Development Level

Tbio 5 | 11,445
Tchem 3 | 1,598

IMPC Phenotype

abnormal retina morphology 1 | 71
preweaning lethality, complete... 1 | 979

Disease

osteosarcoma 7 | 7,950
Carcinoma 4 | 11,493
atypical teratoid / rhabdoid tumor 4 | 5,112
glioblastoma 4 | 5,792
oligodendroglioma 4 | 2,850
Astrocytoma, Pilocytic 3 | 3,081
Cognitive delay 3 | 608
Epilepsy 3 | 792
Global developmental delay 3 | 608
Mental and motor retardation 3 | 608
ependymoma 3 | 4,679
group 3 medulloblastoma 3 | 4,104
lung cancer 3 | 4,740
medulloblastoma, large-cell 3 | 6,241
ovarian cancer 3 | 8,520
pediatric high grade glioma 3 | 1,064
primitive neuroectodermal tumor 3 | 3,035
Alopecia 2 | 115
Autosomal recessive predisposition 2 | 1,442
Broad flat nasal bridge 2 | 236
Byzanthine arch palate 2 | 194
COPD 2 | 118
Gait abnormality 2 | 135
Growth delay 2 | 114
Growth failure 2 | 114
Growth retardation 2 | 115
Hypohidrosis 2 | 34
Hypoplastic mandible condyle 2 | 275
Large auricle 2 | 87
Large dysplastic ears 2 | 87
Large pinnae 2 | 87
Large prominent ears 2 | 87
Large protruding ears 2 | 87
Large, floppy ears 2 | 87
Macrotia 2 | 87
Mandibular hypoplasia 2 | 275
Micrognathism 2 | 275
Muscle hypotonia 2 | 571
Nasal bridge wide 2 | 236
Orbital separation excessive 2 | 244
Poor growth 2 | 114
Postnatal growth retardation 2 | 57
Seizures 2 | 596
Sensorineural Hearing Loss (disorder) 2 | 284
Short stature 2 | 531
Very poor growth 2 | 114
Weight decreased 2 | 103
acute quadriplegic myopathy 2 | 1,158
astrocytic glioma 2 | 2,597
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
lung carcinoma 2 | 2,843
subependymal giant cell astrocytoma 2 | 2,287
Absence of subcutaneous fat 1 | 3
Acute pancreatitis 1 | 10
Atrial Flutter 1 | 4
Autosomal Recessive Emery-Dreifuss Muscular Dystrophy 1 | 1
Axial muscle weakness 1 | 6
Bipartite clavicle 1 | 5
Calcification of mitral valve 1 | 2
Carcinoid tumor of lung 1 | 1
Cardiomyopathy, Familial Idiopathic 1 | 1
Congenital Foot Deformity 1 | 4
Congenital Hand Deformities 1 | 8
Double ureter 1 | 6
Familial Partial Lipodystrophy, Type 1 1 | 1
Familial Partial Lipodystrophy, Type 2 1 | 1
Familial generalized lipodystrophy 1 | 5
Foot Deformities, Congenital 1 | 4
HIV-Associated Lipodystrophy Syndrome 1 | 2
Hand Deformities, Congenital 1 | 8
Hydrops of placenta 1 | 2
Hypoplastic facial bones 1 | 4
Increased intraabdominal fat 1 | 3
Increased intramuscular fat 1 | 1
Labial pseudohypertrophy 1 | 1
Lethal restrictive dermopathy 1 | 5
Lethal tight skin contracture syndrome (disorder) 1 | 2
Lipodystrophy, Familial Partial 1 | 8
Localized scleroderma 1 | 9
Loss of subcutaneous adipose tissue in limbs 1 | 6
Loss of truncal adipose tissue 1 | 2
MUSCULAR DYSTROPHY, LIMB-GIRDLE, TYPE 1B (disorder) 1 | 1
Malouf syndrome 1 | 1
Muscular Dystrophies, Limb-Girdle 1 | 7
Najjar syndrome 1 | 1
Neoplasm of small intestine 1 | 1
Pelvic girdle weakness 1 | 7
Pelvic muscle wasting 1 | 2
Peripheral Arterial Diseases 1 | 3
Peroneal muscle weakness 1 | 1
Pili Torti 1 | 6
Pinched nasal tip 1 | 2
Progressive acroosteolysis of the clavicle 1 | 3
Prominent superficial veins 1 | 3
Proximal lower limb muscle atrophy 1 | 3
Pseudoarthrosis of clavicle 1 | 5
Renal carcinoma 1 | 1
Sinoatrial Block 1 | 1
Subcutaneous calcification 1 | 2

Tissue

Blood and immune system 8 | 16,909
Cardiovascular System 8 | 15,192
Digestive Tract 8 | 17,369
Endocrine System 8 | 18,159
Female tissues 8 | 17,400
Liver and Pancreas 8 | 16,750
Male tissues 8 | 17,142
Nervous System 8 | 16,725
Respiratory system 8 | 16,393
Skin and soft tissues 8 | 17,230
Urinary Tract 8 | 16,678

Target Family

Non-IDG 5 | 12,091
Enzyme 1 | 4,145
Epigenetic 1 | 242
Kinase 1 | 634

GO Component

nuclear lamina 8 | 8
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Nuclear prelamin A recognition factor NARF Tbio Non-IDG -1.27665 18.1 132
Peripheral plasma membrane protein CASK CASK Tchem Kinase -2.12241 130.2 227
Histone-lysine N-methyltransferase SUV39H1 SUV39H1 Tchem Epigenetic -2.27556 174.3 306
Syntaxin-1B STX1B Tbio Non-IDG -1.76579 55.3 27
Proline-rich protein 14 PRR14 Tbio Non-IDG -0.76170 6.46 60
Prelamin-A/C LMNA Tbio Non-IDG -3.03952 1089.9 1005
Biotin--protein ligase HLCS Tchem Enzyme -2.34004 223.3 86
Nucleoporin NUP53 NUP35 Tbio Non-IDG -1.18190 16.6 152