Development Level

Tbio 41 | 10,625
Tchem 10 | 1,890
Tclin 3 | 602
Tdark 1 | 7,003

IMPC Term

increased or absent threshold ... 4 | 128
absent pinna reflex 3 | 21
decreased grip strength 3 | 123
increased circulating chloride... 3 | 43
increased circulating sodium l... 3 | 71
preweaning lethality, complete... 3 | 633
abnormal embryo size 2 | 112
abnormal vibrissa morphology 2 | 17
decreased body length 2 | 108
decreased circulating HDL chol... 2 | 77
decreased circulating amylase ... 2 | 24
decreased circulating choleste... 2 | 85
decreased circulating glucose ... 2 | 121
decreased circulating insulin ... 2 | 75
decreased circulating triglyce... 2 | 83
decreased prepulse inhibition 2 | 52
embryonic lethality prior to o... 2 | 148
embryonic lethality prior to t... 2 | 187
hyperactivity 2 | 108
impaired righting response 2 | 19
preweaning lethality, incomple... 2 | 260
stereotypic behavior 2 | 3
trunk curl 2 | 15
abnormal QRS complex 1 | 25
abnormal behavior 1 | 226
abnormal bone mineralization 1 | 55
abnormal bone structure 1 | 131
abnormal embryo turning 1 | 15
abnormal glucose homeostasis 1 | 5
abnormal locomotor activation 1 | 26
abnormal nail morphology 1 | 7
abnormal respiratory quotient 1 | 9
abnormal retinal pigmentation 1 | 61
abnormal tibia morphology 1 | 14
absent startle reflex 1 | 15
decreased NK T cell number 1 | 28
decreased body weight 1 | 174
decreased circulating free fat... 1 | 39
decreased circulating glycerol... 1 | 19
decreased circulating potassiu... 1 | 17
decreased fasted circulating g... 1 | 49
decreased hemoglobin content 1 | 53
decreased lactate dehydrogenas... 1 | 14
decreased lean body mass 1 | 195
decreased mean corpuscular hem... 1 | 34
decreased mean corpuscular vol... 1 | 50
decreased memory-marker CD4-ne... 1 | 4
decreased rib number 1 | 59
decreased startle reflex 1 | 48
decreased total body fat amoun... 1 | 186
female infertility 1 | 34
hypoactivity 1 | 89
improved glucose tolerance 1 | 56
increased NK T cell number 1 | 11
increased blood urea nitrogen ... 1 | 44
increased bone mineral content 1 | 92
increased circulating alkaline... 1 | 119
increased hemoglobin content 1 | 45
increased lean body mass 1 | 107
increased mean corpuscular hem... 1 | 93
increased mean platelet volume 1 | 19
increased rib number 1 | 41
limb grasping 1 | 35
persistence of hyaloid vascula... 1 | 22
small adrenal glands 1 | 15
small lymph nodes 1 | 1

Disease

ovarian cancer 33 | 8,484
osteosarcoma 24 | 7,933
psoriasis 23 | 6,685
medulloblastoma, large-cell 21 | 6,234
glioblastoma 17 | 5,572
lung adenocarcinoma 17 | 2,713
lung cancer 16 | 4,466
lung carcinoma 16 | 2,844
Breast cancer 15 | 3,094
non-small cell lung cancer 15 | 2,798
atypical teratoid / rhabdoid tumor 14 | 4,369
intraductal papillary-mucinous adenoma (IPMA) 14 | 2,956
intraductal papillary-mucinous neoplasm (IPMN) 14 | 3,289
oligodendroglioma 14 | 2,849
Cancer 13 | 2,346
intraductal papillary-mucinous carcinoma (IPMC) 13 | 2,988
invasive ductal carcinoma 13 | 2,950
ulcerative colitis 13 | 2,087
ductal carcinoma in situ 12 | 1,745
ependymoma 12 | 2,514
interstitial cystitis 12 | 2,299
pancreatic cancer 12 | 2,300
Carcinoma 11 | 2,147
malignant mesothelioma 11 | 3,162
astrocytic glioma 10 | 2,241
breast carcinoma 10 | 1,614
colon cancer 10 | 1,475
pituitary cancer 10 | 1,972
primitive neuroectodermal tumor 10 | 3,031
group 4 medulloblastoma 9 | 1,875
pancreatic ductal adenocarcinoma liver metastasis 9 | 1,795
pediatric high grade glioma 9 | 2,712
Nonsyndromic deafness 8 | 121
diabetes mellitus 8 | 1,663
pilocytic astrocytoma 8 | 3,086
sonic hedgehog group medulloblastoma 8 | 1,482
Down syndrome 7 | 548
Sensorineural hearing loss 7 | 107
cystic fibrosis 7 | 1,665
medulloblastoma 7 | 1,524
pancreatic carcinoma 7 | 567
posterior fossa group B ependymoma 7 | 1,530
Duchenne muscular dystrophy 6 | 602
Pick disease 6 | 1,893
Retinitis pigmentosa 6 | 153
adrenocortical carcinoma 6 | 1,427
astrocytoma 6 | 1,493
fibroadenoma 6 | 557
tuberculosis 6 | 1,557
Multiple Sclerosis 5 | 498
Obesity 5 | 616
Prostatic Neoplasms 5 | 471
Usher syndrome 5 | 34
acute quadriplegic myopathy 5 | 1,157
adult high grade glioma 5 | 2,148
atypical teratoid/rhabdoid tumor 5 | 1,095
autosomal dominant Emery-Dreifuss muscular dystrophy 5 | 499
esophageal adenocarcinoma 5 | 737
Asthma 4 | 349
Blindness 4 | 84
Degenerative polyarthritis 4 | 93
aldosterone-producing adenoma 4 | 664
chronic rhinosinusitis 4 | 512
gastric carcinoma 4 | 832
glioblastoma multiforme 4 | 347
hepatocellular carcinoma 4 | 532
juvenile dermatomyositis 4 | 1,189
spina bifida 4 | 1,064
subependymal giant cell astrocytoma 4 | 2,287
Alzheimer's disease 3 | 644
Atherosclerosis 3 | 275
Atopic dermatitis 3 | 944
Becker muscular dystrophy 3 | 187
Cerebrovascular disease 3 | 231
Cholestasis 3 | 93
Congenital nystagmus 3 | 26
Coronary artery disease 3 | 240
Diabetic Retinopathy 3 | 53
Hypertension 3 | 287
Hypertensive disease 3 | 193
Intellectual disability 3 | 573
Liver carcinoma 3 | 217
Multiple myeloma 3 | 1,327
Neurofibromatosis 3 | 37
Renal Cell Carcinoma 3 | 199
Rheumatoid Arthritis 3 | 1,160
Schizophrenia 3 | 501
mucosa-associated lymphoid tissue lymphoma 3 | 480
nephrosclerosis 3 | 329
posterior fossa group A ependymoma 3 | 1,511
primary pancreatic ductal adenocarcinoma 3 | 1,271
progressive supranuclear palsy 3 | 674
Heart disease 2 | 279
Hypersensitivity reaction type II disease 2 | 235
Myocardial Ischemia 2 | 169
Polycystic Ovary Syndrome 2 | 332
active Crohn's disease 2 | 918
acute myeloid leukemia 2 | 780
chronic lymphosyte leukemia 2 | 232
dermatomyositis 2 | 933

Tissue

Digestive Tract 55 | 18,473
Endocrine System 55 | 18,512
Female tissues 55 | 18,647
Nervous System 55 | 18,561
Urinary Tract 55 | 18,444
Liver and Pancreas 54 | 18,136
Skin and soft tissues 54 | 18,115
Blood and immune system 53 | 17,995
Cardiovascular System 53 | 17,958
Respiratory system 52 | 17,484
Male tissues 51 | 17,969

Target Family

Non-IDG 34 | 11,971
Enzyme 12 | 4,146
Transporter 3 | 473
Ion Channel 2 | 341
Kinase 2 | 634
GPCR 1 | 406
Transcription Factor 1 | 1,400

GO Component

microvillus 55 | 55
nucleus 5,107 | 5,107
cytoplasm 4,985 | 4,985
plasma membrane 4,118 | 4,118
integral component of membrane 3,679 | 3,679
cytosol 3,265 | 3,265
extracellular exosome 2,758 | 2,758
nucleoplasm 2,717 | 2,717
membrane 1,906 | 1,906
extracellular region 1,493 | 1,493
integral component of plasma m... 1,406 | 1,406
extracellular space 1,304 | 1,304
mitochondrion 1,231 | 1,231
Golgi apparatus 864 | 864
endoplasmic reticulum 859 | 859
endoplasmic reticulum membrane 848 | 848
nucleolus 815 | 815
Golgi membrane 659 | 659
perinuclear region of cytoplas... 611 | 611
cell surface 594 | 594
intracellular 548 | 548
intracellular membrane-bounded... 537 | 537
cell junction 451 | 451
mitochondrial inner membrane 425 | 425
centrosome 409 | 409
focal adhesion 383 | 383
protein complex 355 | 355
cytoskeleton 343 | 343
dendrite 329 | 329
mitochondrial matrix 322 | 322
cell-cell adherens junction 307 | 307
neuronal cell body 303 | 303
microtubule 294 | 294
lysosomal membrane 278 | 278
apical plasma membrane 277 | 277
proteinaceous extracellular ma... 244 | 244
neuron projection 229 | 229
nuclear membrane 218 | 218
early endosome 217 | 217
axon 214 | 214
lysosome 210 | 210
endosome 208 | 208
actin cytoskeleton 205 | 205
external side of plasma membra... 205 | 205
postsynaptic membrane 204 | 204
extracellular matrix 198 | 198
nuclear speck 197 | 197
membrane raft 196 | 196
endoplasmic reticulum lumen 192 | 192
transcription factor complex 184 | 184
endosome membrane 182 | 182
early endosome membrane 180 | 180
basolateral plasma membrane 174 | 174
nuclear chromatin 169 | 169
synapse 166 | 166
cell-cell junction 161 | 161
nuclear envelope 156 | 156
lamellipodium 153 | 153
mitochondrial outer membrane 148 | 148
blood microparticle 147 | 147
myelin sheath 144 | 144
postsynaptic density 144 | 144
cytoplasmic vesicle 143 | 143
microtubule organizing center 137 | 137
cytoplasmic, membrane-bounded ... 132 | 132
ER to Golgi transport vesicle ... 131 | 131
microtubule cytoskeleton 127 | 127
receptor complex 127 | 127
phagocytic vesicle membrane 126 | 126
cytoplasmic vesicle membrane 125 | 125
midbody 125 | 125
trans-Golgi network 124 | 124
cell cortex 119 | 119
cilium 118 | 118
late endosome 116 | 116
spindle 116 | 116
intracellular ribonucleoprotei... 114 | 114
vesicle 112 | 112
Z disc 110 | 110
bicellular tight junction 110 | 110
anchored component of membrane 109 | 109
growth cone 109 | 109
integral component of lumenal ... 108 | 108
late endosome membrane 107 | 107
endomembrane system 106 | 106
centriole 105 | 105
recycling endosome 104 | 104
spindle pole 104 | 104
perikaryon 103 | 103
integral component of endoplas... 101 | 101
intermediate filament 101 | 101
melanosome 101 | 101
chromosome 100 | 100
dendritic spine 99 | 99
ubiquitin ligase complex 99 | 99
peroxisome 98 | 98
nuclear matrix 97 | 97
PML body 94 | 94
Golgi lumen 93 | 93
keratin filament 93 | 93
trans-Golgi network membrane 92 | 92

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
V-type proton ATPase catalytic subunit A ATP6V1A Tbio Enzyme -1.80191 64.7 120
Ileal sodium/bile acid cotransporter SLC10A2 Tchem Transporter -2.60727 417.5 121
CD302 antigen CD302 Tbio Non-IDG -1.66778 46.5 120
Radixin RDX Tbio Non-IDG -2.45592 216.9 310
V-type proton ATPase subunit E 1 ATP6V1E1 Tbio Enzyme -0.98803 10.3 111
Formin-2 FMN2 Tbio Non-IDG -1.68628 51.8 92
Gastric intrinsic factor GIF Tbio Non-IDG -3.18880 1504.0 135
Harmonin USH1C Tbio Non-IDG -2.04033 115.8 173
Moesin MSN Tbio Non-IDG -2.57842 339.5 426
V-type proton ATPase subunit B, kidney isoform ATP6V1B1 Tchem Enzyme -1.64875 40.5 209