Development Level

Tbio 43 | 11,445
Tchem 9 | 1,598
Tclin 5 | 613
Tdark 1 | 6,588

IMPC Phenotype

preweaning lethality, complete... 4 | 979
absent pinna reflex 3 | 23
decreased grip strength 3 | 116
embryonic lethality prior to t... 3 | 278
hyperactivity 3 | 148
increased circulating sodium l... 3 | 71
increased or absent threshold ... 3 | 101
abnormal behavior 2 | 298
abnormal embryo size 2 | 220
abnormal vibrissa morphology 2 | 25
decreased body weight 2 | 161
decreased circulating amylase ... 2 | 28
decreased circulating insulin ... 2 | 76
decreased circulating triglyce... 2 | 79
embryonic lethality prior to o... 2 | 239
impaired righting response 2 | 26
increased circulating chloride... 2 | 41
increased lean body mass 2 | 172
increased mean platelet volume 2 | 45
preweaning lethality, incomple... 2 | 499
stereotypic behavior 2 | 3
trunk curl 2 | 16
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal embryo turning 1 | 31
abnormal locomotor activation 1 | 16
abnormal nail morphology 1 | 8
abnormal pericardium morpholog... 1 | 26
abnormal retina morphology 1 | 71
abnormal tibia morphology 1 | 14
abnormal whole-body plethysmog... 1 | 4
absent startle reflex 1 | 24
decreased body length 1 | 101
decreased circulating bilirubi... 1 | 19
decreased circulating creatini... 1 | 39
decreased circulating glucose ... 1 | 126
decreased circulating potassiu... 1 | 20
decreased fasted circulating g... 1 | 65
decreased hemoglobin content 1 | 68
decreased lactate dehydrogenas... 1 | 16
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular vol... 1 | 79
decreased prepulse inhibition 1 | 82
decreased threshold for audito... 1 | 26
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
female infertility 1 | 60
hydrometra 1 | 53
hypoactivity 1 | 132
improved glucose tolerance 1 | 79
increased blood urea nitrogen ... 1 | 48
increased bone mineral content 1 | 108
increased circulating alkaline... 1 | 122
increased hemoglobin content 1 | 45
increased mean corpuscular hem... 1 | 96
increased monocyte cell number 1 | 63
increased thermal nociceptive ... 1 | 9
increased total body fat amoun... 1 | 134
increased vertical activity 1 | 24
limb grasping 1 | 41
persistence of hyaloid vascula... 1 | 33
small adrenal glands 1 | 16
small lymph nodes 1 | 1
small superior vagus ganglion 1 | 74
tremors 1 | 39

Disease

Carcinoma 44 | 11,493
ovarian cancer 35 | 8,520
osteosarcoma 26 | 7,950
psoriasis 25 | 6,694
medulloblastoma, large-cell 22 | 6,241
ependymoma 20 | 4,679
glioblastoma 20 | 5,792
Breast cancer 19 | 3,578
Cancer 19 | 2,499
lung cancer 19 | 4,740
atypical teratoid / rhabdoid tumor 18 | 5,112
lung adenocarcinoma 18 | 2,716
lung carcinoma 17 | 2,843
non-small cell lung cancer 16 | 2,890
intraductal papillary-mucinous adenoma (IPMA) 15 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 15 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 15 | 3,291
oligodendroglioma 15 | 2,850
Kidney cancer 14 | 2,613
group 3 medulloblastoma 14 | 4,104
invasive ductal carcinoma 14 | 2,951
ulcerative colitis 14 | 1,819
ductal carcinoma in situ 13 | 1,745
interstitial cystitis 13 | 2,312
pancreatic cancer 13 | 2,398
astrocytic glioma 12 | 2,597
malignant mesothelioma 12 | 3,232
pituitary cancer 12 | 1,972
Autosomal recessive predisposition 11 | 1,442
adult high grade glioma 11 | 3,801
breast carcinoma 11 | 1,638
colon cancer 11 | 1,478
primitive neuroectodermal tumor 11 | 3,035
Astrocytoma, Pilocytic 10 | 3,081
pancreatic ductal adenocarcinoma liver metastasis 10 | 1,962
Intellectual disability 8 | 1,016
Nonsyndromic deafness 8 | 142
Obesity 8 | 678
Sensorineural Hearing Loss (disorder) 8 | 284
cystic fibrosis 8 | 1,696
diabetes mellitus 8 | 1,728
group 4 medulloblastoma 8 | 1,855
Down syndrome 7 | 499
Duchenne muscular dystrophy 7 | 601
Dull intelligence 7 | 645
Liver Cirrhosis, Experimental 7 | 769
Low intelligence 7 | 645
Melanoma 7 | 711
Mental Retardation 7 | 645
Mental deficiency 7 | 645
Pick disease 7 | 1,894
Poor school performance 7 | 645
Skin cancer 7 | 469
adrenocortical carcinoma 7 | 1,428
pancreatic carcinoma 7 | 562
tuberculosis 7 | 2,010
Schizophrenia 6 | 1,160
autosomal dominant Emery-Dreifuss muscular dystrophy 6 | 510
fibroadenoma 6 | 559
Asthma 5 | 385
Atopic dermatitis 5 | 952
Cataract 5 | 297
Electroretinogram abnormal 5 | 95
Glaucoma 5 | 239
Lens Opacities 5 | 231
Multiple Sclerosis 5 | 540
Prostatic Neoplasms 5 | 495
Retinitis Pigmentosa 5 | 226
Sensorineural hearing loss 5 | 106
acute quadriplegic myopathy 5 | 1,158
astrocytoma 5 | 1,146
esophageal adenocarcinoma 5 | 737
spina bifida 5 | 1,074
subependymal giant cell astrocytoma 5 | 2,287
Abnormal vision 4 | 52
Atypical scarring of skin 4 | 62
Blindness 4 | 88
Broad flat nasal bridge 4 | 236
Cholestasis 4 | 155
Cognitive delay 4 | 608
Degenerative polyarthritis 4 | 115
Diabetic retinopathy 4 | 56
Global developmental delay 4 | 608
High-grade hypermetropia 4 | 24
Hypertension 4 | 396
Mental and motor retardation 4 | 608
Nasal bridge wide 4 | 236
Neurofibromatosis 4 | 40
Night Blindness 4 | 101
Osteoarthritis 4 | 184
Osteoporosis 4 | 363
Renal Cell Carcinoma 4 | 214
Short stature 4 | 531
Usher syndrome 4 | 32
aldosterone-producing adenoma 4 | 665
chronic rhinosinusitis 4 | 512
hepatocellular carcinoma 4 | 547
juvenile dermatomyositis 4 | 1,187
sonic hedgehog group medulloblastoma 4 | 467
acute myeloid leukemia 3 | 783

Tissue

Male tissues 57 | 17,142
Digestive Tract 56 | 17,369
Endocrine System 56 | 18,159
Female tissues 55 | 17,400
Liver and Pancreas 55 | 16,750
Skin and soft tissues 55 | 17,230
Blood and immune system 54 | 16,909
Urinary Tract 54 | 16,678
Nervous System 53 | 16,725
Respiratory system 51 | 16,393
Cardiovascular System 46 | 15,192

Target Family

Non-IDG 35 | 12,091
Enzyme 13 | 4,145
Kinase 3 | 634
Transporter 3 | 473
Ion Channel 2 | 344
GPCR 1 | 408
Transcription Factor 1 | 1,400

GO Component

microvillus 58 | 58
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Glutaredoxin domain-containing cysteine-rich protein 2 GRXCR2 Tbio Non-IDG 0.00000 1.00 14
Harmonin USH1C Tbio Non-IDG -2.10689 124.7 188
Moesin MSN Tbio Non-IDG -2.61389 361.7 550
Glutaredoxin domain-containing cysteine-rich protein 1 GRXCR1 Tdark Non-IDG -0.45230 3.09 43
Ras GTPase-activating-like protein IQGAP2 IQGAP2 Tbio Enzyme -1.40687 25.2 146
Ankyrin repeat and SAM domain-containing protein 4B ANKS4B Tbio Non-IDG -0.12494 1.58 59
Unconventional myosin-VIIa MYO7A Tbio Non-IDG -2.14713 133.5 129
Bardet-Biedl syndrome 2 protein BBS2 Tbio Non-IDG -2.84516 693.9 69
TBC1 domain family member 10A TBC1D10A Tbio Non-IDG -0.65759 0.00000 99
Formin-2 FMN2 Tbio Non-IDG -1.72748 52.6 96