Development Level

Tbio 9 | 11,445
Tdark 1 | 6,588

IMPC Phenotype

decreased body length 2 | 101
abnormal cranium morphology 1 | 36
abnormal incisor morphology 1 | 4
abnormal radius morphology 1 | 8
abnormal snout morphology 1 | 23
abnormal tooth morphology 1 | 24
abnormal ulna morphology 1 | 8
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating alanine ... 1 | 47
decreased circulating aspartat... 1 | 34
decreased circulating choleste... 1 | 93
decreased circulating iron lev... 1 | 32
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased total body fat amoun... 1 | 207
increased blood urea nitrogen ... 1 | 48
increased hemoglobin content 1 | 45
increased leukocyte cell numbe... 1 | 47
preweaning lethality, incomple... 1 | 499
short tibia 1 | 97

Disease

Carcinoma 7 | 11,493
psoriasis 7 | 6,694
pancreatic cancer 6 | 2,398
Breast cancer 5 | 3,578
ependymoma 5 | 4,679
invasive ductal carcinoma 5 | 2,951
malignant mesothelioma 5 | 3,232
ovarian cancer 5 | 8,520
pituitary cancer 5 | 1,972
primary pancreatic ductal adenocarcinoma 5 | 1,109
atypical teratoid / rhabdoid tumor 4 | 5,112
group 3 medulloblastoma 4 | 4,104
lung carcinoma 4 | 2,843
medulloblastoma, large-cell 4 | 6,241
Atopic dermatitis 3 | 952
Congenital pectus carinatum 3 | 52
Kidney cancer 3 | 2,613
Liver Cirrhosis, Experimental 3 | 769
Weill-Marchesani syndrome 3 | 14
adult high grade glioma 3 | 3,801
cutaneous lupus erythematosus 3 | 1,057
ductal carcinoma in situ 3 | 1,745
glioblastoma 3 | 5,792
interstitial cystitis 3 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
lung cancer 3 | 4,740
Abnormality of the iris 2 | 14
Acquired metabolic disease 2 | 336
Adducted thumb 2 | 22
Aortic Aneurysm, Thoracic 2 | 8
Aortic Valve Insufficiency 2 | 40
Aortic aneurysm 2 | 38
Aortic aneurysm, familial thoracic 3 2 | 13
Aortic root dilatation 2 | 11
Arachnodactyly 2 | 49
Ascending aortic dissection 2 | 13
Astrocytoma, Pilocytic 2 | 3,081
Brachycephaly 2 | 88
Brachydactyly 2 | 156
Broad cranium shape 2 | 88
Byzanthine arch palate 2 | 194
Cardiomegaly 2 | 116
Chest Pain 2 | 38
Chronic obstructive pulmonary disease 2 | 184
Coronary artery disease 2 | 268
Crumpled ear 2 | 3
Cutis marmorata 2 | 32
Cystic medial necrosis of aorta 2 | 13
Descending aortic dissection 2 | 13
Duchenne muscular dystrophy 2 | 601
Dyspnea on exertion 2 | 24
Dyspnea, Paroxysmal 2 | 13
Ectopia Lentis 2 | 17
Endometriosis 2 | 540
Familial thoracic aortic aneurysm and aortic dissection 2 | 13
Glaucoma 2 | 239
Hypertensive disease 2 | 292
Impaired left ventricular function 2 | 16
Increase in blood pressure 2 | 119
Joint stiffness 2 | 84
Large intestine cancer 2 | 126
Left-Sided Heart Failure 2 | 16
Loeys-Dietz Aortic Aneurysm Syndrome 2 | 13
Long narrow head 2 | 75
Marfan Syndrome 2 | 15
Marfanoid body habitus 2 | 11
Melanoma 2 | 711
Mitral Valve Prolapse Syndrome 2 | 39
Mitral regurgitation, mild 2 | 32
Mitral valve insufficiency 2 | 49
Motor delay 2 | 147
Myopia 2 | 176
Narrow cranium shape 2 | 75
Narrow head shape 2 | 75
Narrow skull shape 2 | 75
No development of motor milestones 2 | 147
Patent ductus arteriosus 2 | 90
Pectus excavatum 2 | 100
Skin cancer 2 | 469
Thoracic aortic aneurysm 2 | 15
Tracheal stenosis 2 | 23
Turridolichocephaly 2 | 75
Ventricular Septal Defects 2 | 119
Wide skull shape 2 | 88
adrenocortical carcinoma 2 | 1,428
breast carcinoma 2 | 1,638
colon cancer 2 | 1,478
cystic fibrosis 2 | 1,696
diabetes mellitus 2 | 1,728
fascioscapulohumeral muscular dystrophy 2 | 100
fibroadenoma 2 | 559
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
juvenile dermatomyositis 2 | 1,187
limb girdle muscular dystrophy 2A 2 | 213
lung adenocarcinoma 2 | 2,716
non-small cell lung cancer 2 | 2,890
osteosarcoma 2 | 7,950
tuberculosis 2 | 2,010
Decreased muscle mass 1 | 28
Stretched skin 1 | 10

Tissue

Blood and immune system 10 | 16,909
Cardiovascular System 10 | 15,192
Digestive Tract 10 | 17,369
Endocrine System 10 | 18,159
Female tissues 10 | 17,400
Liver and Pancreas 10 | 16,750
Male tissues 10 | 17,142
Nervous System 10 | 16,725
Respiratory system 10 | 16,393
Skin and soft tissues 10 | 17,230
Urinary Tract 10 | 16,678

Target Family

Non-IDG 9 | 12,091
Enzyme 1 | 4,145

GO Component

microfibril 10 | 10
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Latent-transforming growth factor beta-binding protein 1 LTBP1 Tbio Non-IDG -1.97590 101.5 128
ADAMTS-like protein 5 ADAMTSL5 Tbio Non-IDG -0.68946 5.88 0
Fibrillin-1 FBN1 Tbio Non-IDG -3.08679 1236.3 325
Fibrillin-2 FBN2 Tbio Non-IDG -2.46578 287.6 123
A disintegrin and metalloproteinase with thrombospondin motifs 10 ADAMTS10 Tbio Enzyme -1.35665 21.7 120
Microfibrillar-associated protein 2 MFAP2 Tbio Non-IDG -1.84472 72.8 129
Thrombospondin type-1 domain-containing protein 4 THSD4 Tdark Non-IDG -0.62904 3.69 5
Microfibrillar-associated protein 5 MFAP5 Tbio Non-IDG -1.48577 34.1 149
Microfibril-associated glycoprotein 4 MFAP4 Tbio Non-IDG -1.36058 24.3 157
Microfibrillar-associated protein 1 MFAP1 Tbio Non-IDG -0.44863 3.83 105