Development Level

Tbio 112 | 10,625
Tchem 19 | 1,890
Tdark 17 | 7,003
Tclin 8 | 602

Collection

Eligible Ion Channel Proteins 1 | 117

IMPC Term

preweaning lethality, complete... 8 | 633
preweaning lethality, incomple... 5 | 260
decreased rib number 4 | 59
decreased lumbar vertebrae num... 3 | 62
increased sacral vertebrae num... 3 | 62
abnormal behavior 2 | 226
decreased body weight 2 | 174
decreased bone mineral content 2 | 157
increased mean corpuscular hem... 2 | 93
increased mean corpuscular vol... 2 | 91
narrow eye opening 2 | 15
abnormal bone mineralization 1 | 55
abnormal coat/hair pigmentatio... 1 | 54
abnormal femur morphology 1 | 14
abnormal iris morphology 1 | 12
abnormal maxilla morphology 1 | 16
abnormal placement of pupils 1 | 4
abnormal retinal inner nuclear... 1 | 5
abnormal rib morphology 1 | 28
abnormal snout morphology 1 | 18
abnormal thoracic vertebrae mo... 1 | 16
abnormal tibia morphology 1 | 14
abnormal tooth morphology 1 | 24
decreased CD8-positive, alpha-... 1 | 26
decreased KLRG1+ CD8 alpha bet... 1 | 8
decreased KLRG1-positive NK ce... 1 | 9
decreased T cell number 1 | 31
decreased body length 1 | 108
decreased caudal vertebrae num... 1 | 49
decreased circulating LDL chol... 1 | 37
decreased circulating alanine ... 1 | 53
decreased circulating alkaline... 1 | 41
decreased circulating aspartat... 1 | 27
decreased circulating calcium ... 1 | 33
decreased circulating choleste... 1 | 85
decreased circulating glucose ... 1 | 121
decreased circulating iron lev... 1 | 25
decreased fasted circulating g... 1 | 49
decreased grip strength 1 | 123
decreased lactate dehydrogenas... 1 | 14
decreased mean corpuscular vol... 1 | 50
decreased total retina thickne... 1 | 20
embryonic lethality prior to t... 1 | 187
enlarged seminal vesicle 1 | 1
fusion of vertebral arches 1 | 7
hyperactivity 1 | 108
hypoactivity 1 | 89
impaired glucose tolerance 1 | 52
increased CD4-positive, CD25-p... 1 | 18
increased Ly6C low monocyte nu... 1 | 8
increased circulating alanine ... 1 | 11
increased circulating alkaline... 1 | 119
increased circulating aspartat... 1 | 17
increased circulating iron lev... 1 | 25
increased circulating triglyce... 1 | 24
increased exploration in new e... 1 | 56
increased fasted circulating g... 1 | 68
increased grip strength 1 | 83
increased heart weight 1 | 37
increased or absent threshold ... 1 | 128
increased respiratory quotient 1 | 12
increased spleen weight 1 | 3
irregularly shaped pupil 1 | 7
thrombocytopenia 1 | 46
vertebral fusion 1 | 23
vertebral transformation 1 | 12

Disease

ovarian cancer 91 | 8,484
osteosarcoma 83 | 7,933
medulloblastoma, large-cell 78 | 6,234
glioblastoma 71 | 5,572
lung cancer 71 | 4,466
psoriasis 60 | 6,685
atypical teratoid / rhabdoid tumor 52 | 4,369
primitive neuroectodermal tumor 45 | 3,031
pediatric high grade glioma 42 | 2,712
intraductal papillary-mucinous neoplasm (IPMN) 40 | 3,289
Breast cancer 38 | 3,094
invasive ductal carcinoma 37 | 2,950
group 3 medulloblastoma 36 | 2,254
malignant mesothelioma 36 | 3,162
intraductal papillary-mucinous carcinoma (IPMC) 35 | 2,988
non-small cell lung cancer 35 | 2,798
oligodendroglioma 34 | 2,849
pilocytic astrocytoma 33 | 3,086
Cancer 28 | 2,346
lung adenocarcinoma 28 | 2,713
intraductal papillary-mucinous adenoma (IPMA) 27 | 2,956
Pick disease 26 | 1,893
subependymal giant cell astrocytoma 26 | 2,287
dermatomyositis 25 | 933
adrenocortical carcinoma 24 | 1,427
Carcinoma 23 | 2,147
astrocytic glioma 23 | 2,241
pancreatic cancer 23 | 2,300
ependymoma 22 | 2,514
lung carcinoma 22 | 2,844
Multiple myeloma 21 | 1,327
acute quadriplegic myopathy 21 | 1,157
astrocytoma 21 | 1,493
diabetes mellitus 21 | 1,663
ductal carcinoma in situ 21 | 1,745
pancreatic ductal adenocarcinoma liver metastasis 21 | 1,795
adult high grade glioma 20 | 2,148
colon cancer 20 | 1,475
posterior fossa group A ependymoma 20 | 1,511
breast carcinoma 18 | 1,614
group 4 medulloblastoma 18 | 1,875
medulloblastoma 18 | 1,524
Waldenstrons macroglobulinemia 17 | 765
pituitary cancer 17 | 1,972
Rheumatoid Arthritis 16 | 1,160
atypical teratoid/rhabdoid tumor 16 | 1,095
posterior fossa group B ependymoma 16 | 1,530
tuberculosis 16 | 1,557
nasopharyngeal carcinoma 15 | 1,056
primary pancreatic ductal adenocarcinoma 15 | 1,271
interstitial cystitis 14 | 2,299
ulcerative colitis 14 | 2,087
acute myeloid leukemia 13 | 780
gastric carcinoma 13 | 832
sonic hedgehog group medulloblastoma 13 | 1,482
juvenile dermatomyositis 12 | 1,189
primary Sjogren syndrome 12 | 789
aldosterone-producing adenoma 11 | 664
cutaneous lupus erythematosus 10 | 1,056
Amyotrophic Lateral Sclerosis 9 | 431
Atopic dermatitis 9 | 944
Neurodegenerative disease 9 | 383
cystic fibrosis 9 | 1,665
non primary Sjogren syndrome sicca 9 | 840
progressive supranuclear palsy 9 | 674
spina bifida 9 | 1,064
Alzheimer's disease 8 | 644
Atherosclerosis 8 | 275
Emery-Dreifuss muscular dystrophy 8 | 24
IGA Glomerulonephritis 8 | 454
Mammary Neoplasms 8 | 410
Obesity 8 | 616
Prostatic Neoplasms 8 | 471
active Crohn's disease 8 | 918
autosomal dominant Emery-Dreifuss muscular dystrophy 8 | 499
mucosa-associated lymphoid tissue lymphoma 8 | 480
Asthma 7 | 349
Chronic Lymphocytic Leukemia 7 | 242
Duchenne muscular dystrophy 7 | 602
Endometriosis 7 | 535
Gaucher disease type 1 7 | 171
Schizophrenia 7 | 501
Vascular disease 7 | 281
esophageal adenocarcinoma 7 | 737
sarcoidosis 7 | 358
tuberculosis and treatment for 6 months 7 | 686
Diabetes Mellitus, Experimental 6 | 106
HIV Infections 6 | 100
hereditary spastic paraplegia 6 | 313
periodontitis 6 | 269
tuberculosis and treatment for 3 months 6 | 327
Cerebrovascular disease 5 | 231
Down syndrome 5 | 548
Lipodystrophy 5 | 32
Progeria 5 | 22
fibroadenoma 5 | 557
Becker muscular dystrophy 4 | 187
Diabetes Mellitus, Non-Insulin-Dependent 4 | 157
chronic rhinosinusitis 4 | 512
limb girdle muscular dystrophy 2A 4 | 156

Tissue

Female tissues 156 | 18,647
Liver and Pancreas 156 | 18,136
Nervous System 156 | 18,561
Blood and immune system 155 | 17,995
Cardiovascular System 155 | 17,958
Endocrine System 155 | 18,512
Male tissues 155 | 17,969
Urinary Tract 155 | 18,444
Digestive Tract 154 | 18,473
Skin and soft tissues 152 | 18,115
Respiratory system 150 | 17,484

Target Family

Non-IDG 95 | 11,971
Enzyme 40 | 4,146
Ion Channel 5 | 341
Epigenetic 4 | 242
Kinase 3 | 634
Transcription Factor 3 | 1,400
Transporter 3 | 473
GPCR 2 | 406
TF/Epigenetic 1 | 38

GO Component

nuclear envelope 156 | 156
nucleus 5,107 | 5,107
cytoplasm 4,985 | 4,985
plasma membrane 4,118 | 4,118
integral component of membrane 3,679 | 3,679
cytosol 3,265 | 3,265
extracellular exosome 2,758 | 2,758
nucleoplasm 2,717 | 2,717
membrane 1,906 | 1,906
extracellular region 1,493 | 1,493
integral component of plasma m... 1,406 | 1,406
extracellular space 1,304 | 1,304
mitochondrion 1,231 | 1,231
Golgi apparatus 864 | 864
endoplasmic reticulum 859 | 859
endoplasmic reticulum membrane 848 | 848
nucleolus 815 | 815
Golgi membrane 659 | 659
perinuclear region of cytoplas... 611 | 611
cell surface 594 | 594
intracellular 548 | 548
intracellular membrane-bounded... 537 | 537
cell junction 451 | 451
mitochondrial inner membrane 425 | 425
centrosome 409 | 409
focal adhesion 383 | 383
protein complex 355 | 355
cytoskeleton 343 | 343
dendrite 329 | 329
mitochondrial matrix 322 | 322
cell-cell adherens junction 307 | 307
neuronal cell body 303 | 303
microtubule 294 | 294
lysosomal membrane 278 | 278
apical plasma membrane 277 | 277
proteinaceous extracellular ma... 244 | 244
neuron projection 229 | 229
nuclear membrane 218 | 218
early endosome 217 | 217
axon 214 | 214
lysosome 210 | 210
endosome 208 | 208
actin cytoskeleton 205 | 205
external side of plasma membra... 205 | 205
postsynaptic membrane 204 | 204
extracellular matrix 198 | 198
nuclear speck 197 | 197
membrane raft 196 | 196
endoplasmic reticulum lumen 192 | 192
transcription factor complex 184 | 184
endosome membrane 182 | 182
early endosome membrane 180 | 180
basolateral plasma membrane 174 | 174
nuclear chromatin 169 | 169
synapse 166 | 166
cell-cell junction 161 | 161
lamellipodium 153 | 153
mitochondrial outer membrane 148 | 148
blood microparticle 147 | 147
myelin sheath 144 | 144
postsynaptic density 144 | 144
cytoplasmic vesicle 143 | 143
microtubule organizing center 137 | 137
cytoplasmic, membrane-bounded ... 132 | 132
ER to Golgi transport vesicle ... 131 | 131
microtubule cytoskeleton 127 | 127
receptor complex 127 | 127
phagocytic vesicle membrane 126 | 126
cytoplasmic vesicle membrane 125 | 125
midbody 125 | 125
trans-Golgi network 124 | 124
cell cortex 119 | 119
cilium 118 | 118
late endosome 116 | 116
spindle 116 | 116
intracellular ribonucleoprotei... 114 | 114
vesicle 112 | 112
Z disc 110 | 110
bicellular tight junction 110 | 110
anchored component of membrane 109 | 109
growth cone 109 | 109
integral component of lumenal ... 108 | 108
late endosome membrane 107 | 107
endomembrane system 106 | 106
centriole 105 | 105
recycling endosome 104 | 104
spindle pole 104 | 104
perikaryon 103 | 103
integral component of endoplas... 101 | 101
intermediate filament 101 | 101
melanosome 101 | 101
chromosome 100 | 100
dendritic spine 99 | 99
ubiquitin ligase complex 99 | 99
peroxisome 98 | 98
nuclear matrix 97 | 97
PML body 94 | 94
Golgi lumen 93 | 93
keratin filament 93 | 93
trans-Golgi network membrane 92 | 92

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Nucleoprotein TPR TPR Tbio Non-IDG -2.07876 130.9 158
Lymphoid-restricted membrane protein LRMP Tbio Non-IDG -1.17754 15.9 54
Nuclear pore complex protein Nup98-Nup96 NUP98 Tbio Enzyme -2.21148 186.3 172
Emerin EMD Tbio Non-IDG -2.77469 617.6 238
Meiosis-specific nuclear structural protein 1 MNS1 Tbio Non-IDG -1.16311 14.2 55
Centromere protein F CENPF Tbio Non-IDG -1.98596 103.0 180
Nucleoporin p58/p45 NUP58 Tdark Non-IDG -0.70757 5.23 31
ATP-binding cassette sub-family F member 1 ABCF1 Tbio Transporter -1.10503 13.7 196
Annexin A11 ANXA11 Tbio Non-IDG -1.63325 49.7 192
Ran GTPase-activating protein 1 RANGAP1 Tbio Enzyme -1.81728 64.0 214