Development Level

Tdark 34 | 6,588
Tbio 18 | 11,445

IMPC Phenotype

preweaning lethality, complete... 8 | 979
embryonic lethality prior to o... 5 | 239
abnormal embryo size 3 | 220
embryonic growth retardation 3 | 106
embryonic lethality prior to t... 3 | 278
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal coat-hair pigmentatio... 1 | 64
abnormal heart morphology 1 | 162
abnormal lens morphology 1 | 81
abnormal spleen morphology 1 | 55
abnormal tail morphology 1 | 25
decreased circulating glucose ... 1 | 126
decreased vertical activity 1 | 208
enlarged heart 1 | 210
enlarged spleen 1 | 41
impaired pupillary reflex 1 | 26
increased fasted circulating g... 1 | 76

Disease

ovarian cancer 33 | 8,520
osteosarcoma 20 | 7,950
lung cancer 13 | 4,740
pancreatic ductal adenocarcinoma liver metastasis 12 | 1,962
Breast cancer 10 | 3,578
Carcinoma 9 | 11,493
non primary Sjogren syndrome sicca 9 | 891
Multiple myeloma 8 | 1,332
group 3 medulloblastoma 8 | 4,104
non-small cell lung cancer 8 | 2,890
psoriasis 8 | 6,694
acute myeloid leukemia 5 | 783
colon cancer 5 | 1,478
glioblastoma 5 | 5,792
medulloblastoma, large-cell 5 | 6,241
pediatric high grade glioma 5 | 1,064
astrocytic glioma 4 | 2,597
atypical teratoid / rhabdoid tumor 4 | 5,112
lung adenocarcinoma 4 | 2,716
Breast Neoplasms 3 | 445
Mammary Neoplasms 3 | 425
breast carcinoma 3 | 1,638
group 4 medulloblastoma 3 | 1,855
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
invasive ductal carcinoma 3 | 2,951
nasopharyngeal carcinoma 3 | 1,058
Brain glioma 2 | 7
Combined oxidative phosphorylation deficiency 2 | 14
Retinitis pigmentosa 4 2 | 38
active Crohn's disease 2 | 922
cystic fibrosis 2 | 1,696
dermatomyositis 2 | 966
diabetes mellitus 2 | 1,728
hereditary spastic paraplegia 2 | 318
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
lung carcinoma 2 | 2,843
primitive neuroectodermal tumor 2 | 3,035
Acquired metabolic disease 1 | 336
Adenocarcinoma of lung 1 | 142
Allergic rhinitis 1 | 94
Alzheimer's disease 1 | 658
Ankylosing spondylitis 1 | 140
Attention deficit hyperactivity disorder 1 | 278
Axonal neuropathy 1 | 27
Carcinoma, Squamous Cell 1 | 110
Cardiovascular system disease 1 | 246
Charcot-Marie-Tooth disease 1 | 62
DiGeorge syndrome 1 | 47
Diarrhea 1 | 253
Disease Models, Animal 1 | 155
Disease Progression 1 | 136
Dyslexia 1 | 43
Dyspnea 1 | 76
Elevated hepatic transaminases 1 | 81
Enamel caries 1 | 8
Failure to gain weight 1 | 365
Gaucher disease type 1 1 | 180
Gilles de la Tourette syndrome 1 | 47
Hepatic enzyme increased 1 | 81
Hepatomegaly 1 | 285
Hyper-beta-alaninemia 1 | 9
Hypertrophic Cardiomyopathy 1 | 117
Increased blood alanine 1 | 9
Increased serum alanine 1 | 9
Increased serum lactate 1 | 60
Leigh disease 1 | 100
Liver Dysfunction 1 | 99
Liver enzymes abnormal 1 | 81
Liver function test increased 1 | 81
Liver function tests abnormal finding 1 | 81
Melanoma 1 | 711
Mental Depression 1 | 333
Mitochondrial Encephalomyopathies 1 | 7
Mouth Neoplasms 1 | 55
Neurodegenerative disease 1 | 414
Ophthalmoplegia 1 | 106
Osteoarthritis 1 | 184
Osteoporosis 1 | 363
Paraplegia 1 | 74
Pediatric failure to thrive 1 | 365
Pick disease 1 | 1,894
Specific language impairment 1 | 34
Squamous cell carcinoma 1 | 129
Stomach Neoplasms 1 | 300
Subclinical abnormal liver function tests 1 | 81
Thrombophilia 1 | 38
Transaminases increased 1 | 81
Velocardiofacial syndrome 1 | 46
Waldenstrons macroglobulinemia 1 | 765
Wilson-Turner syndrome 1 | 14
adrenocortical carcinoma 1 | 1,428
adult high grade glioma 1 | 3,801
aldosterone-producing adenoma 1 | 665
hepatocellular carcinoma 1 | 547
inflammatory breast cancer 1 | 286
posterior fossa group B ependymoma 1 | 416
primary pancreatic ductal adenocarcinoma 1 | 1,109
tuberculosis 1 | 2,010
tuberculosis and treatment for 6 months 1 | 409

Tissue

Blood and immune system 51 | 16,909
Cardiovascular System 51 | 15,192
Digestive Tract 51 | 17,369
Endocrine System 51 | 18,159
Female tissues 51 | 17,400
Liver and Pancreas 51 | 16,750
Male tissues 51 | 17,142
Nervous System 51 | 16,725
Respiratory system 51 | 16,393
Skin and soft tissues 51 | 17,230
Urinary Tract 51 | 16,678

Target Family

Non-IDG 47 | 12,091
Enzyme 5 | 4,145

GO Component

mitochondrial large ribosomal ... 52 | 52
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
39S ribosomal protein L22, mitochondrial MRPL22 Tdark Non-IDG 0.70 0.21 64
39S ribosomal protein L11, mitochondrial MRPL11 Tdark Non-IDG -0.63555 3.41 198
39S ribosomal protein L49, mitochondrial MRPL49 Tbio Non-IDG -2.76367 555.1 76
39S ribosomal protein L45, mitochondrial MRPL45 Tdark Non-IDG 0.51 0.23 0
39S ribosomal protein L20, mitochondrial MRPL20 Tdark Non-IDG 1.23 0.05 48
39S ribosomal protein L32, mitochondrial MRPL32 Tdark Non-IDG 0.18 0.93 52
39S ribosomal protein L9, mitochondrial MRPL9 Tdark Non-IDG 1.00 0.05 133
39S ribosomal protein L14, mitochondrial MRPL14 Tdark Non-IDG 0.00000 79
39S ribosomal protein L19, mitochondrial MRPL19 Tbio Non-IDG -0.91803 8.21 130
39S ribosomal protein L51, mitochondrial MRPL51 Tdark Non-IDG -0.21560 1.59 106