Development Level

Tbio 103 | 11,445
Tchem 23 | 1,598
Tdark 14 | 6,588
Tclin 1 | 613

Collection

Kinase: IDG Consortium (Target... 1 | 125
RFA-RM-18-021 1 | 328

IMPC Phenotype

preweaning lethality, complete... 14 | 979
preweaning lethality, incomple... 7 | 499
embryonic lethality prior to o... 6 | 239
embryonic lethality prior to t... 5 | 278
increased total body fat amoun... 5 | 134
short tibia 5 | 97
abnormal behavior 4 | 298
abnormal bone structure 4 | 187
decreased total body fat amoun... 4 | 207
increased circulating HDL chol... 4 | 80
increased circulating alkaline... 4 | 122
abnormal embryo size 3 | 220
abnormal retina morphology 3 | 71
decreased bone mineral content 3 | 151
decreased bone mineral density 3 | 126
decreased circulating serum al... 3 | 82
decreased lean body mass 3 | 135
increased bone mineral content 3 | 108
increased lean body mass 3 | 172
increased mean corpuscular hem... 3 | 96
increased neutrophil cell numb... 3 | 46
prenatal lethality prior to he... 3 | 87
abnormal coat-hair pigmentatio... 2 | 64
abnormal cranium morphology 2 | 36
abnormal kidney morphology 2 | 65
abnormal skin morphology 2 | 50
cataract 2 | 92
decreased body length 2 | 101
decreased caudal vertebrae num... 2 | 53
decreased circulating HDL chol... 2 | 68
decreased grip strength 2 | 116
decreased lymphocyte cell numb... 2 | 83
decreased mean corpuscular vol... 2 | 79
decreased red blood cell distr... 2 | 41
decreased startle reflex 2 | 75
embryonic growth retardation 2 | 106
increased bone mineral density 2 | 72
increased circulating choleste... 2 | 66
increased fasted circulating g... 2 | 76
increased hematocrit 2 | 46
increased leukocyte cell numbe... 2 | 47
increased mean corpuscular vol... 2 | 92
increased or absent threshold ... 2 | 101
increased spleen weight 2 | 10
thrombocytopenia 2 | 56
abnormal body wall morphology 1 | 9
abnormal embryo turning 1 | 31
abnormal epididymis morphology 1 | 42
abnormal lens morphology 1 | 81
abnormal lip morphology 1 | 2
abnormal pancreas morphology 1 | 13
abnormal pelvic girdle bone mo... 1 | 12
abnormal pericardium morpholog... 1 | 26
abnormal placenta size 1 | 20
abnormal seminal vesicle morph... 1 | 114
abnormal skin coloration 1 | 25
abnormal spleen morphology 1 | 55
abnormal testis morphology 1 | 43
abnormal vertebrae morphology 1 | 18
absent startle reflex 1 | 24
cardiovascular system phenotyp... 1 | 36
decreased brain size 1 | 4
decreased circulating calcium ... 1 | 36
decreased circulating chloride... 1 | 30
decreased circulating choleste... 1 | 93
decreased circulating creatini... 1 | 39
decreased circulating insulin ... 1 | 76
decreased circulating potassiu... 1 | 20
decreased eosinophil cell numb... 1 | 24
decreased fasted circulating g... 1 | 65
decreased heart left ventricle... 1 | 28
decreased neutrophil cell numb... 1 | 42
decreased threshold for audito... 1 | 26
edema 1 | 59
enlarged epididymis 1 | 31
enlarged lymph nodes 1 | 37
enlarged spleen 1 | 41
female infertility 1 | 60
hemorrhage 1 | 23
hypoactivity 1 | 132
impaired righting response 1 | 26
increased blood urea nitrogen ... 1 | 48
increased body weight 1 | 25
increased circulating chloride... 1 | 41
increased exploration in new e... 1 | 8
increased heart rate variabili... 1 | 7
increased heart weight 1 | 62
increased hemoglobin content 1 | 45
increased mean platelet volume 1 | 45
increased monocyte cell number 1 | 63
increased startle reflex 1 | 112
prenatal lethality 1 | 28
shortened RR interval 1 | 17
small liver 1 | 8
small lung 1 | 5
small spleen 1 | 19
small superior vagus ganglion 1 | 74
small testis 1 | 58
tremors 1 | 39
vertebral fusion 1 | 23

Disease

ovarian cancer 95 | 8,520
Carcinoma 94 | 11,493
medulloblastoma, large-cell 73 | 6,241
osteosarcoma 73 | 7,950
glioblastoma 71 | 5,792
atypical teratoid / rhabdoid tumor 65 | 5,112
lung cancer 60 | 4,740
psoriasis 56 | 6,694
group 3 medulloblastoma 53 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 48 | 3,291
Breast cancer 47 | 3,578
adult high grade glioma 47 | 3,801
primitive neuroectodermal tumor 45 | 3,035
ependymoma 43 | 4,679
invasive ductal carcinoma 43 | 2,951
intraductal papillary-mucinous carcinoma (IPMC) 41 | 2,989
malignant mesothelioma 39 | 3,232
non-small cell lung cancer 36 | 2,890
Cancer 35 | 2,499
pancreatic cancer 35 | 2,398
Astrocytoma, Pilocytic 32 | 3,081
lung adenocarcinoma 32 | 2,716
Kidney cancer 30 | 2,613
adrenocortical carcinoma 29 | 1,428
breast carcinoma 29 | 1,638
colon cancer 29 | 1,478
ductal carcinoma in situ 28 | 1,745
oligodendroglioma 27 | 2,850
Multiple myeloma 24 | 1,332
Atopic dermatitis 22 | 952
Endometriosis 21 | 540
intraductal papillary-mucinous adenoma (IPMA) 21 | 2,955
lung carcinoma 21 | 2,843
astrocytic glioma 20 | 2,597
interstitial cystitis 19 | 2,312
Intellectual disability 18 | 1,016
subependymal giant cell astrocytoma 18 | 2,287
ulcerative colitis 18 | 1,819
nasopharyngeal carcinoma 17 | 1,058
pancreatic ductal adenocarcinoma liver metastasis 17 | 1,962
Autosomal recessive predisposition 16 | 1,442
Pick disease 16 | 1,894
Waldenstrons macroglobulinemia 16 | 765
acute quadriplegic myopathy 16 | 1,158
group 4 medulloblastoma 16 | 1,855
tuberculosis 16 | 2,010
primary pancreatic ductal adenocarcinoma 15 | 1,109
Dull intelligence 13 | 645
Low intelligence 13 | 645
Mental Retardation 13 | 645
Mental deficiency 13 | 645
Poor school performance 13 | 645
astrocytoma 13 | 1,146
Rheumatoid arthritis 12 | 1,191
diabetes mellitus 12 | 1,728
pediatric high grade glioma 12 | 1,064
primary Sjogren syndrome 12 | 735
progressive supranuclear palsy 12 | 676
juvenile dermatomyositis 11 | 1,187
pituitary cancer 11 | 1,972
spina bifida 11 | 1,074
dermatomyositis 10 | 966
esophageal adenocarcinoma 9 | 737
non primary Sjogren syndrome sicca 9 | 891
Cataract 8 | 297
Nystagmus 8 | 317
Obesity 8 | 678
gastric carcinoma 8 | 807
posterior fossa group A ependymoma 8 | 468
Bipolar Disorder 7 | 666
Breast Neoplasms 7 | 445
Duchenne muscular dystrophy 7 | 601
Lens Opacities 7 | 231
Liver Cirrhosis, Experimental 7 | 769
Mammary Neoplasms 7 | 425
Schizophrenia 7 | 1,160
active Crohn's disease 7 | 922
hereditary spastic paraplegia 7 | 318
medulloblastoma 7 | 720
Broad flat nasal bridge 6 | 236
Cognitive delay 6 | 608
Down syndrome 6 | 499
Glaucoma 6 | 239
Global developmental delay 6 | 608
Mental and motor retardation 6 | 608
Microcephaly 6 | 166
Nasal bridge wide 6 | 236
Neurodegenerative disease 6 | 414
Retinitis Pigmentosa 6 | 226
Small head 6 | 374
Vascular disease 6 | 319
acute myeloid leukemia 6 | 783
cutaneous lupus erythematosus 6 | 1,057
cystic fibrosis 6 | 1,696
sonic hedgehog group medulloblastoma 6 | 467
tuberculosis and treatment for 6 months 6 | 409
aldosterone-producing adenoma 5 | 665
autosomal dominant Emery-Dreifuss muscular dystrophy 5 | 510
hepatocellular carcinoma 5 | 547
pancreatic carcinoma 5 | 562

Tissue

Blood and immune system 141 | 16,909
Endocrine System 141 | 18,159
Digestive Tract 140 | 17,369
Female tissues 140 | 17,400
Liver and Pancreas 140 | 16,750
Male tissues 140 | 17,142
Nervous System 140 | 16,725
Respiratory system 140 | 16,393
Skin and soft tissues 140 | 17,230
Urinary Tract 140 | 16,678
Cardiovascular System 137 | 15,192

Target Family

Non-IDG 94 | 12,091
Enzyme 29 | 4,145
Kinase 13 | 634
Epigenetic 2 | 242
Ion Channel 1 | 344
Transcription Factor 1 | 1,400
Transporter 1 | 473

GO Component

midbody 141 | 141
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability