Development Level

Tdark 5 | 6,588
Tbio 1 | 11,445
Tclin 1 | 613

IMPC Phenotype

abnormal eye morphology 1 | 68
abnormal lung morphology 1 | 26
abnormal seminal vesicle morph... 1 | 114
anophthalmia 1 | 33
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased mean corpuscular hem... 1 | 50
edema 1 | 59
enlarged lung 1 | 2
increased anti-nuclear antigen... 1 | 19
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
prenatal lethality prior to he... 1 | 87
preweaning lethality, complete... 1 | 979

Disease

Carcinoma 7 | 11,493
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
osteosarcoma 4 | 7,950
astrocytic glioma 3 | 2,597
medulloblastoma, large-cell 3 | 6,241
oligodendroglioma 3 | 2,850
ovarian cancer 3 | 8,520
Agammaglobulinemia 2 | 34
adrenocortical carcinoma 2 | 1,428
atypical teratoid / rhabdoid tumor 2 | 5,112
ductal carcinoma in situ 2 | 1,745
ependymoma 2 | 4,679
group 3 medulloblastoma 2 | 4,104
interstitial cystitis 2 | 2,312
invasive ductal carcinoma 2 | 2,951
lung adenocarcinoma 2 | 2,716
lung cancer 2 | 4,740
primary pancreatic ductal adenocarcinoma 2 | 1,109
psoriasis 2 | 6,694
tuberculosis 2 | 2,010
AGAMMAGLOBULINEMIA 1, AUTOSOMAL RECESSIVE 1 | 8
ATRIAL FIBRILLATION, FAMILIAL, 1 (disorder) 1 | 21
Adenocarcinoma 1 | 122
Advanced bone age 1 | 35
Agammaglobulinemia, non-Bruton type 1 | 8
Astrocytoma, Pilocytic 1 | 3,081
Atrial Fibrillation 1 | 124
Atrial Fibrillation, Familial, 3 1 | 2
Atrioventricular block 1 | 35
Brugada syndrome 1 | 29
Cardiac Arrhythmia 1 | 103
Cardiac arrest 1 | 36
Cardiomegaly 1 | 116
Cardiomyopathies 1 | 110
Cardiomyopathy 1 | 116
Catecholaminergic polymorphic ventricular tachycardia 1 | 12
Celiac disease 1 | 116
Coarse facial features 1 | 108
Congenital sensorineural hearing loss 1 | 12
Diabetes Mellitus, Non-Insulin-Dependent 1 | 145
Diabetes Mellitus, Type 2 1 | 142
Diastasis recti 1 | 9
Eaton-Lambert syndrome 1 | 40
Elevated heart rate 1 | 25
Epidermodysplasia verruciformis 1 | 21
Epilepsy 1 | 792
Exophthalmos 1 | 112
Familial atrial fibrillation 1 | 23
Fetal overgrowth 1 | 16
Generalized overgrowth 1 | 16
Gestational diabetes 1 | 26
Gonadoblastoma 1 | 34
Hearing Loss, Noise-Induced 1 | 5
Heart conduction disease 1 | 83
Hepatoblastoma 1 | 19
Hepatomegaly 1 | 285
Intestinal Neoplasms 1 | 12
Jervell-Lange Nielsen syndrome 1 | 4
Large bregma sutures 1 | 46
Large fontanelle 1 | 46
Large, late-closing fontanelle 1 | 46
Long QT syndrome 1 | 39
Long QT syndrome 1 1 | 20
Macroglossia 1 | 65
Multiple Sclerosis 1 | 540
Neonatal hypoglycemia 1 | 17
Nephroblastoma 1 | 51
Noise-induced hearing loss 1 | 5
Overgrowth 1 | 16
Panic disorder 1 | 61
Pick disease 1 | 1,894
Prolonged QT interval 1 | 15
Prominent back of the head 1 | 21
Prominent eyes 1 | 96
Prominent globes 1 | 96
Prominent occiput 1 | 21
Protruding eyes 1 | 96
Romano-Ward Syndrome 1 | 12
Sensorineural hearing loss 1 | 106
Short QT syndrome 1 | 12
Sudden Cardiac Death 1 | 29
Sudden infant death syndrome 1 | 32
Syncope 1 | 22
Tachycardia 1 | 43
Thickened facial skin with coarse facial features 1 | 108
Timothy syndrome 1 | 11
Torsades de Pointes 1 | 8
Type 2 diabetes mellitus 1 | 272
Ventricular Fibrillation 1 | 17
Wide bregma sutures 1 | 46
adult high grade glioma 1 | 3,801
cystic fibrosis 1 | 1,696
diabetes mellitus 1 | 1,728
esophageal adenocarcinoma 1 | 737
gastric carcinoma 1 | 807
intraductal papillary-mucinous adenoma (IPMA) 1 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 1 | 2,989
non-small cell lung cancer 1 | 2,890
sarcoidosis 1 | 370
spina bifida 1 | 1,074

Tissue

Blood and immune system 7 | 16,909
Digestive Tract 7 | 17,369
Endocrine System 7 | 18,159
Female tissues 7 | 17,400
Male tissues 7 | 17,142
Nervous System 7 | 16,725
Respiratory system 7 | 16,393
Cardiovascular System 6 | 15,192
Liver and Pancreas 6 | 16,750
Skin and soft tissues 6 | 17,230
Urinary Tract 6 | 16,678

Target Family

Non-IDG 6 | 12,091
Ion Channel 1 | 344

GO Component

ion channel complex 7 | 7
nucleus 5,097 | 5,097
cytosol 4,834 | 4,834
plasma membrane 4,414 | 4,414
cytoplasm 4,094 | 4,094
integral component of membrane 3,665 | 3,665
nucleoplasm 2,996 | 2,996
extracellular exosome 2,767 | 2,767
membrane 1,917 | 1,917
extracellular region 1,833 | 1,833
integral component of plasma m... 1,418 | 1,418
extracellular space 1,380 | 1,380
mitochondrion 1,281 | 1,281
endoplasmic reticulum 938 | 938
Golgi apparatus 904 | 904
endoplasmic reticulum membrane 879 | 879
nucleolus 824 | 824
Golgi membrane 676 | 676
perinuclear region of cytoplas... 644 | 644
cell surface 608 | 608
intracellular membrane-bounded... 593 | 593
intracellular 566 | 566
protein complex 552 | 552
cell junction 502 | 502
mitochondrial inner membrane 432 | 432
centrosome 427 | 427
focal adhesion 387 | 387
nuclear speck 371 | 371
mitochondrial matrix 354 | 354
cytoskeleton 352 | 352
dendrite 330 | 330
neuronal cell body 325 | 325
lysosomal membrane 301 | 301
microtubule 298 | 298
apical plasma membrane 292 | 292
endoplasmic reticulum lumen 291 | 291
extracellular matrix 267 | 267
proteinaceous extracellular ma... 267 | 267
nuclear body 266 | 266
axon 250 | 250
external side of plasma membra... 247 | 247
endosome 239 | 239
nuclear membrane 239 | 239
neuron projection 235 | 235
early endosome 234 | 234
lysosome 222 | 222
cytoplasmic vesicle 217 | 217
membrane raft 215 | 215
postsynaptic membrane 210 | 210
early endosome membrane 203 | 203
postsynaptic density 202 | 202
endosome membrane 197 | 197
actin cytoskeleton 196 | 196
basolateral plasma membrane 184 | 184
nuclear chromatin 184 | 184
blood microparticle 175 | 175
synapse 172 | 172
transcription factor complex 172 | 172
cilium 171 | 171
lamellipodium 168 | 168
mitochondrial outer membrane 163 | 163
nuclear envelope 160 | 160
microtubule organizing center 153 | 153
cell-cell junction 149 | 149
myelin sheath 144 | 144
midbody 141 | 141
phagocytic vesicle membrane 138 | 138
recycling endosome membrane 138 | 138
microtubule cytoskeleton 134 | 134
vesicle 134 | 134
cytoplasmic vesicle membrane 133 | 133
ER to Golgi transport vesicle ... 132 | 132
receptor complex 132 | 132
trans-Golgi network 131 | 131
fibrillar center 128 | 128
centriole 124 | 124
ficolin-1-rich granule lumen 124 | 124
late endosome membrane 122 | 122
intracellular ribonucleoprotei... 121 | 121
Z disc 119 | 119
bicellular tight junction 119 | 119
late endosome 119 | 119
cell cortex 118 | 118
dendritic spine 118 | 118
growth cone 116 | 116
secretory granule lumen 116 | 116
spindle 116 | 116
spindle pole 115 | 115
chromosome 114 | 114
perikaryon 114 | 114
recycling endosome 109 | 109
anchored component of membrane 108 | 108
endomembrane system 108 | 108
integral component of lumenal ... 108 | 108
ciliary basal body 105 | 105
nuclear matrix 105 | 105
integral component of endoplas... 103 | 103
secretory granule membrane 103 | 103
Golgi lumen 101 | 101
melanosome 101 | 101
ubiquitin ligase complex 100 | 100

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