Development Level

Tbio 35 | 11,445
Tchem 12 | 1,598
Tclin 7 | 613
Tdark 2 | 6,588

Collection

Ion Channel: IDG Consortium (T... 1 | 99

IMPC Phenotype

preweaning lethality, complete... 5 | 979
preweaning lethality, incomple... 3 | 499
abnormal sleep behavior 2 | 70
decreased total body fat amoun... 2 | 207
increased blood urea nitrogen ... 2 | 48
increased circulating HDL chol... 2 | 80
increased circulating choleste... 2 | 66
abnormal behavior 1 | 298
abnormal behavioral response t... 1 | 66
abnormal bone structure 1 | 187
abnormal ear morphology 1 | 9
abnormal hair growth 1 | 10
abnormal joint morphology 1 | 23
abnormal kidney morphology 1 | 65
abnormal lens morphology 1 | 81
abnormal limb morphology 1 | 13
abnormal sensory capabilities-... 1 | 8
abnormal tail morphology 1 | 25
abnormal testis morphology 1 | 43
absent startle reflex 1 | 24
brachydactyly 1 | 19
cataract 1 | 92
cyanosis 1 | 7
decreased basophil cell number 1 | 16
decreased circulating bilirubi... 1 | 19
decreased circulating fructosa... 1 | 30
decreased circulating glycerol... 1 | 16
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased erythrocyte cell num... 1 | 62
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular vol... 1 | 79
decreased prepulse inhibition 1 | 82
decreased spleen weight 1 | 10
decreased startle reflex 1 | 75
decreased vertical activity 1 | 208
edema 1 | 59
hemorrhage 1 | 23
hyperactivity 1 | 148
impaired glucose tolerance 1 | 75
impaired righting response 1 | 26
improved glucose tolerance 1 | 79
increased circulating amylase ... 1 | 25
increased circulating calcium ... 1 | 34
increased circulating creatini... 1 | 38
increased circulating phosphat... 1 | 26
increased circulating sodium l... 1 | 71
increased circulating triglyce... 1 | 42
increased grip strength 1 | 41
increased large unstained cell... 1 | 5
increased neutrophil cell numb... 1 | 46
increased red blood cell distr... 1 | 34
increased startle reflex 1 | 112
limb grasping 1 | 41
persistence of hyaloid vascula... 1 | 33
polycystic kidney 1 | 15
premature death 1 | 5
respiratory system phenotype 1 | 2
small testis 1 | 58
syndactyly 1 | 23
thrombocytosis 1 | 27
tremors 1 | 39

Disease

Carcinoma 42 | 11,493
medulloblastoma, large-cell 29 | 6,241
atypical teratoid / rhabdoid tumor 28 | 5,112
ovarian cancer 28 | 8,520
glioblastoma 27 | 5,792
osteosarcoma 27 | 7,950
ependymoma 24 | 4,679
group 3 medulloblastoma 23 | 4,104
adult high grade glioma 21 | 3,801
psoriasis 21 | 6,694
lung cancer 20 | 4,740
Astrocytoma, Pilocytic 18 | 3,081
Breast cancer 18 | 3,578
malignant mesothelioma 18 | 3,232
astrocytic glioma 17 | 2,597
Cancer 16 | 2,499
Schizophrenia 15 | 1,160
non-small cell lung cancer 15 | 2,890
oligodendroglioma 15 | 2,850
pituitary cancer 15 | 1,972
Pick disease 14 | 1,894
interstitial cystitis 14 | 2,312
lung adenocarcinoma 14 | 2,716
lung carcinoma 14 | 2,843
Kidney cancer 13 | 2,613
primitive neuroectodermal tumor 12 | 3,035
subependymal giant cell astrocytoma 12 | 2,287
Autosomal recessive predisposition 11 | 1,442
invasive ductal carcinoma 11 | 2,951
tuberculosis 11 | 2,010
colon cancer 10 | 1,478
intraductal papillary-mucinous adenoma (IPMA) 10 | 2,955
ulcerative colitis 10 | 1,819
Amyotrophic lateral sclerosis 9 | 451
Alzheimer's disease 8 | 658
Depressive disorder 8 | 409
Intellectual disability 8 | 1,016
Liver Cirrhosis, Experimental 8 | 769
Neurodegenerative disease 8 | 414
Neuropathy 8 | 261
acute quadriplegic myopathy 8 | 1,158
group 4 medulloblastoma 8 | 1,855
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,291
Down syndrome 7 | 499
Dull intelligence 7 | 645
Liver cancer 7 | 604
Low intelligence 7 | 645
Mental Retardation 7 | 645
Mental deficiency 7 | 645
Parkinson's disease 7 | 392
Poor school performance 7 | 645
breast carcinoma 7 | 1,638
cutaneous lupus erythematosus 7 | 1,057
ductal carcinoma in situ 7 | 1,745
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,989
pancreatic cancer 7 | 2,398
spina bifida 7 | 1,074
Bipolar Disorder 6 | 666
Congenital myasthenic syndrome 6 | 25
Dementia 6 | 175
Epilepsy 6 | 792
Heart failure 6 | 162
Mental Depression 6 | 333
diabetes mellitus 6 | 1,728
juvenile dermatomyositis 6 | 1,187
nasopharyngeal carcinoma 6 | 1,058
primary pancreatic ductal adenocarcinoma 6 | 1,109
Acquired scoliosis 5 | 281
Blepharoptosis 5 | 231
Cardiomyopathy 5 | 116
Cognitive delay 5 | 608
Curvature of spine 5 | 282
Duchenne muscular dystrophy 5 | 601
Fetal Growth Retardation 5 | 189
Global developmental delay 5 | 608
Hypoplastic mandible condyle 5 | 275
Kidney disease 5 | 430
Mandibular hypoplasia 5 | 275
Mental and motor retardation 5 | 608
Micrognathism 5 | 275
Muscle hypotonia 5 | 571
Nerve Degeneration 5 | 121
Orbital separation excessive 5 | 244
Seizures 5 | 596
Toxic encephalopathy 5 | 141
active Crohn's disease 5 | 922
esophageal adenocarcinoma 5 | 737
primary Sjogren syndrome 5 | 735
progressive supranuclear palsy 5 | 676
Cardiomyopathy, Dilated 4 | 83
Cerebrovascular disease 4 | 238
Concave bridge of nose 4 | 195
Depressed nasal bridge 4 | 195
Depressed nasal root/bridge 4 | 195
Mood Disorders 4 | 184
Vascular disease 4 | 319
acute myeloid leukemia 4 | 783
cystic fibrosis 4 | 1,696
dermatomyositis 4 | 966
pediatric high grade glioma 4 | 1,064

Tissue

Digestive Tract 56 | 17,369
Endocrine System 56 | 18,159
Liver and Pancreas 56 | 16,750
Female tissues 55 | 17,400
Male tissues 55 | 17,142
Skin and soft tissues 55 | 17,230
Nervous System 54 | 16,725
Respiratory system 54 | 16,393
Blood and immune system 53 | 16,909
Cardiovascular System 53 | 15,192
Urinary Tract 53 | 16,678

Target Family

Non-IDG 37 | 12,091
Enzyme 7 | 4,145
Kinase 5 | 634
Ion Channel 3 | 344
Transporter 2 | 473
Epigenetic 1 | 242
GPCR 1 | 408

GO Component

neuromuscular junction 56 | 56
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
43 kDa receptor-associated protein of the synapse RAPSN Tbio Non-IDG -2.09902 132.1 134
Desmin DES Tbio Non-IDG -1.56068 36.6 991
Alpha-1-syntrophin SNTA1 Tbio Non-IDG -1.49227 31.4 254
Acetylcholine receptor subunit alpha CHRNA1 Tclin Ion Channel -1.66400 41.7 307
Ephrin-A2 EFNA2 Tbio Non-IDG -1.78296 60.7 253
E3 ubiquitin-protein ligase PDZRN3 PDZRN3 Tbio Enzyme -1.20019 15.7 71
TBC1 domain family member 24 TBC1D24 Tbio Non-IDG -2.24696 145.0 34
F-BAR and double SH3 domains protein 2 FCHSD2 Tbio Non-IDG -1.56117 35.3 75
Neurabin-1 PPP1R9A Tbio Non-IDG -1.00329 12.4 117
F-BAR and double SH3 domains protein 1 FCHSD1 Tdark Non-IDG -0.23145 1.99 81