Development Level

Tbio 210 | 11,651
Tdark 50 | 6,593
Tchem 26 | 1,388
Tclin 12 | 612

Collection

Kinase: IDG Consortium (Target... 2 | 125

IMPC Phenotype

preweaning lethality, complete... 24 | 979
preweaning lethality, incomple... 11 | 499
abnormal behavior 7 | 298
abnormal embryo size 7 | 220
decreased body weight 7 | 161
decreased total body fat amoun... 7 | 207
abnormal bone structure 6 | 187
decreased body length 6 | 101
decreased bone mineral density 6 | 126
embryonic lethality prior to t... 6 | 278
hypoactivity 6 | 132
decreased bone mineral content 5 | 151
decreased circulating glucose ... 5 | 126
decreased lean body mass 5 | 135
hyperactivity 5 | 148
abnormal sleep behavior 4 | 70
decreased fasted circulating g... 4 | 65
embryonic growth retardation 4 | 106
prenatal lethality prior to he... 4 | 87
abnormal lung morphology 3 | 26
decreased caudal vertebrae num... 3 | 53
decreased circulating serum al... 3 | 82
decreased grip strength 3 | 116
embryonic lethality prior to o... 3 | 239
increased body length 3 | 32
increased circulating alkaline... 3 | 122
increased fasted circulating g... 3 | 76
increased mean corpuscular hem... 3 | 96
increased mean corpuscular vol... 3 | 92
increased total body fat amoun... 3 | 134
male infertility 3 | 123
short tibia 3 | 97
abnormal behavioral response t... 2 | 66
abnormal bone mineralization 2 | 38
abnormal cranium morphology 2 | 36
abnormal embryo turning 2 | 31
abnormal gait 2 | 69
abnormal head morphology 2 | 10
abnormal seminal vesicle morph... 2 | 114
abnormal tail morphology 2 | 25
abnormal tail movements 2 | 12
absent pinna reflex 2 | 23
cataract 2 | 92
cyanosis 2 | 7
decreased circulating LDL chol... 2 | 38
decreased circulating alanine ... 2 | 47
decreased circulating choleste... 2 | 93
decreased circulating free fat... 2 | 31
decreased circulating total pr... 2 | 49
decreased mean corpuscular vol... 2 | 79
decreased red blood cell distr... 2 | 41
edema 2 | 59
enlarged lymph nodes 2 | 37
hemorrhage 2 | 23
increased bone mineral content 2 | 108
increased circulating chloride... 2 | 41
increased circulating sodium l... 2 | 71
increased heart weight 2 | 62
increased lean body mass 2 | 172
increased startle reflex 2 | 112
limb grasping 2 | 41
long tibia 2 | 25
polycystic kidney 2 | 15
thrombocytopenia 2 | 56
abnormal coat- hair morphology 1 | 19
abnormal heart looping 1 | 5
abnormal joint morphology 1 | 23
abnormal lens morphology 1 | 81
abnormal neural tube closure 1 | 46
abnormal neural tube morpholog... 1 | 12
abnormal pericardium morpholog... 1 | 26
abnormal spleen morphology 1 | 55
abnormal testis morphology 1 | 43
abnormal vertebrae morphology 1 | 18
abnormal vitelline vasculature... 1 | 6
abnormal vitreous body morphol... 1 | 10
abnormal vocalization 1 | 21
convulsive seizures 1 | 13
decreased circulating calcium ... 1 | 36
decreased circulating phosphat... 1 | 27
decreased circulating potassiu... 1 | 20
decreased circulating sodium l... 1 | 22
decreased circulating triglyce... 1 | 79
decreased fluid intake 1 | 3
enlarged epididymis 1 | 31
enlarged spleen 1 | 41
impaired pupillary reflex 1 | 26
increased bone mineral density 1 | 72
increased circulating creatini... 1 | 38
increased circulating glucose ... 1 | 24
increased circulating magnesiu... 1 | 10
increased circulating triglyce... 1 | 42
increased leukocyte cell numbe... 1 | 47
microphthalmia 1 | 26
persistence of hyaloid vascula... 1 | 33
prenatal lethality 1 | 28
scaly skin 1 | 4
thrombocytosis 1 | 27
tremors 1 | 39
vertebral fusion 1 | 23

Disease

Carcinoma 225 | 11,493
ovarian cancer 146 | 8,520
osteosarcoma 132 | 7,950
medulloblastoma, large-cell 129 | 6,241
ependymoma 120 | 4,679
glioblastoma 119 | 5,792
psoriasis 113 | 6,694
atypical teratoid / rhabdoid tumor 108 | 5,112
lung cancer 106 | 4,740
group 3 medulloblastoma 103 | 4,104
Breast cancer 79 | 3,578
adult high grade glioma 77 | 3,801
Kidney cancer 73 | 2,613
primitive neuroectodermal tumor 68 | 3,035
oligodendroglioma 67 | 2,850
Astrocytoma, Pilocytic 63 | 3,081
malignant mesothelioma 63 | 3,232
non-small cell lung cancer 60 | 2,890
intraductal papillary-mucinous neoplasm (IPMN) 58 | 3,291
astrocytic glioma 57 | 2,597
intraductal papillary-mucinous carcinoma (IPMC) 55 | 2,989
invasive ductal carcinoma 51 | 2,951
Pick disease 49 | 1,894
lung carcinoma 48 | 2,843
intraductal papillary-mucinous adenoma (IPMA) 45 | 2,955
lung adenocarcinoma 44 | 2,716
pancreatic cancer 44 | 2,398
subependymal giant cell astrocytoma 44 | 2,287
colon cancer 41 | 1,478
nasopharyngeal carcinoma 38 | 1,058
ductal carcinoma in situ 36 | 1,745
Cancer 34 | 2,499
adrenocortical carcinoma 34 | 1,428
group 4 medulloblastoma 34 | 1,855
pituitary cancer 32 | 1,972
breast carcinoma 30 | 1,638
Intellectual disability 27 | 1,016
chronic rhinosinusitis 27 | 512
interstitial cystitis 27 | 2,312
Autosomal recessive predisposition 26 | 1,442
Liver cancer 25 | 604
Multiple myeloma 23 | 1,332
juvenile dermatomyositis 23 | 1,187
pancreatic ductal adenocarcinoma liver metastasis 22 | 1,962
pediatric high grade glioma 22 | 1,064
progressive supranuclear palsy 22 | 676
astrocytoma 21 | 1,146
tuberculosis 21 | 2,010
Atopic dermatitis 20 | 952
Cognitive delay 20 | 608
Global developmental delay 20 | 608
Melanoma 20 | 711
Mental and motor retardation 20 | 608
acute quadriplegic myopathy 20 | 1,158
Endometrial cancer 19 | 311
Schizophrenia 19 | 1,160
diabetes mellitus 19 | 1,728
spina bifida 19 | 1,074
Endometriosis 18 | 540
Microcephaly 18 | 166
Seizures 18 | 596
ulcerative colitis 18 | 1,819
Alzheimer's disease 17 | 658
Lissencephaly 17 | 69
Neurodegenerative disease 17 | 414
Primary ciliary dyskinesia 17 | 76
Small head 17 | 374
Amyotrophic lateral sclerosis 16 | 451
Dull intelligence 16 | 645
Epilepsy 16 | 792
Low intelligence 16 | 645
Mental Retardation 16 | 645
Mental deficiency 16 | 645
Poor school performance 16 | 645
dermatomyositis 16 | 966
acute myeloid leukemia 15 | 783
cystic fibrosis 15 | 1,696
primary pancreatic ductal adenocarcinoma 15 | 1,109
Skin cancer 14 | 469
hereditary spastic paraplegia 14 | 318
non-small cell lung carcinoma 14 | 317
Muscle hypotonia 13 | 571
Waldenstrons macroglobulinemia 13 | 765
hepatocellular carcinoma 13 | 547
non primary Sjogren syndrome sicca 13 | 891
Anteverted nostril 12 | 191
Neuroblastoma 12 | 80
Neuropathy 12 | 261
Rheumatoid arthritis 12 | 1,191
Short stature 12 | 531
esophageal adenocarcinoma 12 | 737
fibroadenoma 12 | 559
Bipolar Disorder 11 | 666
cutaneous lupus erythematosus 11 | 1,057
cystic fibrosis and chronic rhinosinusitis 11 | 214
posterior fossa group B ependymoma 11 | 416
tuberculosis and treatment for 6 months 11 | 409
gastric cancer 10 | 459
gastric carcinoma 10 | 807
primary Sjogren syndrome 10 | 735

Tissue

Endocrine System 295 | 18,159
Female tissues 289 | 17,400
Skin and soft tissues 288 | 17,230
Digestive Tract 286 | 17,369
Male tissues 285 | 17,142
Respiratory system 284 | 16,393
Nervous System 283 | 16,725
Urinary Tract 283 | 16,678
Blood and immune system 281 | 16,909
Liver and Pancreas 279 | 16,750
Cardiovascular System 262 | 15,192

Target Family

Non-IDG 252 | 12,091
Enzyme 31 | 4,145
Kinase 9 | 634
Epigenetic 3 | 242
Transporter 2 | 473
Transcription Factor 1 | 1,400

GO Component

microtubule 298 | 298
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Echinoderm microtubule-associated protein-like 5 EML5 Tdark Non-IDG -0.47268 3.14 28
T-complex protein 1 subunit zeta CCT6A Tbio Non-IDG -1.39880 26.2 90
Serine/threonine-protein kinase DCLK2 DCLK2 Tchem Kinase -0.89222 8.01 148
Dynein heavy chain 6, axonemal DNAH6 Tbio Non-IDG -0.53057 4.17 18
Fidgetin FIGN Tbio Enzyme -1.34015 21.2 103
Oxygen-regulated protein 1 RP1 Tbio Non-IDG 0.30 0.88 40
Tubulin epsilon chain TUBE1 Tbio Non-IDG -2.57316 368.1 99
Probable tubulin polyglutamylase TTLL1 TTLL1 Tdark Enzyme -0.79170 5.84 34
Cytoplasmic dynein 1 light intermediate chain 1 DYNC1LI1 Tbio Non-IDG -1.67860 45.9 100
Syntabulin SYBU Tbio Non-IDG -0.98265 12.1 14