Development Level

Tbio 134 | 11,445
Tchem 29 | 1,598
Tdark 13 | 6,588
Tclin 8 | 613

IMPC Phenotype

preweaning lethality, complete... 18 | 979
preweaning lethality, incomple... 10 | 499
abnormal behavior 7 | 298
decreased total body fat amoun... 6 | 207
embryonic lethality prior to t... 6 | 278
decreased vertical activity 4 | 208
embryonic lethality prior to o... 4 | 239
increased bone mineral content 4 | 108
abnormal embryo size 3 | 220
abnormal gait 3 | 69
abnormal seminal vesicle morph... 3 | 114
decreased blood urea nitrogen ... 3 | 51
decreased circulating choleste... 3 | 93
enlarged heart 3 | 210
hypoactivity 3 | 132
increased lean body mass 3 | 172
small spleen 3 | 19
abnormal bone structure 2 | 187
abnormal coat appearance 2 | 31
abnormal craniofacial morpholo... 2 | 33
abnormal kidney morphology 2 | 65
abnormal spleen morphology 2 | 55
cardiovascular system phenotyp... 2 | 36
decreased caudal vertebrae num... 2 | 53
decreased circulating alkaline... 2 | 46
decreased circulating glucose ... 2 | 126
decreased grip strength 2 | 116
decreased leukocyte cell numbe... 2 | 73
edema 2 | 59
embryonic growth retardation 2 | 106
hyperactivity 2 | 148
impaired glucose tolerance 2 | 75
improved glucose tolerance 2 | 79
increased bone mineral density 2 | 72
increased circulating HDL chol... 2 | 80
increased circulating alkaline... 2 | 122
increased circulating choleste... 2 | 66
increased circulating triglyce... 2 | 42
increased hemoglobin content 2 | 45
increased startle reflex 2 | 112
prenatal lethality prior to he... 2 | 87
small testis 2 | 58
abnormal cranium morphology 1 | 36
abnormal ear morphology 1 | 9
abnormal embryo turning 1 | 31
abnormal eye morphology 1 | 68
abnormal facial morphology 1 | 17
abnormal heart left ventricle ... 1 | 16
abnormal lens morphology 1 | 81
abnormal locomotor behavior 1 | 24
abnormal neural tube closure 1 | 46
abnormal neural tube morpholog... 1 | 12
abnormal pancreas morphology 1 | 13
abnormal retina morphology 1 | 71
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal testis morphology 1 | 43
abnormal tooth morphology 1 | 24
absent pinna reflex 1 | 23
cataract 1 | 92
decreased body length 1 | 101
decreased bone mineral content 1 | 151
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating bilirubi... 1 | 19
decreased circulating creatine... 1 | 4
decreased circulating creatini... 1 | 39
decreased circulating fructosa... 1 | 30
decreased circulating insulin ... 1 | 76
decreased circulating serum al... 1 | 82
decreased circulating triglyce... 1 | 79
decreased fasted circulating g... 1 | 65
decreased heart weight 1 | 27
decreased hemoglobin content 1 | 68
decreased lean body mass 1 | 135
decreased prepulse inhibition 1 | 82
decreased spleen weight 1 | 10
decreased startle reflex 1 | 75
enlarged lymph nodes 1 | 37
female infertility 1 | 60
hemorrhage 1 | 23
hydrometra 1 | 53
impaired righting response 1 | 26
increased body temperature 1 | 9
increased body weight 1 | 25
increased circulating chloride... 1 | 41
increased circulating creatine... 1 | 5
increased circulating glycerol... 1 | 9
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular hem... 1 | 96
increased prepulse inhibition 1 | 32
limb grasping 1 | 41
lordosis 1 | 1
pallor 1 | 34
persistence of hyaloid vascula... 1 | 33
short tibia 1 | 97
small kidney 1 | 16
thin ventricular wall 1 | 24
tremors 1 | 39
vertebral transformation 1 | 12

Disease

Carcinoma 122 | 11,493
ovarian cancer 113 | 8,520
osteosarcoma 105 | 7,950
psoriasis 94 | 6,694
glioblastoma 82 | 5,792
medulloblastoma, large-cell 82 | 6,241
lung cancer 81 | 4,740
Cancer 78 | 2,499
atypical teratoid / rhabdoid tumor 72 | 5,112
Breast cancer 68 | 3,578
group 3 medulloblastoma 67 | 4,104
malignant mesothelioma 58 | 3,232
primitive neuroectodermal tumor 55 | 3,035
ependymoma 53 | 4,679
invasive ductal carcinoma 45 | 2,951
lung adenocarcinoma 40 | 2,716
non-small cell lung cancer 40 | 2,890
adult high grade glioma 39 | 3,801
Kidney cancer 36 | 2,613
intraductal papillary-mucinous neoplasm (IPMN) 36 | 3,291
oligodendroglioma 33 | 2,850
Multiple myeloma 31 | 1,332
astrocytoma 31 | 1,146
pancreatic cancer 30 | 2,398
breast carcinoma 29 | 1,638
ductal carcinoma in situ 29 | 1,745
intraductal papillary-mucinous carcinoma (IPMC) 29 | 2,989
subependymal giant cell astrocytoma 29 | 2,287
intraductal papillary-mucinous adenoma (IPMA) 28 | 2,955
Astrocytoma, Pilocytic 27 | 3,081
Intellectual disability 27 | 1,016
Schizophrenia 27 | 1,160
Rheumatoid arthritis 25 | 1,191
group 4 medulloblastoma 25 | 1,855
astrocytic glioma 24 | 2,597
ulcerative colitis 24 | 1,819
juvenile dermatomyositis 23 | 1,187
lung carcinoma 23 | 2,843
colon cancer 22 | 1,478
interstitial cystitis 22 | 2,312
pancreatic ductal adenocarcinoma liver metastasis 22 | 1,962
pediatric high grade glioma 22 | 1,064
tuberculosis 22 | 2,010
adrenocortical carcinoma 21 | 1,428
pituitary cancer 21 | 1,972
Pick disease 20 | 1,894
diabetes mellitus 20 | 1,728
acute quadriplegic myopathy 19 | 1,158
dermatomyositis 19 | 966
Breast Neoplasms 18 | 445
Epilepsy 18 | 792
Mammary Neoplasms 18 | 425
Muscle hypotonia 18 | 571
Dull intelligence 17 | 645
Low intelligence 17 | 645
Mental Retardation 17 | 645
Mental deficiency 17 | 645
Poor school performance 17 | 645
Short stature 17 | 531
Atopic dermatitis 16 | 952
Autosomal recessive predisposition 16 | 1,442
Bipolar Disorder 16 | 666
Cryptorchidism 16 | 296
Endometriosis 16 | 540
Seizures 16 | 596
nasopharyngeal carcinoma 16 | 1,058
spina bifida 16 | 1,074
acute myeloid leukemia 15 | 783
Acquired scoliosis 14 | 281
Curvature of spine 14 | 282
Prostatic Neoplasms 14 | 495
Small head 14 | 374
Waldenstrons macroglobulinemia 14 | 765
Cleft Palate 13 | 271
Vascular disease 13 | 319
medulloblastoma 13 | 720
primary pancreatic ductal adenocarcinoma 13 | 1,109
Adenocarcinoma 12 | 122
Carcinoma, Hepatocellular 12 | 228
Cognitive delay 12 | 608
Global developmental delay 12 | 608
Mental and motor retardation 12 | 608
hearing impairment 12 | 199
non-small cell lung carcinoma 12 | 317
pancreatic carcinoma 12 | 562
Broad flat nasal bridge 11 | 236
Deafness 11 | 198
Hearing Loss, Partial 11 | 185
Liver carcinoma 11 | 240
Lung Neoplasms 11 | 232
Melanoma 11 | 711
Nasal bridge wide 11 | 236
Obesity 11 | 678
Stomach Neoplasms 11 | 300
Strabismus 11 | 270
aldosterone-producing adenoma 11 | 665
cystic fibrosis 11 | 1,696
esophageal adenocarcinoma 11 | 737
gastric cancer 11 | 459
primary Sjogren syndrome 11 | 735

Tissue

Endocrine System 183 | 18,159
Digestive Tract 181 | 17,369
Skin and soft tissues 180 | 17,230
Female tissues 178 | 17,400
Blood and immune system 177 | 16,909
Male tissues 177 | 17,142
Nervous System 176 | 16,725
Liver and Pancreas 174 | 16,750
Urinary Tract 173 | 16,678
Respiratory system 171 | 16,393
Cardiovascular System 170 | 15,192

Target Family

Non-IDG 75 | 12,091
Transcription Factor 65 | 1,400
Epigenetic 23 | 242
Enzyme 9 | 4,145
Nuclear Receptor 9 | 48
TF/Epigenetic 2 | 38
Kinase 1 | 634

GO Component

nuclear chromatin 184 | 184
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Histone H2A type 1-A HIST1H2AA Tbio Non-IDG -0.84480 8.19 69
Krueppel-like factor 2 KLF2 Tbio Transcription Factor -2.30630 216.2 308
Methyl-CpG-binding domain protein 3 MBD3 Tbio Transcription Factor -0.85800 7.92 309
Transcription factor PU.1 SPI1 Tbio Transcription Factor -3.05079 1139.0 397
Forkhead box protein D3 FOXD3 Tbio Transcription Factor -2.69659 482.7 180
Mini-chromosome maintenance complex-binding protein MCMBP Tbio Non-IDG -0.65233 5.60 92
Chromodomain-helicase-DNA-binding protein 4 CHD4 Tbio Epigenetic -2.22229 159.7 203
Chromobox protein homolog 8 CBX8 Tchem Epigenetic -2.27537 183.4 505
Histone H1.3 HIST1H1D Tbio Non-IDG -1.83212 63.8 66
Histone H1.5 HIST1H1B Tbio Non-IDG -2.13224 134.1 103