Development Level

Tbio 19 | 11,651
Tchem 2 | 1,388
Tclin 1 | 612
Tdark 1 | 6,593

IMPC Phenotype

preweaning lethality, incomple... 5 | 499
preweaning lethality, complete... 3 | 979
decreased bone mineral density 2 | 126
increased bone mineral content 2 | 108
increased bone mineral density 2 | 72
abnormal bone structure 1 | 187
abnormal coat-hair pigmentatio... 1 | 64
abnormal embryo size 1 | 220
abnormal heart left ventricle ... 1 | 16
abnormal spleen morphology 1 | 55
abnormal vitreous body morphol... 1 | 10
decreased basophil cell number 1 | 16
decreased body length 1 | 101
decreased bone mineral content 1 | 151
decreased circulating HDL chol... 1 | 68
decreased heart rate 1 | 18
decreased lean body mass 1 | 135
decreased prepulse inhibition 1 | 82
decreased threshold for audito... 1 | 26
decreased total body fat amoun... 1 | 207
edema 1 | 59
female infertility 1 | 60
fusion of vertebral arches 1 | 7
hyperactivity 1 | 148
increased body length 1 | 32
increased circulating HDL chol... 1 | 80
increased grip strength 1 | 41
increased hemoglobin content 1 | 45
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
prolonged RR interval 1 | 8
vertebral fusion 1 | 23
vertebral transformation 1 | 12

Disease

Carcinoma 15 | 11,493
ovarian cancer 13 | 8,520
medulloblastoma, large-cell 12 | 6,241
Cancer 11 | 2,499
glioblastoma 11 | 5,792
osteosarcoma 11 | 7,950
atypical teratoid / rhabdoid tumor 10 | 5,112
Breast cancer 9 | 3,578
group 3 medulloblastoma 9 | 4,104
lung adenocarcinoma 9 | 2,716
lung cancer 9 | 4,740
astrocytic glioma 8 | 2,597
diabetes mellitus 8 | 1,728
ependymoma 8 | 4,679
psoriasis 7 | 6,694
Waldenstrons macroglobulinemia 6 | 765
adult high grade glioma 6 | 3,801
invasive ductal carcinoma 6 | 2,951
primitive neuroectodermal tumor 6 | 3,035
adrenocortical carcinoma 5 | 1,428
malignant mesothelioma 5 | 3,232
pancreatic cancer 5 | 2,398
Astrocytoma, Pilocytic 4 | 3,081
Prostatic Neoplasms 4 | 495
Rheumatoid arthritis 4 | 1,191
Schizophrenia 4 | 1,160
dermatomyositis 4 | 966
ductal carcinoma in situ 4 | 1,745
interstitial cystitis 4 | 2,312
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
oligodendroglioma 4 | 2,850
Adenoid Cystic Carcinoma 3 | 99
Alzheimer's disease 3 | 658
Carcinoma, Adenoid Cystic 3 | 99
Huntington's disease 3 | 76
Immune system cancer 3 | 140
Intellectual disability 3 | 1,016
Kidney cancer 3 | 2,613
Pick disease 3 | 1,894
acute myeloid leukemia 3 | 783
breast carcinoma 3 | 1,638
cystic fibrosis 3 | 1,696
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
non-small cell lung cancer 3 | 2,890
primary pancreatic ductal adenocarcinoma 3 | 1,109
Bloom syndrome 2 | 29
Breast Neoplasms 2 | 445
Craniofacial Abnormalities 2 | 151
Decreased projection of midface 2 | 105
Endometriosis 2 | 540
Everted lower lip vermilion 2 | 54
Growth Disorders 2 | 35
Hypotrophic malar bone 2 | 129
Hypotrophic midface 2 | 105
Liver cancer 2 | 604
Lymphoid leukemia 2 | 160
MYELODYSPLASTIC SYNDROME 2 | 53
Malar flattening 2 | 129
Mammary Neoplasms 2 | 425
Midface retrusion 2 | 105
Mood Disorders 2 | 184
Multiple myeloma 2 | 1,332
Orbital separation excessive 2 | 244
Parkinson's disease 2 | 392
Protruding lower lip 2 | 54
Sensorineural Hearing Loss (disorder) 2 | 284
Small midface 2 | 105
active Crohn's disease 2 | 922
aldosterone-producing adenoma 2 | 665
gastric carcinoma 2 | 807
hepatocellular carcinoma 2 | 547
medulloblastoma 2 | 720
nasopharyngeal carcinoma 2 | 1,058
pediatric high grade glioma 2 | 1,064
pituitary cancer 2 | 1,972
primary Sjogren syndrome 2 | 735
tuberculosis and treatment for 6 months 2 | 409
Acquired flat foot 1 | 72
Ambiguous Genitalia 1 | 24
Decreased size of teeth 1 | 62
Decreased width of tooth 1 | 59
Demyelinating Diseases 1 | 7
Diabetic retinopathy 1 | 56
Flatfoot 1 | 73
Full lower lip 1 | 64
Heart Diseases 1 | 43
Hypoplasia of scrotum 1 | 24
Infantile muscular hypotonia 1 | 12
Lung Injury 1 | 20
Measles 1 | 22
Microcytic hypochromic anemia (disorder) 1 | 10
Microdontia (disorder) 1 | 59
Myocardial Reperfusion Injury 1 | 37
Pneumonia, Pneumococcal 1 | 6
Prominent lower lip 1 | 64
Shared Paranoid Disorder 1 | 5
Streptococcal pneumonia 1 | 6
Xeroderma pigmentosum 1 | 43
Xeroderma pigmentosum group F 1 | 22

Tissue

Blood and immune system 23 | 16,909
Endocrine System 23 | 18,159
Female tissues 23 | 17,400
Male tissues 23 | 17,142
Nervous System 23 | 16,725
Respiratory system 23 | 16,393
Cardiovascular System 22 | 15,192
Digestive Tract 22 | 17,369
Liver and Pancreas 22 | 16,750
Skin and soft tissues 22 | 17,230
Urinary Tract 22 | 16,678

Target Family

Epigenetic 12 | 242
Non-IDG 6 | 12,091
Transcription Factor 3 | 1,400
Enzyme 2 | 4,145

GO Component

nuclear heterochromatin 23 | 23
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Chromobox protein homolog 3 CBX3 Tbio Epigenetic -2.00023 90.5 366
DNA (cytosine-5)-methyltransferase 3A DNMT3A Tclin Epigenetic -2.91291 722.8 693
E3 ubiquitin-protein ligase UHRF1 UHRF1 Tbio Epigenetic 0.00000 279
DNA-binding protein SATB1 SATB1 Tbio Transcription Factor -2.28849 219.7 322
Histone H2A.Z H2AFZ Tbio Non-IDG -2.53312 344.8 285
NAD-dependent protein deacetylase sirtuin-2 SIRT2 Tchem Epigenetic -2.83863 706.1 386
Histone H1.4 HIST1H1E Tbio Non-IDG -1.66217 42.7 170
NAD-dependent protein deacetylase sirtuin-1 SIRT1 Tchem Epigenetic -3.50639 3413.7 733
Crossover junction endonuclease EME1 EME1 Tbio Enzyme -1.69458 48.2 143
PC4 and SFRS1-interacting protein PSIP1 Tbio Epigenetic -2.56190 391.2 150