Development Level

Tbio 79 | 10,625
Tchem 18 | 1,890
Tdark 11 | 7,003
Tclin 8 | 602

IMPC Term

preweaning lethality, complete... 6 | 633
abnormal behavior 3 | 226
decreased body weight 3 | 174
abnormal embryo size 2 | 112
decreased blood urea nitrogen ... 2 | 31
decreased grip strength 2 | 123
decreased mean corpuscular hem... 2 | 34
decreased total body fat amoun... 2 | 186
embryonic lethality prior to o... 2 | 148
impaired glucose tolerance 2 | 52
short tibia 2 | 82
abnormal body wall morphology 1 | 7
abnormal femur morphology 1 | 14
abnormal gait 1 | 51
abnormal hindbrain development 1 | 24
abnormal kidney morphology 1 | 30
abnormal midbrain development 1 | 22
abnormal motor capabilities/co... 1 | 4
abnormal neural tube closure 1 | 37
abnormal rib morphology 1 | 28
abnormal skin morphology 1 | 23
abnormal thoracic cage shape 1 | 3
decreased CD5-positive Ly6C-po... 1 | 4
decreased KLRG1+ CD8 alpha bet... 1 | 8
decreased Ly6C low monocyte nu... 1 | 23
decreased body length 1 | 108
decreased bone mineral content 1 | 157
decreased bone mineral density 1 | 126
decreased circulating alkaline... 1 | 41
decreased circulating aspartat... 1 | 27
decreased circulating bilirubi... 1 | 14
decreased circulating glucose ... 1 | 121
decreased leukocyte cell numbe... 1 | 54
decreased lumbar vertebrae num... 1 | 62
decreased memory-marker CD4-po... 1 | 4
decreased monocyte cell number 1 | 28
decreased total retina thickne... 1 | 20
embryonic lethality prior to t... 1 | 187
enlarged spleen 1 | 26
hyperactivity 1 | 108
hypoactivity 1 | 89
improved glucose tolerance 1 | 56
increased B cell number 1 | 23
increased NK cell number 1 | 19
increased body length 1 | 20
increased body weight 1 | 42
increased fasted circulating g... 1 | 68
increased hemoglobin content 1 | 45
increased leukocyte cell numbe... 1 | 37
increased mature B cell number 1 | 12
increased mean corpuscular hem... 1 | 93
increased neutrophil cell numb... 1 | 15
increased sacral vertebrae num... 1 | 62
preweaning lethality, incomple... 1 | 260
protruding tongue 1 | 1
thrombocytosis 1 | 23

Disease

ovarian cancer 74 | 8,484
osteosarcoma 62 | 7,933
psoriasis 48 | 6,685
medulloblastoma, large-cell 45 | 6,234
glioblastoma 43 | 5,572
lung cancer 37 | 4,466
atypical teratoid / rhabdoid tumor 31 | 4,369
malignant mesothelioma 26 | 3,162
Cancer 24 | 2,346
ependymoma 23 | 2,514
Breast cancer 22 | 3,094
intraductal papillary-mucinous carcinoma (IPMC) 22 | 2,988
intraductal papillary-mucinous adenoma (IPMA) 21 | 2,956
oligodendroglioma 21 | 2,849
pancreatic ductal adenocarcinoma liver metastasis 21 | 1,795
Multiple myeloma 20 | 1,327
intraductal papillary-mucinous neoplasm (IPMN) 20 | 3,289
tuberculosis 19 | 1,557
Pick disease 18 | 1,893
diabetes mellitus 18 | 1,663
pediatric high grade glioma 18 | 2,712
pilocytic astrocytoma 18 | 3,086
primitive neuroectodermal tumor 18 | 3,031
subependymal giant cell astrocytoma 18 | 2,287
Carcinoma 17 | 2,147
group 4 medulloblastoma 17 | 1,875
lung adenocarcinoma 17 | 2,713
invasive ductal carcinoma 16 | 2,950
pancreatic cancer 16 | 2,300
Alzheimer's disease 15 | 644
astrocytoma 14 | 1,493
lung carcinoma 14 | 2,844
non-small cell lung cancer 14 | 2,798
adult high grade glioma 13 | 2,148
astrocytic glioma 13 | 2,241
juvenile dermatomyositis 13 | 1,189
ulcerative colitis 13 | 2,087
colon cancer 12 | 1,475
cystic fibrosis 12 | 1,665
dermatomyositis 12 | 933
Rheumatoid Arthritis 11 | 1,160
medulloblastoma 11 | 1,524
Neurodegenerative disease 10 | 383
breast carcinoma 10 | 1,614
ductal carcinoma in situ 10 | 1,745
interstitial cystitis 10 | 2,299
Parkinson's disease 9 | 364
acute quadriplegic myopathy 9 | 1,157
Intellectual disability 8 | 573
Multiple Sclerosis 8 | 498
pituitary cancer 8 | 1,972
spina bifida 8 | 1,064
tuberculosis and treatment for 6 months 8 | 686
Down syndrome 7 | 548
Stomach Neoplasms 7 | 282
Vascular disease 7 | 281
Waldenstrons macroglobulinemia 7 | 765
atypical teratoid/rhabdoid tumor 7 | 1,095
esophageal adenocarcinoma 7 | 737
non primary Sjogren syndrome sicca 7 | 840
pancreatic carcinoma 7 | 567
primary pancreatic ductal adenocarcinoma 7 | 1,271
sonic hedgehog group medulloblastoma 7 | 1,482
ARC syndrome 6 | 14
Juvenile arthritis 6 | 124
Toxic encephalopathy 6 | 131
acute myeloid leukemia 6 | 780
cutaneous lupus erythematosus 6 | 1,056
group 3 medulloblastoma 6 | 2,254
Amyotrophic Lateral Sclerosis 5 | 431
Arthritis 5 | 248
Atopic dermatitis 5 | 944
Dementia 5 | 129
Epilepsy 5 | 346
Hermansky-Pudlak syndrome 5 | 43
Obesity 5 | 616
gastric carcinoma 5 | 832
hereditary spastic paraplegia 5 | 313
posterior fossa group A ependymoma 5 | 1,511
primary Sjogren syndrome 5 | 789
Atherosclerosis 4 | 275
Chediak-Higashi syndrome 4 | 24
Disease Progression 4 | 125
Fatty Liver 4 | 48
IGA Glomerulonephritis 4 | 454
Neoplasm Invasiveness 4 | 127
Osteoporosis 4 | 257
Peripheral Neuropathy 4 | 303
Prostatic Neoplasms 4 | 471
Schizophrenia 4 | 501
active Crohn's disease 4 | 918
adrenocortical carcinoma 4 | 1,427
hepatocellular carcinoma 4 | 532
interstitial lung disease 4 | 291
posterior fossa group B ependymoma 4 | 1,530
progressive supranuclear palsy 4 | 674
aldosterone-producing adenoma 3 | 664
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 499
chronic rhinosinusitis 3 | 512
mucosa-associated lymphoid tissue lymphoma 3 | 480

Tissue

Digestive Tract 115 | 18,473
Nervous System 115 | 18,561
Urinary Tract 115 | 18,444
Blood and immune system 114 | 17,995
Cardiovascular System 114 | 17,958
Endocrine System 114 | 18,512
Female tissues 114 | 18,647
Liver and Pancreas 114 | 18,136
Male tissues 114 | 17,969
Respiratory system 114 | 17,484
Skin and soft tissues 114 | 18,115

Target Family

Non-IDG 71 | 11,971
Enzyme 21 | 4,146
Transporter 11 | 473
Kinase 8 | 634
GPCR 2 | 406
Ion Channel 2 | 341
Transcription Factor 1 | 1,400

GO Component

late endosome 116 | 116
nucleus 5,107 | 5,107
cytoplasm 4,985 | 4,985
plasma membrane 4,118 | 4,118
integral component of membrane 3,679 | 3,679
cytosol 3,265 | 3,265
extracellular exosome 2,758 | 2,758
nucleoplasm 2,717 | 2,717
membrane 1,906 | 1,906
extracellular region 1,493 | 1,493
integral component of plasma m... 1,406 | 1,406
extracellular space 1,304 | 1,304
mitochondrion 1,231 | 1,231
Golgi apparatus 864 | 864
endoplasmic reticulum 859 | 859
endoplasmic reticulum membrane 848 | 848
nucleolus 815 | 815
Golgi membrane 659 | 659
perinuclear region of cytoplas... 611 | 611
cell surface 594 | 594
intracellular 548 | 548
intracellular membrane-bounded... 537 | 537
cell junction 451 | 451
mitochondrial inner membrane 425 | 425
centrosome 409 | 409
focal adhesion 383 | 383
protein complex 355 | 355
cytoskeleton 343 | 343
dendrite 329 | 329
mitochondrial matrix 322 | 322
cell-cell adherens junction 307 | 307
neuronal cell body 303 | 303
microtubule 294 | 294
lysosomal membrane 278 | 278
apical plasma membrane 277 | 277
proteinaceous extracellular ma... 244 | 244
neuron projection 229 | 229
nuclear membrane 218 | 218
early endosome 217 | 217
axon 214 | 214
lysosome 210 | 210
endosome 208 | 208
actin cytoskeleton 205 | 205
external side of plasma membra... 205 | 205
postsynaptic membrane 204 | 204
extracellular matrix 198 | 198
nuclear speck 197 | 197
membrane raft 196 | 196
endoplasmic reticulum lumen 192 | 192
transcription factor complex 184 | 184
endosome membrane 182 | 182
early endosome membrane 180 | 180
basolateral plasma membrane 174 | 174
nuclear chromatin 169 | 169
synapse 166 | 166
cell-cell junction 161 | 161
nuclear envelope 156 | 156
lamellipodium 153 | 153
mitochondrial outer membrane 148 | 148
blood microparticle 147 | 147
myelin sheath 144 | 144
postsynaptic density 144 | 144
cytoplasmic vesicle 143 | 143
microtubule organizing center 137 | 137
cytoplasmic, membrane-bounded ... 132 | 132
ER to Golgi transport vesicle ... 131 | 131
microtubule cytoskeleton 127 | 127
receptor complex 127 | 127
phagocytic vesicle membrane 126 | 126
cytoplasmic vesicle membrane 125 | 125
midbody 125 | 125
trans-Golgi network 124 | 124
cell cortex 119 | 119
cilium 118 | 118
spindle 116 | 116
intracellular ribonucleoprotei... 114 | 114
vesicle 112 | 112
Z disc 110 | 110
bicellular tight junction 110 | 110
anchored component of membrane 109 | 109
growth cone 109 | 109
integral component of lumenal ... 108 | 108
late endosome membrane 107 | 107
endomembrane system 106 | 106
centriole 105 | 105
recycling endosome 104 | 104
spindle pole 104 | 104
perikaryon 103 | 103
integral component of endoplas... 101 | 101
intermediate filament 101 | 101
melanosome 101 | 101
chromosome 100 | 100
dendritic spine 99 | 99
ubiquitin ligase complex 99 | 99
peroxisome 98 | 98
nuclear matrix 97 | 97
PML body 94 | 94
Golgi lumen 93 | 93
keratin filament 93 | 93
trans-Golgi network membrane 92 | 92

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 2 NMNAT2 Tbio Enzyme -1.43192 31.0 94
Potassium voltage-gated channel subfamily KQT member 1 KCNQ1 Tclin Ion Channel -2.92762 876.7 339
Ankyrin repeat domain-containing protein 13D ANKRD13D Tdark Non-IDG 0.00000 36
Ras-related protein Rab-14 RAB14 Tbio Enzyme -1.40555 28.2 91
Ras-related protein Rab-27A RAB27A Tbio Enzyme -2.22946 184.9 247
Serotransferrin TF Tchem Non-IDG -4.13136 13124.3 952
Ras-related protein Rab-9A RAB9A Tchem Enzyme -0.85649 7.48 172
Ras-related protein Rab-7a RAB7A Tbio Enzyme -2.60609 403.7 216
H(+)/Cl(-) exchange transporter 3 CLCN3 Tchem Ion Channel -2.24361 194.9 155
Lysosome-associated membrane glycoprotein 2 LAMP2 Tbio Non-IDG -2.51989 315.7 757