 | 12
abnormal body wall morphology 2 | 7
abnormal cornea morphology 2 | 24
abnormal epididymis morphology 2 | 31
abnormal kidney morphology 2 | 30
abnormal locomotor activation 2 | 26
abnormal retinal inner nuclear... 2 | 5
abnormal retinal pigmentation 2 | 61
abnormal sleep behavior 2 | 63
abnormal snout morphology 2 | 18
abnormal thoracic vertebrae mo... 2 | 16
abnormal tooth morphology 2 | 24
abnormal vocalization 2 | 21
cardiovascular system phenotyp... 2 | 35
corneal opacity 2 | 25
decreased Ly6C high monocyte n... 2 | 18
decreased blood urea nitrogen ... 2 | 31
decreased circulating LDL chol... 2 | 37
decreased circulating creatini... 2 | 31
decreased circulating triglyce... 2 | 83
decreased eosinophil cell numb... 2 | 41
decreased hematocrit 2 | 25
enlarged lymph nodes 2 | 27
hemorrhage 2 | 12
hydrops fetalis 2 | 22
impaired glucose tolerance 2 | 52
increased CD4-positive, CD25-p... 2 | 18
increased bone mineral density 2 | 52
increased circulating glucose ... 2 | 16
increased circulating glycerol... 2 | 11
increased circulating triglyce... 2 | 24
increased hemoglobin content 2 | 45
small testis 2 | 37

Disease

ovarian cancer 457 | 8,484
osteosarcoma 395 | 7,933
medulloblastoma, large-cell 315 | 6,234
lung cancer 282 | 4,466
psoriasis 282 | 6,685
glioblastoma 254 | 5,572
atypical teratoid / rhabdoid tumor 189 | 4,369
malignant mesothelioma 157 | 3,162
intraductal papillary-mucinous neoplasm (IPMN) 155 | 3,289
Cancer 149 | 2,346
group 3 medulloblastoma 148 | 2,254
Breast cancer 141 | 3,094
primitive neuroectodermal tumor 139 | 3,031
pediatric high grade glioma 133 | 2,712
Multiple myeloma 125 | 1,327
oligodendroglioma 120 | 2,849
invasive ductal carcinoma 119 | 2,950
lung adenocarcinoma 119 | 2,713
ependymoma 116 | 2,514
intraductal papillary-mucinous carcinoma (IPMC) 116 | 2,988
intraductal papillary-mucinous adenoma (IPMA) 114 | 2,956
non-small cell lung cancer 114 | 2,798
pilocytic astrocytoma 105 | 3,086
subependymal giant cell astrocytoma 100 | 2,287
Carcinoma 95 | 2,147
colon cancer 95 | 1,475
acute quadriplegic myopathy 94 | 1,157
astrocytic glioma 90 | 2,241
pancreatic cancer 89 | 2,300
Waldenstrons macroglobulinemia 84 | 765
diabetes mellitus 84 | 1,663
sonic hedgehog group medulloblastoma 81 | 1,482
lung carcinoma 79 | 2,844
Pick disease 78 | 1,893
astrocytoma 77 | 1,493
group 4 medulloblastoma 71 | 1,875
adult high grade glioma 70 | 2,148
dermatomyositis 70 | 933
pituitary cancer 70 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 69 | 1,795
juvenile dermatomyositis 68 | 1,189
ductal carcinoma in situ 63 | 1,745
medulloblastoma 63 | 1,524
ulcerative colitis 63 | 2,087
cystic fibrosis 59 | 1,665
breast carcinoma 58 | 1,614
adrenocortical carcinoma 57 | 1,427
posterior fossa group A ependymoma 57 | 1,511
Rheumatoid Arthritis 55 | 1,160
atypical teratoid/rhabdoid tumor 55 | 1,095
acute myeloid leukemia 51 | 780
tuberculosis 51 | 1,557
cutaneous lupus erythematosus 50 | 1,056
interstitial cystitis 49 | 2,299
spina bifida 49 | 1,064
nasopharyngeal carcinoma 48 | 1,056
primary pancreatic ductal adenocarcinoma 48 | 1,271
Intellectual disability 47 | 573
non primary Sjogren syndrome sicca 46 | 840
tuberculosis and treatment for 6 months 45 | 686
posterior fossa group B ependymoma 35 | 1,530
Prostatic Neoplasms 34 | 471
Alzheimer's disease 32 | 644
Mammary Neoplasms 31 | 410
progressive supranuclear palsy 31 | 674
primary Sjogren syndrome 29 | 789
Amyotrophic Lateral Sclerosis 28 | 431
Endometriosis 28 | 535
Stomach Neoplasms 27 | 282
esophageal adenocarcinoma 27 | 737
hepatocellular carcinoma 27 | 532
IGA Glomerulonephritis 26 | 454
active Crohn's disease 26 | 918
gastric carcinoma 26 | 832
Atopic dermatitis 25 | 944
Down syndrome 25 | 548
Neurodegenerative disease 25 | 383
inflammatory breast cancer 25 | 404
pancreatic carcinoma 25 | 567
aldosterone-producing adenoma 23 | 664
Duchenne muscular dystrophy 22 | 602
autosomal dominant Emery-Dreifuss muscular dystrophy 21 | 499
Obesity 20 | 616
Disease Progression 19 | 125
Microcephaly 19 | 149
Parkinson's disease 19 | 364
gastric cancer 18 | 430
Liver carcinoma 17 | 217
Polycystic Ovary Syndrome 17 | 332
Schizophrenia 16 | 501
chronic rhinosinusitis 16 | 512
mucosa-associated lymphoid tissue lymphoma 16 | 480
Anemia 15 | 252
Cockayne syndrome 15 | 54
Peripheral Neuropathy 15 | 303
interstitial lung disease 15 | 291
Vascular disease 14 | 281
fibroadenoma 14 | 557
Heart disease 13 | 279
Multiple Sclerosis 13 | 498

Tissue

Female tissues 798 | 18,647
Nervous System 797 | 18,561
Digestive Tract 795 | 18,473
Male tissues 795 | 17,969
Endocrine System 793 | 18,512
Blood and immune system 792 | 17,995
Liver and Pancreas 792 | 18,136
Urinary Tract 789 | 18,444
Cardiovascular System 788 | 17,958
Skin and soft tissues 785 | 18,115
Respiratory system 783 | 17,484

Target Family

Non-IDG 499 | 11,971
Enzyme 187 | 4,146
Transcription Factor 61 | 1,400
Epigenetic 28 | 242
Kinase 25 | 634
TF/Epigenetic 5 | 38
Transporter 5 | 473
Ion Channel 2 | 341
Nuclear Receptor 2 | 48
GPCR 1 | 406

GO Component

nucleolus 815 | 815
nucleus 5,107 | 5,107
cytoplasm 4,985 | 4,985
plasma membrane 4,118 | 4,118
integral component of membrane 3,679 | 3,679
cytosol 3,265 | 3,265
extracellular exosome 2,758 | 2,758
nucleoplasm 2,717 | 2,717
membrane 1,906 | 1,906
extracellular region 1,493 | 1,493
integral component of plasma m... 1,406 | 1,406
extracellular space 1,304 | 1,304
mitochondrion 1,231 | 1,231
Golgi apparatus 864 | 864
endoplasmic reticulum 859 | 859
endoplasmic reticulum membrane 848 | 848
Golgi membrane 659 | 659
perinuclear region of cytoplas... 611 | 611
cell surface 594 | 594
intracellular 548 | 548
intracellular membrane-bounded... 537 | 537
cell junction 451 | 451
mitochondrial inner membrane 425 | 425
centrosome 409 | 409
focal adhesion 383 | 383
protein complex 355 | 355
cytoskeleton 343 | 343
dendrite 329 | 329
mitochondrial matrix 322 | 322
cell-cell adherens junction 307 | 307
neuronal cell body 303 | 303
microtubule 294 | 294
lysosomal membrane 278 | 278
apical plasma membrane 277 | 277
proteinaceous extracellular ma... 244 | 244
neuron projection 229 | 229
nuclear membrane 218 | 218
early endosome 217 | 217
axon 214 | 214
lysosome 210 | 210
endosome 208 | 208
actin cytoskeleton 205 | 205
external side of plasma membra... 205 | 205
postsynaptic membrane 204 | 204
extracellular matrix 198 | 198
nuclear speck 197 | 197
membrane raft 196 | 196
endoplasmic reticulum lumen 192 | 192
transcription factor complex 184 | 184
endosome membrane 182 | 182
early endosome membrane 180 | 180
basolateral plasma membrane 174 | 174
nuclear chromatin 169 | 169
synapse 166 | 166
cell-cell junction 161 | 161
nuclear envelope 156 | 156
lamellipodium 153 | 153
mitochondrial outer membrane 148 | 148
blood microparticle 147 | 147
myelin sheath 144 | 144
postsynaptic density 144 | 144
cytoplasmic vesicle 143 | 143
microtubule organizing center 137 | 137
cytoplasmic, membrane-bounded ... 132 | 132
ER to Golgi transport vesicle ... 131 | 131
microtubule cytoskeleton 127 | 127
receptor complex 127 | 127
phagocytic vesicle membrane 126 | 126
cytoplasmic vesicle membrane 125 | 125
midbody 125 | 125
trans-Golgi network 124 | 124
cell cortex 119 | 119
cilium 118 | 118
late endosome 116 | 116
spindle 116 | 116
intracellular ribonucleoprotei... 114 | 114
vesicle 112 | 112
Z disc 110 | 110
bicellular tight junction 110 | 110
anchored component of membrane 109 | 109
growth cone 109 | 109
integral component of lumenal ... 108 | 108
late endosome membrane 107 | 107
endomembrane system 106 | 106
centriole 105 | 105
recycling endosome 104 | 104
spindle pole 104 | 104
perikaryon 103 | 103
integral component of endoplas... 101 | 101
intermediate filament 101 | 101
melanosome 101 | 101
chromosome 100 | 100
dendritic spine 99 | 99
ubiquitin ligase complex 99 | 99
peroxisome 98 | 98
nuclear matrix 97 | 97
PML body 94 | 94
Golgi lumen 93 | 93
keratin filament 93 | 93
trans-Golgi network membrane 92 | 92

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Cyclin-dependent kinase 8 CDK8 Tchem Kinase -1.96301 102.7 307
Angiogenin ANG Tbio Enzyme -2.89794 796.0 203
E3 ubiquitin-protein ligase Mdm2 MDM2 Tchem Enzyme -3.38438 2174.7 1062
Interleukin enhancer-binding factor 2 ILF2 Tbio Non-IDG -1.51960 36.4 249
Interleukin enhancer-binding factor 3 ILF3 Tbio Non-IDG -2.09543 135.8 239
Nucleolar GTP-binding protein 1 GTPBP4 Tbio Non-IDG -3.21425 1443.3 95
A-kinase anchor protein 8 AKAP8 Tbio Enzyme -1.32097 22.6 240
U3 small nucleolar RNA-interacting protein 2 RRP9 Tbio Non-IDG -0.95790 8.59 56
Zinc finger BED domain-containing protein 6 ZBED6 Tdark Non-IDG -0.79472 9.28 0
60S ribosomal protein L7a RPL7A Tbio Non-IDG -1.66015 45.9 60