Development Level

Tbio 15 | 11,651
Tchem 5 | 1,388
Tclin 2 | 612
Tdark 1 | 6,593

IMPC Phenotype

preweaning lethality, complete... 3 | 979
decreased vertical activity 2 | 208
abnormal behavioral response t... 1 | 66
abnormal bone structure 1 | 187
abnormal lens morphology 1 | 81
abnormal limb morphology 1 | 13
abnormal sleep behavior 1 | 70
abnormal tail morphology 1 | 25
cataract 1 | 92
cyanosis 1 | 7
decreased basophil cell number 1 | 16
decreased body length 1 | 101
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating lipase l... 1 | 3
decreased heart weight 1 | 27
decreased hemoglobin content 1 | 68
decreased lean body mass 1 | 135
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular hem... 1 | 31
edema 1 | 59
hemorrhage 1 | 23
hypoactivity 1 | 132
increased mean corpuscular hem... 1 | 96
increased total body fat amoun... 1 | 134
preweaning lethality, incomple... 1 | 499
respiratory system phenotype 1 | 2
thrombocytopenia 1 | 56

Disease

Carcinoma 14 | 11,493
ovarian cancer 14 | 8,520
psoriasis 10 | 6,694
ependymoma 8 | 4,679
medulloblastoma, large-cell 8 | 6,241
Autosomal recessive predisposition 7 | 1,442
glioblastoma 7 | 5,792
invasive ductal carcinoma 7 | 2,951
lung cancer 7 | 4,740
malignant mesothelioma 7 | 3,232
osteosarcoma 7 | 7,950
Astrocytoma, Pilocytic 6 | 3,081
Breast cancer 6 | 3,578
atypical teratoid / rhabdoid tumor 6 | 5,112
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
lung adenocarcinoma 6 | 2,716
oligodendroglioma 6 | 2,850
subependymal giant cell astrocytoma 6 | 2,287
Muscle hypotonia 5 | 571
astrocytic glioma 5 | 2,597
breast carcinoma 5 | 1,638
ductal carcinoma in situ 5 | 1,745
group 3 medulloblastoma 5 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
Alzheimer's disease 4 | 658
Amyotrophic lateral sclerosis 4 | 451
Childhood onset 4 | 38
Dysarthria 4 | 192
Kidney cancer 4 | 2,613
Liver cancer 4 | 604
Neurodegenerative disease 4 | 414
Pick disease 4 | 1,894
Seizures 4 | 596
adult high grade glioma 4 | 3,801
colon cancer 4 | 1,478
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
non-small cell lung cancer 4 | 2,890
pancreatic cancer 4 | 2,398
Atopic dermatitis 3 | 952
Autistic Disorder 3 | 364
Cataract 3 | 297
Cognitive delay 3 | 608
Creatine phosphokinase serum increased 3 | 110
Deglutition Disorders 3 | 132
Elevated creatine kinase 3 | 110
Emery-Dreifuss muscular dystrophy 3 | 23
Epilepsy 3 | 792
Global developmental delay 3 | 608
Intellectual disability 3 | 1,016
Lens Opacities 3 | 231
Mental and motor retardation 3 | 608
Muscular Dystrophy, Emery-Dreifuss 3 | 5
Muscular dystrophy 3 | 75
Nystagmus 3 | 317
Slow progression 3 | 89
adrenocortical carcinoma 3 | 1,428
aldosterone-producing adenoma 3 | 665
primitive neuroectodermal tumor 3 | 3,035
progressive supranuclear palsy 3 | 676
tuberculosis 3 | 2,010
ulcerative colitis 3 | 1,819
Aggressive behavior 2 | 75
Aggressive reaction 2 | 75
Alcoholic Intoxication, Chronic 2 | 289
Anteverted nostril 2 | 191
Babinski Reflex 2 | 100
Broad flat nasal bridge 2 | 236
Cancer 2 | 2,499
Cerebral atrophy 2 | 178
Cocaine-Related Disorders 2 | 92
Dementia 2 | 175
Depressive disorder 2 | 409
Down syndrome 2 | 499
Dystonia 2 | 164
Dystonic disease 2 | 106
Electromyogram abnormal 2 | 49
Failure to gain weight 2 | 365
Gliosis 2 | 56
Highly variable clinical phenotype 2 | 150
Highly variable phenotype and severity 2 | 150
Highly variable phenotype, even within families 2 | 150
Muscle Hypertonia 2 | 88
Muscle biopsy shows dystrophic changes 2 | 39
Nasal bridge wide 2 | 236
Pediatric failure to thrive 2 | 365
Phenotypic variability 2 | 150
Physical aggression 2 | 76
Progressive disorder 2 | 142
Strabismus 2 | 270
Toxic encephalopathy 2 | 141
active ulcerative colitis 2 | 764
acute quadriplegic myopathy 2 | 1,158
astrocytoma 2 | 1,146
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
juvenile dermatomyositis 2 | 1,187
pancreatic carcinoma 2 | 562
pediatric high grade glioma 2 | 1,064
pituitary cancer 2 | 1,972
urothelial carcinoma 2 | 318

Tissue

Endocrine System 23 | 18,159
Blood and immune system 21 | 16,909
Digestive Tract 21 | 17,369
Female tissues 21 | 17,400
Liver and Pancreas 21 | 16,750
Male tissues 21 | 17,142
Skin and soft tissues 21 | 17,230
Urinary Tract 21 | 16,678
Cardiovascular System 20 | 15,192
Nervous System 20 | 16,725
Respiratory system 20 | 16,393

Target Family

Non-IDG 14 | 12,091
Enzyme 4 | 4,145
Kinase 3 | 634
GPCR 1 | 408
Ion Channel 1 | 344

GO Component

nuclear outer membrane 23 | 23
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Protein KASH5 CCDC155 Tdark Non-IDG -0.58600 3.79 39
Alpha-synuclein SNCA Tchem Non-IDG -3.63937 4224.9 1813
Nesprin-1 SYNE1 Tbio Non-IDG -2.28105 171.4 65
Presenilin-1 PSEN1 Tchem Enzyme -3.53128 3394.7 677
Nuclear transport factor 2 NUTF2 Tbio Non-IDG -2.62403 421.6 97
All-trans-retinol 13,14-reductase RETSAT Tbio Enzyme -0.76918 7.46 14
Nesprin-2 SYNE2 Tbio Non-IDG -2.62747 380.6 39
Sigma non-opioid intracellular receptor 1 SIGMAR1 Tclin Non-IDG -2.28907 210.0 143
Leucine-rich PPR motif-containing protein, mitochondrial LRPPRC Tbio Non-IDG -1.67434 54.1 80
Transmembrane protein 109 TMEM109 Tbio Non-IDG -0.59060 3.93 38