Development Level

Tbio 84 | 10,625
Tchem 22 | 1,890
Tdark 21 | 7,003

Collection

Kinase: IDG Consortium (Complete/Control) 2 | 37
Kinase: IDG Consortium (Targets) 2 | 125

IMPC Phenotype

preweaning lethality, complete... 11 | 633
increased mean corpuscular vol... 4 | 91
abnormal bone structure 2 | 131
abnormal cranium morphology 2 | 32
embryonic lethality prior to o... 2 | 148
embryonic lethality prior to t... 2 | 187
increased bone mineral content 2 | 92
increased grip strength 2 | 83
increased mean corpuscular hem... 2 | 93
prenatal lethality prior to he... 2 | 64
abnormal coat- hair morphology 1 | 18
abnormal coat-hair pigmentatio... 1 | 54
abnormal craniofacial morpholo... 1 | 12
abnormal iris morphology 1 | 12
abnormal retina morphology 1 | 100
abnormal retinal pigmentation 1 | 61
abnormal sacral vertebrae morp... 1 | 5
abnormal seminal vesicle morph... 1 | 47
decreased B cell number 1 | 30
decreased body length 1 | 108
decreased bone mineral content 1 | 157
decreased caudal vertebrae num... 1 | 49
decreased circulating potassiu... 1 | 17
decreased eosinophil cell numb... 1 | 41
decreased erythrocyte cell num... 1 | 43
decreased gamma-delta T cell n... 1 | 18
decreased lean body mass 1 | 195
decreased neutrophil cell numb... 1 | 37
decreased pro-B cell number 1 | 2
decreased red blood cell distr... 1 | 11
decreased total body fat amoun... 1 | 186
impaired glucose tolerance 1 | 52
increased circulating bilirubi... 1 | 16
increased exploration in new e... 1 | 56
increased fasted circulating g... 1 | 68
increased hematocrit 1 | 36
increased lean body mass 1 | 107
increased lymphocyte cell numb... 1 | 9
increased mature B cell number 1 | 12
increased pro-B cell number 1 | 1
persistence of hyaloid vascula... 1 | 22
prenatal lethality 1 | 16
preweaning lethality, incomple... 1 | 260
small kidney 1 | 10
small superior vagus ganglion 1 | 20
thrombocytopenia 1 | 46
tremors 1 | 34
vertebral fusion 1 | 23

Disease

ovarian cancer 81 | 8,491
medulloblastoma, large-cell 66 | 6,234
osteosarcoma 60 | 7,933
glioblastoma 59 | 5,572
lung cancer 50 | 4,473
psoriasis 50 | 6,685
atypical teratoid / rhabdoid tumor 43 | 4,369
Breast cancer 34 | 3,098
non-small cell lung cancer 34 | 2,798
intraductal papillary-mucinous carcinoma (IPMC) 33 | 2,988
Cancer 31 | 2,346
invasive ductal carcinoma 31 | 2,950
malignant mesothelioma 30 | 3,163
intraductal papillary-mucinous neoplasm (IPMN) 29 | 3,289
primitive neuroectodermal tumor 28 | 3,031
adult high grade glioma 25 | 2,148
oligodendroglioma 25 | 2,849
pediatric high grade glioma 25 | 2,712
subependymal giant cell astrocytoma 25 | 2,287
ependymoma 24 | 2,514
lung adenocarcinoma 24 | 2,714
intraductal papillary-mucinous adenoma (IPMA) 23 | 2,956
group 3 medulloblastoma 21 | 2,254
sonic hedgehog group medulloblastoma 21 | 1,482
adrenocortical carcinoma 20 | 1,427
breast carcinoma 20 | 1,614
ductal carcinoma in situ 20 | 1,745
nasopharyngeal carcinoma 20 | 1,056
Pick disease 19 | 1,893
colon cancer 19 | 1,475
interstitial cystitis 19 | 2,299
astrocytic glioma 18 | 2,241
Carcinoma 17 | 2,147
medulloblastoma 16 | 1,524
Atopic dermatitis 15 | 944
lung carcinoma 15 | 2,844
pancreatic cancer 15 | 2,300
pilocytic astrocytoma 15 | 3,086
Endometriosis 14 | 535
group 4 medulloblastoma 14 | 1,875
Rheumatoid Arthritis 13 | 1,170
pancreatic ductal adenocarcinoma liver metastasis 13 | 1,795
posterior fossa group A ependymoma 13 | 1,511
Multiple myeloma 12 | 1,327
atypical teratoid/rhabdoid tumor 12 | 1,095
diabetes mellitus 12 | 1,663
posterior fossa group B ependymoma 12 | 1,530
Waldenstrons macroglobulinemia 11 | 764
progressive supranuclear palsy 11 | 674
tuberculosis 11 | 1,563
astrocytoma 10 | 1,493
pituitary cancer 10 | 1,972
Schizophrenia 9 | 503
acute myeloid leukemia 9 | 785
dermatomyositis 9 | 966
tuberculosis and treatment for 6 months 9 | 686
ulcerative colitis 9 | 2,087
primary pancreatic ductal adenocarcinoma 8 | 1,271
spina bifida 8 | 1,064
IGA Glomerulonephritis 7 | 454
Neurodegenerative disease 7 | 383
Vascular disease 7 | 281
active Crohn's disease 7 | 918
cutaneous lupus erythematosus 7 | 1,056
fibroadenoma 7 | 557
Mammary Neoplasms 6 | 410
Microcephaly 6 | 149
Prostatic Neoplasms 6 | 471
Squamous cell carcinoma 6 | 96
cystic fibrosis 6 | 1,670
esophageal adenocarcinoma 6 | 737
Alzheimer's disease 5 | 644
Bipolar Disorder 5 | 266
Intellectual disability 5 | 573
Lung Neoplasms 5 | 171
Neoplasm Metastasis 5 | 138
active ulcerative colitis 5 | 477
inflammatory breast cancer 5 | 404
non primary Sjogren syndrome sicca 5 | 840
non-small cell lung carcinoma 5 | 413
Amyotrophic Lateral Sclerosis 4 | 432
Asthma 4 | 349
Colonic Neoplasms 4 | 126
Colorectal Neoplasms 4 | 217
Kidney Neoplasm 4 | 27
Neuropathy 4 | 210
Parkinson's disease 4 | 364
Retinitis pigmentosa 4 | 156
Stomach Neoplasms 4 | 282
gastric carcinoma 4 | 832
hepatocellular carcinoma 4 | 550
hereditary spastic paraplegia 4 | 313
primary Sjogren syndrome 4 | 788
Arthritis 3 | 248
Down syndrome 3 | 548
Myocardial Ischemia 3 | 169
Peripheral Neuropathy 3 | 303
aldosterone-producing adenoma 3 | 664
chronic rhinosinusitis 3 | 512
juvenile dermatomyositis 3 | 1,189

Tissue

Blood and immune system 127 | 17,994
Cardiovascular System 127 | 17,957
Digestive Tract 127 | 18,472
Endocrine System 127 | 18,511
Female tissues 127 | 18,646
Liver and Pancreas 127 | 18,135
Male tissues 127 | 17,968
Nervous System 127 | 18,560
Skin and soft tissues 127 | 18,114
Urinary Tract 127 | 18,443
Respiratory system 125 | 17,483

Target Family

Non-IDG 90 | 11,969
Enzyme 15 | 4,146
Kinase 13 | 634
Transcription Factor 8 | 1,400
Nuclear Receptor 1 | 48

GO Component

microtubule cytoskeleton 127 | 127
nucleus 5,106 | 5,106
cytoplasm 4,984 | 4,984
plasma membrane 4,118 | 4,118
integral component of membrane 3,679 | 3,679
cytosol 3,264 | 3,264
extracellular exosome 2,757 | 2,757
nucleoplasm 2,716 | 2,716
membrane 1,906 | 1,906
extracellular region 1,493 | 1,493
integral component of plasma m... 1,406 | 1,406
extracellular space 1,304 | 1,304
mitochondrion 1,231 | 1,231
Golgi apparatus 864 | 864
endoplasmic reticulum 859 | 859
endoplasmic reticulum membrane 848 | 848
nucleolus 815 | 815
Golgi membrane 659 | 659
perinuclear region of cytoplas... 611 | 611
cell surface 594 | 594
intracellular 548 | 548
intracellular membrane-bounded... 536 | 536
cell junction 451 | 451
mitochondrial inner membrane 425 | 425
centrosome 409 | 409
focal adhesion 383 | 383
protein complex 355 | 355
cytoskeleton 343 | 343
dendrite 329 | 329
mitochondrial matrix 322 | 322
cell-cell adherens junction 307 | 307
neuronal cell body 303 | 303
microtubule 294 | 294
lysosomal membrane 278 | 278
apical plasma membrane 277 | 277
proteinaceous extracellular ma... 244 | 244
neuron projection 229 | 229
nuclear membrane 218 | 218
early endosome 217 | 217
axon 214 | 214
lysosome 210 | 210
endosome 208 | 208
actin cytoskeleton 205 | 205
external side of plasma membra... 205 | 205
postsynaptic membrane 204 | 204
extracellular matrix 198 | 198
nuclear speck 197 | 197
membrane raft 196 | 196
endoplasmic reticulum lumen 192 | 192
transcription factor complex 184 | 184
endosome membrane 182 | 182
early endosome membrane 180 | 180
basolateral plasma membrane 174 | 174
nuclear chromatin 169 | 169
synapse 166 | 166
cell-cell junction 161 | 161
nuclear envelope 156 | 156
lamellipodium 153 | 153
mitochondrial outer membrane 148 | 148
blood microparticle 147 | 147
myelin sheath 144 | 144
postsynaptic density 144 | 144
cytoplasmic vesicle 143 | 143
microtubule organizing center 137 | 137
cytoplasmic, membrane-bounded ... 132 | 132
ER to Golgi transport vesicle ... 131 | 131
receptor complex 127 | 127
phagocytic vesicle membrane 126 | 126
cytoplasmic vesicle membrane 125 | 125
midbody 125 | 125
trans-Golgi network 124 | 124
cell cortex 119 | 119
cilium 118 | 118
late endosome 116 | 116
spindle 116 | 116
intracellular ribonucleoprotei... 114 | 114
vesicle 112 | 112
Z disc 110 | 110
bicellular tight junction 110 | 110
anchored component of membrane 109 | 109
growth cone 109 | 109
integral component of lumenal ... 108 | 108
late endosome membrane 107 | 107
endomembrane system 106 | 106
centriole 105 | 105
recycling endosome 104 | 104
spindle pole 104 | 104
perikaryon 103 | 103
integral component of endoplas... 101 | 101
intermediate filament 101 | 101
melanosome 101 | 101
chromosome 100 | 100
dendritic spine 99 | 99
ubiquitin ligase complex 99 | 99
peroxisome 98 | 98
nuclear matrix 97 | 97
PML body 94 | 94
Golgi lumen 93 | 93
keratin filament 93 | 93
trans-Golgi network membrane 92 | 92

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Centrosomal protein of 131 kDa CEP131 Tbio Non-IDG -1.75708 61.0 81
Cyclin-dependent kinase 16 CDK16 Tchem Kinase -1.43415 32.3 122
Protein kinase C iota type PRKCI Tchem Kinase -1.69816 51.8 122
Protein timeless homolog TIMELESS Tbio Non-IDG -2.74942 550.7 135
Microtubule-associated serine/threonine-protein kinase 2 MAST2 Tchem Kinase -1.28571 18.6 69
Protein regulator of cytokinesis 1 PRC1 Tbio Non-IDG -0.85707 4.86 161
Spermatid perinuclear RNA-binding protein STRBP Tdark Non-IDG -1.83687 66.9 35
Microprocessor complex subunit DGCR8 DGCR8 Tbio Non-IDG -2.44183 254.1 201
Spectrin alpha chain, non-erythrocytic 1 SPTAN1 Tbio Non-IDG -2.41058 258.0 266
Katanin p80 WD40 repeat-containing subunit B1 KATNB1 Tbio Non-IDG -0.99539 8.19 132