Development Level

Tbio 76 | 11,445
Tchem 19 | 1,598
Tclin 5 | 613
Tdark 1 | 6,588

Collection

GPCR: IDG Consortium (Targets) 1 | 126

IMPC Phenotype

preweaning lethality, complete... 11 | 979
embryonic lethality prior to t... 7 | 278
embryonic lethality prior to o... 6 | 239
preweaning lethality, incomple... 4 | 499
abnormal behavior 3 | 298
abnormal coat-hair pigmentatio... 3 | 64
abnormal retina morphology 3 | 71
abnormal sleep behavior 3 | 70
decreased mean corpuscular hem... 3 | 50
decreased total body fat amoun... 3 | 207
decreased vertical activity 3 | 208
increased circulating sodium l... 3 | 71
abnormal seminal vesicle morph... 2 | 114
abnormal skin morphology 2 | 50
decreased body weight 2 | 161
decreased hemoglobin content 2 | 68
hyperactivity 2 | 148
increased circulating alkaline... 2 | 122
increased grip strength 2 | 41
increased lean body mass 2 | 172
increased startle reflex 2 | 112
increased total body fat amoun... 2 | 134
short tibia 2 | 97
abnormal behavioral response t... 1 | 66
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal eye size 1 | 7
abnormal iris transilluminatio... 1 | 2
abnormal kidney morphology 1 | 65
abnormal lens morphology 1 | 81
abnormal locomotor activation 1 | 16
abnormal motor capabilities-co... 1 | 5
abnormal snout morphology 1 | 23
abnormal spleen morphology 1 | 55
abnormal testis morphology 1 | 43
abnormal vibrissa morphology 1 | 25
absent pinna reflex 1 | 23
cardiovascular system phenotyp... 1 | 36
cataract 1 | 92
decreased blood urea nitrogen ... 1 | 51
decreased body temperature 1 | 2
decreased circulating HDL chol... 1 | 68
decreased circulating alanine ... 1 | 47
decreased circulating aspartat... 1 | 34
decreased circulating bilirubi... 1 | 19
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased circulating triglyce... 1 | 79
decreased fasted circulating g... 1 | 65
decreased lean body mass 1 | 135
decreased mean corpuscular vol... 1 | 79
decreased prepulse inhibition 1 | 82
decreased total retina thickne... 1 | 17
edema 1 | 59
embryonic growth retardation 1 | 106
enlarged heart 1 | 210
enlarged lymph nodes 1 | 37
enlarged seminal vesicle 1 | 10
hydroencephaly 1 | 14
hydrometra 1 | 53
impaired righting response 1 | 26
improved glucose tolerance 1 | 79
increased anti-nuclear antigen... 1 | 19
increased blood urea nitrogen ... 1 | 48
increased body length 1 | 32
increased bone mineral content 1 | 108
increased circulating HDL chol... 1 | 80
increased circulating choleste... 1 | 66
increased circulating fructosa... 1 | 13
increased circulating potassiu... 1 | 29
increased circulating thyroxin... 1 | 7
increased circulating total pr... 1 | 28
increased erythrocyte cell num... 1 | 39
increased hematocrit 1 | 46
increased leukocyte cell numbe... 1 | 47
increased neutrophil cell numb... 1 | 46
increased or absent threshold ... 1 | 101
increased thermal nociceptive ... 1 | 9
male infertility 1 | 123
persistence of hyaloid vascula... 1 | 33
premature death 1 | 5
small adrenal glands 1 | 16
small lymph nodes 1 | 1
small testis 1 | 58
stereotypic behavior 1 | 3
trunk curl 1 | 16

Disease

ovarian cancer 67 | 8,520
Carcinoma 57 | 11,493
glioblastoma 56 | 5,792
osteosarcoma 54 | 7,950
ependymoma 47 | 4,679
medulloblastoma, large-cell 46 | 6,241
psoriasis 43 | 6,694
atypical teratoid / rhabdoid tumor 41 | 5,112
lung cancer 36 | 4,740
Astrocytoma, Pilocytic 33 | 3,081
Cancer 32 | 2,499
malignant mesothelioma 30 | 3,232
pancreatic cancer 30 | 2,398
Multiple myeloma 29 | 1,332
lung adenocarcinoma 29 | 2,716
oligodendroglioma 29 | 2,850
subependymal giant cell astrocytoma 29 | 2,287
intraductal papillary-mucinous neoplasm (IPMN) 28 | 3,291
invasive ductal carcinoma 28 | 2,951
acute quadriplegic myopathy 27 | 1,158
Breast cancer 26 | 3,578
adult high grade glioma 25 | 3,801
astrocytic glioma 25 | 2,597
intraductal papillary-mucinous adenoma (IPMA) 25 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 24 | 2,989
lung carcinoma 24 | 2,843
pancreatic ductal adenocarcinoma liver metastasis 23 | 1,962
non-small cell lung cancer 22 | 2,890
diabetes mellitus 21 | 1,728
group 3 medulloblastoma 21 | 4,104
primitive neuroectodermal tumor 21 | 3,035
pituitary cancer 20 | 1,972
pediatric high grade glioma 19 | 1,064
ulcerative colitis 19 | 1,819
Pick disease 16 | 1,894
group 4 medulloblastoma 16 | 1,855
interstitial cystitis 16 | 2,312
cystic fibrosis 15 | 1,696
ductal carcinoma in situ 15 | 1,745
tuberculosis 15 | 2,010
Waldenstrons macroglobulinemia 14 | 765
juvenile dermatomyositis 14 | 1,187
Duchenne muscular dystrophy 13 | 601
active Crohn's disease 13 | 922
astrocytoma 13 | 1,146
dermatomyositis 13 | 966
Autosomal recessive predisposition 12 | 1,442
Hermansky-Pudlak syndrome 12 | 42
Liver Cirrhosis, Experimental 12 | 769
Oculocutaneous albinism 11 | 29
Schizophrenia 11 | 1,160
Vascular disease 11 | 319
cutaneous lupus erythematosus 11 | 1,057
gastric carcinoma 11 | 807
Down syndrome 10 | 499
Prostatic Neoplasms 10 | 495
primary pancreatic ductal adenocarcinoma 10 | 1,109
Alzheimer's disease 9 | 658
Kidney cancer 9 | 2,613
Melanoma 9 | 711
Parkinson's disease 9 | 392
spina bifida 9 | 1,074
Carcinoma, Hepatocellular 8 | 228
Rheumatoid arthritis 8 | 1,191
breast carcinoma 8 | 1,638
colon cancer 8 | 1,478
pancreatic carcinoma 8 | 562
Bipolar Disorder 7 | 666
Liver carcinoma 7 | 240
Neoplasm Invasiveness 7 | 161
Neurodegenerative disease 7 | 414
adrenocortical carcinoma 7 | 1,428
autosomal dominant Emery-Dreifuss muscular dystrophy 7 | 510
nasopharyngeal carcinoma 7 | 1,058
non primary Sjogren syndrome sicca 7 | 891
Breast Neoplasms 6 | 445
Chediak-Higashi syndrome 6 | 26
Cognitive delay 6 | 608
Degenerative polyarthritis 6 | 115
Epilepsy 6 | 792
Global developmental delay 6 | 608
Griscelli syndrome 6 | 24
Intellectual disability 6 | 1,016
Lung Neoplasms 6 | 232
Mammary Neoplasms 6 | 425
Mental and motor retardation 6 | 608
Multiple Sclerosis 6 | 540
Neoplasm Metastasis 6 | 168
Osteoarthritis 6 | 184
Polycystic ovary syndrome 6 | 360
gastric cancer 6 | 459
medulloblastoma 6 | 720
Dull intelligence 5 | 645
Mental deficiency 5 | 645
Myocardial Ischemia 5 | 169
Poor school performance 5 | 645
Seizures 5 | 596
esophageal adenocarcinoma 5 | 737
fibroadenoma 5 | 559
mucosa-associated lymphoid tissue lymphoma 5 | 484

Tissue

Endocrine System 100 | 18,159
Female tissues 100 | 17,400
Skin and soft tissues 100 | 17,230
Liver and Pancreas 99 | 16,750
Respiratory system 99 | 16,393
Urinary Tract 99 | 16,678
Blood and immune system 98 | 16,909
Male tissues 98 | 17,142
Nervous System 98 | 16,725
Digestive Tract 97 | 17,369
Cardiovascular System 95 | 15,192

Target Family

Non-IDG 54 | 12,091
Enzyme 37 | 4,145
Transporter 7 | 473
Epigenetic 1 | 242
GPCR 1 | 408
Ion Channel 1 | 344

GO Component

melanosome 101 | 101
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Transient receptor potential cation channel subfamily V member 2 TRPV2 Tchem Ion Channel -2.28525 197.9 203
Staphylococcal nuclease domain-containing protein 1 SND1 Tbio Epigenetic -2.35812 225.9 175
Transmembrane glycoprotein NMB GPNMB Tbio Non-IDG -2.05817 130.8 293
5,6-dihydroxyindole-2-carboxylic acid oxidase TYRP1 Tbio Enzyme -2.95336 876.7 309
Unconventional myosin-VIIa MYO7A Tbio Non-IDG -2.14713 133.5 129
Programmed cell death 6-interacting protein PDCD6IP Tbio Non-IDG -1.59404 35.1 216
Erythrocyte band 7 integral membrane protein STOM Tbio Non-IDG -2.27504 176.9 163
Ankyrin repeat domain-containing protein 27 ANKRD27 Tbio Non-IDG -1.12548 14.6 65
G-protein coupled receptor 143 GPR143 Tbio GPCR -1.72669 53.7 93
Transferrin receptor protein 1 TFRC Tbio Non-IDG -3.43851 2558.3 1677