Development Level

Tbio 155 | 11,651
Tchem 45 | 1,388
Tclin 31 | 612
Tdark 4 | 6,593

Collection

GPCR: IDG Consortium (Targets) 4 | 126
Kinase: IDG Consortium (Target... 2 | 125
Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

preweaning lethality, complete... 17 | 979
preweaning lethality, incomple... 12 | 499
embryonic lethality prior to t... 7 | 278
abnormal behavior 6 | 298
abnormal bone structure 6 | 187
abnormal embryo size 6 | 220
abnormal heart morphology 6 | 162
decreased total body fat amoun... 6 | 207
embryonic lethality prior to o... 6 | 239
decreased vertical activity 5 | 208
enlarged heart 5 | 210
abnormal coat-hair pigmentatio... 4 | 64
decreased lean body mass 4 | 135
short tibia 4 | 97
abnormal retina morphology 3 | 71
decreased bone mineral content 3 | 151
decreased circulating choleste... 3 | 93
embryonic growth retardation 3 | 106
hemorrhage 3 | 23
hyperactivity 3 | 148
increased erythrocyte cell num... 3 | 39
increased fasted circulating g... 3 | 76
increased neutrophil cell numb... 3 | 46
small superior vagus ganglion 3 | 74
abnormal cornea morphology 2 | 31
abnormal digit morphology 2 | 10
abnormal facial morphology 2 | 17
abnormal neural tube closure 2 | 46
abnormal seminal vesicle morph... 2 | 114
abnormal testis morphology 2 | 43
corneal opacity 2 | 32
decreased body weight 2 | 161
decreased bone mineral density 2 | 126
decreased caudal vertebrae num... 2 | 53
decreased circulating glucose ... 2 | 126
fused cornea and lens 2 | 5
impaired glucose tolerance 2 | 75
increased circulating chloride... 2 | 41
increased circulating sodium l... 2 | 71
increased or absent threshold ... 2 | 101
increased prepulse inhibition 2 | 32
increased total body fat amoun... 2 | 134
pale yolk sac 2 | 25
pallor 2 | 34
prolonged QT interval 2 | 38
prolonged ST segment 2 | 36
small testis 2 | 58
tremors 2 | 39
abnormal behavioral response t... 1 | 66
abnormal craniofacial morpholo... 1 | 33
abnormal cranium morphology 1 | 36
abnormal embryo turning 1 | 31
abnormal epididymis morphology 1 | 42
abnormal gait 1 | 69
abnormal locomotor behavior 1 | 24
abnormal lung morphology 1 | 26
abnormal motor capabilities-co... 1 | 5
abnormal neural tube morpholog... 1 | 12
abnormal sleep behavior 1 | 70
abnormal spleen morphology 1 | 55
abnormal vitelline vasculature... 1 | 6
anophthalmia 1 | 33
decreased blood urea nitrogen ... 1 | 51
decreased circulating creatine... 1 | 4
decreased circulating creatini... 1 | 39
decreased circulating iron lev... 1 | 32
decreased circulating phosphat... 1 | 27
decreased circulating potassiu... 1 | 20
decreased circulating serum al... 1 | 82
decreased fasted circulating g... 1 | 65
decreased neutrophil cell numb... 1 | 42
decreased prepulse inhibition 1 | 82
decreased red blood cell distr... 1 | 41
decreased total retina thickne... 1 | 17
edema 1 | 59
hydrometra 1 | 53
hypoactivity 1 | 132
impaired pupillary reflex 1 | 26
increased blood uric acid leve... 1 | 5
increased body weight 1 | 25
increased bone mineral content 1 | 108
increased circulating alkaline... 1 | 122
increased circulating amylase ... 1 | 25
increased circulating bilirubi... 1 | 16
increased circulating calcium ... 1 | 34
increased circulating creatine... 1 | 5
increased circulating glucose ... 1 | 24
increased circulating potassiu... 1 | 29
increased circulating serum al... 1 | 22
increased circulating total pr... 1 | 28
increased hematocrit 1 | 46
increased lean body mass 1 | 172
increased monocyte cell number 1 | 63
increased startle reflex 1 | 112
increased vertical activity 1 | 24
limb grasping 1 | 41
microphthalmia 1 | 26
persistence of hyaloid vascula... 1 | 33
scaly skin 1 | 4
thick skin 1 | 4

Disease

Carcinoma 171 | 11,493
medulloblastoma, large-cell 129 | 6,241
glioblastoma 126 | 5,792
atypical teratoid / rhabdoid tumor 122 | 5,112
ovarian cancer 118 | 8,520
adult high grade glioma 112 | 3,801
ependymoma 111 | 4,679
osteosarcoma 98 | 7,950
group 3 medulloblastoma 96 | 4,104
oligodendroglioma 93 | 2,850
psoriasis 92 | 6,694
Astrocytoma, Pilocytic 90 | 3,081
astrocytic glioma 81 | 2,597
lung cancer 77 | 4,740
primitive neuroectodermal tumor 70 | 3,035
malignant mesothelioma 65 | 3,232
lung carcinoma 62 | 2,843
Breast cancer 61 | 3,578
subependymal giant cell astrocytoma 61 | 2,287
Schizophrenia 60 | 1,160
Cancer 58 | 2,499
Kidney cancer 56 | 2,613
Pick disease 54 | 1,894
intraductal papillary-mucinous adenoma (IPMA) 50 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 50 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 49 | 3,291
non-small cell lung cancer 46 | 2,890
invasive ductal carcinoma 45 | 2,951
lung adenocarcinoma 45 | 2,716
Intellectual disability 44 | 1,016
Bipolar Disorder 37 | 666
interstitial cystitis 36 | 2,312
pituitary cancer 36 | 1,972
Epilepsy 34 | 792
pancreatic cancer 34 | 2,398
ulcerative colitis 34 | 1,819
tuberculosis 32 | 2,010
Depressive disorder 30 | 409
Parkinson's disease 29 | 392
astrocytoma 29 | 1,146
group 4 medulloblastoma 29 | 1,855
Alzheimer's disease 28 | 658
Autosomal recessive predisposition 28 | 1,442
Seizures 28 | 596
cystic fibrosis 28 | 1,696
Mental Depression 27 | 333
breast carcinoma 27 | 1,638
Autistic Disorder 26 | 364
colon cancer 26 | 1,478
ductal carcinoma in situ 26 | 1,745
Alcoholic Intoxication, Chronic 25 | 289
diabetes mellitus 25 | 1,728
Dull intelligence 23 | 645
Low intelligence 23 | 645
Major Depressive Disorder 23 | 301
Mental Retardation 23 | 645
Mental deficiency 23 | 645
Obesity 23 | 678
Poor school performance 23 | 645
Multiple myeloma 21 | 1,332
acute quadriplegic myopathy 20 | 1,158
adrenocortical carcinoma 20 | 1,428
primary pancreatic ductal adenocarcinoma 20 | 1,109
spina bifida 20 | 1,074
Amyotrophic lateral sclerosis 19 | 451
Liver cancer 19 | 604
Neurodegenerative disease 19 | 414
Toxic encephalopathy 19 | 141
Unipolar Depression 19 | 250
Attention deficit hyperactivity disorder 17 | 278
Liver Cirrhosis, Experimental 17 | 769
Rheumatoid arthritis 17 | 1,191
Melanoma 16 | 711
dermatomyositis 16 | 966
non primary Sjogren syndrome sicca 16 | 891
Atopic dermatitis 15 | 952
Vascular disease 15 | 319
cutaneous lupus erythematosus 15 | 1,057
nasopharyngeal carcinoma 15 | 1,058
pancreatic ductal adenocarcinoma liver metastasis 15 | 1,962
Breast Neoplasms 14 | 445
Cognitive delay 14 | 608
Global developmental delay 14 | 608
Mental and motor retardation 14 | 608
Mood Disorders 14 | 184
acute myeloid leukemia 14 | 783
Alcohol dependence 13 | 107
Down syndrome 13 | 499
Mammary Neoplasms 13 | 425
Skin cancer 13 | 469
aldosterone-producing adenoma 13 | 665
fibroadenoma 13 | 559
Endometrial cancer 12 | 311
Muscle hypotonia 12 | 571
Status Epilepticus 12 | 98
autosomal dominant Emery-Dreifuss muscular dystrophy 12 | 510
juvenile dermatomyositis 12 | 1,187
Asthma 11 | 385
Short stature 11 | 531
progressive supranuclear palsy 11 | 676

Tissue

Endocrine System 232 | 18,159
Nervous System 229 | 16,725
Female tissues 223 | 17,400
Skin and soft tissues 221 | 17,230
Blood and immune system 220 | 16,909
Digestive Tract 220 | 17,369
Liver and Pancreas 218 | 16,750
Male tissues 218 | 17,142
Urinary Tract 212 | 16,678
Respiratory system 211 | 16,393
Cardiovascular System 194 | 15,192

Target Family

Non-IDG 121 | 12,091
Enzyme 42 | 4,145
GPCR 24 | 408
Kinase 18 | 634
Transporter 11 | 473
Ion Channel 9 | 344
Transcription Factor 6 | 1,400
Epigenetic 4 | 242

GO Component

neuron projection 235 | 235
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Stonin-2 STON2 Tbio Non-IDG -1.43585 30.0 11
Cytoplasmic FMR1-interacting protein 1 CYFIP1 Tbio Non-IDG -1.46134 28.5 64
4-aminobutyrate aminotransferase, mitochondrial ABAT Tclin Enzyme -2.02391 104.3 204
Sodium-dependent serotonin transporter SLC6A4 Tclin Transporter -3.63283 4453.8 245
Voltage-dependent calcium channel gamma-2 subunit CACNG2 Tbio Ion Channel -1.92203 89.6 173
Ly6/PLAUR domain-containing protein 6 LYPD6 Tbio Non-IDG -0.61559 4.87 35
Phosphatidylinositol 4-kinase type 2-alpha PI4K2A Tbio Kinase -2.88003 745.1 146
Synaptotagmin-11 SYT11 Tbio Non-IDG -1.00759 12.5 125
Vacuolar protein sorting-associated protein 35 VPS35 Tbio Non-IDG -2.02621 104.1 124
Copine-5 CPNE5 Tbio Non-IDG -0.45967 3.10 91