Development Level

Tbio 28 | 11,651
Tdark 5 | 6,593

IMPC Phenotype

preweaning lethality, complete... 5 | 979
abnormal embryo size 3 | 220
abnormal placenta size 2 | 20
embryonic growth retardation 2 | 106
hemorrhage 2 | 23
abnormal behavior 1 | 298
abnormal behavioral response t... 1 | 66
abnormal coat-hair pigmentatio... 1 | 64
abnormal cornea morphology 1 | 31
abnormal craniofacial morpholo... 1 | 33
abnormal digit morphology 1 | 10
abnormal eye morphology 1 | 68
abnormal forebrain morphology 1 | 10
abnormal limb bud morphology 1 | 17
abnormal neural tube closure 1 | 46
abnormal pericardium morpholog... 1 | 26
abnormal retina morphology 1 | 71
abnormal skin coloration 1 | 25
abnormal tail morphology 1 | 25
cardiovascular system phenotyp... 1 | 36
convulsive seizures 1 | 13
corneal opacity 1 | 32
cyanosis 1 | 7
decreased caudal vertebrae num... 1 | 53
decreased circulating creatini... 1 | 39
decreased circulating iron lev... 1 | 32
decreased lean body mass 1 | 135
decreased leukocyte cell numbe... 1 | 73
decreased mean corpuscular vol... 1 | 79
edema 1 | 59
embryonic lethality prior to t... 1 | 278
fused cornea and lens 1 | 5
fused phalanges 1 | 1
hyperactivity 1 | 148
impaired pupillary reflex 1 | 26
improved glucose tolerance 1 | 79
increased circulating iron lev... 1 | 30
increased circulating sodium l... 1 | 71
increased heart rate variabili... 1 | 7
increased heart weight 1 | 62
increased or absent threshold ... 1 | 101
increased urine magnesium leve... 1 | 2
pale liver 1 | 6
pale yolk sac 1 | 25
pallor 1 | 34
persistence of hyaloid vascula... 1 | 33
prenatal lethality prior to he... 1 | 87
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 23 | 11,493
Kidney cancer 15 | 2,613
psoriasis 14 | 6,694
osteosarcoma 12 | 7,950
ovarian cancer 12 | 8,520
non-small cell lung cancer 9 | 2,890
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,989
atypical teratoid / rhabdoid tumor 7 | 5,112
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,291
lung carcinoma 7 | 2,843
malignant mesothelioma 7 | 3,232
Hypertrophic Cardiomyopathy 6 | 117
Liver cancer 6 | 604
glioblastoma 6 | 5,792
lung adenocarcinoma 6 | 2,716
lung cancer 6 | 4,740
medulloblastoma, large-cell 6 | 6,241
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,962
pituitary cancer 6 | 1,972
ulcerative colitis 6 | 1,819
Autosomal recessive predisposition 5 | 1,442
Breast cancer 5 | 3,578
acute quadriplegic myopathy 5 | 1,158
pancreatic cancer 5 | 2,398
primitive neuroectodermal tumor 5 | 3,035
Cardiomyopathy, Hypertrophic 4 | 24
Schizophrenia 4 | 1,160
cystic fibrosis 4 | 1,696
ductal carcinoma in situ 4 | 1,745
ependymoma 4 | 4,679
group 3 medulloblastoma 4 | 4,104
spina bifida 4 | 1,074
Astrocytoma, Pilocytic 3 | 3,081
Cardiomyopathy 3 | 116
Cardiomyopathy, Hypertrophic, Familial 3 | 9
Dilated cardiomyopathy 3 | 56
Melanoma 3 | 711
Myopathy 3 | 185
Nonsyndromic deafness 3 | 142
Skin cancer 3 | 469
adult high grade glioma 3 | 3,801
interstitial cystitis 3 | 2,312
pediatric high grade glioma 3 | 1,064
Abnormality of metabolism/homeostasis 2 | 134
Acquired scoliosis 2 | 281
Asymmetric Septal Hypertrophy 2 | 7
Atrial Septal Defects 2 | 85
Cardiac Arrhythmia 2 | 103
Cardiac conduction abnormalities 2 | 78
Cardiomyopathy, Dilated 2 | 83
Cardiomyopathy, Familial Hypertrophic, 1 2 | 6
Cardiomyopathy, Familial Hypertrophic, 1 (disorder) 2 | 7
Cardiovascular system disease 2 | 246
Conduction disorder of the heart 2 | 79
Congenital myopathy with fiber type disproportion 2 | 9
Congestive heart failure 2 | 113
Curvature of spine 2 | 282
Distal arthrogryposis 2 | 42
EKG abnormalities 2 | 78
Electrocardiogram abnormal 2 | 81
Electrocardiogram change 2 | 78
Endometrial cancer 2 | 311
Essential Hypertension 2 | 94
Familial isolated dilated cardiomyopathy 2 | 41
Focal glomerulosclerosis 2 | 37
Glomerulosclerosis, Focal Segmental 2 | 28
Heart failure 2 | 162
Hodgkin's lymphoma, nodular sclerosis 2 | 22
LEFT VENTRICULAR NONCOMPACTION 10 2 | 40
LEFT VENTRICULAR NONCOMPACTION 8 2 | 40
Left ventricular noncompaction 2 | 26
Myocardial Infarction 2 | 151
Sensorineural hearing loss 2 | 106
Sick sinus syndrome 2 | 15
Subaortic stenosis 2 | 9
Sudden death 2 | 16
Weight Gain 2 | 100
astrocytic glioma 2 | 2,597
diabetes mellitus 2 | 1,728
facioscapulohumeral dystrophy 2 | 288
gastric carcinoma 2 | 807
group 4 medulloblastoma 2 | 1,855
invasive ductal carcinoma 2 | 2,951
medulloblastoma 2 | 720
nasopharyngeal carcinoma 2 | 1,058
oligodendroglioma 2 | 2,850
subependymal giant cell astrocytoma 2 | 2,287
Cardiovascular Abnormalities 1 | 31
Chronic Kidney Diseases 1 | 13
Congenital Fiber Type Disproportion 1 | 7
Ostium secundum atrial septal defect 1 | 9
Respiratory insufficiency due to muscle weakness 1 | 37
Scapular weakness 1 | 23
Scapuloperoneal myopathy 1 | 6
Scapuloperoneal weakness 1 | 3
Tachycardia, Ventricular 1 | 22
Weak cry 1 | 17
Winged scapula 1 | 23
X-Linked Emery-Dreifuss Muscular Dystrophy 1 | 3

Tissue

Endocrine System 31 | 18,159
Female tissues 31 | 17,400
Skin and soft tissues 31 | 17,230
Digestive Tract 30 | 17,369
Male tissues 30 | 17,142
Blood and immune system 29 | 16,909
Liver and Pancreas 29 | 16,750
Nervous System 28 | 16,725
Urinary Tract 28 | 16,678
Cardiovascular System 27 | 15,192
Respiratory system 26 | 16,393

Target Family

Non-IDG 31 | 12,091
Kinase 2 | 634

GO Component

myosin complex 33 | 33
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Unconventional myosin-VIIb MYO7B Tbio Non-IDG -0.65885 5.07 14
Unconventional myosin-Vb MYO5B Tbio Non-IDG -1.96052 93.4 42
Unconventional myosin-Id MYO1D Tbio Non-IDG -1.39704 23.1 63
Cingulin-like protein 1 CGNL1 Tbio Non-IDG -0.84049 8.54 64
Unconventional myosin-XV MYO15A Tbio Non-IDG -1.64094 42.8 15
Myosin light polypeptide 6 MYL6 Tbio Non-IDG -1.86799 68.9 257
Myosin regulatory light chain 2, ventricular/cardiac muscle isoform MYL2 Tbio Non-IDG -2.23022 155.8 222
Myosin-IIIa MYO3A Tbio Kinase -1.25280 20.1 130
Coiled-coil domain-containing protein 102A CCDC102A Tdark Non-IDG 0.95 0.10 86
Myosin regulatory light chain 12A MYL12A Tbio Non-IDG -1.53157 32.9 93