Development Level

Tbio 56 | 11,445
Tdark 8 | 6,588
Tchem 6 | 1,598
Tclin 6 | 613

IMPC Phenotype

preweaning lethality, complete... 5 | 979
hypoactivity 3 | 132
thrombocytopenia 3 | 56
abnormal behavior 2 | 298
cataract 2 | 92
decreased leukocyte cell numbe... 2 | 73
decreased mean platelet volume 2 | 25
abnormal clavicle morphology 1 | 6
abnormal gait 1 | 69
abnormal lens morphology 1 | 81
abnormal lung morphology 1 | 26
abnormal maxilla morphology 1 | 17
abnormal rib morphology 1 | 10
abnormal seminal vesicle morph... 1 | 114
abnormal skin morphology 1 | 50
decreased bone mineral content 1 | 151
decreased circulating alkaline... 1 | 46
decreased circulating creatini... 1 | 39
decreased circulating phosphat... 1 | 27
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased circulating triglyce... 1 | 79
decreased fasted circulating g... 1 | 65
decreased food intake 1 | 13
decreased grip strength 1 | 116
decreased heart left ventricle... 1 | 28
decreased heart weight 1 | 27
decreased hemoglobin content 1 | 68
decreased large unstained cell... 1 | 11
decreased lymphocyte cell numb... 1 | 83
decreased neutrophil cell numb... 1 | 42
decreased prepulse inhibition 1 | 82
decreased red blood cell distr... 1 | 41
decreased respiratory quotient 1 | 16
decreased startle reflex 1 | 75
decreased total retina thickne... 1 | 17
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
enlarged lymph nodes 1 | 37
enlarged spleen 1 | 41
enlarged testis 1 | 6
increased blood urea nitrogen ... 1 | 48
increased circulating HDL chol... 1 | 80
increased circulating calcium ... 1 | 34
increased circulating choleste... 1 | 66
increased circulating phosphat... 1 | 26
increased circulating potassiu... 1 | 29
increased grip strength 1 | 41
increased heart weight 1 | 62
increased hemoglobin content 1 | 45
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
increased spleen weight 1 | 10
increased total body fat amoun... 1 | 134
long tibia 1 | 25
preweaning lethality, incomple... 1 | 499
small seminal vesicle 1 | 10
thin ventricular wall 1 | 24

Disease

ovarian cancer 44 | 8,520
osteosarcoma 38 | 7,950
lung cancer 28 | 4,740
Carcinoma 26 | 11,493
medulloblastoma, large-cell 25 | 6,241
glioblastoma 22 | 5,792
Breast cancer 19 | 3,578
psoriasis 19 | 6,694
adult high grade glioma 18 | 3,801
atypical teratoid / rhabdoid tumor 18 | 5,112
ependymoma 17 | 4,679
Autosomal recessive predisposition 15 | 1,442
group 3 medulloblastoma 15 | 4,104
Cancer 14 | 2,499
Multiple myeloma 14 | 1,332
diabetes mellitus 12 | 1,728
pancreatic ductal adenocarcinoma liver metastasis 12 | 1,962
Waldenstrons macroglobulinemia 11 | 765
astrocytic glioma 11 | 2,597
lung adenocarcinoma 11 | 2,716
malignant mesothelioma 11 | 3,232
non-small cell lung cancer 11 | 2,890
primitive neuroectodermal tumor 10 | 3,035
Neurodegenerative disease 9 | 414
group 4 medulloblastoma 9 | 1,855
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,291
non primary Sjogren syndrome sicca 9 | 891
Astrocytoma, Pilocytic 8 | 3,081
Parkinson's disease 8 | 392
Schizophrenia 8 | 1,160
oligodendroglioma 8 | 2,850
tuberculosis 8 | 2,010
invasive ductal carcinoma 7 | 2,951
Cognitive delay 6 | 608
Global developmental delay 6 | 608
Intellectual disability 6 | 1,016
Leigh disease 6 | 100
Mental and motor retardation 6 | 608
Rheumatoid arthritis 6 | 1,191
acute myeloid leukemia 6 | 783
astrocytoma 6 | 1,146
colon cancer 6 | 1,478
interstitial cystitis 6 | 2,312
ulcerative colitis 6 | 1,819
Alzheimer's disease 5 | 658
Dull intelligence 5 | 645
Dystonia 5 | 164
Epilepsy 5 | 792
Failure to gain weight 5 | 365
Kidney disease 5 | 430
Low intelligence 5 | 645
Mental Retardation 5 | 645
Mental deficiency 5 | 645
Neuropathy 5 | 261
Obesity 5 | 678
Optic Atrophy 5 | 242
Pediatric failure to thrive 5 | 365
Pick disease 5 | 1,894
Poor school performance 5 | 645
Seizures 5 | 596
Sensorineural Hearing Loss (disorder) 5 | 284
aldosterone-producing adenoma 5 | 665
cutaneous lupus erythematosus 5 | 1,057
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
pancreatic cancer 5 | 2,398
pituitary cancer 5 | 1,972
subependymal giant cell astrocytoma 5 | 2,287
Anemia 4 | 365
Brain Ischemia 4 | 110
Brain disease 4 | 96
Carcinoma, Hepatocellular 4 | 228
Cerebellar Ataxia 4 | 304
Deafness dystonia syndrome 4 | 21
Diabetes mellitus type 2 4 | 69
Disease Progression 4 | 136
Down syndrome 4 | 499
Hyperreflexia 4 | 209
Liver carcinoma 4 | 240
Major Depressive Disorder 4 | 301
Muscle Spasticity 4 | 195
Necrosis 4 | 53
Neurogenic Muscular Atrophy 4 | 139
Neurogenic muscle atrophy, especially in the lower limbs 4 | 139
Polycystic ovary syndrome 4 | 360
Skeletal muscle atrophy 4 | 139
Toxic encephalopathy 4 | 141
Treatment Refractory Type 2 Diabetes Mellitus 4 | 53
Vomiting 4 | 116
adrenocortical carcinoma 4 | 1,428
breast carcinoma 4 | 1,638
cystic fibrosis 4 | 1,696
dermatomyositis 4 | 966
ductal carcinoma in situ 4 | 1,745
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
lung carcinoma 4 | 2,843
muscle degeneration 4 | 139
nasopharyngeal carcinoma 4 | 1,058
Atopic dermatitis 3 | 952
Bipolar Disorder 3 | 666
fibroadenoma 3 | 559

Tissue

Digestive Tract 75 | 17,369
Endocrine System 75 | 18,159
Female tissues 75 | 17,400
Liver and Pancreas 75 | 16,750
Male tissues 75 | 17,142
Nervous System 75 | 16,725
Skin and soft tissues 75 | 17,230
Blood and immune system 74 | 16,909
Respiratory system 74 | 16,393
Urinary Tract 74 | 16,678
Cardiovascular System 72 | 15,192

Target Family

Enzyme 37 | 4,145
Non-IDG 31 | 12,091
Kinase 7 | 634
Epigenetic 1 | 242

GO Component

mitochondrial intermembrane sp... 76 | 76
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..