Development Level

Tbio 47 | 11,445
Tchem 4 | 1,598
Tclin 3 | 613

IMPC Phenotype

preweaning lethality, complete... 4 | 979
preweaning lethality, incomple... 3 | 499
abnormal retina morphology 2 | 71
improved glucose tolerance 2 | 79
increased mean corpuscular hem... 2 | 96
increased mean corpuscular vol... 2 | 92
mammalian phenotype 2 | 17
prenatal lethality 2 | 28
abnormal behavior 1 | 298
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal coat appearance 1 | 31
abnormal embryo size 1 | 220
abnormal gait 1 | 69
abnormal head morphology 1 | 10
abnormal lens morphology 1 | 81
abnormal locomotor behavior 1 | 24
abnormal snout morphology 1 | 23
abnormal startle reflex 1 | 15
abnormal tail movements 1 | 12
cataract 1 | 92
curly tail 1 | 1
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased cardiac muscle contr... 1 | 11
decreased caudal vertebrae num... 1 | 53
decreased circulating HDL chol... 1 | 68
decreased circulating alkaline... 1 | 46
decreased circulating choleste... 1 | 93
decreased circulating total pr... 1 | 49
decreased coping response 1 | 8
decreased fasted circulating g... 1 | 65
decreased startle reflex 1 | 75
decreased vertical activity 1 | 208
dilated heart left ventricle 1 | 11
hyperactivity 1 | 148
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
increased blood urea nitrogen ... 1 | 48
increased body weight 1 | 25
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating chloride... 1 | 41
increased circulating creatini... 1 | 38
increased circulating thyroxin... 1 | 7
increased fasted circulating g... 1 | 76
increased heart weight 1 | 62
increased hemoglobin content 1 | 45
increased mean platelet volume 1 | 45
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
kinked tail 1 | 2
prenatal lethality prior to he... 1 | 87
short tibia 1 | 97

Disease

Carcinoma 40 | 11,493
ovarian cancer 32 | 8,520
osteosarcoma 27 | 7,950
medulloblastoma, large-cell 25 | 6,241
psoriasis 24 | 6,694
atypical teratoid / rhabdoid tumor 23 | 5,112
Cancer 22 | 2,499
ependymoma 22 | 4,679
glioblastoma 20 | 5,792
lung cancer 19 | 4,740
pancreatic cancer 19 | 2,398
intraductal papillary-mucinous carcinoma (IPMC) 17 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 17 | 3,291
lung adenocarcinoma 17 | 2,716
non-small cell lung cancer 17 | 2,890
Breast cancer 16 | 3,578
Kidney cancer 16 | 2,613
ductal carcinoma in situ 16 | 1,745
interstitial cystitis 16 | 2,312
pituitary cancer 16 | 1,972
Astrocytoma, Pilocytic 15 | 3,081
adult high grade glioma 15 | 3,801
group 3 medulloblastoma 15 | 4,104
invasive ductal carcinoma 15 | 2,951
lung carcinoma 14 | 2,843
primitive neuroectodermal tumor 14 | 3,035
Autosomal recessive predisposition 13 | 1,442
cystic fibrosis 12 | 1,696
malignant mesothelioma 12 | 3,232
pancreatic ductal adenocarcinoma liver metastasis 12 | 1,962
spina bifida 12 | 1,074
intraductal papillary-mucinous adenoma (IPMA) 11 | 2,955
oligodendroglioma 11 | 2,850
Schizophrenia 10 | 1,160
ulcerative colitis 10 | 1,819
Prostatic Neoplasms 9 | 495
astrocytic glioma 9 | 2,597
nasopharyngeal carcinoma 9 | 1,058
Liver cancer 8 | 604
breast carcinoma 8 | 1,638
colon cancer 8 | 1,478
subependymal giant cell astrocytoma 8 | 2,287
Melanoma 7 | 711
Pick disease 7 | 1,894
active Crohn's disease 7 | 922
group 4 medulloblastoma 7 | 1,855
Breast Neoplasms 6 | 445
Lung Neoplasms 6 | 232
Mammary Neoplasms 6 | 425
Neoplasm Metastasis 6 | 168
Skin cancer 6 | 469
esophageal adenocarcinoma 6 | 737
gastric carcinoma 6 | 807
tuberculosis 6 | 2,010
Adenoma 5 | 167
Carcinoma, Hepatocellular 5 | 228
Disease Progression 5 | 136
Duchenne muscular dystrophy 5 | 601
Endometrial cancer 5 | 311
Endometriosis 5 | 540
Inflammatory bowel disease 5 | 151
Liver Cirrhosis, Experimental 5 | 769
Liver carcinoma 5 | 240
Muscle hypotonia 5 | 571
Stomach Neoplasms 5 | 300
primary pancreatic ductal adenocarcinoma 5 | 1,109
Alopecia 4 | 115
Animal Mammary Neoplasms 4 | 136
Cell Transformation, Neoplastic 4 | 97
Colorectal Neoplasms 4 | 243
Epilepsy 4 | 792
Intellectual disability 4 | 1,016
Kidney disease 4 | 430
Liver neoplasms 4 | 130
Mammary Neoplasms, Animal 4 | 136
Neoplastic Cell Transformation 4 | 89
Nonsyndromic deafness 4 | 142
Pancreatic Neoplasm 4 | 85
Pancreatic Neoplasms 4 | 85
Somatic mutation 4 | 61
active ulcerative colitis 4 | 764
acute quadriplegic myopathy 4 | 1,158
diabetes mellitus 4 | 1,728
hepatocellular carcinoma 4 | 547
juvenile dermatomyositis 4 | 1,187
medulloblastoma 4 | 720
mucosa-associated lymphoid tissue lymphoma 4 | 484
pediatric high grade glioma 4 | 1,064
Atopic dermatitis 3 | 952
Hypertension 3 | 396
Multiple Sclerosis 3 | 540
Psychotic Disorders 3 | 151
Seizures 3 | 596
Vascular disease 3 | 319
adrenocortical carcinoma 3 | 1,428
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 510
fibroadenoma 3 | 559
head and neck cancer 3 | 271
nephrosclerosis 3 | 333
urothelial carcinoma 3 | 318

Tissue

Digestive Tract 51 | 17,369
Endocrine System 51 | 18,159
Female tissues 51 | 17,400
Liver and Pancreas 51 | 16,750
Male tissues 51 | 17,142
Nervous System 51 | 16,725
Skin and soft tissues 51 | 17,230
Respiratory system 50 | 16,393
Urinary Tract 50 | 16,678
Blood and immune system 49 | 16,909
Cardiovascular System 49 | 15,192

Target Family

Non-IDG 38 | 12,091
Enzyme 8 | 4,145
GPCR 2 | 408
Ion Channel 2 | 344
Kinase 2 | 634
Transporter 2 | 473

GO Component

lateral plasma membrane 54 | 54
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Nuclear mitotic apparatus protein 1 NUMA1 Tbio Non-IDG -2.76544 575.8 235
Tubulin-specific chaperone D TBCD Tbio Non-IDG -1.71996 50.5 50
Neuronal vesicle trafficking-associated protein 1 NSG1 Tbio Non-IDG -1.15265 16.1 182
Serine/threonine-protein kinase MARK2 MARK2 Tchem Kinase -2.49873 272.3 322
Epithelial cell adhesion molecule EPCAM Tbio Non-IDG -3.20358 1618.6 2244
Microtubule cross-linking factor 1 MTCL1 Tbio Non-IDG -0.63960 4.60 21
Claudin-1 CLDN1 Tbio Non-IDG -2.07626 126.7 593
Potassium voltage-gated channel subfamily B member 1 KCNB1 Tclin Ion Channel -2.57484 386.0 303
Complement C1q tumor necrosis factor-related protein 5 C1QTNF5 Tbio Non-IDG -0.39794 1.27 209
Ras-related protein Rab-13 RAB13 Tbio Enzyme -1.40524 27.4 73