Development Level

Tbio 157 | 10,625
Tdark 32 | 7,003
Tchem 20 | 1,890
Tclin 9 | 602

Collection

GPCR: IDG Consortium (Targets) 1 | 128
Ion Channel: IDG Consortium (Targets) 1 | 102

IMPC Phenotype

preweaning lethality, complete... 11 | 633
abnormal behavior 4 | 226
decreased body weight 4 | 174
increased circulating alkaline... 4 | 119
increased mean corpuscular hem... 4 | 93
preweaning lethality, incomple... 4 | 260
abnormal bone structure 3 | 131
decreased bone mineral content 3 | 157
decreased circulating alkaline... 3 | 41
decreased grip strength 3 | 123
decreased lean body mass 3 | 195
impaired glucose tolerance 3 | 52
increased lean body mass 3 | 107
small thymus 3 | 11
tremors 3 | 34
abnormal heart left ventricle ... 2 | 20
abnormal lens morphology 2 | 73
abnormal locomotor activation 2 | 26
abnormal motor coordination- b... 2 | 4
abnormal snout morphology 2 | 18
decreased basophil cell number 2 | 11
decreased circulating HDL chol... 2 | 77
decreased circulating choleste... 2 | 85
decreased circulating glucose ... 2 | 121
decreased fasted circulating g... 2 | 49
decreased leukocyte cell numbe... 2 | 54
decreased pulmonary respirator... 2 | 4
enlarged stomach 2 | 2
hydrops fetalis 2 | 22
hypoactivity 2 | 89
immune system phenotype 2 | 17
lethargy 2 | 5
short tibia 2 | 82
abnormal behavioral response t... 1 | 52
abnormal bone mineralization 1 | 55
abnormal coping response 1 | 12
abnormal cornea morphology 1 | 24
abnormal embryo size 1 | 112
abnormal eye morphology 1 | 38
abnormal head morphology 1 | 10
abnormal limb bud morphology 1 | 15
abnormal limb morphology 1 | 7
abnormal retina morphology 1 | 100
abnormal retinal pigmentation 1 | 61
abnormal skin morphology 1 | 23
abnormal sleep behavior 1 | 63
abnormal tail morphology 1 | 17
cataract 1 | 26
corneal opacity 1 | 25
cyanosis 1 | 6
decreased B cell number 1 | 30
decreased circulating aspartat... 1 | 27
decreased circulating calcium ... 1 | 33
decreased circulating glycerol... 1 | 19
decreased circulating insulin ... 1 | 75
decreased exploration in new e... 1 | 9
decreased hematocrit 1 | 25
decreased pro-B cell number 1 | 2
decreased rib number 1 | 59
decreased thoracic vertebrae n... 1 | 7
edema 1 | 11
enlarged heart 1 | 111
female infertility 1 | 34
hemorrhage 1 | 12
hyperactivity 1 | 108
impaired righting response 1 | 19
increased blood urea nitrogen ... 1 | 44
increased body weight 1 | 42
increased bone mineral content 1 | 92
increased bone mineral density 1 | 52
increased circulating creatine... 1 | 2
increased circulating potassiu... 1 | 31
increased circulating sodium l... 1 | 71
increased circulating total pr... 1 | 20
increased circulating triglyce... 1 | 24
increased heart weight 1 | 37
increased hematocrit 1 | 36
increased hemoglobin content 1 | 45
increased lactate dehydrogenas... 1 | 3
increased mean corpuscular vol... 1 | 91
increased or absent threshold ... 1 | 128
increased pro-B cell number 1 | 1
male infertility 1 | 62
microphthalmia 1 | 15
prolonged PQ interval 1 | 3
respiratory system phenotype 1 | 2

Disease

ovarian cancer 135 | 8,491
osteosarcoma 120 | 7,933
medulloblastoma, large-cell 99 | 6,234
lung cancer 88 | 4,473
glioblastoma 83 | 5,572
psoriasis 76 | 6,685
atypical teratoid / rhabdoid tumor 64 | 4,369
malignant mesothelioma 51 | 3,163
group 3 medulloblastoma 50 | 2,254
intraductal papillary-mucinous neoplasm (IPMN) 49 | 3,289
non-small cell lung cancer 48 | 2,798
Breast cancer 47 | 3,098
intraductal papillary-mucinous carcinoma (IPMC) 47 | 2,988
pediatric high grade glioma 46 | 2,712
invasive ductal carcinoma 43 | 2,950
primitive neuroectodermal tumor 43 | 3,031
oligodendroglioma 42 | 2,849
intraductal papillary-mucinous adenoma (IPMA) 40 | 2,956
Cancer 38 | 2,346
lung adenocarcinoma 37 | 2,714
ependymoma 35 | 2,514
pancreatic cancer 35 | 2,300
Carcinoma 34 | 2,147
Multiple myeloma 34 | 1,327
pilocytic astrocytoma 34 | 3,086
lung carcinoma 33 | 2,844
subependymal giant cell astrocytoma 33 | 2,287
Pick disease 31 | 1,893
colon cancer 30 | 1,475
pancreatic ductal adenocarcinoma liver metastasis 30 | 1,795
acute quadriplegic myopathy 29 | 1,157
group 4 medulloblastoma 29 | 1,875
ulcerative colitis 29 | 2,087
adult high grade glioma 28 | 2,148
dermatomyositis 27 | 966
breast carcinoma 25 | 1,614
ductal carcinoma in situ 25 | 1,745
juvenile dermatomyositis 25 | 1,189
astrocytic glioma 24 | 2,241
astrocytoma 24 | 1,493
primary pancreatic ductal adenocarcinoma 24 | 1,271
Rheumatoid Arthritis 22 | 1,170
interstitial cystitis 22 | 2,299
cystic fibrosis 21 | 1,670
medulloblastoma 21 | 1,524
pituitary cancer 21 | 1,972
tuberculosis 21 | 1,563
adrenocortical carcinoma 20 | 1,427
posterior fossa group A ependymoma 20 | 1,511
atypical teratoid/rhabdoid tumor 19 | 1,095
cutaneous lupus erythematosus 18 | 1,056
nasopharyngeal carcinoma 18 | 1,056
primary Sjogren syndrome 18 | 788
sonic hedgehog group medulloblastoma 18 | 1,482
diabetes mellitus 16 | 1,663
Waldenstrons macroglobulinemia 15 | 764
Down syndrome 14 | 548
non primary Sjogren syndrome sicca 14 | 840
Mammary Neoplasms 13 | 410
posterior fossa group B ependymoma 13 | 1,530
tuberculosis and treatment for 6 months 13 | 686
Alzheimer's disease 12 | 644
Amyotrophic Lateral Sclerosis 12 | 432
Atopic dermatitis 12 | 944
aldosterone-producing adenoma 12 | 664
gastric carcinoma 12 | 832
Duchenne muscular dystrophy 11 | 602
esophageal adenocarcinoma 11 | 737
Emery-Dreifuss muscular dystrophy 10 | 24
hereditary spastic paraplegia 10 | 313
progressive supranuclear palsy 10 | 674
sarcoidosis 10 | 368
Asthma 9 | 349
Endometriosis 9 | 535
Neurodegenerative disease 9 | 383
active Crohn's disease 9 | 918
active ulcerative colitis 9 | 477
autosomal dominant Emery-Dreifuss muscular dystrophy 9 | 499
pancreatic carcinoma 9 | 567
spina bifida 9 | 1,064
Diabetes Mellitus, Non-Insulin-Dependent 8 | 161
IGA Glomerulonephritis 8 | 454
Schizophrenia 8 | 503
acute myeloid leukemia 8 | 785
mucosa-associated lymphoid tissue lymphoma 8 | 480
Cerebrovascular disease 7 | 231
Coronary artery disease 7 | 240
Prostatic Neoplasms 7 | 471
hepatocellular carcinoma 7 | 550
Epilepsy 6 | 346
Heart disease 6 | 279
Kidney disease 6 | 397
Multiple Sclerosis 6 | 498
Stomach Neoplasms 6 | 282
Vascular disease 6 | 281
chronic rhinosinusitis 6 | 512
gastric cancer 6 | 436
inflammatory breast cancer 6 | 404
tuberculosis and treatment for 3 months 6 | 327
urothelial carcinoma 6 | 318

Tissue

Blood and immune system 217 | 17,994
Female tissues 217 | 18,646
Male tissues 217 | 17,968
Nervous System 217 | 18,560
Digestive Tract 216 | 18,472
Endocrine System 216 | 18,511
Liver and Pancreas 216 | 18,135
Cardiovascular System 215 | 17,957
Urinary Tract 215 | 18,443
Respiratory system 214 | 17,483
Skin and soft tissues 213 | 18,114

Target Family

Non-IDG 134 | 11,969
Enzyme 42 | 4,146
Transcription Factor 15 | 1,400
Kinase 10 | 634
Ion Channel 5 | 341
GPCR 4 | 408
Transporter 4 | 473
Epigenetic 3 | 242
Nuclear Receptor 1 | 48

GO Component

nuclear membrane 218 | 218
nucleus 5,106 | 5,106
cytoplasm 4,984 | 4,984
plasma membrane 4,118 | 4,118
integral component of membrane 3,679 | 3,679
cytosol 3,264 | 3,264
extracellular exosome 2,757 | 2,757
nucleoplasm 2,716 | 2,716
membrane 1,906 | 1,906
extracellular region 1,493 | 1,493
integral component of plasma m... 1,406 | 1,406
extracellular space 1,304 | 1,304
mitochondrion 1,231 | 1,231
Golgi apparatus 864 | 864
endoplasmic reticulum 859 | 859
endoplasmic reticulum membrane 848 | 848
nucleolus 815 | 815
Golgi membrane 659 | 659
perinuclear region of cytoplas... 611 | 611
cell surface 594 | 594
intracellular 548 | 548
intracellular membrane-bounded... 536 | 536
cell junction 451 | 451
mitochondrial inner membrane 425 | 425
centrosome 409 | 409
focal adhesion 383 | 383
protein complex 355 | 355
cytoskeleton 343 | 343
dendrite 329 | 329
mitochondrial matrix 322 | 322
cell-cell adherens junction 307 | 307
neuronal cell body 303 | 303
microtubule 294 | 294
lysosomal membrane 278 | 278
apical plasma membrane 277 | 277
proteinaceous extracellular ma... 244 | 244
neuron projection 229 | 229
early endosome 217 | 217
axon 214 | 214
lysosome 210 | 210
endosome 208 | 208
actin cytoskeleton 205 | 205
external side of plasma membra... 205 | 205
postsynaptic membrane 204 | 204
extracellular matrix 198 | 198
nuclear speck 197 | 197
membrane raft 196 | 196
endoplasmic reticulum lumen 192 | 192
transcription factor complex 184 | 184
endosome membrane 182 | 182
early endosome membrane 180 | 180
basolateral plasma membrane 174 | 174
nuclear chromatin 169 | 169
synapse 166 | 166
cell-cell junction 161 | 161
nuclear envelope 156 | 156
lamellipodium 153 | 153
mitochondrial outer membrane 148 | 148
blood microparticle 147 | 147
myelin sheath 144 | 144
postsynaptic density 144 | 144
cytoplasmic vesicle 143 | 143
microtubule organizing center 137 | 137
cytoplasmic, membrane-bounded ... 132 | 132
ER to Golgi transport vesicle ... 131 | 131
microtubule cytoskeleton 127 | 127
receptor complex 127 | 127
phagocytic vesicle membrane 126 | 126
cytoplasmic vesicle membrane 125 | 125
midbody 125 | 125
trans-Golgi network 124 | 124
cell cortex 119 | 119
cilium 118 | 118
late endosome 116 | 116
spindle 116 | 116
intracellular ribonucleoprotei... 114 | 114
vesicle 112 | 112
Z disc 110 | 110
bicellular tight junction 110 | 110
anchored component of membrane 109 | 109
growth cone 109 | 109
integral component of lumenal ... 108 | 108
late endosome membrane 107 | 107
endomembrane system 106 | 106
centriole 105 | 105
recycling endosome 104 | 104
spindle pole 104 | 104
perikaryon 103 | 103
integral component of endoplas... 101 | 101
intermediate filament 101 | 101
melanosome 101 | 101
chromosome 100 | 100
dendritic spine 99 | 99
ubiquitin ligase complex 99 | 99
peroxisome 98 | 98
nuclear matrix 97 | 97
PML body 94 | 94
Golgi lumen 93 | 93
keratin filament 93 | 93
trans-Golgi network membrane 92 | 92

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Aquaporin-1 AQP1 Tbio Non-IDG -3.06090 1040.5 321
GTP cyclohydrolase 1 GCH1 Tbio Enzyme -2.78255 613.4 202
Zinc finger protein RFP TRIM27 Tbio Non-IDG -1.50884 32.8 154
Cystatin-C CST3 Tbio Non-IDG -3.48935 3020.7 756
Adenylate kinase 9 AK9 Tbio Kinase -0.95667 9.15 83
Histone lysine demethylase PHF8 PHF8 Tchem Epigenetic -1.45177 33.5 70
Centrosomal protein of 131 kDa CEP131 Tbio Non-IDG -1.75708 61.0 81
Fizzy-related protein homolog FZR1 Tbio Non-IDG -1.77039 58.7 182
Erbin ERBIN Tbio Non-IDG -1.68182 53.5 111
Denticleless protein homolog DTL Tbio Non-IDG -1.60626 45.3 123