Development Level

Tbio 191 | 10,625
Tdark 54 | 7,003
Tchem 38 | 1,890
Tclin 11 | 602

Collection

Eligible Kinase Proteins 2 | 134

IMPC Term

preweaning lethality, complete... 17 | 633
abnormal behavior 7 | 226
decreased body weight 7 | 174
decreased bone mineral content 6 | 157
hyperactivity 6 | 108
decreased lean body mass 5 | 195
decreased total body fat amoun... 5 | 186
increased mean corpuscular hem... 5 | 93
abnormal bone structure 4 | 131
decreased body length 4 | 108
increased circulating alkaline... 4 | 119
increased lean body mass 4 | 107
preweaning lethality, incomple... 4 | 260
abnormal embryo size 3 | 112
abnormal retina morphology 3 | 100
abnormal sleep behavior 3 | 63
decreased caudal vertebrae num... 3 | 49
decreased circulating glucose ... 3 | 121
decreased circulating serum al... 3 | 79
embryonic lethality prior to t... 3 | 187
increased fasted circulating g... 3 | 68
increased mean corpuscular vol... 3 | 91
abnormal behavioral response t... 2 | 52
abnormal bone mineralization 2 | 55
abnormal cranium morphology 2 | 32
abnormal head morphology 2 | 10
abnormal tail movements 2 | 12
absent pinna reflex 2 | 21
decreased bone mineral density 2 | 126
decreased circulating LDL chol... 2 | 37
decreased circulating aspartat... 2 | 27
decreased circulating free fat... 2 | 39
decreased circulating total pr... 2 | 41
decreased eosinophil cell numb... 2 | 41
decreased mean corpuscular vol... 2 | 50
hypoactivity 2 | 89
increased circulating chloride... 2 | 43
increased circulating sodium l... 2 | 71
increased heart weight 2 | 37
increased or absent threshold ... 2 | 128
increased sacral vertebrae num... 2 | 62
limb grasping 2 | 35
male infertility 2 | 62
persistence of hyaloid vascula... 2 | 22
prenatal lethality prior to he... 2 | 64
abnormal embryo turning 1 | 15
abnormal eye morphology 1 | 38
abnormal facial morphology 1 | 9
abnormal gait 1 | 51
abnormal head shape 1 | 4
abnormal kidney morphology 1 | 30
abnormal lens morphology 1 | 73
abnormal limb bud morphology 1 | 15
abnormal lung morphology 1 | 15
abnormal neural tube closure 1 | 37
abnormal neural tube morpholog... 1 | 8
abnormal optic disc morphology 1 | 10
abnormal retinal blood vessel ... 1 | 18
abnormal vertebrae morphology 1 | 14
abnormal vocalization 1 | 21
convulsive seizures 1 | 11
decreased CD4-positive, CD25-p... 1 | 24
decreased anxiety-related resp... 1 | 12
decreased basophil cell number 1 | 11
decreased circulating calcium ... 1 | 33
decreased circulating phosphat... 1 | 15
decreased circulating potassiu... 1 | 17
decreased circulating sodium l... 1 | 18
decreased circulating triglyce... 1 | 83
decreased exploration in new e... 1 | 9
decreased grip strength 1 | 123
decreased hemoglobin content 1 | 53
decreased lumbar vertebrae num... 1 | 62
decreased red blood cell distr... 1 | 11
decreased total retina thickne... 1 | 20
embryonic growth retardation 1 | 28
enlarged lymph nodes 1 | 27
hemorrhage 1 | 12
increased body length 1 | 20
increased bone mineral density 1 | 52
increased circulating HDL chol... 1 | 63
increased circulating aspartat... 1 | 17
increased circulating choleste... 1 | 53
increased circulating creatini... 1 | 29
increased circulating glucose ... 1 | 16
increased circulating magnesiu... 1 | 10
increased circulating triglyce... 1 | 24
increased erythrocyte cell num... 1 | 26
increased grip strength 1 | 83
increased hemoglobin content 1 | 45
increased mean corpuscular hem... 1 | 25
increased startle reflex 1 | 38
increased total body fat amoun... 1 | 57
polycystic kidney 1 | 9
prenatal lethality 1 | 16
short tibia 1 | 82
straub tail 1 | 26
thrombocytopenia 1 | 46
thrombocytosis 1 | 23
vertebral fusion 1 | 23

Disease

ovarian cancer 144 | 8,484
osteosarcoma 131 | 7,933
medulloblastoma, large-cell 128 | 6,234
glioblastoma 115 | 5,572
psoriasis 110 | 6,685
lung cancer 97 | 4,466
atypical teratoid / rhabdoid tumor 88 | 4,369
primitive neuroectodermal tumor 68 | 3,031
oligodendroglioma 67 | 2,849
pediatric high grade glioma 66 | 2,712
pilocytic astrocytoma 63 | 3,086
Carcinoma 62 | 2,147
malignant mesothelioma 61 | 3,162
Breast cancer 60 | 3,094
ependymoma 60 | 2,514
non-small cell lung cancer 57 | 2,798
intraductal papillary-mucinous neoplasm (IPMN) 55 | 3,289
group 3 medulloblastoma 53 | 2,254
intraductal papillary-mucinous carcinoma (IPMC) 53 | 2,988
invasive ductal carcinoma 51 | 2,950
posterior fossa group B ependymoma 48 | 1,530
astrocytic glioma 47 | 2,241
lung carcinoma 47 | 2,844
Pick disease 46 | 1,893
intraductal papillary-mucinous adenoma (IPMA) 44 | 2,956
lung adenocarcinoma 42 | 2,713
subependymal giant cell astrocytoma 42 | 2,287
colon cancer 41 | 1,475
pancreatic cancer 38 | 2,300
ductal carcinoma in situ 37 | 1,745
nasopharyngeal carcinoma 36 | 1,056
group 4 medulloblastoma 35 | 1,875
Cancer 34 | 2,346
adrenocortical carcinoma 34 | 1,427
adult high grade glioma 31 | 2,148
breast carcinoma 31 | 1,614
medulloblastoma 31 | 1,524
pituitary cancer 31 | 1,972
sonic hedgehog group medulloblastoma 31 | 1,482
astrocytoma 29 | 1,493
interstitial cystitis 26 | 2,299
atypical teratoid/rhabdoid tumor 24 | 1,095
chronic rhinosinusitis 24 | 512
juvenile dermatomyositis 24 | 1,189
posterior fossa group A ependymoma 24 | 1,511
Multiple myeloma 23 | 1,327
acute quadriplegic myopathy 22 | 1,157
progressive supranuclear palsy 22 | 674
primary pancreatic ductal adenocarcinoma 20 | 1,271
ulcerative colitis 20 | 2,087
pancreatic ductal adenocarcinoma liver metastasis 19 | 1,795
Atopic dermatitis 18 | 944
Endometriosis 18 | 535
diabetes mellitus 18 | 1,663
spina bifida 18 | 1,064
tuberculosis 18 | 1,557
Intellectual disability 17 | 573
dermatomyositis 17 | 933
Lissencephaly 16 | 61
Microcephaly 16 | 149
Neurodegenerative disease 16 | 383
non-small cell lung carcinoma 16 | 413
Amyotrophic Lateral Sclerosis 15 | 431
Alzheimer's disease 14 | 644
Primary ciliary dyskinesia 14 | 73
acute myeloid leukemia 14 | 780
hereditary spastic paraplegia 14 | 313
tuberculosis and treatment for 6 months 14 | 686
Rheumatoid Arthritis 13 | 1,160
Waldenstrons macroglobulinemia 13 | 765
cystic fibrosis 13 | 1,665
Down syndrome 12 | 548
IGA Glomerulonephritis 12 | 454
Neuroblastoma 12 | 78
fibroadenoma 12 | 557
hepatocellular carcinoma 12 | 532
inflammatory breast cancer 12 | 404
Neuropathy 11 | 210
Situs Inversus 11 | 48
cutaneous lupus erythematosus 11 | 1,056
gastric carcinoma 11 | 832
non primary Sjogren syndrome sicca 11 | 840
autosomal dominant Emery-Dreifuss muscular dystrophy 10 | 499
gastric cancer 10 | 430
primary Sjogren syndrome 10 | 789
Duchenne muscular dystrophy 9 | 602
HER2-positive carcinoma of breast 9 | 10
Kaposi's sarcoma 9 | 20
Kidney cancer 9 | 118
Liposarcoma 9 | 20
Malignant tumor of head and/or neck 9 | 15
Malignant tumor of ovary 9 | 25
Mammary Neoplasms 9 | 410
Nephroblastoma 9 | 45
Open-angle glaucoma 9 | 26
Rhabdomyosarcoma 9 | 29
Secondary malignant neoplasm of pancreas 9 | 10
Transitional cell carcinoma 9 | 18
cystic fibrosis and chronic rhinosinusitis 9 | 213
esophageal adenocarcinoma 9 | 737

Tissue

Blood and immune system 291 | 17,995
Female tissues 291 | 18,647
Male tissues 291 | 17,969
Nervous System 291 | 18,561
Cardiovascular System 290 | 17,958
Digestive Tract 290 | 18,473
Endocrine System 290 | 18,512
Liver and Pancreas 289 | 18,136
Urinary Tract 289 | 18,444
Skin and soft tissues 287 | 18,115
Respiratory system 285 | 17,484

Target Family

Non-IDG 251 | 11,971
Enzyme 30 | 4,146
Kinase 7 | 634
Epigenetic 3 | 242
Transporter 2 | 473
Transcription Factor 1 | 1,400

GO Component

microtubule 294 | 294
nucleus 5,107 | 5,107
cytoplasm 4,985 | 4,985
plasma membrane 4,118 | 4,118
integral component of membrane 3,679 | 3,679
cytosol 3,265 | 3,265
extracellular exosome 2,758 | 2,758
nucleoplasm 2,717 | 2,717
membrane 1,906 | 1,906
extracellular region 1,493 | 1,493
integral component of plasma m... 1,406 | 1,406
extracellular space 1,304 | 1,304
mitochondrion 1,231 | 1,231
Golgi apparatus 864 | 864
endoplasmic reticulum 859 | 859
endoplasmic reticulum membrane 848 | 848
nucleolus 815 | 815
Golgi membrane 659 | 659
perinuclear region of cytoplas... 611 | 611
cell surface 594 | 594
intracellular 548 | 548
intracellular membrane-bounded... 537 | 537
cell junction 451 | 451
mitochondrial inner membrane 425 | 425
centrosome 409 | 409
focal adhesion 383 | 383
protein complex 355 | 355
cytoskeleton 343 | 343
dendrite 329 | 329
mitochondrial matrix 322 | 322
cell-cell adherens junction 307 | 307
neuronal cell body 303 | 303
lysosomal membrane 278 | 278
apical plasma membrane 277 | 277
proteinaceous extracellular ma... 244 | 244
neuron projection 229 | 229
nuclear membrane 218 | 218
early endosome 217 | 217
axon 214 | 214
lysosome 210 | 210
endosome 208 | 208
actin cytoskeleton 205 | 205
external side of plasma membra... 205 | 205
postsynaptic membrane 204 | 204
extracellular matrix 198 | 198
nuclear speck 197 | 197
membrane raft 196 | 196
endoplasmic reticulum lumen 192 | 192
transcription factor complex 184 | 184
endosome membrane 182 | 182
early endosome membrane 180 | 180
basolateral plasma membrane 174 | 174
nuclear chromatin 169 | 169
synapse 166 | 166
cell-cell junction 161 | 161
nuclear envelope 156 | 156
lamellipodium 153 | 153
mitochondrial outer membrane 148 | 148
blood microparticle 147 | 147
myelin sheath 144 | 144
postsynaptic density 144 | 144
cytoplasmic vesicle 143 | 143
microtubule organizing center 137 | 137
cytoplasmic, membrane-bounded ... 132 | 132
ER to Golgi transport vesicle ... 131 | 131
microtubule cytoskeleton 127 | 127
receptor complex 127 | 127
phagocytic vesicle membrane 126 | 126
cytoplasmic vesicle membrane 125 | 125
midbody 125 | 125
trans-Golgi network 124 | 124
cell cortex 119 | 119
cilium 118 | 118
late endosome 116 | 116
spindle 116 | 116
intracellular ribonucleoprotei... 114 | 114
vesicle 112 | 112
Z disc 110 | 110
bicellular tight junction 110 | 110
anchored component of membrane 109 | 109
growth cone 109 | 109
integral component of lumenal ... 108 | 108
late endosome membrane 107 | 107
endomembrane system 106 | 106
centriole 105 | 105
recycling endosome 104 | 104
spindle pole 104 | 104
perikaryon 103 | 103
integral component of endoplas... 101 | 101
intermediate filament 101 | 101
melanosome 101 | 101
chromosome 100 | 100
dendritic spine 99 | 99
ubiquitin ligase complex 99 | 99
peroxisome 98 | 98
nuclear matrix 97 | 97
PML body 94 | 94
Golgi lumen 93 | 93
keratin filament 93 | 93
trans-Golgi network membrane 92 | 92

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Kinesin-like protein KIF1C KIF1C Tbio Non-IDG -1.21884 20.0 95
Emerin EMD Tbio Non-IDG -2.77469 617.6 238
Dynein light chain 1, cytoplasmic DYNLL1 Tbio Non-IDG -2.65303 525.6 142
Golgin subfamily A member 2 GOLGA2 Tbio Non-IDG -1.94177 80.5 168
Kinesin-like protein KIFC3 KIFC3 Tchem Non-IDG -1.08696 12.5 48
Dynein heavy chain 14, axonemal DNAH14 Tdark Non-IDG -0.16914 1.36 38
Tubulin beta-2A chain TUBB2A Tclin Non-IDG -1.58651 36.1 215
Retinitis pigmentosa 1-like 1 protein RP1L1 Tbio Non-IDG -1.19453 19.3 0
Kinesin-like protein KIF3B KIF3B Tbio Non-IDG -1.33400 20.0 84
WD repeat-containing protein 81 WDR81 Tdark Non-IDG -1.18646 17.0 6