Development Level

Tbio 142 | 10,625
Tchem 38 | 1,890
Tclin 18 | 602
Tdark 12 | 7,003

IMPC Phenotype

preweaning lethality, complete... 8 | 633
short tibia 7 | 82
abnormal behavior 6 | 226
decreased total body fat amoun... 5 | 186
hypoactivity 4 | 89
increased mean corpuscular hem... 4 | 93
preweaning lethality, incomple... 4 | 260
decreased body length 3 | 108
decreased body weight 3 | 174
decreased bone mineral density 3 | 126
decreased erythrocyte cell num... 3 | 43
impaired glucose tolerance 3 | 52
increased bone mineral content 3 | 92
abnormal bone structure 2 | 131
abnormal skin morphology 2 | 23
decreased B cell number 2 | 30
decreased Ly6C low monocyte nu... 2 | 23
decreased blood urea nitrogen ... 2 | 31
decreased grip strength 2 | 123
decreased monocyte cell number 2 | 28
decreased rib number 2 | 59
improved glucose tolerance 2 | 56
increased B cell number 2 | 23
increased NK cell number 2 | 19
increased bone mineral density 2 | 52
increased circulating alkaline... 2 | 119
small adrenal glands 2 | 15
straub tail 2 | 26
abnormal body wall morphology 1 | 7
abnormal bone mineralization 1 | 55
abnormal coat appearance 1 | 25
abnormal embryo size 1 | 112
abnormal femur morphology 1 | 14
abnormal gait 1 | 51
abnormal lung morphology 1 | 15
abnormal motor capabilities-co... 1 | 4
abnormal seminal vesicle morph... 1 | 47
abnormal skin coloration 1 | 18
abnormal thoracic cage shape 1 | 3
abnormal vibrissa morphology 1 | 17
abnormal vocalization 1 | 21
decreased CD4-positive, CD25-p... 1 | 24
decreased CD4-positive, alpha ... 1 | 19
decreased CD5-positive Ly6C-po... 1 | 4
decreased CD8-positive, alpha-... 1 | 26
decreased KLRG1+ CD8 alpha bet... 1 | 8
decreased Ly6C high monocyte n... 1 | 18
decreased T cell number 1 | 31
decreased bone mineral content 1 | 157
decreased circulating LDL chol... 1 | 37
decreased circulating aspartat... 1 | 27
decreased circulating bilirubi... 1 | 14
decreased circulating glucose ... 1 | 121
decreased circulating iron lev... 1 | 25
decreased circulating serum al... 1 | 79
decreased circulating sodium l... 1 | 18
decreased effector memory CD4-... 1 | 6
decreased eosinophil cell numb... 1 | 41
decreased fasted circulating g... 1 | 49
decreased gamma-delta T cell n... 1 | 18
decreased lean body mass 1 | 195
decreased leukocyte cell numbe... 1 | 54
decreased mature B cell number 1 | 25
decreased mean corpuscular hem... 1 | 34
decreased memory-marker CD4-po... 1 | 4
decreased neutrophil cell numb... 1 | 37
decreased prepulse inhibition 1 | 52
decreased total retina thickne... 1 | 20
embryonic lethality prior to o... 1 | 148
embryonic lethality prior to t... 1 | 187
enlarged spleen 1 | 26
increased CD4-positive, alpha ... 1 | 15
increased CD8-positive, alpha-... 1 | 11
increased T cell number 1 | 15
increased alpha-beta T cell nu... 1 | 9
increased blood urea nitrogen ... 1 | 44
increased circulating HDL chol... 1 | 63
increased circulating LDL chol... 1 | 15
increased circulating magnesiu... 1 | 10
increased circulating potassiu... 1 | 31
increased effector memory CD8-... 1 | 14
increased exploration in new e... 1 | 56
increased lean body mass 1 | 107
increased leukocyte cell numbe... 1 | 37
increased mature B cell number 1 | 12
increased neutrophil cell numb... 1 | 15
premature death 1 | 5
protruding tongue 1 | 1
thrombocytosis 1 | 23
tremors 1 | 34

Disease

ovarian cancer 126 | 8,491
osteosarcoma 90 | 7,933
glioblastoma 85 | 5,572
medulloblastoma, large-cell 78 | 6,234
psoriasis 74 | 6,685
lung cancer 69 | 4,473
malignant mesothelioma 57 | 3,163
pilocytic astrocytoma 49 | 3,086
atypical teratoid / rhabdoid tumor 48 | 4,369
lung carcinoma 46 | 2,844
tuberculosis 46 | 1,563
intraductal papillary-mucinous neoplasm (IPMN) 44 | 3,289
invasive ductal carcinoma 44 | 2,950
pediatric high grade glioma 43 | 2,712
subependymal giant cell astrocytoma 43 | 2,287
Cancer 42 | 2,346
diabetes mellitus 41 | 1,663
intraductal papillary-mucinous adenoma (IPMA) 41 | 2,956
lung adenocarcinoma 41 | 2,714
non-small cell lung cancer 41 | 2,798
oligodendroglioma 37 | 2,849
ulcerative colitis 37 | 2,087
interstitial cystitis 34 | 2,299
Breast cancer 33 | 3,098
astrocytoma 32 | 1,493
intraductal papillary-mucinous carcinoma (IPMC) 32 | 2,988
group 4 medulloblastoma 31 | 1,875
pancreatic cancer 31 | 2,300
primitive neuroectodermal tumor 28 | 3,031
pancreatic ductal adenocarcinoma liver metastasis 27 | 1,795
posterior fossa group A ependymoma 26 | 1,511
Multiple myeloma 24 | 1,327
Pick disease 23 | 1,893
cystic fibrosis 23 | 1,670
Rheumatoid Arthritis 22 | 1,170
acute quadriplegic myopathy 22 | 1,157
cutaneous lupus erythematosus 22 | 1,056
ependymoma 22 | 2,514
astrocytic glioma 21 | 2,241
breast carcinoma 21 | 1,614
dermatomyositis 21 | 966
primary pancreatic ductal adenocarcinoma 21 | 1,271
group 3 medulloblastoma 20 | 2,254
Alzheimer's disease 19 | 644
Down syndrome 19 | 548
Neurodegenerative disease 19 | 383
gastric carcinoma 19 | 832
Waldenstrons macroglobulinemia 18 | 764
colon cancer 18 | 1,475
juvenile dermatomyositis 18 | 1,189
medulloblastoma 18 | 1,524
posterior fossa group B ependymoma 18 | 1,530
adult high grade glioma 17 | 2,148
ductal carcinoma in situ 17 | 1,745
Carcinoma 16 | 2,147
pituitary cancer 16 | 1,972
Atopic dermatitis 15 | 944
Coronary artery disease 15 | 240
atypical teratoid/rhabdoid tumor 15 | 1,095
esophageal adenocarcinoma 15 | 737
Heart disease 14 | 279
Kidney disease 14 | 397
Obesity 14 | 616
active Crohn's disease 14 | 918
adrenocortical carcinoma 14 | 1,427
Atherosclerosis 13 | 275
Duchenne muscular dystrophy 13 | 602
mucosa-associated lymphoid tissue lymphoma 13 | 480
primary Sjogren syndrome 13 | 788
Asthma 12 | 349
Hypertension 12 | 293
Multiple Sclerosis 12 | 498
Cerebrovascular disease 11 | 231
Parkinson's disease 11 | 364
nephrosclerosis 11 | 329
non primary Sjogren syndrome sicca 11 | 840
pancreatic carcinoma 11 | 567
tuberculosis and treatment for 6 months 11 | 686
Epilepsy 10 | 346
Neuronal ceroid lipofuscinosis 10 | 28
Prostatic Neoplasms 10 | 471
aldosterone-producing adenoma 10 | 664
nasopharyngeal carcinoma 10 | 1,056
sarcoidosis 10 | 368
sonic hedgehog group medulloblastoma 10 | 1,482
Autistic Disorder 9 | 320
Crohn's disease 9 | 304
Dementia 9 | 129
Intellectual disability 9 | 573
Lung Neoplasms 9 | 171
Mucopolysaccharidosis 9 | 24
gastric cancer 9 | 436
interstitial lung disease 9 | 292
Arthritis 8 | 248
Gaucher's disease 8 | 25
Hermansky-Pudlak syndrome 8 | 43
IGA Glomerulonephritis 8 | 454
Vascular disease 8 | 281
fibroadenoma 8 | 557
tuberculosis and treatment for 3 months 8 | 327

Tissue

Digestive Tract 209 | 18,472
Nervous System 209 | 18,560
Urinary Tract 209 | 18,443
Blood and immune system 208 | 17,994
Female tissues 208 | 18,646
Cardiovascular System 207 | 17,957
Endocrine System 207 | 18,511
Liver and Pancreas 207 | 18,135
Skin and soft tissues 207 | 18,114
Male tissues 206 | 17,968
Respiratory system 206 | 17,483

Target Family

Non-IDG 98 | 11,969
Enzyme 91 | 4,146
Transporter 7 | 473
Ion Channel 6 | 341
Kinase 4 | 634
GPCR 3 | 408
Transcription Factor 1 | 1,400

GO Component

lysosome 210 | 210
nucleus 5,106 | 5,106
cytoplasm 4,984 | 4,984
plasma membrane 4,118 | 4,118
integral component of membrane 3,679 | 3,679
cytosol 3,264 | 3,264
extracellular exosome 2,757 | 2,757
nucleoplasm 2,716 | 2,716
membrane 1,906 | 1,906
extracellular region 1,493 | 1,493
integral component of plasma m... 1,406 | 1,406
extracellular space 1,304 | 1,304
mitochondrion 1,231 | 1,231
Golgi apparatus 864 | 864
endoplasmic reticulum 859 | 859
endoplasmic reticulum membrane 848 | 848
nucleolus 815 | 815
Golgi membrane 659 | 659
perinuclear region of cytoplas... 611 | 611
cell surface 594 | 594
intracellular 548 | 548
intracellular membrane-bounded... 536 | 536
cell junction 451 | 451
mitochondrial inner membrane 425 | 425
centrosome 409 | 409
focal adhesion 383 | 383
protein complex 355 | 355
cytoskeleton 343 | 343
dendrite 329 | 329
mitochondrial matrix 322 | 322
cell-cell adherens junction 307 | 307
neuronal cell body 303 | 303
microtubule 294 | 294
lysosomal membrane 278 | 278
apical plasma membrane 277 | 277
proteinaceous extracellular ma... 244 | 244
neuron projection 229 | 229
nuclear membrane 218 | 218
early endosome 217 | 217
axon 214 | 214
endosome 208 | 208
actin cytoskeleton 205 | 205
external side of plasma membra... 205 | 205
postsynaptic membrane 204 | 204
extracellular matrix 198 | 198
nuclear speck 197 | 197
membrane raft 196 | 196
endoplasmic reticulum lumen 192 | 192
transcription factor complex 184 | 184
endosome membrane 182 | 182
early endosome membrane 180 | 180
basolateral plasma membrane 174 | 174
nuclear chromatin 169 | 169
synapse 166 | 166
cell-cell junction 161 | 161
nuclear envelope 156 | 156
lamellipodium 153 | 153
mitochondrial outer membrane 148 | 148
blood microparticle 147 | 147
myelin sheath 144 | 144
postsynaptic density 144 | 144
cytoplasmic vesicle 143 | 143
microtubule organizing center 137 | 137
cytoplasmic, membrane-bounded ... 132 | 132
ER to Golgi transport vesicle ... 131 | 131
microtubule cytoskeleton 127 | 127
receptor complex 127 | 127
phagocytic vesicle membrane 126 | 126
cytoplasmic vesicle membrane 125 | 125
midbody 125 | 125
trans-Golgi network 124 | 124
cell cortex 119 | 119
cilium 118 | 118
late endosome 116 | 116
spindle 116 | 116
intracellular ribonucleoprotei... 114 | 114
vesicle 112 | 112
Z disc 110 | 110
bicellular tight junction 110 | 110
anchored component of membrane 109 | 109
growth cone 109 | 109
integral component of lumenal ... 108 | 108
late endosome membrane 107 | 107
endomembrane system 106 | 106
centriole 105 | 105
recycling endosome 104 | 104
spindle pole 104 | 104
perikaryon 103 | 103
integral component of endoplas... 101 | 101
intermediate filament 101 | 101
melanosome 101 | 101
chromosome 100 | 100
dendritic spine 99 | 99
ubiquitin ligase complex 99 | 99
peroxisome 98 | 98
nuclear matrix 97 | 97
PML body 94 | 94
Golgi lumen 93 | 93
keratin filament 93 | 93
trans-Golgi network membrane 92 | 92

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Paired box protein Pax-2 PAX2 Tbio Transcription Factor -2.66256 471.8 306
Dipeptidyl peptidase 1 CTSC Tchem Enzyme -3.24582 1740.5 143
Cystatin-C CST3 Tbio Non-IDG -3.48935 3020.7 756
Low-density lipoprotein receptor LDLR Tchem Non-IDG -3.04462 893.1 512
Two pore calcium channel protein 1 TPCN1 Tbio Ion Channel -1.84159 59.3 38
Pleckstrin homology domain-containing family F member 1 PLEKHF1 Tbio Non-IDG -1.78639 62.5 99
Mammalian ependymin-related protein 1 EPDR1 Tbio Non-IDG -1.15636 15.5 108
Synaptotagmin-7 SYT7 Tbio Non-IDG -1.72363 48.4 144
Hyaluronidase-1 HYAL1 Tbio Enzyme -1.85417 78.6 191
Transmembrane protein 59 TMEM59 Tbio Non-IDG -1.33352 18.7 53