Development Level

Tbio 103 | 11,445
Tchem 9 | 1,598
Tdark 9 | 6,588
Tclin 1 | 613

IMPC Phenotype

preweaning lethality, complete... 13 | 979
preweaning lethality, incomple... 5 | 499
abnormal behavior 3 | 298
abnormal embryo size 3 | 220
decreased body weight 3 | 161
embryonic lethality prior to o... 3 | 239
hypoactivity 3 | 132
prolonged QT interval 3 | 38
abnormal body wall morphology 2 | 9
abnormal craniofacial morpholo... 2 | 33
abnormal epididymis morphology 2 | 42
abnormal response to new envir... 2 | 10
decreased circulating insulin ... 2 | 76
enlarged epididymis 2 | 31
increased circulating potassiu... 2 | 29
increased fasted circulating g... 2 | 76
increased lean body mass 2 | 172
increased leukocyte cell numbe... 2 | 47
increased startle reflex 2 | 112
prolonged ST segment 2 | 36
abnormal QT variability 1 | 10
abnormal eye morphology 1 | 68
abnormal eye size 1 | 7
abnormal gait 1 | 69
abnormal hindbrain morphology 1 | 10
abnormal hindlimb morphology 1 | 2
abnormal iris morphology 1 | 13
abnormal kidney morphology 1 | 65
abnormal lens morphology 1 | 81
abnormal limb position 1 | 3
abnormal midbrain morphology 1 | 10
abnormal neural tube closure 1 | 46
abnormal response to tactile s... 1 | 17
abnormal retinal inner nuclear... 1 | 8
abnormal skin morphology 1 | 50
abnormal sleep behavior 1 | 70
abnormal tail movements 1 | 12
abnormal testis morphology 1 | 43
abnormal thoracic cage shape 1 | 3
abnormal vibrissa morphology 1 | 25
alopecia 1 | 1
cataract 1 | 92
decreased IgE level 1 | 6
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 68
decreased circulating alkaline... 1 | 46
decreased circulating aspartat... 1 | 34
decreased circulating choleste... 1 | 93
decreased circulating creatini... 1 | 39
decreased circulating free fat... 1 | 31
decreased circulating lactate ... 1 | 3
decreased fasted circulating g... 1 | 65
decreased lean body mass 1 | 135
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular vol... 1 | 79
decreased prepulse inhibition 1 | 82
decreased red blood cell distr... 1 | 41
decreased total body fat amoun... 1 | 207
decreased total retina thickne... 1 | 17
edema 1 | 59
embryonic lethality prior to t... 1 | 278
enlarged kidney 1 | 14
enlarged lymph nodes 1 | 37
enlarged spleen 1 | 41
improved glucose tolerance 1 | 79
increased blood urea nitrogen ... 1 | 48
increased bone mineral content 1 | 108
increased circulating alkaline... 1 | 122
increased circulating glucose ... 1 | 24
increased circulating serum al... 1 | 22
increased circulating sodium l... 1 | 71
increased heart rate 1 | 23
increased heart weight 1 | 62
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased total body fat amoun... 1 | 134
limb grasping 1 | 41
mammalian phenotype 1 | 17
prenatal lethality prior to he... 1 | 87
prolonged PR interval 1 | 15
prolonged QRS complex duration 1 | 8
protruding tongue 1 | 3
short tibia 1 | 97
thrombocytosis 1 | 27
tremors 1 | 39
trunk curl 1 | 16

Disease

ovarian cancer 73 | 8,520
Carcinoma 53 | 11,493
osteosarcoma 43 | 7,950
medulloblastoma, large-cell 38 | 6,241
glioblastoma 36 | 5,792
psoriasis 29 | 6,694
ependymoma 27 | 4,679
atypical teratoid / rhabdoid tumor 26 | 5,112
lung cancer 26 | 4,740
tuberculosis 25 | 2,010
Rheumatoid arthritis 23 | 1,191
Multiple myeloma 19 | 1,332
adult high grade glioma 18 | 3,801
invasive ductal carcinoma 18 | 2,951
lung carcinoma 18 | 2,843
oligodendroglioma 18 | 2,850
pancreatic cancer 18 | 2,398
Astrocytoma, Pilocytic 17 | 3,081
intraductal papillary-mucinous neoplasm (IPMN) 17 | 3,291
group 3 medulloblastoma 16 | 4,104
malignant mesothelioma 16 | 3,232
pancreatic ductal adenocarcinoma liver metastasis 16 | 1,962
Systemic lupus erythematosus 15 | 194
diabetes mellitus 15 | 1,728
sarcoidosis 15 | 370
Breast cancer 14 | 3,578
Narcolepsy 14 | 72
Pick disease 14 | 1,894
adrenocortical carcinoma 14 | 1,428
breast carcinoma 14 | 1,638
group 4 medulloblastoma 14 | 1,855
intraductal papillary-mucinous carcinoma (IPMC) 14 | 2,989
Berylliosis 13 | 28
Diffuse cutaneous systemic sclerosis 13 | 17
Kidney cancer 13 | 2,613
Multiple Sclerosis, Susceptibility to 13 | 15
Narcolepsy-cataplexy 13 | 21
Rheumatoid Arthritis, Systemic Juvenile 13 | 16
Sarcoidosis 1 13 | 14
follicular lymphoma 13 | 20
juvenile dermatomyositis 13 | 1,187
limited scleroderma 13 | 19
primitive neuroectodermal tumor 13 | 3,035
astrocytic glioma 12 | 2,597
intraductal papillary-mucinous adenoma (IPMA) 12 | 2,955
non-small cell lung cancer 12 | 2,890
subependymal giant cell astrocytoma 12 | 2,287
acute quadriplegic myopathy 11 | 1,158
dermatomyositis 11 | 966
interstitial cystitis 11 | 2,312
pediatric high grade glioma 11 | 1,064
primary pancreatic ductal adenocarcinoma 11 | 1,109
ulcerative colitis 11 | 1,819
Multiple Sclerosis 10 | 540
Waldenstrons macroglobulinemia 10 | 765
lung adenocarcinoma 10 | 2,716
Down syndrome 9 | 499
astrocytoma 9 | 1,146
colon cancer 9 | 1,478
Autosomal recessive predisposition 8 | 1,442
Cancer 8 | 2,499
Neurodegenerative disease 8 | 414
active Crohn's disease 8 | 922
active ulcerative colitis 8 | 764
ductal carcinoma in situ 8 | 1,745
progressive supranuclear palsy 8 | 676
Duchenne muscular dystrophy 7 | 601
Intellectual disability 7 | 1,016
cystic fibrosis 7 | 1,696
esophageal adenocarcinoma 7 | 737
ARC syndrome 6 | 13
Schizophrenia 6 | 1,160
mucosa-associated lymphoid tissue lymphoma 6 | 484
pancreatic carcinoma 6 | 562
pituitary cancer 6 | 1,972
primary Sjogren syndrome 6 | 735
Alzheimer's disease 5 | 658
Juvenile rheumatoid arthritis 5 | 111
Liver disease 5 | 237
acute myeloid leukemia 5 | 783
aldosterone-producing adenoma 5 | 665
non primary Sjogren syndrome sicca 5 | 891
spina bifida 5 | 1,074
Absent reflex 4 | 92
Absent tendon reflex 4 | 92
Amyotrophic lateral sclerosis 4 | 451
Bipolar Disorder 4 | 666
Dull intelligence 4 | 645
Dysarthria 4 | 192
Epilepsy 4 | 792
Hypersensitivity reaction type II disease 4 | 253
Liver Cirrhosis, Experimental 4 | 769
Mental and motor retardation 4 | 608
Neuropathy 4 | 261
Reflex, Deep Tendon, Absent 4 | 92
Vasculitis 4 | 80
fibroadenoma 4 | 559
gastric carcinoma 4 | 807
hereditary spastic paraplegia 4 | 318
tuberculosis and treatment for 6 months 4 | 409

Tissue

Endocrine System 108 | 18,159
Blood and immune system 106 | 16,909
Cardiovascular System 106 | 15,192
Digestive Tract 106 | 17,369
Female tissues 106 | 17,400
Male tissues 106 | 17,142
Nervous System 106 | 16,725
Respiratory system 106 | 16,393
Skin and soft tissues 106 | 17,230
Liver and Pancreas 105 | 16,750
Urinary Tract 105 | 16,678

Target Family

Non-IDG 93 | 12,091
Enzyme 14 | 4,145
Transporter 8 | 473
Ion Channel 5 | 344
Kinase 2 | 634

GO Component

late endosome membrane 122 | 122
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Sorting nexin-14 SNX14 Tbio Non-IDG -0.86091 6.82 56
TIR domain-containing adapter molecule 2 TICAM2 Tbio Non-IDG -1.18212 14.6 258
High affinity nerve growth factor receptor NTRK1 Tclin Kinase -3.05841 1050.9 1092
WD repeat-containing protein 91 WDR91 Tbio Non-IDG -0.72903 5.46 54
ATP-binding cassette sub-family A member 5 ABCA5 Tbio Transporter -1.09683 13.2 131
MIT domain-containing protein 1 MITD1 Tbio Non-IDG -0.25556 2.10 59
Tumor susceptibility gene 101 protein TSG101 Tbio Non-IDG -2.47780 298.9 332
Lysosomal-associated transmembrane protein 4B LAPTM4B Tbio Non-IDG -1.90763 86.1 91
AP-5 complex subunit sigma-1 AP5S1 Tdark Non-IDG 0.00000 4
Transmembrane protein 165 TMEM165 Tbio Non-IDG -1.56011 39.2 89