Development Level

Tbio 16 | 11,445
Tchem 6 | 1,598
Tclin 1 | 613

IMPC Phenotype

decreased bone mineral content 2 | 151
decreased bone mineral density 2 | 126
male infertility 2 | 123
preweaning lethality, complete... 2 | 979
abnormal gait 1 | 69
abnormal kidney morphology 1 | 65
abnormal spleen morphology 1 | 55
decreased body length 1 | 101
decreased grip strength 1 | 116
decreased lean body mass 1 | 135
decreased lymphocyte cell numb... 1 | 83
decreased vertical activity 1 | 208
embryonic lethality prior to o... 1 | 239
female infertility 1 | 60
increased body temperature 1 | 9
increased mean platelet volume 1 | 45
increased neutrophil cell numb... 1 | 46
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
polycystic kidney 1 | 15
prenatal lethality prior to he... 1 | 87
small testis 1 | 58

Disease

osteosarcoma 18 | 7,950
ovarian cancer 18 | 8,520
glioblastoma 14 | 5,792
psoriasis 14 | 6,694
Carcinoma 13 | 11,493
lung cancer 13 | 4,740
medulloblastoma, large-cell 12 | 6,241
atypical teratoid / rhabdoid tumor 11 | 5,112
group 3 medulloblastoma 11 | 4,104
Breast cancer 9 | 3,578
Cancer 9 | 2,499
intraductal papillary-mucinous carcinoma (IPMC) 9 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,291
malignant mesothelioma 9 | 3,232
non-small cell lung cancer 9 | 2,890
invasive ductal carcinoma 8 | 2,951
breast carcinoma 7 | 1,638
colon cancer 7 | 1,478
lung adenocarcinoma 7 | 2,716
pituitary cancer 7 | 1,972
adrenocortical carcinoma 6 | 1,428
adult high grade glioma 6 | 3,801
ductal carcinoma in situ 6 | 1,745
hepatocellular carcinoma 6 | 547
pancreatic cancer 6 | 2,398
primitive neuroectodermal tumor 6 | 3,035
Intellectual disability 5 | 1,016
Pick disease 5 | 1,894
Short stature 5 | 531
cystic fibrosis 5 | 1,696
Cognitive delay 4 | 608
Global developmental delay 4 | 608
Mental and motor retardation 4 | 608
Multiple myeloma 4 | 1,332
Rheumatoid arthritis 4 | 1,191
Small head 4 | 374
Waldenstrons macroglobulinemia 4 | 765
astrocytic glioma 4 | 2,597
astrocytoma 4 | 1,146
cutaneous lupus erythematosus 4 | 1,057
ependymoma 4 | 4,679
gastric cancer 4 | 459
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
lung carcinoma 4 | 2,843
nasopharyngeal carcinoma 4 | 1,058
pancreatic carcinoma 4 | 562
tuberculosis 4 | 2,010
Astrocytoma, Pilocytic 3 | 3,081
Bloom syndrome 3 | 29
Breast Neoplasms 3 | 445
Dull intelligence 3 | 645
Epilepsy 3 | 792
Fetal Growth Retardation 3 | 189
Infant, Small for Gestational Age 3 | 176
Intrauterine retardation 3 | 176
Kidney cancer 3 | 2,613
Low intelligence 3 | 645
Lung Neoplasms 3 | 232
Mammary Neoplasms 3 | 425
Mental Retardation 3 | 645
Mental deficiency 3 | 645
Poor school performance 3 | 645
acute myeloid leukemia 3 | 783
acute quadriplegic myopathy 3 | 1,158
aldosterone-producing adenoma 3 | 665
dermatomyositis 3 | 966
group 4 medulloblastoma 3 | 1,855
non-small cell lung carcinoma 3 | 317
subependymal giant cell astrocytoma 3 | 2,287
Acquired scoliosis 2 | 281
Alzheimer's disease 2 | 658
Amyotrophic lateral sclerosis 2 | 451
Atopic dermatitis 2 | 952
Autosomal recessive predisposition 2 | 1,442
Carcinoma, Hepatocellular 2 | 228
Colonic Neoplasms 2 | 142
Concave bridge of nose 2 | 195
Curvature of spine 2 | 282
Depressed nasal bridge 2 | 195
Depressed nasal root/bridge 2 | 195
Endometriosis 2 | 540
Fanconi anemia 2 | 56
Highly variable severity 2 | 157
Liver carcinoma 2 | 240
Microcephaly 2 | 166
Muscle hypotonia 2 | 571
Recurrent respiratory infections 2 | 141
Schizophrenia 2 | 1,160
Seizures 2 | 596
Specific learning disability 2 | 47
Squamous cell carcinoma 2 | 129
Stomach Neoplasms 2 | 300
Variable expressivity 2 | 157
diabetes mellitus 2 | 1,728
inflammatory breast cancer 2 | 286
interstitial cystitis 2 | 2,312
pediatric high grade glioma 2 | 1,064
spina bifida 2 | 1,074
tuberculosis and treatment for 6 months 2 | 409
ulcerative colitis 2 | 1,819

Tissue

Endocrine System 23 | 18,159
Blood and immune system 22 | 16,909
Cardiovascular System 22 | 15,192
Digestive Tract 22 | 17,369
Female tissues 22 | 17,400
Liver and Pancreas 22 | 16,750
Male tissues 22 | 17,142
Nervous System 22 | 16,725
Respiratory system 22 | 16,393
Skin and soft tissues 22 | 17,230
Urinary Tract 22 | 16,678

Target Family

Non-IDG 12 | 12,091
Transcription Factor 6 | 1,400
Enzyme 3 | 4,145
Epigenetic 1 | 242
TF/Epigenetic 1 | 38

GO Component

nuclear chromosome 23 | 23
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Meiotic recombination protein SPO11 SPO11 Tbio Non-IDG -2.33263 208.9 148
Protein polybromo-1 PBRM1 Tchem TF/Epigenetic -1.92500 84.6 97
Heterogeneous nuclear ribonucleoprotein U HNRNPU Tbio Non-IDG -2.33813 207.8 169
Telomeric repeat-binding factor 2-interacting protein 1 TERF2IP Tchem Non-IDG -0.75509 5.75 308
High mobility group protein HMGI-C HMGA2 Tbio Transcription Factor -3.26377 1794.1 235
Histone deacetylase 8 HDAC8 Tclin Epigenetic -2.41838 263.5 487
DNA repair-scaffolding protein SPIDR Tbio Non-IDG -0.75333 5.57 24
Exosome complex component RRP45 EXOSC9 Tbio Enzyme -1.17714 13.5 92
Core histone macro-H2A.1 H2AFY Tbio Non-IDG -1.78572 69.6 95
Structural maintenance of chromosomes protein 2 SMC2 Tbio Non-IDG -0.69216 5.13 188