Development Level

Tdark 62 | 6,593
Tbio 32 | 11,651
Tchem 1 | 1,388

IMPC Phenotype

preweaning lethality, incomple... 2 | 499
abnormal kidney morphology 1 | 65
decreased CD4-positive, alpha ... 1 | 7
decreased CD8-positive, alpha-... 1 | 8
decreased T cell number 1 | 15
decreased circulating HDL chol... 1 | 68
decreased circulating calcium ... 1 | 36
decreased circulating free fat... 1 | 31
embryonic lethality prior to t... 1 | 278
increased IgG2b level 1 | 1
increased circulating HDL chol... 1 | 80
increased circulating choleste... 1 | 66
increased mean corpuscular vol... 1 | 92
prenatal lethality prior to he... 1 | 87
preweaning lethality, complete... 1 | 979

Disease

psoriasis 74 | 6,694
Carcinoma 42 | 11,493
diabetes mellitus 34 | 1,728
Atopic dermatitis 27 | 952
ovarian cancer 19 | 8,520
osteosarcoma 13 | 7,950
Cancer 10 | 2,499
medulloblastoma, large-cell 10 | 6,241
non-small cell lung cancer 10 | 2,890
Dystrophia unguium 9 | 53
Monilethrix 9 | 18
cystic fibrosis 9 | 1,696
nasopharyngeal carcinoma 8 | 1,058
spina bifida 8 | 1,074
Palmoplantar keratosis 7 | 74
ductal carcinoma in situ 7 | 1,745
esophageal adenocarcinoma 7 | 737
lung cancer 7 | 4,740
Breast cancer 6 | 3,578
Hereditary mucosal leukokeratosis 6 | 7
Hypotrichosis 6 | 47
Nail Diseases 6 | 24
Nail abnormality 6 | 22
Pachyonychia congenita 6 | 10
adult high grade glioma 6 | 3,801
Abnormal blistering of the skin 5 | 54
Abnormality of metabolism/homeostasis 5 | 134
Alopecia 5 | 115
Blister of skin 5 | 54
Breast Neoplasms 5 | 445
Highly variable severity 5 | 157
Hyperhidrosis disorder 5 | 81
Increased sweating 5 | 81
Leukokeratosis 5 | 19
Leukoplakia, Oral 5 | 20
Mammary Neoplasms 5 | 425
Nail dysplasia 5 | 52
Papilloma 5 | 44
Skin bulla 5 | 54
Sweating 5 | 81
Variable expressivity 5 | 157
breast carcinoma 5 | 1,638
interstitial cystitis 5 | 2,312
malignant mesothelioma 5 | 3,232
Brittle hair 4 | 25
Fractured hair 4 | 25
Fragile hair 4 | 25
Keratosis 4 | 37
Kidney cancer 4 | 2,613
Onychogryposis 4 | 13
Reduced tensile strength of hair 4 | 25
lung adenocarcinoma 4 | 2,716
pancreatic cancer 4 | 2,398
Abnormal eyelashes 3 | 13
Ameloblastoma 3 | 24
Anemia 3 | 365
Autosomal recessive predisposition 3 | 1,442
Carcinoma, Squamous Cell 3 | 110
Congenital ichthyosiform erythroderma 3 | 28
Dental caries 3 | 164
Epidermolysis bullosa simplex 3 | 9
Epidermolytic hyperkeratosis 3 | 14
Eyebrow abnormalities 3 | 12
Fine hair 3 | 42
Ichthyoses 3 | 41
Infantile onset 3 | 238
Liver disease 3 | 237
Patchy alopecia 3 | 5
Perifollicular hyperkeratosis 3 | 4
Phrynoderma 3 | 11
Recurrent skin infections 3 | 21
Rotting teeth 3 | 73
Slow-growing hair 3 | 19
Squamous cell carcinoma 3 | 129
Syringoma 3 | 11
active ulcerative colitis 3 | 764
atypical teratoid / rhabdoid tumor 3 | 5,112
cutaneous lupus erythematosus 3 | 1,057
Abnormal respiratory patterns 2 | 20
Animal Mammary Neoplasms 2 | 136
Atrophic scar 2 | 18
Carcinoma, Renal Cell 2 | 124
Ecchymosis 2 | 66
Epidermolysis bullosa 2 | 21
Erythema 2 | 58
Esophageal Squamous Cell Carcinoma 2 | 77
Flushing 2 | 60
Increased tendency to bruise 2 | 66
Mammary Neoplasms, Animal 2 | 136
Mammary Neoplasms, Experimental 2 | 154
Milium Cyst 2 | 16
Pleomorphic adenoma 2 | 18
Renal Cell Carcinoma 2 | 214
Ridged nails 2 | 14
Skin disease 2 | 66
Squamous cell carcinoma of esophagus 2 | 77
Woolly hair, autosomal dominant 2 | 5
Woolly hair, congenital 2 | 5
Wooly hair 2 | 17
hypopigmented skin patch 2 | 59

Tissue

Female tissues 41 | 17,400
Skin and soft tissues 39 | 17,230
Digestive Tract 34 | 17,369
Endocrine System 34 | 18,159
Blood and immune system 32 | 16,909
Male tissues 28 | 17,142
Liver and Pancreas 23 | 16,750
Nervous System 23 | 16,725
Respiratory system 22 | 16,393
Urinary Tract 20 | 16,678
Cardiovascular System 13 | 15,192

Target Family

Non-IDG 93 | 12,091
Enzyme 1 | 4,145
GPCR 1 | 408

GO Component

keratin filament 95 | 95
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Keratin, type II cytoskeletal 6C KRT6C Tbio Non-IDG -0.47272 2.11 89
Keratin-associated protein 10-2 KRTAP10-2 Tdark Non-IDG 0.00000 5
Keratin-associated protein 10-3 KRTAP10-3 Tdark Non-IDG 1.08 0.05 0
Keratin-associated protein 10-1 KRTAP10-1 Tdark Non-IDG 0.48 0.20 0
Keratin-associated protein 10-6 KRTAP10-6 Tdark Non-IDG 0.00000 1
Keratin-associated protein 10-5 KRTAP10-5 Tdark Non-IDG 0.60 0.11 0
Keratin-associated protein 10-4 KRTAP10-4 Tdark Non-IDG 0.60 0.25 0
Keratin-associated protein 12-4 KRTAP12-4 Tdark Non-IDG 0.00000 0
Keratin-associated protein 12-3 KRTAP12-3 Tdark Non-IDG 1.23 0.05 0
Keratin, type I cytoskeletal 13 KRT13 Tbio Non-IDG -2.25522 171.2 403