Development Level

Tbio 30 | 11,445
Tdark 3 | 6,588
Tchem 1 | 1,598

Collection

Kinase: IDG Consortium (Target... 1 | 125
RFA-RM-18-021 1 | 328

IMPC Phenotype

preweaning lethality, complete... 7 | 979
abnormal embryo size 4 | 220
embryonic lethality prior to t... 4 | 278
embryonic lethality prior to o... 3 | 239
abnormal heart morphology 2 | 162
abnormal neural tube closure 2 | 46
abnormal placenta size 2 | 20
decreased leukocyte cell numbe... 2 | 73
embryonic growth retardation 2 | 106
pale yolk sac 2 | 25
abnormal bone structure 1 | 187
abnormal embryo turning 1 | 31
abnormal eye morphology 1 | 68
abnormal forebrain development 1 | 20
abnormal spleen morphology 1 | 55
abnormal tail bud morphology 1 | 8
decreased anxiety-related resp... 1 | 12
decreased circulating calcium ... 1 | 36
decreased vertical activity 1 | 208
enlarged heart 1 | 210
enlarged uterus 1 | 11
hydrometra 1 | 53
increased body length 1 | 32
increased fasted circulating g... 1 | 76
increased mean corpuscular hem... 1 | 96
increased monocyte cell number 1 | 63
increased or absent threshold ... 1 | 101
pale liver 1 | 6
pallor 1 | 34
prolonged PR interval 1 | 15
small spleen 1 | 19
small superior vagus ganglion 1 | 74

Disease

osteosarcoma 24 | 7,950
ovarian cancer 19 | 8,520
Carcinoma 16 | 11,493
medulloblastoma, large-cell 11 | 6,241
psoriasis 11 | 6,694
glioblastoma 9 | 5,792
group 3 medulloblastoma 9 | 4,104
atypical teratoid / rhabdoid tumor 8 | 5,112
Kidney cancer 6 | 2,613
astrocytic glioma 6 | 2,597
ependymoma 6 | 4,679
lung cancer 6 | 4,740
malignant mesothelioma 6 | 3,232
oligodendroglioma 6 | 2,850
Endometriosis 5 | 540
Rheumatoid arthritis 5 | 1,191
primitive neuroectodermal tumor 5 | 3,035
Breast cancer 4 | 3,578
Liver cancer 4 | 604
Pick disease 4 | 1,894
astrocytoma 4 | 1,146
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
Breast Neoplasms 3 | 445
Mammary Neoplasms 3 | 425
acute quadriplegic myopathy 3 | 1,158
group 4 medulloblastoma 3 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
lung adenocarcinoma 3 | 2,716
pituitary cancer 3 | 1,972
spina bifida 3 | 1,074
tuberculosis 3 | 2,010
tuberculosis and treatment for 6 months 3 | 409
Cancer 2 | 2,499
Cognitive delay 2 | 608
Congenital heart disease 2 | 93
Endometrial cancer 2 | 311
Epilepsy 2 | 792
FG syndrome 2 | 16
Feeding difficulties 2 | 127
Global developmental delay 2 | 608
Intellectual disability 2 | 1,016
Melanoma 2 | 711
Mental Depression 2 | 333
Mental and motor retardation 2 | 608
Multiple myeloma 2 | 1,332
Ohdo syndrome 2 | 5
Schizophrenia 2 | 1,160
Seizures 2 | 596
Waldenstrons macroglobulinemia 2 | 765
acute myeloid leukemia 2 | 783
adrenocortical carcinoma 2 | 1,428
adult high grade glioma 2 | 3,801
dermatomyositis 2 | 966
diabetes mellitus 2 | 1,728
hepatocellular carcinoma 2 | 547
hereditary spastic paraplegia 2 | 318
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
medulloblastoma 2 | 720
subependymal giant cell astrocytoma 2 | 2,287
tuberculosis and treatment for 3 months 2 | 179
ulcerative colitis 2 | 1,819
Anteriorly placed anus 1 | 7
Atypical autism 1 | 26
Biotinidase deficiency 1 | 14
Birthmark 1 | 35
Breast fibroadenoma 1 | 8
Bulimia nervosa 1 | 14
Cafe-au-Lait Spots 1 | 37
Cellulitis 1 | 20
Choanal Atresia 1 | 42
Claw hand 1 | 26
Clonus 1 | 18
Connective tissue cancer 1 | 10
Cornelia de Lange syndrome 1 | 21
Deep philtrum 1 | 21
Depressed philtrum 1 | 21
Farber lipogranulomatosis 1 | 9
Full lower lip 1 | 64
Generalized hypotonia 1 | 37
High pitched voice 1 | 23
Hypernasal voice 1 | 39
Hypoplasia of scrotum 1 | 24
Joint laxity 1 | 54
Leiomyoma 1 | 32
Leiomyosarcoma 1 | 24
Marfanoid body habitus 1 | 11
Narrow face 1 | 54
Narrow nose 1 | 20
Nasal voice 1 | 39
Obsessive compulsive behavior 1 | 25
Opitz-GBBB syndrome 1 | 18
Pinched bridge of nose 1 | 14
Pinched nasal bridge 1 | 14
Postnatal microcephaly 1 | 24
Prominent lower lip 1 | 64
Single transverse palmar crease 1 | 29
Stricture of anus 1 | 13
Thin face 1 | 54
Uterine fibroid 1 | 28
Vestibular nystagmus 1 | 6

Tissue

Blood and immune system 34 | 16,909
Cardiovascular System 34 | 15,192
Digestive Tract 34 | 17,369
Endocrine System 34 | 18,159
Female tissues 34 | 17,400
Liver and Pancreas 34 | 16,750
Male tissues 34 | 17,142
Nervous System 34 | 16,725
Respiratory system 34 | 16,393
Skin and soft tissues 34 | 17,230
Urinary Tract 34 | 16,678

Target Family

Enzyme 28 | 4,145
Non-IDG 4 | 12,091
Kinase 2 | 634

GO Component

mediator complex 34 | 34
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

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