Development Level

Tbio 144 | 10,625
Tchem 49 | 1,890
Tclin 31 | 602
Tdark 5 | 7,003

Collection

Eligible non-olfactory GPCR Proteins 5 | 143
Eligible Kinase Proteins 2 | 134

IMPC Term

preweaning lethality, complete... 10 | 633
preweaning lethality, incomple... 7 | 260
abnormal behavior 5 | 226
abnormal embryo size 5 | 112
decreased total body fat amoun... 5 | 186
decreased bone mineral content 4 | 157
embryonic lethality prior to t... 4 | 187
abnormal coat/hair pigmentatio... 3 | 54
decreased body weight 3 | 174
decreased circulating alanine ... 3 | 53
embryonic lethality prior to o... 3 | 148
increased grip strength 3 | 83
thrombocytopenia 3 | 46
abnormal bone structure 2 | 131
abnormal forebrain development 2 | 18
abnormal gait 2 | 51
abnormal hindbrain development 2 | 24
abnormal neural tube closure 2 | 37
abnormal retinal pigmentation 2 | 61
decreased circulating choleste... 2 | 85
decreased lean body mass 2 | 195
enlarged heart 2 | 111
hyperactivity 2 | 108
increased circulating calcium ... 2 | 32
increased circulating chloride... 2 | 43
increased circulating sodium l... 2 | 71
increased fasted circulating g... 2 | 68
increased mean corpuscular hem... 2 | 93
small superior vagus ganglion 2 | 20
tremors 2 | 34
abnormal behavioral response t... 1 | 52
abnormal coat appearance 1 | 25
abnormal digit morphology 1 | 13
abnormal embryo turning 1 | 15
abnormal eye morphology 1 | 38
abnormal eye size 1 | 11
abnormal facial morphology 1 | 9
abnormal femur morphology 1 | 14
abnormal head shape 1 | 4
abnormal heart morphology 1 | 51
abnormal limb morphology 1 | 7
abnormal midbrain development 1 | 22
abnormal motor capabilities/co... 1 | 4
abnormal posture 1 | 5
abnormal retina morphology 1 | 100
abnormal skin appearance 1 | 8
abnormal sleep behavior 1 | 63
abnormal snout morphology 1 | 18
abnormal spleen morphology 1 | 36
abnormal tail movements 1 | 12
abnormal tooth morphology 1 | 24
absent teeth 1 | 4
anophthalmia 1 | 20
craniofacial phenotype 1 | 9
cyanosis 1 | 6
decreased caudal vertebrae num... 1 | 49
decreased circulating iron lev... 1 | 25
decreased circulating potassiu... 1 | 17
decreased effector memory CD4-... 1 | 6
decreased fasted circulating g... 1 | 49
decreased gamma-delta T cell n... 1 | 18
decreased granulocyte number 1 | 8
decreased grip strength 1 | 123
decreased lumbar vertebrae num... 1 | 62
decreased monocyte cell number 1 | 28
decreased total retina thickne... 1 | 20
embryonic growth retardation 1 | 28
fused cornea and lens 1 | 4
hemorrhage 1 | 12
herniated abdominal wall 1 | 4
hydrops fetalis 1 | 22
impaired glucose tolerance 1 | 52
increased B cell number 1 | 23
increased T cell number 1 | 15
increased blood uric acid leve... 1 | 5
increased body weight 1 | 42
increased bone mineral density 1 | 52
increased circulating alkaline... 1 | 119
increased circulating amylase ... 1 | 13
increased circulating bilirubi... 1 | 16
increased circulating glucose ... 1 | 16
increased circulating potassiu... 1 | 31
increased circulating serum al... 1 | 25
increased circulating total pr... 1 | 20
increased erythrocyte cell num... 1 | 26
increased granulocyte number 1 | 8
increased heart rate variabili... 1 | 4
increased mature B cell number 1 | 12
increased mean corpuscular hem... 1 | 25
increased rib number 1 | 41
increased sacral vertebrae num... 1 | 62
increased startle reflex 1 | 38
increased total body fat amoun... 1 | 57
limb grasping 1 | 35
microphthalmia 1 | 15
pale yolk sac 1 | 12
prenatal lethality prior to he... 1 | 64
short tibia 1 | 82
small adrenal glands 1 | 15
straub tail 1 | 26

Disease

medulloblastoma, large-cell 128 | 6,234
glioblastoma 121 | 5,572
ovarian cancer 116 | 8,484
atypical teratoid / rhabdoid tumor 103 | 4,369
osteosarcoma 94 | 7,933
psoriasis 93 | 6,685
pilocytic astrocytoma 90 | 3,086
oligodendroglioma 89 | 2,849
lung cancer 73 | 4,466
pediatric high grade glioma 69 | 2,712
primitive neuroectodermal tumor 67 | 3,031
lung carcinoma 64 | 2,844
subependymal giant cell astrocytoma 60 | 2,287
malignant mesothelioma 58 | 3,162
astrocytic glioma 56 | 2,241
ependymoma 56 | 2,514
Cancer 55 | 2,346
astrocytoma 55 | 1,493
adult high grade glioma 54 | 2,148
Pick disease 53 | 1,893
Breast cancer 50 | 3,094
intraductal papillary-mucinous adenoma (IPMA) 49 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 49 | 2,988
Carcinoma 48 | 2,147
non-small cell lung cancer 47 | 2,798
intraductal papillary-mucinous neoplasm (IPMN) 46 | 3,289
invasive ductal carcinoma 44 | 2,950
lung adenocarcinoma 43 | 2,713
posterior fossa group A ependymoma 40 | 1,511
group 4 medulloblastoma 39 | 1,875
medulloblastoma 38 | 1,524
group 3 medulloblastoma 37 | 2,254
interstitial cystitis 35 | 2,299
pituitary cancer 34 | 1,972
ulcerative colitis 34 | 2,087
Schizophrenia 32 | 501
sonic hedgehog group medulloblastoma 30 | 1,482
pancreatic cancer 28 | 2,300
colon cancer 27 | 1,475
Alzheimer's disease 26 | 644
Intellectual disability 26 | 573
breast carcinoma 26 | 1,614
cystic fibrosis 26 | 1,665
ductal carcinoma in situ 26 | 1,745
Autistic Disorder 24 | 320
Parkinson's disease 24 | 364
tuberculosis 24 | 1,557
Epilepsy 23 | 346
posterior fossa group B ependymoma 23 | 1,530
Multiple myeloma 22 | 1,327
atypical teratoid/rhabdoid tumor 22 | 1,095
Obesity 21 | 616
Rheumatoid Arthritis 21 | 1,160
primary pancreatic ductal adenocarcinoma 20 | 1,271
adrenocortical carcinoma 19 | 1,427
diabetes mellitus 18 | 1,663
spina bifida 18 | 1,064
Toxic encephalopathy 17 | 131
acute quadriplegic myopathy 17 | 1,157
Amyotrophic Lateral Sclerosis 16 | 431
Neurodegenerative disease 16 | 383
cutaneous lupus erythematosus 16 | 1,056
nasopharyngeal carcinoma 16 | 1,056
non primary Sjogren syndrome sicca 16 | 840
Mammary Neoplasms 15 | 410
pancreatic ductal adenocarcinoma liver metastasis 15 | 1,795
Bipolar Disorder 14 | 266
aldosterone-producing adenoma 14 | 664
dermatomyositis 14 | 933
Atopic dermatitis 13 | 944
Waldenstrons macroglobulinemia 13 | 765
fibroadenoma 13 | 557
Alcohol dependence 12 | 107
Down syndrome 12 | 548
Seizures 12 | 95
acute myeloid leukemia 12 | 780
juvenile dermatomyositis 12 | 1,189
Chronic Lymphocytic Leukemia 11 | 242
Status Epilepticus 11 | 85
Vascular disease 11 | 281
autosomal dominant Emery-Dreifuss muscular dystrophy 11 | 499
gastric carcinoma 11 | 832
progressive supranuclear palsy 11 | 674
Attention deficit hyperactivity disorder 10 | 156
Cerebrovascular disease 10 | 231
Lung Neoplasms 10 | 171
Major Depressive Disorder 10 | 106
glioblastoma multiforme 10 | 347
Adenoma 9 | 165
Asthma 9 | 349
Dementia 9 | 129
Duchenne muscular dystrophy 9 | 602
Endometriosis 9 | 535
Kidney disease 9 | 396
Melanoma 9 | 261
Cocaine-Related Disorders 8 | 88
Local anesthesia 8 | 40
Prostatic Neoplasms 8 | 471
hereditary spastic paraplegia 8 | 313
primary Sjogren syndrome 8 | 789

Tissue

Nervous System 229 | 18,561
Endocrine System 228 | 18,512
Digestive Tract 227 | 18,473
Female tissues 227 | 18,647
Urinary Tract 227 | 18,444
Liver and Pancreas 226 | 18,136
Skin and soft tissues 225 | 18,115
Cardiovascular System 223 | 17,958
Male tissues 222 | 17,969
Blood and immune system 220 | 17,995
Respiratory system 218 | 17,484

Target Family

Non-IDG 120 | 11,971
Enzyme 42 | 4,146
GPCR 23 | 406
Transporter 14 | 473
Kinase 11 | 634
Ion Channel 9 | 341
Epigenetic 5 | 242
Transcription Factor 5 | 1,400

GO Component

neuron projection 229 | 229
nucleus 5,107 | 5,107
cytoplasm 4,985 | 4,985
plasma membrane 4,118 | 4,118
integral component of membrane 3,679 | 3,679
cytosol 3,265 | 3,265
extracellular exosome 2,758 | 2,758
nucleoplasm 2,717 | 2,717
membrane 1,906 | 1,906
extracellular region 1,493 | 1,493
integral component of plasma m... 1,406 | 1,406
extracellular space 1,304 | 1,304
mitochondrion 1,231 | 1,231
Golgi apparatus 864 | 864
endoplasmic reticulum 859 | 859
endoplasmic reticulum membrane 848 | 848
nucleolus 815 | 815
Golgi membrane 659 | 659
perinuclear region of cytoplas... 611 | 611
cell surface 594 | 594
intracellular 548 | 548
intracellular membrane-bounded... 537 | 537
cell junction 451 | 451
mitochondrial inner membrane 425 | 425
centrosome 409 | 409
focal adhesion 383 | 383
protein complex 355 | 355
cytoskeleton 343 | 343
dendrite 329 | 329
mitochondrial matrix 322 | 322
cell-cell adherens junction 307 | 307
neuronal cell body 303 | 303
microtubule 294 | 294
lysosomal membrane 278 | 278
apical plasma membrane 277 | 277
proteinaceous extracellular ma... 244 | 244
nuclear membrane 218 | 218
early endosome 217 | 217
axon 214 | 214
lysosome 210 | 210
endosome 208 | 208
actin cytoskeleton 205 | 205
external side of plasma membra... 205 | 205
postsynaptic membrane 204 | 204
extracellular matrix 198 | 198
nuclear speck 197 | 197
membrane raft 196 | 196
endoplasmic reticulum lumen 192 | 192
transcription factor complex 184 | 184
endosome membrane 182 | 182
early endosome membrane 180 | 180
basolateral plasma membrane 174 | 174
nuclear chromatin 169 | 169
synapse 166 | 166
cell-cell junction 161 | 161
nuclear envelope 156 | 156
lamellipodium 153 | 153
mitochondrial outer membrane 148 | 148
blood microparticle 147 | 147
myelin sheath 144 | 144
postsynaptic density 144 | 144
cytoplasmic vesicle 143 | 143
microtubule organizing center 137 | 137
cytoplasmic, membrane-bounded ... 132 | 132
ER to Golgi transport vesicle ... 131 | 131
microtubule cytoskeleton 127 | 127
receptor complex 127 | 127
phagocytic vesicle membrane 126 | 126
cytoplasmic vesicle membrane 125 | 125
midbody 125 | 125
trans-Golgi network 124 | 124
cell cortex 119 | 119
cilium 118 | 118
late endosome 116 | 116
spindle 116 | 116
intracellular ribonucleoprotei... 114 | 114
vesicle 112 | 112
Z disc 110 | 110
bicellular tight junction 110 | 110
anchored component of membrane 109 | 109
growth cone 109 | 109
integral component of lumenal ... 108 | 108
late endosome membrane 107 | 107
endomembrane system 106 | 106
centriole 105 | 105
recycling endosome 104 | 104
spindle pole 104 | 104
perikaryon 103 | 103
integral component of endoplas... 101 | 101
intermediate filament 101 | 101
melanosome 101 | 101
chromosome 100 | 100
dendritic spine 99 | 99
ubiquitin ligase complex 99 | 99
peroxisome 98 | 98
nuclear matrix 97 | 97
PML body 94 | 94
Golgi lumen 93 | 93
keratin filament 93 | 93
trans-Golgi network membrane 92 | 92

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Proto-oncogene c-Fos FOS Tchem Transcription Factor -4.11560 13094.7 961
Testis-specific gene 10 protein TSGA10 Tbio Non-IDG -1.05563 13.1 82
Tyrosine-protein phosphatase non-receptor type 13 PTPN13 Tchem Enzyme -2.20613 177.9 120
Cytoplasmic polyadenylation element-binding protein 1 CPEB1 Tbio Non-IDG -2.20580 171.1 185
Neuropeptides B/W receptor type 1 NPBWR1 Tchem GPCR -1.34565 19.5 151
Neuropeptides B/W receptor type 2 NPBWR2 Tbio GPCR -1.14202 8.84 57
Cytoplasmic polyadenylation element-binding protein 3 CPEB3 Tbio Non-IDG -1.28920 20.4 75
Tumor necrosis factor receptor superfamily member 6 FAS Tbio Non-IDG -3.27492 2052.7 1794
Stathmin-2 STMN2 Tbio Non-IDG -1.95188 90.0 305
Syntaphilin SNPH Tbio Non-IDG -1.68074 54.2 98