Development Level

Tbio 13 | 11,445

IMPC Phenotype

preweaning lethality, complete... 2 | 979
abnormal coat- hair morphology 1 | 19
abnormal hair texture 1 | 4
abnormal heart morphology 1 | 162
decreased body weight 1 | 161
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
hypoactivity 1 | 132
increased circulating aspartat... 1 | 15
increased hematocrit 1 | 46
increased mean corpuscular hem... 1 | 36
increased mean corpuscular vol... 1 | 92

Disease

Carcinoma 11 | 11,493
ovarian cancer 8 | 8,520
lung cancer 7 | 4,740
atypical teratoid / rhabdoid tumor 6 | 5,112
glioblastoma 6 | 5,792
osteosarcoma 6 | 7,950
Kidney cancer 5 | 2,613
Multiple myeloma 5 | 1,332
medulloblastoma, large-cell 5 | 6,241
psoriasis 5 | 6,694
astrocytic glioma 4 | 2,597
group 3 medulloblastoma 4 | 4,104
malignant mesothelioma 4 | 3,232
primitive neuroectodermal tumor 4 | 3,035
Ataxia, Appendicular 3 | 25
Ataxia, Truncal 3 | 21
Cancer 3 | 2,499
Deglutition Disorders 3 | 132
Dysarthria 3 | 192
Neurodegenerative disease 3 | 414
Progressive disorder 3 | 142
Waldenstrons macroglobulinemia 3 | 765
dermatomyositis 3 | 966
ependymoma 3 | 4,679
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
oligodendroglioma 3 | 2,850
tuberculosis 3 | 2,010
Adult onset 2 | 82
Amyotrophic lateral sclerosis 2 | 451
Aplastic Anemia 2 | 21
Atrophy of cerebellum 2 | 103
Attention deficit hyperactivity disorder 2 | 278
Autosomal dominant cerebellar ataxia 2 | 33
Autosomal recessive predisposition 2 | 1,442
Babinski Reflex 2 | 100
Blepharoptosis 2 | 231
Breast cancer 2 | 3,578
Cerebellar Ataxia 2 | 304
Cerebellar degeneration 2 | 103
Choreatic disease 2 | 52
Decreased vibratory sense 2 | 7
Dilated fourth ventricle 2 | 4
Distal amyotrophy 2 | 51
Dysmetric saccades 2 | 9
Impaired horizontal smooth pursuit 2 | 6
Infratentorial atrophy 2 | 103
Machado-Joseph disease 2 | 18
Nerve Degeneration 2 | 121
Nijmegen breakage syndrome 2 | 24
Pick disease 2 | 1,894
Progressive cerebellar ataxia 2 | 13
Sphincter disturbances 2 | 16
Spinocerebellar Ataxias 2 | 34
Spinocerebellar ataxia type 1 2 | 16
Spinocerebellar tract degeneration 2 | 4
Supranuclear ophthalmoplegia 2 | 4
acute myeloid leukemia 2 | 783
acute quadriplegic myopathy 2 | 1,158
adrenocortical carcinoma 2 | 1,428
adult high grade glioma 2 | 3,801
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
lung adenocarcinoma 2 | 2,716
pituitary cancer 2 | 1,972
subependymal giant cell astrocytoma 2 | 2,287
ulcerative colitis 2 | 1,819
Acute necrotizing encephalitis 1 | 2
Ataxia telangiectasia 1 | 34
Birthmark 1 | 35
Bronchiectasis 1 | 64
Cafe-au-Lait Spots 1 | 37
Cerebellar Dysmetria 1 | 56
Choanal Atresia 1 | 42
Chromosome Breakage 1 | 36
Diplopia 1 | 8
Dysdiadochokinesis 1 | 25
Gait, Unsteady 1 | 29
Hemophagocytic lymphohistiocytosis 1 | 30
Hereditary Breast and Ovarian Cancer Syndrome 1 | 14
Increased chromosomal breakage 1 | 27
Inflammatory myofibroblastic tumor 1 | 8
Lichen planus 1 | 16
Mastoiditis 1 | 8
Muscle Cramp 1 | 55
Nystagmus, End-Position 1 | 12
Olivopontocerebellar atrophy 1 | 9
Ovarian Failure, Premature 1 | 9
PARKINSON DISEASE, LATE-ONSET 1 | 20
Papillary thyroid carcinoma 1 | 43
Postural instability 1 | 19
Recurrent bronchitis 1 | 23
Restless legs syndrome 1 | 27
Sinusitis 1 | 65
Slowed saccades 1 | 12
Spinocerebellar ataxia type 2 1 | 23
Stomatitis 1 | 21
Syphilis 1 | 17
Thyroid Neoplasm 1 | 37
Thyroid Neoplasms 1 | 34
Werner syndrome 1 | 29
clinical depression 1 | 6

Tissue

Endocrine System 13 | 18,159
Female tissues 13 | 17,400
Blood and immune system 12 | 16,909
Cardiovascular System 12 | 15,192
Digestive Tract 12 | 17,369
Liver and Pancreas 12 | 16,750
Male tissues 12 | 17,142
Nervous System 12 | 16,725
Respiratory system 12 | 16,393
Skin and soft tissues 12 | 17,230
Urinary Tract 12 | 16,678

Target Family

Non-IDG 9 | 12,091
Enzyme 4 | 4,145

GO Component

nuclear inclusion body 13 | 13
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Polyadenylate-binding protein 2 PABPN1 Tbio Non-IDG -2.48757 316.4 120
Nucleoprotein TPR TPR Tbio Non-IDG -2.11491 135.6 161
Nuclear pore complex protein Nup98-Nup96 NUP98 Tbio Enzyme -2.26305 200.9 189
Nuclear pore complex protein Nup153 NUP153 Tbio Non-IDG -2.14396 129.9 100
Ataxin-3-like protein ATXN3L Tbio Non-IDG -0.28506 1.65 37
SMC5-SMC6 complex localization factor protein 1 SLF1 Tbio Non-IDG -0.93112 9.24 119
E3 ubiquitin-protein ligase RAD18 RAD18 Tbio Enzyme -2.22905 169.1 271
E3 ubiquitin-protein ligase CHIP STUB1 Tbio Enzyme -2.96877 926.8 351
E3 SUMO-protein ligase RanBP2 RANBP2 Tbio Enzyme -2.24609 178.6 172
Nibrin NBN Tbio Non-IDG -1.95649 97.2 1094