Development Level

Tbio 19 | 11,445
Tdark 5 | 6,588

IMPC Phenotype

decreased grip strength 2 | 116
abnormal behavioral response t... 1 | 66
abnormal bone structure 1 | 187
abnormal motor learning 1 | 3
abnormal sleep behavior 1 | 70
abnormal vocalization 1 | 21
absent startle reflex 1 | 24
convulsive seizures 1 | 13
decreased anxiety-related resp... 1 | 12
decreased blood urea nitrogen ... 1 | 51
decreased body length 1 | 101
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating fructosa... 1 | 30
decreased exploration in new e... 1 | 11
decreased lean body mass 1 | 135
decreased leukocyte cell numbe... 1 | 73
decreased prepulse inhibition 1 | 82
decreased startle reflex 1 | 75
decreased urine creatinine lev... 1 | 3
increased body length 1 | 32
increased erythrocyte cell num... 1 | 39
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased or absent threshold ... 1 | 101
increased total body fat amoun... 1 | 134
preweaning lethality, incomple... 1 | 499
thrombocytosis 1 | 27

Disease

Carcinoma 18 | 11,493
Kidney cancer 12 | 2,613
psoriasis 12 | 6,694
acute quadriplegic myopathy 11 | 1,158
Skin cancer 10 | 469
Melanoma 9 | 711
Breast cancer 8 | 3,578
Autosomal recessive predisposition 7 | 1,442
Distal arthrogryposis 7 | 42
Duchenne muscular dystrophy 7 | 601
Becker muscular dystrophy 6 | 191
Hypertrophic Cardiomyopathy 6 | 117
limb girdle muscular dystrophy 2A 6 | 213
lung adenocarcinoma 6 | 2,716
lung cancer 6 | 4,740
medulloblastoma, large-cell 6 | 6,241
Amyotrophic lateral sclerosis 5 | 451
Dilated cardiomyopathy 5 | 56
Liver cancer 5 | 604
Myopathy 5 | 185
atypical teratoid / rhabdoid tumor 5 | 5,112
glioblastoma 5 | 5,792
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
ovarian cancer 5 | 8,520
Blepharoptosis 4 | 231
Cardiomyopathy 4 | 116
Ophthalmoplegia 4 | 106
breast carcinoma 4 | 1,638
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
lung carcinoma 4 | 2,843
malignant mesothelioma 4 | 3,232
osteosarcoma 4 | 7,950
Arthrogryposis 3 | 54
Byzanthine arch palate 3 | 194
Cardiac Arrhythmia 3 | 103
Cardiac conduction abnormalities 3 | 78
Cardiomyopathy, Dilated 3 | 83
Cardiomyopathy, Familial Hypertrophic, 1 3 | 6
Conduction disorder of the heart 3 | 79
Distal arthrogryposis syndrome 3 | 8
EKG abnormalities 3 | 78
Electrocardiogram abnormal 3 | 81
Electrocardiogram change 3 | 78
Endometrial cancer 3 | 311
Familial isolated dilated cardiomyopathy 3 | 41
Generalized muscle weakness 3 | 57
LEFT VENTRICULAR NONCOMPACTION 10 3 | 40
LEFT VENTRICULAR NONCOMPACTION 8 3 | 40
MYH-9 related disease 3 | 12
Primary cutaneous amyloidosis 3 | 29
Proximal muscle weakness 3 | 47
Proximal neurogenic muscle weakness 3 | 47
Short stature 3 | 531
Sudden death 3 | 16
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 510
diabetes mellitus 3 | 1,728
group 4 medulloblastoma 3 | 1,855
juvenile dermatomyositis 3 | 1,187
Abnormality of metabolism/homeostasis 2 | 134
Acquired scoliosis 2 | 281
Adducted thumb 2 | 22
Ankyloglossia 2 | 17
Atrial Septal Defects 2 | 85
Bell Palsy 2 | 58
Chest Pain 2 | 38
Clubfoot 2 | 39
Congenital clubfoot 2 | 109
Congestive heart failure 2 | 113
Creatine phosphokinase serum increased 2 | 110
Curvature of spine 2 | 282
Distal limb muscle weakness due to peripheral neuropathy 2 | 62
Distal muscle weakness 2 | 62
Elevated creatine kinase 2 | 110
Facial Paresis 2 | 59
Facial muscle weakness of muscles innervated by CN VII 2 | 58
Failure to gain weight 2 | 365
Flexion contracture of proximal interphalangeal joint 2 | 75
Heart conduction disease 2 | 83
Heart failure 2 | 162
Highly variable severity 2 | 157
Infantile onset 2 | 238
Kidney disease 2 | 430
Large intestine cancer 2 | 126
Long philtrum 2 | 137
Muscle Weakness 2 | 170
Neck muscle weakness 2 | 17
Overlapping fingers 2 | 10
Pediatric failure to thrive 2 | 365
Prenatal onset 2 | 139
Prominent ear 2 | 56
Protruding ears 2 | 56
Slow progression 2 | 89
Triangular face 2 | 58
Ulnar deviation of the fingers 2 | 21
Variable expressivity 2 | 157
Vertical Talus 2 | 25
hereditary spastic paraplegia 2 | 318
limb-girdle muscular dystrophy 2 | 37
pediatric high grade glioma 2 | 1,064

Tissue

Endocrine System 24 | 18,159
Digestive Tract 23 | 17,369
Skin and soft tissues 23 | 17,230
Male tissues 21 | 17,142
Blood and immune system 20 | 16,909
Nervous System 20 | 16,725
Urinary Tract 20 | 16,678
Cardiovascular System 19 | 15,192
Female tissues 19 | 17,400
Liver and Pancreas 18 | 16,750
Respiratory system 15 | 16,393

Target Family

Non-IDG 23 | 12,091
Kinase 1 | 634

GO Component

muscle myosin complex 24 | 24
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Myosin-13 MYH13 Tbio Non-IDG -1.26079 16.6 12
Myosin-2 MYH2 Tbio Non-IDG -2.14128 114.9 63
Myosin-4 MYH4 Tbio Non-IDG -1.81214 51.8 52
Myosin light chain 1/3, skeletal muscle isoform MYL1 Tbio Non-IDG -2.11698 129.3 109
Immunoglobulin superfamily member 22 IGSF22 Tdark Non-IDG 0.48 0.33 16
Myosin-8 MYH8 Tbio Non-IDG -1.71003 48.7 39
Myosin-6 MYH6 Tbio Non-IDG -2.95952 901.3 45
Titin TTN Tbio Kinase -3.24415 1743.0 123
Myosin light chain 6B MYL6B Tdark Non-IDG -0.48723 2.69 127
Myosin-3 MYH3 Tbio Non-IDG -1.74714 48.2 51