Development Level

Tbio 6 | 11,445
Tchem 1 | 1,598

IMPC Phenotype

abnormal bone structure 1 | 187
abnormal limb position 1 | 3
abnormal skin morphology 1 | 50
decreased body length 1 | 101
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased grip strength 1 | 116
decreased heart rate 1 | 18
fusion of vertebral arches 1 | 7
increased total body fat amoun... 1 | 134
preweaning lethality, incomple... 1 | 499
prolonged RR interval 1 | 8
thin skin 1 | 2
vertebral fusion 1 | 23
vertebral transformation 1 | 12

Disease

medulloblastoma, large-cell 5 | 6,241
osteosarcoma 5 | 7,950
ovarian cancer 5 | 8,520
atypical teratoid / rhabdoid tumor 4 | 5,112
glioblastoma 4 | 5,792
Autosomal recessive predisposition 3 | 1,442
Bruck syndrome 3 | 10
Carcinoma 3 | 11,493
Dentinogenesis imperfecta 3 | 25
Osteogenesis imperfecta 3 | 34
Osteogenesis imperfecta type 2 3 | 8
Osteogenesis imperfecta type III (disorder) 3 | 11
Osteogenesis imperfecta, dominant perinatal lethal 3 | 5
Rheumatoid arthritis 3 | 1,191
ependymoma 3 | 4,679
group 3 medulloblastoma 3 | 4,104
lung adenocarcinoma 3 | 2,716
lung cancer 3 | 4,740
osteogenesis imperfecta type 3 3 | 11
Acquired scoliosis 2 | 281
Astrocytoma, Pilocytic 2 | 3,081
Atrial Fibrillation 2 | 124
Atrioventricular block 2 | 35
Blue sclera 2 | 32
Breast cancer 2 | 3,578
Cardiomyopathy 2 | 116
Cervical incompetence 2 | 6
Congenital heart disease 2 | 93
Curvature of spine 2 | 282
Exophthalmos 2 | 112
Familial atrial fibrillation 2 | 23
Frequent fractures 2 | 53
Holt-Oram syndrome 2 | 12
Hypoplastic Left Heart Syndrome 2 | 14
Increased fracture rate 2 | 53
Multiple fractures present at birth 2 | 5
Multiple myeloma 2 | 1,332
Osteogenesis imperfecta type IV (disorder) 2 | 10
Pectus excavatum 2 | 100
Prominent eyes 2 | 96
Prominent globes 2 | 96
Protruding eyes 2 | 96
Structure of wormian bone 2 | 24
Varying degree of multiple fractures 2 | 53
Ventricular Septal Defects 2 | 119
acute quadriplegic myopathy 2 | 1,158
adrenocortical carcinoma 2 | 1,428
astrocytoma 2 | 1,146
cystic fibrosis 2 | 1,696
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
lung carcinoma 2 | 2,843
non-small cell lung cancer 2 | 2,890
oligodendroglioma 2 | 2,850
osteogenesis imperfecta type 4 2 | 10
pediatric high grade glioma 2 | 1,064
psoriasis 2 | 6,694
Abnormal nasal morphology 1 | 16
Abnormal vertebral bodies 1 | 16
Abnormality of the metacarpal bones 1 | 17
Acheiropody 1 | 4
Atrial heart septal defect 1 | 18
Broad hallux 1 | 29
Carpal bone anomalies 1 | 5
Collapse of vertebra 1 | 14
Coloboma 1 | 51
Compression fracture of vertebral column 1 | 14
Congenital anomaly of spine 1 | 16
Congenital hypothyroidism 1 | 26
Congenital pectus carinatum 1 | 52
Discordant ventriculoarterial connection 1 | 17
Ebstein anomaly 1 | 16
Heart Septal Defects, Ventricular 1 | 6
Hip joint varus deformity - observation 1 | 24
Hyperkyphosis 1 | 111
Hypersomnia 1 | 8
Keratoconjunctivitis sicca 1 | 25
Kyphosis deformity of spine 1 | 114
Multiple vertebral anomalies 1 | 16
Ostium secundum atrial septal defect 1 | 9
POLYDACTYLY, POSTAXIAL 1 | 13
Partial duplication of thumb phalanx 1 | 6
Preauricular Fistulae, Congenital 1 | 27
Preauricular dimple 1 | 27
Preauricular sinus 1 | 27
Prevention of Cardiac Transplant Rejection 1 | 15
Prevention of Kidney Transplant Rejection 1 | 17
Prevention of Liver Transplant Rejection 1 | 15
Progressive mental retardation 1 | 37
Pulmonary valve stenosis 1 | 9
Radial aplasia/hypoplasia 1 | 29
Severe Recalcitrant Psoriasis 1 | 12
Sick sinus syndrome 1 | 15
Tear film insufficiency 1 | 15
Thumb aplasia 1 | 16
Thyroid Agenesis 1 | 5
Thyroid Hypoplasia 1 | 4
Tricuspid atresia 1 | 7
Triphalangeal thumb 1 | 9
ulnar-mammary syndrome 1 | 8

Tissue

Blood and immune system 7 | 16,909
Cardiovascular System 7 | 15,192
Female tissues 7 | 17,400
Urinary Tract 7 | 16,678
Digestive Tract 6 | 17,369
Endocrine System 6 | 18,159
Liver and Pancreas 6 | 16,750
Male tissues 6 | 17,142
Respiratory system 6 | 16,393
Skin and soft tissues 6 | 17,230
Nervous System 5 | 16,725

Target Family

Enzyme 2 | 4,145
Non-IDG 2 | 12,091
Transcription Factor 2 | 1,400
Epigenetic 1 | 242

GO Component

macromolecular complex 7 | 7
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Heterogeneous nuclear ribonucleoprotein U HNRNPU Tbio Non-IDG -2.33813 207.8 169
Chromobox protein homolog 5 CBX5 Tbio Epigenetic -1.90801 83.4 624
Cartilage-associated protein CRTAP Tbio Non-IDG -1.47844 29.1 199
Prolyl 3-hydroxylase 1 P3H1 Tbio Enzyme -1.47252 31.3 199
Homeobox protein Nkx-2.5 NKX2-5 Tbio Transcription Factor -2.79738 600.1 385
Peptidyl-prolyl cis-trans isomerase B PPIB Tchem Enzyme -2.24866 187.1 304
T-box transcription factor TBX5 TBX5 Tbio Transcription Factor -2.38269 244.4 198