Development Level

Tbio 2 | 11,445

Disease

Atrophy of cerebellum 2 | 103
Autosomal recessive predisposition 2 | 1,442
Babinski Reflex 2 | 100
Carcinoma 2 | 11,493
Cerebellar Ataxia 2 | 304
Cerebellar degeneration 2 | 103
Chronic progressive external ophthalmoplegia 2 | 26
Deglutition Disorders 2 | 132
Dysarthria 2 | 192
Gait Ataxia 2 | 51
Infratentorial atrophy 2 | 103
Neurodegenerative disease 2 | 414
Paraplegia 2 | 74
astrocytic glioma 2 | 2,597
oligodendroglioma 2 | 2,850
ovarian cancer 2 | 8,520
16q24.3 microdeletion syndrome 1 | 6
Acquired scoliosis 1 | 281
Adult onset 1 | 82
Ataxia, Appendicular 1 | 25
Ataxia, Spinocerebellar 1 | 16
Autosomal dominant cerebellar ataxia 1 | 33
Blau syndrome 1 | 9
Blepharoptosis 1 | 231
Cerebellar Dysmetria 1 | 56
Cerebral atrophy 1 | 178
Congenital pes cavus 1 | 88
Curvature of spine 1 | 282
Decreased lower limb vibratory sense 1 | 13
Defective or absent horizontal voluntary eye movements 1 | 25
Degeneration of the lateral corticospinal tracts 1 | 6
Dysdiadochokinesis 1 | 25
Dysmetric saccades 1 | 9
Dystonia 1 | 164
Dystonic disease 1 | 106
Early myoclonic encephalopathy 1 | 15
Epilepsies, Myoclonic 1 | 32
Forgetful 1 | 40
Generalized myoclonic seizures 1 | 30
Glomerulonephritis 1 | 46
Hereditary spastic paraplegia 7 1 | 2
Highly variable severity 1 | 157
Hyperreflexia 1 | 209
Increased intramyocellular lipid droplets 1 | 13
Infantile onset 1 | 238
Lateral sclerosis 1 | 15
Lower limb hyperreflexia 1 | 10
Lower limb spasticity 1 | 10
Memory Loss 1 | 40
Memory impairment 1 | 40
Monoparesis - leg 1 | 27
Muscle Spasticity 1 | 195
Muscle Weakness 1 | 170
Myoclonic Epilepsies, Progressive 1 | 44
Myoclonus 1 | 74
Nephrotic Syndrome 1 | 78
Neurogenic Muscular Atrophy 1 | 139
Neurogenic muscle atrophy, especially in the lower limbs 1 | 139
Neuropathy 1 | 261
Nystagmus 1 | 317
Nystagmus, End-Position 1 | 12
Oculomotor apraxia 1 | 25
Ophthalmoparesis 1 | 11
Optic Atrophy 1 | 242
Osteogenesis imperfecta 1 | 34
Overactive bladder syndrome 1 | 14
Paraparesis, Spastic 1 | 16
Peripheral sensorimotor neuropathy 1 | 16
Pick disease 1 | 1,894
Progressive disorder 1 | 142
Proteinuria 1 | 144
Ptosis 1 | 48
SPASTIC ATAXIA 5, AUTOSOMAL RECESSIVE 1 | 1
SPASTIC PARAPLEGIA 7, AUTOSOMAL RECESSIVE 1 | 1
SPINOCEREBELLAR ATAXIA 28 1 | 1
Skeletal muscle atrophy 1 | 139
Slow progression 1 | 89
Slowed saccades 1 | 12
Spastic Ataxia 1 | 18
Spastic Paraplegia 1 | 42
Spastic gait 1 | 23
Sphincter disturbances 1 | 16
Spinocerebellar Ataxias 1 | 34
Tonic - clonic seizures 1 | 44
Urgency frequency syndrome 1 | 14
Urgency of micturition 1 | 14
Urinary Incontinence 1 | 50
Variable expressivity 1 | 157
Weakness of lower limb 1 | 27
adult high grade glioma 1 | 3,801
glioblastoma 1 | 5,792
hereditary spastic paraplegia 1 | 318
interstitial cystitis 1 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 1 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 1 | 2,989
medulloblastoma, large-cell 1 | 6,241
muscle degeneration 1 | 139
osteosarcoma 1 | 7,950
spinocerebellar ataxia type 28 1 | 3
ulcerative colitis 1 | 1,819

Tissue

Blood and immune system 2 | 16,909
Cardiovascular System 2 | 15,192
Digestive Tract 2 | 17,369
Endocrine System 2 | 18,159
Female tissues 2 | 17,400
Liver and Pancreas 2 | 16,750
Male tissues 2 | 17,142
Nervous System 2 | 16,725
Respiratory system 2 | 16,393
Skin and soft tissues 2 | 17,230
Urinary Tract 2 | 16,678

Target Family

Enzyme 2 | 4,145

GO Component

m-AAA complex 2 | 2
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
AFG3-like protein 2 AFG3L2 Tbio Enzyme -1.58716 39.9 164
Paraplegin SPG7 Tbio Enzyme -2.81408 647.5 238