Development Level

Tbio 88 | 11,651
Tchem 13 | 1,388
Tclin 9 | 612
Tdark 9 | 6,593

IMPC Phenotype

preweaning lethality, complete... 9 | 979
decreased body weight 5 | 161
abnormal behavior 3 | 298
abnormal embryo size 2 | 220
decreased circulating HDL chol... 2 | 68
decreased circulating aspartat... 2 | 34
decreased circulating choleste... 2 | 93
decreased circulating lactate ... 2 | 3
decreased grip strength 2 | 116
decreased mean corpuscular hem... 2 | 50
embryonic lethality prior to o... 2 | 239
increased body weight 2 | 25
increased total body fat amoun... 2 | 134
short tibia 2 | 97
abnormal body wall morphology 1 | 9
abnormal femur morphology 1 | 14
abnormal gait 1 | 69
abnormal kidney morphology 1 | 65
abnormal motor capabilities-co... 1 | 5
abnormal response to new envir... 1 | 10
abnormal response to tactile s... 1 | 17
abnormal skin morphology 1 | 50
abnormal thoracic cage shape 1 | 3
abnormal thymus morphology 1 | 7
alopecia 1 | 1
decreased IgE level 1 | 6
decreased blood urea nitrogen ... 1 | 51
decreased bone mineral density 1 | 126
decreased circulating alkaline... 1 | 46
decreased circulating bilirubi... 1 | 19
decreased circulating creatini... 1 | 39
decreased circulating glucose ... 1 | 126
decreased circulating unsatura... 1 | 2
decreased large unstained cell... 1 | 11
decreased lean body mass 1 | 135
decreased leukocyte cell numbe... 1 | 73
decreased total body fat amoun... 1 | 207
decreased total retina thickne... 1 | 17
decreased vertical activity 1 | 208
embryonic growth retardation 1 | 106
embryonic lethality prior to t... 1 | 278
enlarged spleen 1 | 41
hyperactivity 1 | 148
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
increased body length 1 | 32
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating choleste... 1 | 66
increased circulating glucose ... 1 | 24
increased circulating iron lev... 1 | 30
increased circulating serum al... 1 | 22
increased circulating total pr... 1 | 28
increased circulating triglyce... 1 | 42
increased fasted circulating g... 1 | 76
increased heart weight 1 | 62
increased hemoglobin content 1 | 45
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased neutrophil cell numb... 1 | 46
mammalian phenotype 1 | 17
preweaning lethality, incomple... 1 | 499
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
protruding tongue 1 | 3
small thymus 1 | 16
thrombocytosis 1 | 27
tremors 1 | 39
trunk curl 1 | 16

Disease

ovarian cancer 74 | 8,520
Carcinoma 72 | 11,493
osteosarcoma 62 | 7,950
psoriasis 47 | 6,694
medulloblastoma, large-cell 46 | 6,241
glioblastoma 43 | 5,792
lung cancer 38 | 4,740
atypical teratoid / rhabdoid tumor 36 | 5,112
ependymoma 28 | 4,679
malignant mesothelioma 27 | 3,232
Breast cancer 24 | 3,578
Cancer 24 | 2,499
adult high grade glioma 22 | 3,801
pancreatic ductal adenocarcinoma liver metastasis 22 | 1,962
tuberculosis 22 | 2,010
intraductal papillary-mucinous adenoma (IPMA) 21 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 21 | 2,989
Multiple myeloma 20 | 1,332
intraductal papillary-mucinous neoplasm (IPMN) 20 | 3,291
oligodendroglioma 20 | 2,850
Kidney cancer 19 | 2,613
diabetes mellitus 19 | 1,728
Astrocytoma, Pilocytic 18 | 3,081
group 4 medulloblastoma 18 | 1,855
primitive neuroectodermal tumor 18 | 3,035
Pick disease 17 | 1,894
lung adenocarcinoma 17 | 2,716
pancreatic cancer 17 | 2,398
subependymal giant cell astrocytoma 17 | 2,287
group 3 medulloblastoma 16 | 4,104
invasive ductal carcinoma 16 | 2,951
Autosomal recessive predisposition 15 | 1,442
Intellectual disability 15 | 1,016
astrocytic glioma 15 | 2,597
Neurodegenerative disease 14 | 414
lung carcinoma 14 | 2,843
juvenile dermatomyositis 13 | 1,187
non-small cell lung cancer 13 | 2,890
Alzheimer's disease 12 | 658
colon cancer 12 | 1,478
Epilepsy 11 | 792
Rheumatoid arthritis 11 | 1,191
Schizophrenia 11 | 1,160
astrocytoma 11 | 1,146
breast carcinoma 11 | 1,638
cystic fibrosis 11 | 1,696
dermatomyositis 11 | 966
ulcerative colitis 11 | 1,819
acute quadriplegic myopathy 10 | 1,158
ductal carcinoma in situ 10 | 1,745
interstitial cystitis 10 | 2,312
Dull intelligence 8 | 645
Low intelligence 8 | 645
Mental Retardation 8 | 645
Mental deficiency 8 | 645
Multiple Sclerosis 8 | 540
Parkinson's disease 8 | 392
Poor school performance 8 | 645
Stomach Neoplasms 8 | 300
pediatric high grade glioma 8 | 1,064
pituitary cancer 8 | 1,972
spina bifida 8 | 1,074
Cognitive delay 7 | 608
Down syndrome 7 | 499
Global developmental delay 7 | 608
Mental and motor retardation 7 | 608
Muscle hypotonia 7 | 571
Seizures 7 | 596
Short stature 7 | 531
Vascular disease 7 | 319
Waldenstrons macroglobulinemia 7 | 765
esophageal adenocarcinoma 7 | 737
hereditary spastic paraplegia 7 | 318
non primary Sjogren syndrome sicca 7 | 891
pancreatic carcinoma 7 | 562
primary pancreatic ductal adenocarcinoma 7 | 1,109
ARC syndrome 6 | 13
Arthritis 6 | 290
Arthritis, Juvenile 6 | 126
Breast Neoplasms 6 | 445
Cerebral atrophy 6 | 178
Dementia 6 | 175
Disease Models, Animal 6 | 155
Juvenile arthritis 6 | 126
Neoplasm Invasiveness 6 | 161
Osteoporosis 6 | 363
Toxic encephalopathy 6 | 141
acute myeloid leukemia 6 | 783
Acquired scoliosis 5 | 281
Atopic dermatitis 5 | 952
Bipolar Disorder 5 | 666
Byzanthine arch palate 5 | 194
Curvature of spine 5 | 282
Depressive disorder 5 | 409
Failure to gain weight 5 | 365
Long face 5 | 71
Mental Depression 5 | 333
cutaneous lupus erythematosus 5 | 1,057
hepatocellular carcinoma 5 | 547
primary Sjogren syndrome 5 | 735

Tissue

Blood and immune system 116 | 16,909
Digestive Tract 116 | 17,369
Endocrine System 116 | 18,159
Female tissues 116 | 17,400
Male tissues 116 | 17,142
Nervous System 116 | 16,725
Respiratory system 116 | 16,393
Skin and soft tissues 116 | 17,230
Liver and Pancreas 115 | 16,750
Urinary Tract 115 | 16,678
Cardiovascular System 114 | 15,192

Target Family

Non-IDG 73 | 12,091
Enzyme 21 | 4,145
Transporter 11 | 473
Kinase 8 | 634
Ion Channel 3 | 344
GPCR 2 | 408
Transcription Factor 1 | 1,400

GO Component

late endosome 119 | 119
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Ras-related protein Rab-22A RAB22A Tbio Enzyme -1.40824 19.7 123
Kinase D-interacting substrate of 220 kDa KIDINS220 Tbio Enzyme -2.42897 262.3 191
Vacuolar protein sorting-associated protein 35 VPS35 Tbio Non-IDG -2.02621 104.1 124
Sequestosome-1 SQSTM1 Tbio Non-IDG -2.78728 635.1 766
WASH complex subunit 1 WASHC1 Tbio Non-IDG -0.28297 2.17 4
Ras-GEF domain-containing family member 1B RASGEF1B Tdark Non-IDG -0.73083 5.52 49
Vacuolar protein sorting-associated protein 4A VPS4A Tbio Non-IDG -1.69610 49.5 94
Lysosome-associated membrane glycoprotein 2 LAMP2 Tbio Non-IDG -2.57929 343.7 905
Ras-related protein Rab-9A RAB9A Tbio Enzyme -0.89163 7.82 177
Ras-related protein Rab-27A RAB27A Tbio Enzyme -2.30319 204.9 308