Development Level

Tbio 81 | 11,445
Tchem 22 | 1,598
Tdark 22 | 6,588
Tclin 9 | 613

Collection

Kinase: IDG Consortium (Comple... 2 | 37
Kinase: IDG Consortium (Target... 2 | 125
RFA-RM-18-021 2 | 328

IMPC Phenotype

preweaning lethality, complete... 10 | 979
preweaning lethality, incomple... 5 | 499
abnormal bone structure 3 | 187
increased bone mineral content 3 | 108
abnormal coat-hair pigmentatio... 2 | 64
abnormal embryo size 2 | 220
abnormal gait 2 | 69
abnormal retina morphology 2 | 71
cataract 2 | 92
decreased fasted circulating g... 2 | 65
decreased grip strength 2 | 116
embryonic lethality prior to o... 2 | 239
embryonic lethality prior to t... 2 | 278
increased grip strength 2 | 41
increased lean body mass 2 | 172
increased mean corpuscular hem... 2 | 96
increased mean corpuscular vol... 2 | 92
prenatal lethality prior to he... 2 | 87
prolonged QT interval 2 | 38
small superior vagus ganglion 2 | 74
abnormal behavior 1 | 298
abnormal coat- hair morphology 1 | 19
abnormal embryo turning 1 | 31
abnormal iris morphology 1 | 13
abnormal iris pigmentation 1 | 4
abnormal lens morphology 1 | 81
abnormal retinal inner nuclear... 1 | 8
abnormal seminal vesicle morph... 1 | 114
abnormal skin coloration 1 | 25
abnormal vitreous body morphol... 1 | 10
aorta dilation 1 | 3
decreased body length 1 | 101
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating potassiu... 1 | 20
decreased circulating sodium l... 1 | 22
decreased erythrocyte cell num... 1 | 62
decreased heart left ventricle... 1 | 28
decreased lean body mass 1 | 135
decreased red blood cell distr... 1 | 41
decreased total body fat amoun... 1 | 207
embryonic growth retardation 1 | 106
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
increased body length 1 | 32
increased fasted circulating g... 1 | 76
increased hematocrit 1 | 46
increased lymphocyte cell numb... 1 | 32
increased or absent threshold ... 1 | 101
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
persistence of hyaloid vascula... 1 | 33
polycystic kidney 1 | 15
prenatal lethality 1 | 28
prolonged QRS complex duration 1 | 8
prolonged ST segment 1 | 36
sclerocornea 1 | 2
shortened QT interval 1 | 4
small kidney 1 | 16
thrombocytopenia 1 | 56
tremors 1 | 39
vertebral fusion 1 | 23

Disease

Carcinoma 89 | 11,493
ovarian cancer 82 | 8,520
glioblastoma 65 | 5,792
medulloblastoma, large-cell 65 | 6,241
osteosarcoma 57 | 7,950
psoriasis 55 | 6,694
atypical teratoid / rhabdoid tumor 53 | 5,112
lung cancer 52 | 4,740
adult high grade glioma 47 | 3,801
Breast cancer 42 | 3,578
ependymoma 42 | 4,679
non-small cell lung cancer 39 | 2,890
group 3 medulloblastoma 38 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 34 | 2,989
primitive neuroectodermal tumor 31 | 3,035
Cancer 28 | 2,499
invasive ductal carcinoma 28 | 2,951
malignant mesothelioma 28 | 3,232
oligodendroglioma 28 | 2,850
intraductal papillary-mucinous neoplasm (IPMN) 27 | 3,291
subependymal giant cell astrocytoma 26 | 2,287
breast carcinoma 25 | 1,638
colon cancer 25 | 1,478
Kidney cancer 24 | 2,613
lung adenocarcinoma 24 | 2,716
astrocytic glioma 23 | 2,597
intraductal papillary-mucinous adenoma (IPMA) 23 | 2,955
nasopharyngeal carcinoma 22 | 1,058
Pick disease 21 | 1,894
adrenocortical carcinoma 20 | 1,428
lung carcinoma 20 | 2,843
pancreatic cancer 19 | 2,398
ductal carcinoma in situ 18 | 1,745
group 4 medulloblastoma 18 | 1,855
interstitial cystitis 18 | 2,312
Astrocytoma, Pilocytic 16 | 3,081
Endometriosis 14 | 540
Multiple myeloma 14 | 1,332
Atopic dermatitis 13 | 952
tuberculosis 13 | 2,010
Autosomal recessive predisposition 12 | 1,442
pancreatic ductal adenocarcinoma liver metastasis 12 | 1,962
Epilepsy 11 | 792
Neuroblastoma 11 | 80
Rheumatoid arthritis 11 | 1,191
Seizures 11 | 596
dermatomyositis 11 | 966
diabetes mellitus 11 | 1,728
pituitary cancer 11 | 1,972
Cognitive delay 10 | 608
Global developmental delay 10 | 608
Intellectual disability 10 | 1,016
Kaposi's sarcoma 10 | 22
Mental and motor retardation 10 | 608
Metastatic Breast Carcinoma 10 | 21
Metastatic Prostate Carcinoma 10 | 18
Rhabdomyosarcoma 10 | 39
primary pancreatic ductal adenocarcinoma 10 | 1,109
progressive supranuclear palsy 10 | 676
transitional cell carcinoma 10 | 22
ulcerative colitis 10 | 1,819
Acute lymphoid leukemia 9 | 25
Anaplastic large T-cell systemic malignant lymphoma 9 | 10
Burkitt's lymphoma 9 | 15
Carcinoma of breast 9 | 11
Carcinoma of female breast 9 | 20
Diffuse non-Hodgkin's lymphoma, large cell 9 | 12
Follicular non-Hodgkin's lymphoma 9 | 17
Gestational trophoblastic neoplasia 9 | 14
HER2-positive carcinoma of breast 9 | 21
Hodgkin's disease 9 | 18
Hypertensive disorder 9 | 56
Langerhans cell histiocytosis, disseminated 9 | 10
Liposarcoma 9 | 20
Lissencephaly 9 | 69
Malignant tumor of head and/or neck 9 | 15
Malignant tumor of ovary 9 | 25
Malignant tumor of prostate 9 | 26
Malignant tumor of stomach 9 | 12
Malignant tumor of testis 9 | 11
Muscle hypotonia 9 | 571
Mycosis fungoides 9 | 29
Nephroblastoma 9 | 51
Non-Hodgkin's lymphoma 9 | 22
Ocular hypertension 9 | 42
Open-angle glaucoma 9 | 27
Secondary malignant neoplasm of pancreas 9 | 10
fibroadenoma 9 | 559
medulloblastoma 9 | 720
Amyotrophic lateral sclerosis 8 | 451
Bipolar Disorder 8 | 666
Microcephaly 8 | 166
Neurodegenerative disease 8 | 414
Small head 8 | 374
Waldenstrons macroglobulinemia 8 | 765
pediatric high grade glioma 8 | 1,064
spina bifida 8 | 1,074
Low intelligence 7 | 645
Mental deficiency 7 | 645
Poor school performance 7 | 645

Tissue

Endocrine System 134 | 18,159
Female tissues 131 | 17,400
Blood and immune system 130 | 16,909
Male tissues 130 | 17,142
Skin and soft tissues 130 | 17,230
Urinary Tract 130 | 16,678
Digestive Tract 129 | 17,369
Nervous System 129 | 16,725
Respiratory system 127 | 16,393
Liver and Pancreas 126 | 16,750
Cardiovascular System 125 | 15,192

Target Family

Non-IDG 103 | 12,091
Kinase 12 | 634
Enzyme 11 | 4,145
Transcription Factor 7 | 1,400
Nuclear Receptor 1 | 48

GO Component

microtubule cytoskeleton 134 | 134
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Tubulin beta-4A chain TUBB4A Tclin Non-IDG -2.98371 896.1 90
CAP-Gly domain-containing linker protein 1 CLIP1 Tbio Non-IDG -2.54943 343.7 221
MAP7 domain-containing protein 1 MAP7D1 Tdark Non-IDG 0.27 0.84 52
Huntingtin-interacting protein K HYPK Tbio Non-IDG -0.84672 8.89 4
Cytoskeleton-associated protein 2 CKAP2 Tbio Non-IDG -2.30784 205.9 84
GAS2-like protein 3 GAS2L3 Tbio Non-IDG -0.65733 5.79 78
Adenomatous polyposis coli protein 2 APC2 Tbio Non-IDG -1.50271 33.3 93
Echinoderm microtubule-associated protein-like 5 EML5 Tdark Non-IDG -0.47268 3.14 28
Tubulin beta-6 chain TUBB6 Tclin Non-IDG -0.94163 8.01 85
Tubulin alpha-8 chain TUBA8 Tbio Non-IDG -0.87821 7.61 118