Development Level

Tbio 100 | 10,625
Tchem 27 | 1,890
Tclin 16 | 602
Tdark 1 | 7,003

IMPC Term

preweaning lethality, complete... 12 | 633
embryonic lethality prior to o... 6 | 148
embryonic lethality prior to t... 6 | 187
hyperactivity 6 | 108
abnormal behavior 5 | 226
preweaning lethality, incomple... 4 | 260
decreased body weight 3 | 174
decreased caudal vertebrae num... 3 | 49
decreased fasted circulating g... 3 | 49
decreased lean body mass 3 | 195
increased circulating alkaline... 3 | 119
increased circulating choleste... 3 | 53
decreased body length 2 | 108
decreased bone mineral content 2 | 157
decreased circulating HDL chol... 2 | 77
decreased circulating insulin ... 2 | 75
decreased grip strength 2 | 123
decreased mean corpuscular vol... 2 | 50
decreased startle reflex 2 | 48
decreased total body fat amoun... 2 | 186
hypoactivity 2 | 89
increased blood urea nitrogen ... 2 | 44
increased heart weight 2 | 37
increased lean body mass 2 | 107
abnormal allantois morphology 1 | 3
abnormal behavioral response t... 1 | 52
abnormal bone structure 1 | 131
abnormal coping response 1 | 12
abnormal embryo size 1 | 112
abnormal gait 1 | 51
abnormal heart morphology 1 | 51
abnormal lens morphology 1 | 73
abnormal limb bud morphology 1 | 15
abnormal locomotor activation 1 | 26
abnormal lung morphology 1 | 15
abnormal neural tube closure 1 | 37
abnormal neural tube morpholog... 1 | 8
abnormal retinal pigmentation 1 | 61
abnormal skin morphology 1 | 23
abnormal sleep behavior 1 | 63
abnormal snout morphology 1 | 18
abnormal spine curvature 1 | 7
abnormal tail bud morphology 1 | 6
abnormal tail movements 1 | 12
convulsive seizures 1 | 11
decreased IgM level 1 | 1
decreased NK T cell number 1 | 28
decreased anxiety-related resp... 1 | 12
decreased bone mineral density 1 | 126
decreased circulating bilirubi... 1 | 14
decreased circulating chloride... 1 | 32
decreased circulating glycerol... 1 | 19
decreased circulating iron lev... 1 | 25
decreased circulating triglyce... 1 | 83
decreased effector memory CD8-... 1 | 24
decreased erythrocyte cell num... 1 | 43
decreased hemoglobin content 1 | 53
decreased lactate dehydrogenas... 1 | 14
decreased mean corpuscular hem... 1 | 34
decreased respiratory quotient 1 | 12
enlarged heart 1 | 111
female infertility 1 | 34
impaired glucose tolerance 1 | 52
impaired righting response 1 | 19
improved glucose tolerance 1 | 56
increased B-1a cell number 1 | 2
increased bone mineral content 1 | 92
increased bone mineral density 1 | 52
increased circulating HDL chol... 1 | 63
increased circulating calcium ... 1 | 32
increased circulating chloride... 1 | 43
increased circulating creatini... 1 | 29
increased circulating free fat... 1 | 17
increased circulating phosphat... 1 | 24
increased circulating sodium l... 1 | 71
increased circulating triglyce... 1 | 24
increased erythrocyte cell num... 1 | 26
increased grip strength 1 | 83
increased hematocrit 1 | 36
increased hemoglobin content 1 | 45
increased mean corpuscular hem... 1 | 93
increased or absent threshold ... 1 | 128
increased total body fat amoun... 1 | 57
male infertility 1 | 62
short tibia 1 | 82
small adrenal glands 1 | 15
small lymph nodes 1 | 1
straub tail 1 | 26
tremors 1 | 34

Disease

ovarian cancer 99 | 8,484
glioblastoma 76 | 5,572
medulloblastoma, large-cell 71 | 6,234
psoriasis 56 | 6,685
lung cancer 53 | 4,466
oligodendroglioma 52 | 2,849
osteosarcoma 52 | 7,933
atypical teratoid / rhabdoid tumor 49 | 4,369
ependymoma 45 | 2,514
pilocytic astrocytoma 45 | 3,086
Cancer 43 | 2,346
Multiple myeloma 42 | 1,327
Pick disease 42 | 1,893
pediatric high grade glioma 41 | 2,712
lung adenocarcinoma 39 | 2,713
primitive neuroectodermal tumor 39 | 3,031
astrocytic glioma 37 | 2,241
intraductal papillary-mucinous neoplasm (IPMN) 37 | 3,289
subependymal giant cell astrocytoma 37 | 2,287
Breast cancer 36 | 3,094
intraductal papillary-mucinous carcinoma (IPMC) 34 | 2,988
lung carcinoma 32 | 2,844
pancreatic cancer 32 | 2,300
astrocytoma 31 | 1,493
intraductal papillary-mucinous adenoma (IPMA) 31 | 2,956
invasive ductal carcinoma 31 | 2,950
non-small cell lung cancer 31 | 2,798
colon cancer 30 | 1,475
malignant mesothelioma 30 | 3,162
adult high grade glioma 26 | 2,148
pancreatic ductal adenocarcinoma liver metastasis 26 | 1,795
atypical teratoid/rhabdoid tumor 25 | 1,095
Waldenstrons macroglobulinemia 23 | 765
medulloblastoma 23 | 1,524
ulcerative colitis 22 | 2,087
breast carcinoma 21 | 1,614
cystic fibrosis 21 | 1,665
ductal carcinoma in situ 21 | 1,745
sonic hedgehog group medulloblastoma 21 | 1,482
Alzheimer's disease 20 | 644
diabetes mellitus 20 | 1,663
group 4 medulloblastoma 20 | 1,875
interstitial cystitis 19 | 2,299
pituitary cancer 19 | 1,972
Down syndrome 17 | 548
Epilepsy 17 | 346
Parkinson's disease 17 | 364
primary pancreatic ductal adenocarcinoma 17 | 1,271
acute quadriplegic myopathy 16 | 1,157
group 3 medulloblastoma 16 | 2,254
Duchenne muscular dystrophy 15 | 602
tuberculosis 15 | 1,557
Neuropathy 14 | 210
adrenocortical carcinoma 14 | 1,427
Neurodegenerative disease 13 | 383
Prostatic Neoplasms 13 | 471
dermatomyositis 13 | 933
posterior fossa group A ependymoma 13 | 1,511
posterior fossa group B ependymoma 13 | 1,530
Atopic dermatitis 12 | 944
Degenerative polyarthritis 12 | 93
Rheumatoid Arthritis 12 | 1,160
juvenile dermatomyositis 12 | 1,189
Mammary Neoplasms 11 | 410
hereditary spastic paraplegia 11 | 313
Animal Mammary Neoplasms 10 | 136
Intellectual disability 10 | 573
Liver carcinoma 10 | 217
Mammary Neoplasms, Experimental 10 | 150
Myocardial Ischemia 10 | 169
Osteoporosis 10 | 257
Schizophrenia 10 | 501
Stomach Neoplasms 10 | 282
Amyotrophic Lateral Sclerosis 9 | 431
Carcinoma 9 | 2,147
Multiple Sclerosis 9 | 498
esophageal adenocarcinoma 9 | 737
progressive supranuclear palsy 9 | 674
Leigh disease 8 | 81
Obesity 8 | 616
Peripheral Neuropathy 8 | 303
active Crohn's disease 8 | 918
nasopharyngeal carcinoma 8 | 1,056
non-small cell lung carcinoma 8 | 413
Adenocarcinoma 7 | 115
Charcot-Marie-Tooth disease 7 | 74
HIV Infections 7 | 100
IGA Glomerulonephritis 7 | 454
acute myeloid leukemia 7 | 780
cutaneous lupus erythematosus 7 | 1,056
fibroadenoma 7 | 557
hepatocellular carcinoma 7 | 532
pancreatic carcinoma 7 | 567
Becker muscular dystrophy 6 | 187
Endometriosis 6 | 535
Vascular disease 6 | 281
aldosterone-producing adenoma 6 | 664
autosomal dominant Emery-Dreifuss muscular dystrophy 6 | 499
chronic rhinosinusitis 6 | 512
gastric carcinoma 6 | 832

Tissue

Blood and immune system 144 | 17,995
Cardiovascular System 144 | 17,958
Digestive Tract 144 | 18,473
Endocrine System 144 | 18,512
Female tissues 144 | 18,647
Liver and Pancreas 144 | 18,136
Male tissues 144 | 17,969
Nervous System 144 | 18,561
Respiratory system 144 | 17,484
Urinary Tract 144 | 18,444
Skin and soft tissues 143 | 18,115

Target Family

Non-IDG 81 | 11,971
Enzyme 48 | 4,146
Transporter 8 | 473
Kinase 4 | 634
Ion Channel 2 | 341
Epigenetic 1 | 242

GO Component

myelin sheath 144 | 144
nucleus 5,107 | 5,107
cytoplasm 4,985 | 4,985
plasma membrane 4,118 | 4,118
integral component of membrane 3,679 | 3,679
cytosol 3,265 | 3,265
extracellular exosome 2,758 | 2,758
nucleoplasm 2,717 | 2,717
membrane 1,906 | 1,906
extracellular region 1,493 | 1,493
integral component of plasma m... 1,406 | 1,406
extracellular space 1,304 | 1,304
mitochondrion 1,231 | 1,231
Golgi apparatus 864 | 864
endoplasmic reticulum 859 | 859
endoplasmic reticulum membrane 848 | 848
nucleolus 815 | 815
Golgi membrane 659 | 659
perinuclear region of cytoplas... 611 | 611
cell surface 594 | 594
intracellular 548 | 548
intracellular membrane-bounded... 537 | 537
cell junction 451 | 451
mitochondrial inner membrane 425 | 425
centrosome 409 | 409
focal adhesion 383 | 383
protein complex 355 | 355
cytoskeleton 343 | 343
dendrite 329 | 329
mitochondrial matrix 322 | 322
cell-cell adherens junction 307 | 307
neuronal cell body 303 | 303
microtubule 294 | 294
lysosomal membrane 278 | 278
apical plasma membrane 277 | 277
proteinaceous extracellular ma... 244 | 244
neuron projection 229 | 229
nuclear membrane 218 | 218
early endosome 217 | 217
axon 214 | 214
lysosome 210 | 210
endosome 208 | 208
actin cytoskeleton 205 | 205
external side of plasma membra... 205 | 205
postsynaptic membrane 204 | 204
extracellular matrix 198 | 198
nuclear speck 197 | 197
membrane raft 196 | 196
endoplasmic reticulum lumen 192 | 192
transcription factor complex 184 | 184
endosome membrane 182 | 182
early endosome membrane 180 | 180
basolateral plasma membrane 174 | 174
nuclear chromatin 169 | 169
synapse 166 | 166
cell-cell junction 161 | 161
nuclear envelope 156 | 156
lamellipodium 153 | 153
mitochondrial outer membrane 148 | 148
blood microparticle 147 | 147
postsynaptic density 144 | 144
cytoplasmic vesicle 143 | 143
microtubule organizing center 137 | 137
cytoplasmic, membrane-bounded ... 132 | 132
ER to Golgi transport vesicle ... 131 | 131
microtubule cytoskeleton 127 | 127
receptor complex 127 | 127
phagocytic vesicle membrane 126 | 126
cytoplasmic vesicle membrane 125 | 125
midbody 125 | 125
trans-Golgi network 124 | 124
cell cortex 119 | 119
cilium 118 | 118
late endosome 116 | 116
spindle 116 | 116
intracellular ribonucleoprotei... 114 | 114
vesicle 112 | 112
Z disc 110 | 110
bicellular tight junction 110 | 110
anchored component of membrane 109 | 109
growth cone 109 | 109
integral component of lumenal ... 108 | 108
late endosome membrane 107 | 107
endomembrane system 106 | 106
centriole 105 | 105
recycling endosome 104 | 104
spindle pole 104 | 104
perikaryon 103 | 103
integral component of endoplas... 101 | 101
intermediate filament 101 | 101
melanosome 101 | 101
chromosome 100 | 100
dendritic spine 99 | 99
ubiquitin ligase complex 99 | 99
peroxisome 98 | 98
nuclear matrix 97 | 97
PML body 94 | 94
Golgi lumen 93 | 93
keratin filament 93 | 93
trans-Golgi network membrane 92 | 92

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
ADP/ATP translocase 1 SLC25A4 Tbio Transporter -2.05462 110.8 89
Neurofilament heavy polypeptide NEFH Tbio Non-IDG -2.73883 563.3 681
Malate dehydrogenase, mitochondrial MDH2 Tchem Enzyme -2.21960 180.2 229
Malate dehydrogenase, cytoplasmic MDH1 Tbio Enzyme -2.61325 409.6 244
V-type proton ATPase catalytic subunit A ATP6V1A Tbio Enzyme -1.80191 64.7 120
Pyruvate kinase PKM PKM Tchem Kinase -3.09101 1313.5 672
Alpha-centractin ACTR1A Tbio Non-IDG -0.72323 6.08 149
ATP synthase F(0) complex subunit B1, mitochondrial ATP5F1 Tbio Enzyme -0.80065 5.85 92
Ras-related protein Ral-A RALA Tbio Enzyme -2.17133 159.2 185
Sodium/potassium-transporting ATPase subunit alpha-2 ATP1A2 Tclin Transporter -2.04732 117.9 108