Development Level

Tbio 20 | 11,651
Tdark 18 | 6,593
Tchem 4 | 1,388
Tclin 3 | 612

IMPC Phenotype

preweaning lethality, incomple... 5 | 499
preweaning lethality, complete... 4 | 979
decreased hemoglobin content 3 | 68
abnormal heart morphology 2 | 162
abnormal sleep behavior 2 | 70
decreased hematocrit 2 | 46
decreased vertical activity 2 | 208
enlarged heart 2 | 210
increased mean corpuscular hem... 2 | 96
abnormal behavior 1 | 298
abnormal behavioral response t... 1 | 66
abnormal bone structure 1 | 187
abnormal embryo size 1 | 220
abnormal heart left ventricle ... 1 | 16
abnormal hindlimb morphology 1 | 2
abnormal lens morphology 1 | 81
abnormal limb position 1 | 3
abnormal ovary morphology 1 | 7
abnormal thymus morphology 1 | 7
cataract 1 | 92
decreased body length 1 | 101
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating alkaline... 1 | 46
decreased circulating calcium ... 1 | 36
decreased circulating free fat... 1 | 31
decreased circulating lipase l... 1 | 3
decreased erythrocyte cell num... 1 | 62
decreased heart weight 1 | 27
decreased lean body mass 1 | 135
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular hem... 1 | 31
embryonic growth retardation 1 | 106
embryonic lethality prior to t... 1 | 278
enlarged thymus 1 | 5
hyperactivity 1 | 148
increased circulating creatini... 1 | 38
increased fasted circulating g... 1 | 76
increased monocyte cell number 1 | 63
increased total body fat amoun... 1 | 134
small epididymis 1 | 3
thrombocytopenia 1 | 56

Disease

Carcinoma 29 | 11,493
ovarian cancer 22 | 8,520
medulloblastoma, large-cell 20 | 6,241
osteosarcoma 20 | 7,950
psoriasis 17 | 6,694
lung cancer 14 | 4,740
glioblastoma 13 | 5,792
intraductal papillary-mucinous carcinoma (IPMC) 12 | 2,989
atypical teratoid / rhabdoid tumor 11 | 5,112
intraductal papillary-mucinous neoplasm (IPMN) 11 | 3,291
Breast cancer 10 | 3,578
group 3 medulloblastoma 10 | 4,104
adult high grade glioma 9 | 3,801
ependymoma 8 | 4,679
malignant mesothelioma 8 | 3,232
non-small cell lung cancer 8 | 2,890
Multiple myeloma 7 | 1,332
Waldenstrons macroglobulinemia 7 | 765
cystic fibrosis 7 | 1,696
Astrocytoma, Pilocytic 6 | 3,081
Autosomal recessive predisposition 6 | 1,442
Cancer 6 | 2,499
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,955
oligodendroglioma 6 | 2,850
primitive neuroectodermal tumor 6 | 3,035
Cognitive delay 5 | 608
Emery-Dreifuss muscular dystrophy 5 | 23
Global developmental delay 5 | 608
Infertility 5 | 188
Mental and motor retardation 5 | 608
Orbital separation excessive 5 | 244
Pick disease 5 | 1,894
adrenocortical carcinoma 5 | 1,428
aldosterone-producing adenoma 5 | 665
dermatomyositis 5 | 966
diabetes mellitus 5 | 1,728
group 4 medulloblastoma 5 | 1,855
interstitial cystitis 5 | 2,312
invasive ductal carcinoma 5 | 2,951
lung adenocarcinoma 5 | 2,716
lung carcinoma 5 | 2,843
Amyotrophic lateral sclerosis 4 | 451
Bipolar Disorder 4 | 666
Kidney cancer 4 | 2,613
Lipodystrophy 4 | 40
Neurodegenerative disease 4 | 414
Progeria 4 | 25
Rheumatoid arthritis 4 | 1,191
Schizophrenia 4 | 1,160
Short stature 4 | 531
acute quadriplegic myopathy 4 | 1,158
astrocytic glioma 4 | 2,597
colon cancer 4 | 1,478
mucosa-associated lymphoid tissue lymphoma 4 | 484
pancreatic cancer 4 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
pituitary cancer 4 | 1,972
primary pancreatic ductal adenocarcinoma 4 | 1,109
subependymal giant cell astrocytoma 4 | 2,287
tuberculosis 4 | 2,010
ulcerative colitis 4 | 1,819
Acquired scoliosis 3 | 281
Atopic dermatitis 3 | 952
Cardiomyopathy 3 | 116
Cerebellar Ataxia 3 | 304
Curvature of spine 3 | 282
Delayed speech and language development 3 | 112
Duchenne muscular dystrophy 3 | 601
Epilepsy 3 | 792
Failure to gain weight 3 | 365
Frontotemporal dementia 3 | 51
HIV Infections 3 | 102
Hyperglycemia 3 | 137
Hyperreflexia 3 | 209
Language Delay 3 | 112
Male infertility 3 | 206
Multiple Sclerosis 3 | 540
Muscle Spasticity 3 | 195
Muscle hypotonia 3 | 571
Parkinson's disease 3 | 392
Pediatric failure to thrive 3 | 365
Progressive disorder 3 | 142
Speech Delay 3 | 112
Speech impairment 3 | 112
Tremor 3 | 113
active Crohn's disease 3 | 922
acute myeloid leukemia 3 | 783
juvenile dermatomyositis 3 | 1,187
nasopharyngeal carcinoma 3 | 1,058
posterior fossa group A ependymoma 3 | 468
primary Sjogren syndrome 3 | 735
spina bifida 3 | 1,074
Broad flat nasal bridge 2 | 236
Byzanthine arch palate 2 | 194
Cocaine-Related Disorders 2 | 92
Elevated creatine kinase 2 | 110
Kidney disease 2 | 430
Mood Disorders 2 | 184
Nasal bridge wide 2 | 236
active ulcerative colitis 2 | 764

Tissue

Endocrine System 42 | 18,159
Liver and Pancreas 41 | 16,750
Male tissues 40 | 17,142
Female tissues 39 | 17,400
Nervous System 39 | 16,725
Skin and soft tissues 39 | 17,230
Digestive Tract 38 | 17,369
Urinary Tract 38 | 16,678
Blood and immune system 37 | 16,909
Respiratory system 36 | 16,393
Cardiovascular System 35 | 15,192

Target Family

Non-IDG 25 | 12,091
Enzyme 9 | 4,145
Transcription Factor 3 | 1,400
Epigenetic 2 | 242
Ion Channel 2 | 344
Transporter 2 | 473
GPCR 1 | 408
Kinase 1 | 634

GO Component

nuclear inner membrane 45 | 45
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Chromobox protein homolog 3 CBX3 Tbio Epigenetic -2.00023 90.5 366
Lamina-associated polypeptide 2, isoforms beta/gamma TMPO Tbio Non-IDG -2.11834 246.0 283
Protein ATP1B4 ATP1B4 Tdark Transporter -0.67056 4.78 35
E3 ubiquitin-protein ligase RNF13 RNF13 Tbio Enzyme -0.84775 9.69 90
Probable C-mannosyltransferase DPY19L2 DPY19L2 Tbio Enzyme -1.83182 120.9 96
Nuclear envelope integral membrane protein 1 NEMP1 Tdark Non-IDG -0.09691 1.96 20
Mothers against decapentaplegic homolog 3 SMAD3 Tbio Transcription Factor -3.19667 1403.6 1526
Nurim NRM Tbio Non-IDG -1.42612 24.1 45
Serine/threonine-protein kinase/endoribonuclease IRE1 ERN1 Tchem Kinase -2.44644 224.3 489
NAD-dependent protein deacetylase sirtuin-1 SIRT1 Tchem Epigenetic -3.50639 3413.7 733