Development Level

Tbio 204 | 11,445
Tchem 63 | 1,598
Tclin 43 | 613
Tdark 15 | 6,588

Collection

Ion Channel: IDG Consortium (T... 3 | 99
RFA-RM-18-021 3 | 328
Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

preweaning lethality, complete... 21 | 979
preweaning lethality, incomple... 15 | 499
abnormal behavior 12 | 298
decreased total body fat amoun... 11 | 207
decreased lean body mass 10 | 135
embryonic lethality prior to o... 8 | 239
decreased grip strength 7 | 116
impaired glucose tolerance 7 | 75
increased circulating alkaline... 7 | 122
increased total body fat amoun... 7 | 134
decreased vertical activity 6 | 208
embryonic lethality prior to t... 6 | 278
increased lean body mass 6 | 172
abnormal bone structure 5 | 187
decreased bone mineral content 5 | 151
decreased circulating choleste... 5 | 93
decreased circulating glucose ... 5 | 126
decreased circulating serum al... 5 | 82
decreased fasted circulating g... 5 | 65
hyperactivity 5 | 148
hypoactivity 5 | 132
abnormal embryo size 4 | 220
abnormal locomotor behavior 4 | 24
abnormal retina morphology 4 | 71
abnormal testis morphology 4 | 43
cataract 4 | 92
decreased body weight 4 | 161
decreased bone mineral density 4 | 126
decreased circulating alkaline... 4 | 46
decreased circulating amylase ... 4 | 28
decreased startle reflex 4 | 75
edema 4 | 59
increased fasted circulating g... 4 | 76
increased or absent threshold ... 4 | 101
prenatal lethality prior to he... 4 | 87
prolonged QT interval 4 | 38
prolonged ST segment 4 | 36
short tibia 4 | 97
abnormal gait 3 | 69
abnormal lens morphology 3 | 81
abnormal sleep behavior 3 | 70
decreased blood urea nitrogen ... 3 | 51
decreased circulating HDL chol... 3 | 68
decreased circulating creatini... 3 | 39
decreased circulating triglyce... 3 | 79
decreased heart weight 3 | 27
hemorrhage 3 | 23
improved glucose tolerance 3 | 79
increased bone mineral content 3 | 108
increased bone mineral density 3 | 72
increased circulating chloride... 3 | 41
increased circulating sodium l... 3 | 71
abnormal behavioral response t... 2 | 66
abnormal coat-hair pigmentatio... 2 | 64
abnormal epididymis morphology 2 | 42
abnormal heart morphology 2 | 162
abnormal seminal vesicle morph... 2 | 114
cyanosis 2 | 7
decreased basophil cell number 2 | 16
decreased body length 2 | 101
decreased caudal vertebrae num... 2 | 53
decreased circulating LDL chol... 2 | 38
decreased circulating alanine ... 2 | 47
decreased circulating fructosa... 2 | 30
decreased circulating glycerol... 2 | 16
decreased circulating insulin ... 2 | 76
decreased circulating phosphat... 2 | 27
decreased circulating total pr... 2 | 49
decreased eosinophil cell numb... 2 | 24
decreased exploration in new e... 2 | 11
decreased lymphocyte cell numb... 2 | 83
decreased neutrophil cell numb... 2 | 42
decreased prepulse inhibition 2 | 82
decreased pulmonary respirator... 2 | 5
decreased red blood cell distr... 2 | 41
enlarged heart 2 | 210
enlarged lymph nodes 2 | 37
enlarged stomach 2 | 2
impaired pupillary reflex 2 | 26
increased blood urea nitrogen ... 2 | 48
increased circulating LDL chol... 2 | 13
increased circulating amylase ... 2 | 25
increased circulating choleste... 2 | 66
increased circulating triglyce... 2 | 42
increased heart rate 2 | 23
increased mean corpuscular hem... 2 | 96
increased red blood cell distr... 2 | 34
increased spleen weight 2 | 10
pallor 2 | 34
persistence of hyaloid vascula... 2 | 33
prenatal lethality 2 | 28
small superior vagus ganglion 2 | 74
small testis 2 | 58
small thymus 2 | 16
thrombocytopenia 2 | 56
tremors 2 | 39
trunk curl 2 | 16
increased anti-nuclear antigen... 1 | 19
increased circulating iron lev... 1 | 30
increased heart weight 1 | 62

Disease

Carcinoma 221 | 11,493
glioblastoma 169 | 5,792
medulloblastoma, large-cell 156 | 6,241
atypical teratoid / rhabdoid tumor 152 | 5,112
ovarian cancer 152 | 8,520
ependymoma 139 | 4,679
osteosarcoma 139 | 7,950
psoriasis 138 | 6,694
adult high grade glioma 125 | 3,801
Astrocytoma, Pilocytic 120 | 3,081
group 3 medulloblastoma 119 | 4,104
lung cancer 112 | 4,740
oligodendroglioma 107 | 2,850
primitive neuroectodermal tumor 90 | 3,035
Kidney cancer 88 | 2,613
Schizophrenia 87 | 1,160
malignant mesothelioma 87 | 3,232
astrocytic glioma 86 | 2,597
Cancer 85 | 2,499
subependymal giant cell astrocytoma 85 | 2,287
Breast cancer 77 | 3,578
lung carcinoma 77 | 2,843
Pick disease 67 | 1,894
intraductal papillary-mucinous carcinoma (IPMC) 64 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 63 | 2,955
invasive ductal carcinoma 63 | 2,951
pituitary cancer 62 | 1,972
intraductal papillary-mucinous neoplasm (IPMN) 60 | 3,291
Bipolar Disorder 54 | 666
Epilepsy 52 | 792
non-small cell lung cancer 52 | 2,890
pancreatic cancer 51 | 2,398
interstitial cystitis 50 | 2,312
lung adenocarcinoma 49 | 2,716
Alzheimer's disease 48 | 658
colon cancer 47 | 1,478
diabetes mellitus 45 | 1,728
Intellectual disability 44 | 1,016
group 4 medulloblastoma 44 | 1,855
Autosomal recessive predisposition 43 | 1,442
cystic fibrosis 43 | 1,696
tuberculosis 43 | 2,010
ulcerative colitis 42 | 1,819
Depressive disorder 41 | 409
Parkinson's disease 39 | 392
Neurodegenerative disease 38 | 414
astrocytoma 37 | 1,146
Seizures 34 | 596
cutaneous lupus erythematosus 30 | 1,057
ductal carcinoma in situ 30 | 1,745
Down syndrome 29 | 499
Mental Depression 29 | 333
Autistic Disorder 28 | 364
Liver cancer 28 | 604
Obesity 28 | 678
pancreatic ductal adenocarcinoma liver metastasis 28 | 1,962
Cognitive delay 27 | 608
Global developmental delay 27 | 608
Mental and motor retardation 27 | 608
pediatric high grade glioma 27 | 1,064
Dull intelligence 26 | 645
Low intelligence 26 | 645
Melanoma 26 | 711
Mental Retardation 26 | 645
Mental deficiency 26 | 645
Poor school performance 26 | 645
acute quadriplegic myopathy 26 | 1,158
Liver Cirrhosis, Experimental 25 | 769
Multiple myeloma 25 | 1,332
Vascular disease 25 | 319
adrenocortical carcinoma 25 | 1,428
breast carcinoma 25 | 1,638
Rheumatoid arthritis 24 | 1,191
Alcoholic Intoxication, Chronic 23 | 289
Major Depressive Disorder 23 | 301
Skin cancer 23 | 469
Dementia 22 | 175
Prostatic Neoplasms 22 | 495
juvenile dermatomyositis 22 | 1,187
Mood Disorders 21 | 184
Toxic encephalopathy 21 | 141
active Crohn's disease 21 | 922
Hypertension 20 | 396
Muscle hypotonia 20 | 571
aldosterone-producing adenoma 20 | 665
gastric carcinoma 20 | 807
nasopharyngeal carcinoma 20 | 1,058
spina bifida 20 | 1,074
Amyotrophic lateral sclerosis 19 | 451
primary pancreatic ductal adenocarcinoma 19 | 1,109
Duchenne muscular dystrophy 18 | 601
Hypertensive disease 18 | 292
Kidney disease 18 | 430
Endometrial cancer 17 | 311
Endometriosis 17 | 540
esophageal adenocarcinoma 17 | 737
Short stature 16 | 531
non primary Sjogren syndrome sicca 16 | 891
pancreatic carcinoma 16 | 562
progressive supranuclear palsy 16 | 676

Tissue

Endocrine System 321 | 18,159
Female tissues 313 | 17,400
Nervous System 312 | 16,725
Digestive Tract 310 | 17,369
Male tissues 309 | 17,142
Skin and soft tissues 309 | 17,230
Urinary Tract 306 | 16,678
Liver and Pancreas 305 | 16,750
Blood and immune system 300 | 16,909
Respiratory system 296 | 16,393
Cardiovascular System 276 | 15,192

Target Family

Non-IDG 181 | 12,091
Enzyme 59 | 4,145
Ion Channel 32 | 344
Kinase 24 | 634
Transporter 11 | 473
GPCR 10 | 408
Transcription Factor 7 | 1,400
Nuclear Receptor 1 | 48

GO Component

neuronal cell body 325 | 325
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Tubulin beta-4A chain TUBB4A Tclin Non-IDG -2.98371 896.1 90
Nuclear mitotic apparatus protein 1 NUMA1 Tbio Non-IDG -2.76544 575.8 235
Cytoglobin CYGB Tbio Non-IDG -3.10582 1269.7 202
Calbindin CALB1 Tbio Non-IDG -3.31956 2149.9 287
Polypyrimidine tract-binding protein 2 PTBP2 Tbio Non-IDG -2.05261 113.3 151
Sodium-coupled neutral amino acid transporter 2 SLC38A2 Tbio Transporter -1.98482 96.5 91
DNA-directed RNA polymerase II subunit GRINL1A POLR2M Tbio Enzyme -0.79840 17.1 54
RNA-binding protein 8A RBM8A Tbio Non-IDG -3.16448 1415.1 94
Connector enhancer of kinase suppressor of ras 2 CNKSR2 Tbio Enzyme -1.11551 14.5 71
T-box transcription factor TBX21 TBX21 Tbio Transcription Factor -2.95359 868.5 480