Development Level

Tbio 102 | 11,445
Tchem 23 | 1,598
Tclin 18 | 613
Tdark 1 | 6,588

IMPC Phenotype

preweaning lethality, complete... 14 | 979
embryonic lethality prior to t... 7 | 278
preweaning lethality, incomple... 7 | 499
embryonic lethality prior to o... 6 | 239
abnormal behavior 5 | 298
hyperactivity 5 | 148
increased circulating alkaline... 5 | 122
decreased fasted circulating g... 4 | 65
decreased grip strength 3 | 116
decreased total body fat amoun... 3 | 207
increased lean body mass 3 | 172
abnormal gait 2 | 69
abnormal sleep behavior 2 | 70
convulsive seizures 2 | 13
decreased circulating bilirubi... 2 | 19
decreased circulating insulin ... 2 | 76
decreased circulating iron lev... 2 | 32
decreased circulating serum al... 2 | 82
decreased circulating triglyce... 2 | 79
decreased lean body mass 2 | 135
decreased startle reflex 2 | 75
decreased vertical activity 2 | 208
enlarged heart 2 | 210
hypoactivity 2 | 132
increased blood urea nitrogen ... 2 | 48
increased circulating calcium ... 2 | 34
increased circulating choleste... 2 | 66
increased circulating triglyce... 2 | 42
increased heart weight 2 | 62
pallor 2 | 34
prenatal lethality prior to he... 2 | 87
tremors 2 | 39
abnormal allantois morphology 1 | 8
abnormal behavioral response t... 1 | 66
abnormal bone structure 1 | 187
abnormal cranium morphology 1 | 36
abnormal embryo size 1 | 220
abnormal embryo turning 1 | 31
abnormal heart looping 1 | 5
abnormal heart morphology 1 | 162
abnormal lens morphology 1 | 81
abnormal limb bud morphology 1 | 17
abnormal lung morphology 1 | 26
abnormal neural tube closure 1 | 46
abnormal neural tube morpholog... 1 | 12
abnormal pharyngeal arch morph... 1 | 8
abnormal retina morphology 1 | 71
abnormal skin morphology 1 | 50
abnormal snout morphology 1 | 23
abnormal spine curvature 1 | 9
abnormal tail bud morphology 1 | 8
abnormal tail movements 1 | 12
absent pinna reflex 1 | 23
cataract 1 | 92
decreased IgM level 1 | 1
decreased anxiety-related resp... 1 | 12
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 53
decreased circulating HDL chol... 1 | 68
decreased circulating chloride... 1 | 30
decreased circulating choleste... 1 | 93
decreased circulating glucose ... 1 | 126
decreased coping response 1 | 8
decreased erythrocyte cell num... 1 | 62
decreased hemoglobin content 1 | 68
decreased lactate dehydrogenas... 1 | 16
decreased leukocyte cell numbe... 1 | 73
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular vol... 1 | 79
decreased respiratory quotient 1 | 16
decreased spleen weight 1 | 10
embryonic growth retardation 1 | 106
enlarged kidney 1 | 14
enlarged spleen 1 | 41
female infertility 1 | 60
impaired glucose tolerance 1 | 75
impaired righting response 1 | 26
improved glucose tolerance 1 | 79
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating amylase ... 1 | 25
increased circulating chloride... 1 | 41
increased circulating creatini... 1 | 38
increased circulating phosphat... 1 | 26
increased circulating sodium l... 1 | 71
increased erythrocyte cell num... 1 | 39
increased grip strength 1 | 41
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased spleen weight 1 | 10
increased total body fat amoun... 1 | 134
male infertility 1 | 123
pale yolk sac 1 | 25
prolonged PR interval 1 | 15
short tibia 1 | 97
small adrenal glands 1 | 16
small testis 1 | 58

Disease

ovarian cancer 99 | 8,520
Carcinoma 93 | 11,493
glioblastoma 80 | 5,792
medulloblastoma, large-cell 71 | 6,241
atypical teratoid / rhabdoid tumor 70 | 5,112
ependymoma 68 | 4,679
psoriasis 56 | 6,694
adult high grade glioma 55 | 3,801
lung cancer 54 | 4,740
group 3 medulloblastoma 53 | 4,104
oligodendroglioma 52 | 2,850
osteosarcoma 51 | 7,950
astrocytic glioma 50 | 2,597
Astrocytoma, Pilocytic 48 | 3,081
Cancer 47 | 2,499
Pick disease 43 | 1,894
Breast cancer 42 | 3,578
Multiple myeloma 39 | 1,332
primitive neuroectodermal tumor 39 | 3,035
intraductal papillary-mucinous neoplasm (IPMN) 37 | 3,291
intraductal papillary-mucinous carcinoma (IPMC) 36 | 2,989
subependymal giant cell astrocytoma 36 | 2,287
Autosomal recessive predisposition 35 | 1,442
lung adenocarcinoma 35 | 2,716
Epilepsy 34 | 792
Schizophrenia 34 | 1,160
intraductal papillary-mucinous adenoma (IPMA) 32 | 2,955
pancreatic cancer 32 | 2,398
invasive ductal carcinoma 31 | 2,951
lung carcinoma 31 | 2,843
colon cancer 30 | 1,478
malignant mesothelioma 30 | 3,232
non-small cell lung cancer 29 | 2,890
pancreatic ductal adenocarcinoma liver metastasis 25 | 1,962
Muscle hypotonia 22 | 571
Seizures 22 | 596
cystic fibrosis 22 | 1,696
Cognitive delay 21 | 608
Global developmental delay 21 | 608
Intellectual disability 21 | 1,016
Mental and motor retardation 21 | 608
breast carcinoma 21 | 1,638
diabetes mellitus 21 | 1,728
Neuropathy 20 | 261
Waldenstrons macroglobulinemia 20 | 765
astrocytoma 20 | 1,146
ductal carcinoma in situ 20 | 1,745
Alzheimer's disease 19 | 658
Cerebellar Ataxia 19 | 304
pituitary cancer 19 | 1,972
ulcerative colitis 19 | 1,819
Bipolar Disorder 18 | 666
Down syndrome 18 | 499
group 4 medulloblastoma 18 | 1,855
interstitial cystitis 18 | 2,312
Duchenne muscular dystrophy 17 | 601
Parkinson's disease 17 | 392
acute quadriplegic myopathy 17 | 1,158
tuberculosis 17 | 2,010
Failure to gain weight 15 | 365
Nystagmus 15 | 317
Pediatric failure to thrive 15 | 365
adrenocortical carcinoma 15 | 1,428
Depressive disorder 14 | 409
Dull intelligence 14 | 645
Infantile onset 14 | 238
Kidney cancer 14 | 2,613
Low intelligence 14 | 645
Mental Retardation 14 | 645
Mental deficiency 14 | 645
Poor school performance 14 | 645
primary pancreatic ductal adenocarcinoma 14 | 1,109
Blepharoptosis 13 | 231
Neurodegenerative disease 13 | 414
Rheumatoid arthritis 13 | 1,191
dermatomyositis 13 | 966
pediatric high grade glioma 13 | 1,064
Acidosis, Lactic 12 | 97
Animal Mammary Neoplasms 12 | 136
Atopic dermatitis 12 | 952
Dystonia 12 | 164
Hyperreflexia 12 | 209
Mammary Neoplasms, Animal 12 | 136
Mammary Neoplasms, Experimental 12 | 154
Multiple Sclerosis 12 | 540
Muscle Spasticity 12 | 195
Osteoarthritis 12 | 184
Prostatic Neoplasms 12 | 495
Small head 12 | 374
Stomach Neoplasms 12 | 300
juvenile dermatomyositis 12 | 1,187
Carcinoma, Hepatocellular 11 | 228
Degenerative polyarthritis 11 | 115
Lactic acidemia 11 | 95
Liver Cirrhosis, Experimental 11 | 769
Muscle Weakness 11 | 170
Osteoporosis 11 | 363
Respiratory Failure 11 | 104
esophageal adenocarcinoma 11 | 737
hereditary spastic paraplegia 11 | 318

Tissue

Digestive Tract 144 | 17,369
Endocrine System 144 | 18,159
Female tissues 144 | 17,400
Liver and Pancreas 144 | 16,750
Nervous System 144 | 16,725
Skin and soft tissues 144 | 17,230
Blood and immune system 143 | 16,909
Male tissues 143 | 17,142
Respiratory system 143 | 16,393
Urinary Tract 143 | 16,678
Cardiovascular System 139 | 15,192

Target Family

Non-IDG 83 | 12,091
Enzyme 46 | 4,145
Transporter 8 | 473
Kinase 4 | 634
Ion Channel 2 | 344
Epigenetic 1 | 242

GO Component

myelin sheath 144 | 144
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Serine incorporator 5 SERINC5 Tbio Non-IDG -1.50535 34.0 11
Tubulin beta-4A chain TUBB4A Tclin Non-IDG -2.98371 896.1 90
NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial NDUFS1 Tclin Enzyme -1.42734 26.2 214
Phosphate carrier protein, mitochondrial SLC25A3 Tbio Transporter -2.85426 703.4 33
Moesin MSN Tbio Non-IDG -2.61389 361.7 550
Alpha-soluble NSF attachment protein NAPA Tbio Non-IDG -1.91664 86.4 148
T-complex protein 1 subunit alpha TCP1 Tbio Non-IDG -2.26984 173.7 468
Transgelin-3 TAGLN3 Tbio Non-IDG -1.54779 34.2 126
Cytochrome b-c1 complex subunit 1, mitochondrial UQCRC1 Tbio Enzyme -1.46124 30.0 217
Aconitate hydratase, mitochondrial ACO2 Tbio Enzyme -2.21106 157.2 307