Development Level

Tbio 42 | 11,445
Tchem 7 | 1,598
Tdark 2 | 6,588

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 6 | 979
preweaning lethality, incomple... 4 | 499
embryonic lethality prior to o... 3 | 239
embryonic lethality prior to t... 3 | 278
tremors 2 | 39
abnormal bone structure 1 | 187
abnormal cranium morphology 1 | 36
abnormal embryo size 1 | 220
abnormal retina morphology 1 | 71
abnormal retinal inner nuclear... 1 | 8
abnormal seminal vesicle morph... 1 | 114
abnormal skin morphology 1 | 50
abnormal testis morphology 1 | 43
cardiovascular system phenotyp... 1 | 36
decreased body length 1 | 101
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating serum al... 1 | 82
decreased erythrocyte cell num... 1 | 62
decreased grip strength 1 | 116
decreased lean body mass 1 | 135
decreased prepulse inhibition 1 | 82
decreased spleen weight 1 | 10
decreased startle reflex 1 | 75
decreased threshold for audito... 1 | 26
decreased total body fat amoun... 1 | 207
enlarged kidney 1 | 14
hypoactivity 1 | 132
impaired righting response 1 | 26
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating alkaline... 1 | 122
increased hematocrit 1 | 46
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased mean platelet volume 1 | 45
increased neutrophil cell numb... 1 | 46
increased or absent threshold ... 1 | 101
increased spleen weight 1 | 10
increased total body fat amoun... 1 | 134
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
short tibia 1 | 97
small testis 1 | 58
thrombocytopenia 1 | 56

Disease

ovarian cancer 36 | 8,520
Carcinoma 35 | 11,493
medulloblastoma, large-cell 31 | 6,241
lung cancer 30 | 4,740
group 3 medulloblastoma 25 | 4,104
Breast cancer 24 | 3,578
psoriasis 24 | 6,694
atypical teratoid / rhabdoid tumor 23 | 5,112
glioblastoma 23 | 5,792
osteosarcoma 21 | 7,950
adult high grade glioma 19 | 3,801
intraductal papillary-mucinous carcinoma (IPMC) 19 | 2,989
malignant mesothelioma 18 | 3,232
ependymoma 17 | 4,679
intraductal papillary-mucinous neoplasm (IPMN) 17 | 3,291
primitive neuroectodermal tumor 17 | 3,035
invasive ductal carcinoma 15 | 2,951
non-small cell lung cancer 15 | 2,890
adrenocortical carcinoma 14 | 1,428
lung adenocarcinoma 14 | 2,716
breast carcinoma 13 | 1,638
intraductal papillary-mucinous adenoma (IPMA) 13 | 2,955
pancreatic cancer 13 | 2,398
Cancer 12 | 2,499
oligodendroglioma 12 | 2,850
Atopic dermatitis 11 | 952
Endometriosis 11 | 540
Kidney cancer 11 | 2,613
astrocytic glioma 11 | 2,597
ductal carcinoma in situ 11 | 1,745
tuberculosis 11 | 2,010
Pick disease 10 | 1,894
colon cancer 10 | 1,478
interstitial cystitis 9 | 2,312
nasopharyngeal carcinoma 9 | 1,058
Astrocytoma, Pilocytic 8 | 3,081
Intellectual disability 8 | 1,016
Multiple myeloma 7 | 1,332
subependymal giant cell astrocytoma 7 | 2,287
Waldenstrons macroglobulinemia 6 | 765
gastric cancer 6 | 459
lung carcinoma 6 | 2,843
ulcerative colitis 6 | 1,819
Autosomal recessive predisposition 5 | 1,442
Epilepsy 5 | 792
cystic fibrosis 5 | 1,696
hepatocellular carcinoma 5 | 547
tuberculosis and treatment for 6 months 5 | 409
Dull intelligence 4 | 645
Liver Cirrhosis, Experimental 4 | 769
Liver cancer 4 | 604
Low intelligence 4 | 645
Mental Retardation 4 | 645
Mental deficiency 4 | 645
Optic Atrophy 4 | 242
Poor school performance 4 | 645
Short stature 4 | 531
Small head 4 | 374
acute quadriplegic myopathy 4 | 1,158
esophageal adenocarcinoma 4 | 737
group 4 medulloblastoma 4 | 1,855
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
pituitary cancer 4 | 1,972
primary Sjogren syndrome 4 | 735
spina bifida 4 | 1,074
Cataract 3 | 297
Duchenne muscular dystrophy 3 | 601
Melanoma 3 | 711
Rheumatoid arthritis 3 | 1,191
Schizophrenia 3 | 1,160
Seizures 3 | 596
active Crohn's disease 3 | 922
acute myeloid leukemia 3 | 783
astrocytoma 3 | 1,146
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 510
chronic rhinosinusitis 3 | 512
diabetes mellitus 3 | 1,728
juvenile dermatomyositis 3 | 1,187
non primary Sjogren syndrome sicca 3 | 891
pancreatic carcinoma 3 | 562
pediatric high grade glioma 3 | 1,064
Acquired scoliosis 2 | 281
Anteverted nostril 2 | 191
Arthritis, Juvenile 2 | 126
Becker muscular dystrophy 2 | 191
Bipolar Disorder 2 | 666
Brain Ischemia 2 | 110
Curvature of spine 2 | 282
Down syndrome 2 | 499
Endometrial cancer 2 | 311
Glaucoma 2 | 239
Juvenile arthritis 2 | 126
Lung Neoplasms 2 | 232
Polycystic ovary syndrome 2 | 360
Prostate cancer 2 | 175
cutaneous lupus erythematosus 2 | 1,057
gastric carcinoma 2 | 807
primary pancreatic ductal adenocarcinoma 2 | 1,109
progressive supranuclear palsy 2 | 676
urothelial carcinoma 2 | 318

Tissue

Blood and immune system 50 | 16,909
Digestive Tract 50 | 17,369
Endocrine System 50 | 18,159
Female tissues 50 | 17,400
Liver and Pancreas 50 | 16,750
Male tissues 50 | 17,142
Respiratory system 50 | 16,393
Skin and soft tissues 50 | 17,230
Urinary Tract 50 | 16,678
Nervous System 48 | 16,725
Cardiovascular System 46 | 15,192

Target Family

Non-IDG 30 | 12,091
Enzyme 11 | 4,145
Kinase 6 | 634
Epigenetic 3 | 242
Ion Channel 1 | 344

GO Component

mitotic spindle 51 | 51
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Mitotic spindle assembly checkpoint protein MAD1 MAD1L1 Tbio Non-IDG -1.17500 13.6 283
Dual specificity protein phosphatase CDC14C CDC14C Tdark Enzyme -0.37414 4.05 0
Sperm-associated antigen 5 SPAG5 Tbio Non-IDG -1.72743 51.4 136
Nuclear mitotic apparatus protein 1 NUMA1 Tbio Non-IDG -2.76544 575.8 235
Small kinetochore-associated protein KNSTRN Tbio Non-IDG -1.28291 21.4 32
Polycystin-2 PKD2 Tchem Ion Channel -2.63806 461.3 231
Heterogeneous nuclear ribonucleoprotein U HNRNPU Tbio Non-IDG -2.33813 207.8 169
Nucleoprotein TPR TPR Tbio Non-IDG -2.11491 135.6 161
Cytosolic carboxypeptidase-like protein 5 AGBL5 Tbio Enzyme -0.97543 10.5 132
YEATS domain-containing protein 2 YEATS2 Tbio Non-IDG -0.51547 3.19 61