Development Level

Tbio 136 | 11,445
Tchem 20 | 1,598
Tclin 6 | 613
Tdark 6 | 6,588

Collection

Kinase: IDG Consortium (Target... 3 | 125
RFA-RM-18-021 3 | 328
Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

preweaning lethality, complete... 12 | 979
preweaning lethality, incomple... 9 | 499
abnormal behavior 5 | 298
abnormal retina morphology 4 | 71
increased body weight 4 | 25
abnormal bone mineralization 3 | 38
abnormal bone structure 3 | 187
abnormal embryo size 3 | 220
decreased circulating insulin ... 3 | 76
decreased circulating iron lev... 3 | 32
decreased total body fat amoun... 3 | 207
decreased vertical activity 3 | 208
embryonic lethality prior to o... 3 | 239
embryonic lethality prior to t... 3 | 278
hyperactivity 3 | 148
increased circulating calcium ... 3 | 34
increased lean body mass 3 | 172
increased or absent threshold ... 3 | 101
prenatal lethality prior to he... 3 | 87
abnormal coat-hair pigmentatio... 2 | 64
abnormal cornea morphology 2 | 31
abnormal eye morphology 2 | 68
abnormal pericardium morpholog... 2 | 26
abnormal placenta size 2 | 20
abnormal stomach morphology 2 | 10
cardiovascular system phenotyp... 2 | 36
decreased bone mineral content 2 | 151
decreased bone mineral density 2 | 126
decreased circulating choleste... 2 | 93
decreased circulating creatini... 2 | 39
decreased circulating glucose ... 2 | 126
decreased lymphocyte cell numb... 2 | 83
decreased threshold for audito... 2 | 26
edema 2 | 59
embryonic growth retardation 2 | 106
hypoactivity 2 | 132
impaired glucose tolerance 2 | 75
impaired pupillary reflex 2 | 26
improved glucose tolerance 2 | 79
increased bone mineral density 2 | 72
increased circulating alkaline... 2 | 122
increased grip strength 2 | 41
increased mean corpuscular vol... 2 | 92
increased monocyte cell number 2 | 63
increased startle reflex 2 | 112
increased total body fat amoun... 2 | 134
abnormal behavioral response t... 1 | 66
abnormal craniofacial morpholo... 1 | 33
abnormal head morphology 1 | 10
abnormal iris morphology 1 | 13
abnormal locomotor behavior 1 | 24
abnormal neural tube closure 1 | 46
abnormal retinal inner nuclear... 1 | 8
abnormal seminal vesicle morph... 1 | 114
abnormal skin coloration 1 | 25
abnormal sleep behavior 1 | 70
abnormal startle reflex 1 | 15
abnormal vibrissa morphology 1 | 25
absent startle reflex 1 | 24
absent vibrissae 1 | 12
cataract 1 | 92
corneal opacity 1 | 32
decreased T cell number 1 | 15
decreased blood urea nitrogen ... 1 | 51
decreased body length 1 | 101
decreased caudal vertebrae num... 1 | 53
decreased circulating HDL chol... 1 | 68
decreased circulating chloride... 1 | 30
decreased circulating potassiu... 1 | 20
decreased circulating serum al... 1 | 82
decreased eosinophil cell numb... 1 | 24
decreased heart rate variabili... 1 | 13
decreased hematocrit 1 | 46
decreased lean body mass 1 | 135
decreased mature B cell number 1 | 7
decreased neutrophil cell numb... 1 | 42
decreased prepulse inhibition 1 | 82
enlarged lymph nodes 1 | 37
female infertility 1 | 60
hemorrhage 1 | 23
increased blood urea nitrogen ... 1 | 48
increased bone mineral content 1 | 108
increased circulating glucose ... 1 | 24
increased circulating iron lev... 1 | 30
increased circulating phosphat... 1 | 26
increased circulating serum al... 1 | 22
increased circulating total pr... 1 | 28
increased circulating triglyce... 1 | 42
increased coping response 1 | 4
increased exploration in new e... 1 | 8
increased heart rate 1 | 23
increased heart rate variabili... 1 | 7
increased heart weight 1 | 62
increased prepulse inhibition 1 | 32
increased vertical activity 1 | 24
persistence of hyaloid vascula... 1 | 33
shortened PQ interval 1 | 7
shortened PR interval 1 | 6
shortened ST segment 1 | 10
small testis 1 | 58

Disease

Carcinoma 131 | 11,493
ovarian cancer 109 | 8,520
osteosarcoma 95 | 7,950
glioblastoma 80 | 5,792
medulloblastoma, large-cell 80 | 6,241
psoriasis 73 | 6,694
atypical teratoid / rhabdoid tumor 65 | 5,112
ependymoma 60 | 4,679
Breast cancer 56 | 3,578
lung cancer 54 | 4,740
adult high grade glioma 49 | 3,801
intraductal papillary-mucinous adenoma (IPMA) 49 | 2,955
invasive ductal carcinoma 49 | 2,951
Kidney cancer 47 | 2,613
lung carcinoma 46 | 2,843
intraductal papillary-mucinous carcinoma (IPMC) 45 | 2,989
Cancer 44 | 2,499
group 3 medulloblastoma 43 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 42 | 3,291
Astrocytoma, Pilocytic 41 | 3,081
non-small cell lung cancer 40 | 2,890
pancreatic cancer 40 | 2,398
malignant mesothelioma 38 | 3,232
subependymal giant cell astrocytoma 37 | 2,287
interstitial cystitis 35 | 2,312
oligodendroglioma 35 | 2,850
group 4 medulloblastoma 33 | 1,855
lung adenocarcinoma 33 | 2,716
primitive neuroectodermal tumor 33 | 3,035
tuberculosis 32 | 2,010
astrocytic glioma 30 | 2,597
breast carcinoma 30 | 1,638
ulcerative colitis 29 | 1,819
ductal carcinoma in situ 27 | 1,745
primary pancreatic ductal adenocarcinoma 27 | 1,109
cystic fibrosis 26 | 1,696
Pick disease 24 | 1,894
pancreatic ductal adenocarcinoma liver metastasis 22 | 1,962
astrocytoma 21 | 1,146
adrenocortical carcinoma 20 | 1,428
juvenile dermatomyositis 20 | 1,187
spina bifida 20 | 1,074
Intellectual disability 19 | 1,016
colon cancer 19 | 1,478
pituitary cancer 19 | 1,972
diabetes mellitus 18 | 1,728
Autosomal recessive predisposition 17 | 1,442
autosomal dominant Emery-Dreifuss muscular dystrophy 17 | 510
Liver Cirrhosis, Experimental 15 | 769
Rheumatoid arthritis 15 | 1,191
Schizophrenia 15 | 1,160
acute quadriplegic myopathy 15 | 1,158
dermatomyositis 15 | 966
gastric carcinoma 15 | 807
Waldenstrons macroglobulinemia 14 | 765
pediatric high grade glioma 14 | 1,064
medulloblastoma 13 | 720
Alzheimer's disease 12 | 658
Duchenne muscular dystrophy 12 | 601
Multiple myeloma 12 | 1,332
Dull intelligence 11 | 645
Liver cancer 11 | 604
Low intelligence 11 | 645
Mental Retardation 11 | 645
Mental deficiency 11 | 645
Poor school performance 11 | 645
mucosa-associated lymphoid tissue lymphoma 11 | 484
Kidney disease 10 | 430
Melanoma 10 | 711
Neurodegenerative disease 10 | 414
active ulcerative colitis 10 | 764
cutaneous lupus erythematosus 10 | 1,057
esophageal adenocarcinoma 10 | 737
Breast Neoplasms 9 | 445
Endometrial cancer 9 | 311
Muscle hypotonia 9 | 571
Neoplasm Invasiveness 9 | 161
Neoplasm Metastasis 9 | 168
Skin cancer 9 | 469
nasopharyngeal carcinoma 9 | 1,058
non primary Sjogren syndrome sicca 9 | 891
pancreatic carcinoma 9 | 562
primary Sjogren syndrome 9 | 735
sonic hedgehog group medulloblastoma 9 | 467
Bipolar Disorder 8 | 666
Cognitive delay 8 | 608
Down syndrome 8 | 499
Endometriosis 8 | 540
Global developmental delay 8 | 608
Mammary Neoplasms 8 | 425
Mental and motor retardation 8 | 608
Obesity 8 | 678
Stomach Neoplasms 8 | 300
active Crohn's disease 8 | 922
aldosterone-producing adenoma 8 | 665
interstitial lung disease 8 | 298
Epilepsy 7 | 792
acute myeloid leukemia 7 | 783
gastric cancer 7 | 459
hepatocellular carcinoma 7 | 547

Tissue

Digestive Tract 164 | 17,369
Endocrine System 164 | 18,159
Female tissues 164 | 17,400
Liver and Pancreas 164 | 16,750
Blood and immune system 163 | 16,909
Male tissues 163 | 17,142
Respiratory system 163 | 16,393
Urinary Tract 163 | 16,678
Skin and soft tissues 162 | 17,230
Nervous System 161 | 16,725
Cardiovascular System 158 | 15,192

Target Family

Non-IDG 122 | 12,091
Enzyme 24 | 4,145
Kinase 17 | 634
Ion Channel 3 | 344
Transporter 2 | 473

GO Component

lamellipodium 168 | 168
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Potassium voltage-gated channel subfamily A member 2 KCNA2 Tclin Ion Channel -2.55550 343.3 205
Rab-3A-interacting protein RAB3IP Tbio Non-IDG -1.03500 11.6 89
Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 ARAP3 Tbio Non-IDG -0.96067 13.8 85
Palladin PALLD Tbio Non-IDG -2.73002 528.8 164
Ras GTPase-activating-like protein IQGAP2 IQGAP2 Tbio Enzyme -1.40687 25.2 146
Unconventional myosin-X MYO10 Tbio Non-IDG -1.49855 36.4 47
Polycystin-2 PKD2 Tchem Ion Channel -2.63806 461.3 231
Coronin-1B CORO1B Tbio Non-IDG -1.09320 13.6 149
Calcium and integrin-binding protein 1 CIB1 Tbio Non-IDG -2.08897 121.1 264
Plexin-D1 PLXND1 Tbio Non-IDG -1.64721 46.3 171