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Development Level

Tbio 16 | 11,445

IMPC Phenotype

abnormal behavioral response t... 1 | 66
abnormal bone structure 1 | 187
abnormal motor learning 1 | 3
abnormal sleep behavior 1 | 70
abnormal vocalization 1 | 21
absent startle reflex 1 | 24
convulsive seizures 1 | 13
decreased anxiety-related resp... 1 | 12
decreased body length 1 | 101
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased exploration in new e... 1 | 11
decreased grip strength 1 | 116
decreased lean body mass 1 | 135
decreased leukocyte cell numbe... 1 | 73
decreased prepulse inhibition 1 | 82
decreased startle reflex 1 | 75
decreased urine creatinine lev... 1 | 3
increased body length 1 | 32
increased erythrocyte cell num... 1 | 39
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased or absent threshold ... 1 | 101
increased total body fat amoun... 1 | 134

Disease

Carcinoma 16 | 11,493
Kidney cancer 11 | 2,613
psoriasis 11 | 6,694
Melanoma 9 | 711
Skin cancer 9 | 469
acute quadriplegic myopathy 9 | 1,158
Breast cancer 7 | 3,578
Distal arthrogryposis 7 | 42
lung adenocarcinoma 5 | 2,716
Autosomal recessive predisposition 4 | 1,442
Duchenne muscular dystrophy 4 | 601
Hypertrophic Cardiomyopathy 4 | 117
Liver cancer 4 | 604
Myopathy 4 | 185
Ophthalmoplegia 4 | 106
atypical teratoid / rhabdoid tumor 4 | 5,112
glioblastoma 4 | 5,792
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
medulloblastoma, large-cell 4 | 6,241
Arthrogryposis 3 | 54
Becker muscular dystrophy 3 | 191
Blepharoptosis 3 | 231
Byzanthine arch palate 3 | 194
Dilated cardiomyopathy 3 | 56
Distal arthrogryposis syndrome 3 | 8
Endometrial cancer 3 | 311
MYH-9 related disease 3 | 12
breast carcinoma 3 | 1,638
colon cancer 3 | 1,478
group 4 medulloblastoma 3 | 1,855
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
juvenile dermatomyositis 3 | 1,187
limb girdle muscular dystrophy 2A 3 | 213
malignant mesothelioma 3 | 3,232
primitive neuroectodermal tumor 3 | 3,035
Abdomen distended 2 | 43
Abnormality of metabolism/homeostasis 2 | 134
Acquired scoliosis 2 | 281
Adducted thumb 2 | 22
Amyotrophic lateral sclerosis 2 | 451
Ankyloglossia 2 | 17
Astrocytoma, Pilocytic 2 | 3,081
Asymmetric Septal Hypertrophy 2 | 7
Atrial Septal Defects 2 | 85
Cardiac Arrhythmia 2 | 103
Cardiac conduction abnormalities 2 | 78
Cardiomyopathy 2 | 116
Cardiomyopathy, Dilated 2 | 83
Cardiomyopathy, Familial Hypertrophic, 1 2 | 6
Cardiomyopathy, Familial Hypertrophic, 1 (disorder) 2 | 7
Cardiomyopathy, Hypertrophic, Familial 2 | 9
Chest Pain 2 | 38
Clubfoot 2 | 39
Conduction disorder of the heart 2 | 79
Congenital clubfoot 2 | 109
Congestive heart failure 2 | 113
Curvature of spine 2 | 282
Deglutition Disorders 2 | 132
Dilatation of ureter 2 | 15
EKG abnormalities 2 | 78
Electrocardiogram abnormal 2 | 81
Electrocardiogram change 2 | 78
Failure to gain weight 2 | 365
Familial isolated dilated cardiomyopathy 2 | 41
Flexion contracture of proximal interphalangeal joint 2 | 75
Generalized muscle weakness 2 | 57
Heart failure 2 | 162
Highly variable severity 2 | 157
Joint stiffness 2 | 84
Kidney disease 2 | 430
LEFT VENTRICULAR NONCOMPACTION 10 2 | 40
LEFT VENTRICULAR NONCOMPACTION 8 2 | 40
Left ventricular noncompaction 2 | 26
Metatarsus Varus 2 | 24
Microcolon 2 | 4
Microcolon on contrast enema 2 | 4
Myocardial Infarction 2 | 151
Narrow face 2 | 54
Nausea and vomiting 2 | 97
Neck muscle weakness 2 | 17
Overlapping fingers 2 | 10
Pediatric failure to thrive 2 | 365
Pick disease 2 | 1,894
Polyhydramnios 2 | 108
Proximal muscle weakness 2 | 47
Proximal neurogenic muscle weakness 2 | 47
Subaortic stenosis 2 | 9
Thin face 2 | 54
Toeing-in 2 | 24
Ulnar deviation of the fingers 2 | 21
Uroureter 2 | 15
Variable expressivity 2 | 157
adult high grade glioma 2 | 3,801
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
diabetes mellitus 2 | 1,728
megacystis-microcolon-intestinal hypoperistalsis syndrome 2 | 10
ovarian cancer 2 | 8,520
pediatric high grade glioma 2 | 1,064
posterior fossa group B ependymoma 2 | 416

Tissue

Endocrine System 16 | 18,159
Skin and soft tissues 16 | 17,230
Digestive Tract 15 | 17,369
Male tissues 14 | 17,142
Blood and immune system 13 | 16,909
Cardiovascular System 13 | 15,192
Female tissues 12 | 17,400
Liver and Pancreas 12 | 16,750
Nervous System 12 | 16,725
Urinary Tract 11 | 16,678
Respiratory system 10 | 16,393

Target Family

Non-IDG 16 | 12,091

GO Component

myosin filament 16 | 16
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Myomesin-2 MYOM2 Tbio Non-IDG -3.36742 2270.3 100
Myosin-6 MYH6 Tbio Non-IDG -2.95952 901.3 45
Myosin-7 MYH7 Tbio Non-IDG -2.64013 417.6 176
Myosin-11 MYH11 Tbio Non-IDG -2.63453 415.3 263
Myosin-binding protein H MYBPH Tbio Non-IDG -2.52998 324.4 146
Myosin-2 MYH2 Tbio Non-IDG -2.14128 114.9 63
Actin, gamma-enteric smooth muscle ACTG2 Tbio Non-IDG -1.98240 92.4 212
Myosin-binding protein C, fast-type MYBPC2 Tbio Non-IDG -1.90462 81.5 107
Myosin-1 MYH1 Tbio Non-IDG -1.94251 72.6 122
Myosin-4 MYH4 Tbio Non-IDG -1.81214 51.8 52