Development Level

Tbio 117 | 11,445
Tchem 30 | 1,598
Tclin 8 | 613
Tdark 8 | 6,588

IMPC Phenotype

abnormal behavior 7 | 298
preweaning lethality, complete... 7 | 979
hyperactivity 6 | 148
decreased body weight 5 | 161
hypoactivity 5 | 132
abnormal bone structure 4 | 187
decreased vertical activity 4 | 208
preweaning lethality, incomple... 4 | 499
abnormal lens morphology 3 | 81
cataract 3 | 92
decreased body length 3 | 101
decreased bone mineral content 3 | 151
decreased bone mineral density 3 | 126
decreased circulating HDL chol... 3 | 68
decreased circulating choleste... 3 | 93
decreased circulating glucose ... 3 | 126
decreased circulating serum al... 3 | 82
decreased circulating total pr... 3 | 49
decreased lean body mass 3 | 135
decreased total body fat amoun... 3 | 207
increased lean body mass 3 | 172
abnormal cranium morphology 2 | 36
abnormal sleep behavior 2 | 70
abnormal tibia morphology 2 | 14
decreased circulating LDL chol... 2 | 38
decreased circulating aspartat... 2 | 34
decreased grip strength 2 | 116
decreased heart weight 2 | 27
decreased mean corpuscular vol... 2 | 79
decreased startle reflex 2 | 75
increased circulating bilirubi... 2 | 16
increased heart weight 2 | 62
increased mean corpuscular hem... 2 | 96
increased or absent threshold ... 2 | 101
increased startle reflex 2 | 112
increased total body fat amoun... 2 | 134
short tibia 2 | 97
thrombocytopenia 2 | 56
abnormal clavicle morphology 1 | 6
abnormal coat appearance 1 | 31
abnormal coat- hair morphology 1 | 19
abnormal femur morphology 1 | 14
abnormal gait 1 | 69
abnormal humerus morphology 1 | 11
abnormal joint morphology 1 | 23
abnormal maxilla morphology 1 | 17
abnormal pelvic girdle bone mo... 1 | 12
abnormal radius morphology 1 | 8
abnormal rib morphology 1 | 10
abnormal scapula morphology 1 | 3
abnormal snout morphology 1 | 23
abnormal tooth morphology 1 | 24
abnormal ulna morphology 1 | 8
abnormal vertebrae morphology 1 | 18
abnormal vibrissa morphology 1 | 25
abnormal vitreous body morphol... 1 | 10
absent mammary gland 1 | 1
absent startle reflex 1 | 24
aorta dilation 1 | 3
corneal opacity 1 | 32
decreased blood urea nitrogen ... 1 | 51
decreased circulating alkaline... 1 | 46
decreased circulating calcium ... 1 | 36
decreased circulating magnesiu... 1 | 13
decreased circulating phosphat... 1 | 27
decreased circulating potassiu... 1 | 20
decreased circulating triglyce... 1 | 79
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased lactate dehydrogenas... 1 | 16
decreased mean platelet volume 1 | 25
decreased prepulse inhibition 1 | 82
decreased total retina thickne... 1 | 17
edema 1 | 59
enlarged heart 1 | 210
female infertility 1 | 60
hydrometra 1 | 53
increased bone mineral content 1 | 108
increased circulating LDL chol... 1 | 13
increased circulating alkaline... 1 | 122
increased circulating glycerol... 1 | 9
increased circulating lipase l... 1 | 3
increased circulating phosphat... 1 | 26
increased circulating serum al... 1 | 22
increased circulating sodium l... 1 | 71
increased heart rate 1 | 23
increased hemoglobin content 1 | 45
increased red blood cell distr... 1 | 34
male infertility 1 | 123
mammalian phenotype 1 | 17
persistence of hyaloid vascula... 1 | 33
prolonged QT interval 1 | 38
shortened QT interval 1 | 4
small heart 1 | 10
small kidney 1 | 16
small ovary 1 | 1
small spleen 1 | 19
small superior vagus ganglion 1 | 74
small uterus 1 | 3
thin skin 1 | 2

Disease

ovarian cancer 94 | 8,520
Carcinoma 89 | 11,493
osteosarcoma 78 | 7,950
lung cancer 71 | 4,740
medulloblastoma, large-cell 70 | 6,241
atypical teratoid / rhabdoid tumor 56 | 5,112
glioblastoma 56 | 5,792
psoriasis 56 | 6,694
ependymoma 45 | 4,679
malignant mesothelioma 39 | 3,232
invasive ductal carcinoma 38 | 2,951
Cancer 37 | 2,499
group 3 medulloblastoma 35 | 4,104
adult high grade glioma 34 | 3,801
Breast cancer 33 | 3,578
non-small cell lung cancer 31 | 2,890
intraductal papillary-mucinous neoplasm (IPMN) 30 | 3,291
astrocytic glioma 29 | 2,597
lung adenocarcinoma 29 | 2,716
oligodendroglioma 29 | 2,850
tuberculosis 29 | 2,010
intraductal papillary-mucinous carcinoma (IPMC) 28 | 2,989
primitive neuroectodermal tumor 28 | 3,035
lung carcinoma 27 | 2,843
pancreatic cancer 27 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 27 | 1,962
Astrocytoma, Pilocytic 26 | 3,081
Multiple myeloma 25 | 1,332
Pick disease 25 | 1,894
intraductal papillary-mucinous adenoma (IPMA) 24 | 2,955
diabetes mellitus 23 | 1,728
ductal carcinoma in situ 23 | 1,745
ulcerative colitis 23 | 1,819
Alzheimer's disease 20 | 658
breast carcinoma 20 | 1,638
dermatomyositis 20 | 966
Schizophrenia 18 | 1,160
group 4 medulloblastoma 18 | 1,855
interstitial cystitis 18 | 2,312
pituitary cancer 18 | 1,972
Autosomal recessive predisposition 17 | 1,442
colon cancer 17 | 1,478
Kidney cancer 16 | 2,613
Obesity 16 | 678
Neurodegenerative disease 15 | 414
cystic fibrosis 15 | 1,696
pediatric high grade glioma 15 | 1,064
subependymal giant cell astrocytoma 15 | 2,287
active Crohn's disease 14 | 922
Liver Cirrhosis, Experimental 13 | 769
Parkinson's disease 13 | 392
acute quadriplegic myopathy 13 | 1,158
Rheumatoid arthritis 12 | 1,191
Waldenstrons macroglobulinemia 12 | 765
aldosterone-producing adenoma 12 | 665
Bipolar Disorder 11 | 666
Breast Neoplasms 11 | 445
Mammary Neoplasms 11 | 425
Multiple Sclerosis 11 | 540
Toxic encephalopathy 11 | 141
esophageal adenocarcinoma 11 | 737
juvenile dermatomyositis 11 | 1,187
medulloblastoma 11 | 720
Intellectual disability 10 | 1,016
Major Depressive Disorder 10 | 301
Optic Atrophy 10 | 242
active ulcerative colitis 10 | 764
acute myeloid leukemia 10 | 783
astrocytoma 10 | 1,146
primary Sjogren syndrome 10 | 735
primary pancreatic ductal adenocarcinoma 10 | 1,109
progressive supranuclear palsy 10 | 676
Atopic dermatitis 9 | 952
Epilepsy 9 | 792
Unipolar Depression 9 | 250
Vascular disease 9 | 319
adrenocortical carcinoma 9 | 1,428
cutaneous lupus erythematosus 9 | 1,057
gastric carcinoma 9 | 807
hereditary spastic paraplegia 9 | 318
nasopharyngeal carcinoma 9 | 1,058
non primary Sjogren syndrome sicca 9 | 891
Depressive disorder 8 | 409
Diabetes Mellitus, Experimental 8 | 108
Duchenne muscular dystrophy 8 | 601
Dull intelligence 8 | 645
Low intelligence 8 | 645
Melanoma 8 | 711
Mental Retardation 8 | 645
Mental deficiency 8 | 645
Muscle hypotonia 8 | 571
Poor school performance 8 | 645
Seizures 8 | 596
autosomal dominant Emery-Dreifuss muscular dystrophy 8 | 510
Chronic Lymphocytic Leukemia 7 | 262
Cognitive delay 7 | 608
Global developmental delay 7 | 608
Mental and motor retardation 7 | 608
Prostatic Neoplasms 7 | 495
gastric cancer 7 | 459

Tissue

Endocrine System 159 | 18,159
Blood and immune system 158 | 16,909
Digestive Tract 157 | 17,369
Female tissues 157 | 17,400
Skin and soft tissues 157 | 17,230
Liver and Pancreas 156 | 16,750
Male tissues 156 | 17,142
Nervous System 156 | 16,725
Urinary Tract 156 | 16,678
Cardiovascular System 155 | 15,192
Respiratory system 155 | 16,393

Target Family

Non-IDG 92 | 12,091
Enzyme 46 | 4,145
Kinase 14 | 634
Transporter 5 | 473
Epigenetic 2 | 242
Transcription Factor 2 | 1,400
GPCR 1 | 408
Nuclear Receptor 1 | 48

GO Component

mitochondrial outer membrane 163 | 163
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Phorbol-12-myristate-13-acetate-induced protein 1 PMAIP1 Tbio Non-IDG -2.70122 462.2 347
BRI3-binding protein BRI3BP Tbio Non-IDG -0.63682 5.24 115
Long-chain-fatty-acid--CoA ligase 5 ACSL5 Tbio Enzyme -1.98202 97.3 170
Myocilin MYOC Tbio Non-IDG -2.65916 482.8 169
Interferon alpha-inducible protein 27, mitochondrial IFI27 Tbio Non-IDG -1.51419 33.3 0
Protein misato homolog 1 MSTO1 Tbio Non-IDG -1.77593 58.1 65
Choline transporter-like protein 1 SLC44A1 Tbio Transporter -1.60796 43.9 212
Glycerol-3-phosphate acyltransferase 1, mitochondrial GPAM Tbio Enzyme -1.93041 83.4 177
Putative peripheral benzodiazepine receptor-related protein TSPO Tchem Non-IDG -3.08695 2284.2 212
1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon AGPAT5 Tbio Enzyme -0.79526 4.42 180