Development Level

Tbio 124 | 11,651
Tdark 17 | 6,593
Tchem 12 | 1,388
Tclin 7 | 612

IMPC Phenotype

preweaning lethality, complete... 14 | 979
preweaning lethality, incomple... 8 | 499
abnormal embryo size 3 | 220
increased mean corpuscular hem... 3 | 96
abnormal behavior 2 | 298
decreased body weight 2 | 161
decreased bone mineral content 2 | 151
decreased bone mineral density 2 | 126
decreased caudal vertebrae num... 2 | 53
decreased circulating alkaline... 2 | 46
decreased circulating calcium ... 2 | 36
decreased vertical activity 2 | 208
embryonic lethality prior to t... 2 | 278
hypoactivity 2 | 132
improved glucose tolerance 2 | 79
increased circulating alkaline... 2 | 122
increased mean corpuscular vol... 2 | 92
increased startle reflex 2 | 112
small testis 2 | 58
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal coat-hair pigmentatio... 1 | 64
abnormal craniofacial morpholo... 1 | 33
abnormal femur morphology 1 | 14
abnormal forebrain morphology 1 | 10
abnormal heart left ventricle ... 1 | 16
abnormal heart morphology 1 | 162
abnormal hindbrain morphology 1 | 10
abnormal incisor color 1 | 3
abnormal iris transilluminatio... 1 | 2
abnormal lens morphology 1 | 81
abnormal midbrain morphology 1 | 10
abnormal neural tube closure 1 | 46
abnormal placenta size 1 | 20
abnormal retina morphology 1 | 71
abnormal retinal inner nuclear... 1 | 8
abnormal tail morphology 1 | 25
abnormal testis morphology 1 | 43
abnormal tibia morphology 1 | 14
abnormal vitreous body morphol... 1 | 10
anophthalmia 1 | 33
cataract 1 | 92
cornea ulcer 1 | 1
corneal opacity 1 | 32
decreased CD4-positive, alpha ... 1 | 7
decreased CD8-positive, alpha-... 1 | 8
decreased T cell number 1 | 15
decreased circulating LDL chol... 1 | 38
decreased circulating alanine ... 1 | 47
decreased circulating aspartat... 1 | 34
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased circulating iron lev... 1 | 32
decreased circulating sodium l... 1 | 22
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased fasted circulating g... 1 | 65
decreased lactate dehydrogenas... 1 | 16
decreased lean body mass 1 | 135
decreased lumbar vertebrae num... 1 | 2
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular vol... 1 | 79
decreased sacral vertebrae num... 1 | 1
decreased total body fat amoun... 1 | 207
decreased total retina thickne... 1 | 17
edema 1 | 59
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
enlarged heart 1 | 210
enlarged seminal vesicle 1 | 10
female infertility 1 | 60
fused cornea and lens 1 | 5
fusion of vertebral arches 1 | 7
hemorrhage 1 | 23
hyperactivity 1 | 148
impaired glucose tolerance 1 | 75
increased IgG2b level 1 | 1
increased anti-nuclear antigen... 1 | 19
increased circulating alanine ... 1 | 13
increased circulating aspartat... 1 | 15
increased circulating calcium ... 1 | 34
increased circulating creatini... 1 | 38
increased circulating iron lev... 1 | 30
increased circulating triglyce... 1 | 42
increased fasted circulating g... 1 | 76
increased lean body mass 1 | 172
increased monocyte cell number 1 | 63
increased or absent threshold ... 1 | 101
increased sacral vertebrae num... 1 | 1
increased spleen weight 1 | 10
increased total body fat amoun... 1 | 134
iris synechia 1 | 3
long tibia 1 | 25
male infertility 1 | 123
narrow eye opening 1 | 12
prolonged ST segment 1 | 36
small superior vagus ganglion 1 | 74
thrombocytopenia 1 | 56
vertebral fusion 1 | 23
vertebral transformation 1 | 12

Disease

Carcinoma 109 | 11,493
ovarian cancer 91 | 8,520
osteosarcoma 83 | 7,950
medulloblastoma, large-cell 78 | 6,241
lung cancer 73 | 4,740
glioblastoma 71 | 5,792
atypical teratoid / rhabdoid tumor 63 | 5,112
group 3 medulloblastoma 59 | 4,104
psoriasis 59 | 6,694
ependymoma 48 | 4,679
adult high grade glioma 46 | 3,801
primitive neuroectodermal tumor 43 | 3,035
Breast cancer 41 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 40 | 3,291
invasive ductal carcinoma 39 | 2,951
malignant mesothelioma 37 | 3,232
intraductal papillary-mucinous carcinoma (IPMC) 35 | 2,989
Astrocytoma, Pilocytic 34 | 3,081
non-small cell lung cancer 33 | 2,890
oligodendroglioma 33 | 2,850
Cancer 29 | 2,499
astrocytic glioma 27 | 2,597
intraductal papillary-mucinous adenoma (IPMA) 27 | 2,955
Kidney cancer 26 | 2,613
lung adenocarcinoma 26 | 2,716
pancreatic cancer 26 | 2,398
Pick disease 25 | 1,894
dermatomyositis 25 | 966
subependymal giant cell astrocytoma 25 | 2,287
adrenocortical carcinoma 23 | 1,428
Multiple myeloma 22 | 1,332
acute quadriplegic myopathy 22 | 1,158
lung carcinoma 22 | 2,843
pancreatic ductal adenocarcinoma liver metastasis 22 | 1,962
tuberculosis 22 | 2,010
Autosomal recessive predisposition 21 | 1,442
ductal carcinoma in situ 21 | 1,745
diabetes mellitus 20 | 1,728
breast carcinoma 19 | 1,638
colon cancer 19 | 1,478
group 4 medulloblastoma 19 | 1,855
Waldenstrons macroglobulinemia 17 | 765
astrocytoma 17 | 1,146
Rheumatoid arthritis 16 | 1,191
nasopharyngeal carcinoma 16 | 1,058
pituitary cancer 16 | 1,972
pediatric high grade glioma 15 | 1,064
Schizophrenia 14 | 1,160
interstitial cystitis 14 | 2,312
primary pancreatic ductal adenocarcinoma 14 | 1,109
acute myeloid leukemia 13 | 783
gastric carcinoma 13 | 807
Neurodegenerative disease 12 | 414
juvenile dermatomyositis 12 | 1,187
ulcerative colitis 12 | 1,819
Alzheimer's disease 11 | 658
Cognitive delay 11 | 608
Global developmental delay 11 | 608
Liver Cirrhosis, Experimental 11 | 769
Mental and motor retardation 11 | 608
aldosterone-producing adenoma 11 | 665
primary Sjogren syndrome 11 | 735
Amyotrophic lateral sclerosis 10 | 451
Atherosclerosis 10 | 291
Intellectual disability 10 | 1,016
cutaneous lupus erythematosus 10 | 1,057
non primary Sjogren syndrome sicca 10 | 891
progressive supranuclear palsy 10 | 676
spina bifida 10 | 1,074
Atopic dermatitis 9 | 952
Emery-Dreifuss muscular dystrophy 9 | 23
Mammary Neoplasms 9 | 425
Obesity 9 | 678
Prostatic Neoplasms 9 | 495
cystic fibrosis 9 | 1,696
Breast Neoplasms 8 | 445
Chronic Lymphocytic Leukemia 8 | 262
Dull intelligence 8 | 645
Dysarthria 8 | 192
Epilepsy 8 | 792
Low intelligence 8 | 645
Mental Retardation 8 | 645
Mental deficiency 8 | 645
Poor school performance 8 | 645
active Crohn's disease 8 | 922
autosomal dominant Emery-Dreifuss muscular dystrophy 8 | 510
esophageal adenocarcinoma 8 | 737
mucosa-associated lymphoid tissue lymphoma 8 | 484
Asthma 7 | 385
Bipolar Disorder 7 | 666
Duchenne muscular dystrophy 7 | 601
HIV Infections 7 | 102
Muscle Spasticity 7 | 195
Progeria 7 | 25
Seizures 7 | 596
Vascular disease 7 | 319
hereditary spastic paraplegia 7 | 318
sarcoidosis 7 | 370
Depressive disorder 6 | 409
periodontitis 6 | 293

Tissue

Endocrine System 156 | 18,159
Digestive Tract 155 | 17,369
Liver and Pancreas 155 | 16,750
Skin and soft tissues 154 | 17,230
Urinary Tract 154 | 16,678
Blood and immune system 153 | 16,909
Female tissues 153 | 17,400
Male tissues 153 | 17,142
Nervous System 153 | 16,725
Respiratory system 152 | 16,393
Cardiovascular System 150 | 15,192

Target Family

Non-IDG 100 | 12,091
Enzyme 39 | 4,145
Ion Channel 5 | 344
Epigenetic 4 | 242
Kinase 3 | 634
Transcription Factor 3 | 1,400
Transporter 3 | 473
GPCR 2 | 408
TF/Epigenetic 1 | 38

GO Component

nuclear envelope 160 | 160
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Lamina-associated polypeptide 2, isoform alpha TMPO Tbio Non-IDG -2.11834 246.0 283
Chromobox protein homolog 3 CBX3 Tbio Epigenetic -2.00023 90.5 366
Ran-specific GTPase-activating protein RANBP1 Tbio Enzyme -1.80548 64.8 193
Lamina-associated polypeptide 2, isoforms beta/gamma TMPO Tbio Non-IDG -2.11834 246.0 283
Oxidoreductase HTATIP2 HTATIP2 Tbio Enzyme -1.67998 59.4 218
Importin subunit beta-1 KPNB1 Tbio Non-IDG -1.63038 38.8 174
Microsomal glutathione S-transferase 2 MGST2 Tbio Enzyme -1.15686 13.6 120
Protein ATP1B4 ATP1B4 Tdark Transporter -0.67056 4.78 35
ATP-dependent RNA helicase DDX19B DDX19B Tbio Enzyme -1.25103 10.1 252
Charged multivesicular body protein 2a CHMP2A Tbio Non-IDG -2.45155 278.6 88