Development Level

Tbio 88 | 10,625
Tchem 18 | 1,890
Tdark 7 | 7,003
Tclin 1 | 602

Collection

Eligible Kinase Proteins 1 | 134

IMPC Term

preweaning lethality, complete... 7 | 633
preweaning lethality, incomple... 3 | 260
abnormal behavior 2 | 226
abnormal retina morphology 2 | 100
abnormal retinal pigmentation 2 | 61
decreased body length 2 | 108
embryonic lethality prior to o... 2 | 148
increased mean corpuscular vol... 2 | 91
abnormal bone structure 1 | 131
abnormal cranium morphology 1 | 32
abnormal embryo size 1 | 112
abnormal forebrain development 1 | 18
abnormal hindbrain development 1 | 24
abnormal lung morphology 1 | 15
abnormal midbrain development 1 | 22
abnormal neural tube closure 1 | 37
abnormal sacral vertebrae morp... 1 | 5
abnormal spinal cord morpholog... 1 | 8
abnormal spine curvature 1 | 7
abnormal spleen morphology 1 | 36
abnormal vocalization 1 | 21
decreased KLRG1-positive NK ce... 1 | 9
decreased body weight 1 | 174
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 49
decreased circulating HDL chol... 1 | 77
decreased circulating choleste... 1 | 85
decreased circulating free fat... 1 | 39
decreased eosinophil cell numb... 1 | 41
decreased lean body mass 1 | 195
decreased leukocyte cell numbe... 1 | 54
decreased lymphocyte cell numb... 1 | 9
decreased neutrophil cell numb... 1 | 37
embryonic lethality prior to t... 1 | 187
hyperactivity 1 | 108
increased NK cell number 1 | 19
increased bone mineral content 1 | 92
increased circulating alkaline... 1 | 119
increased circulating potassiu... 1 | 31
increased exploration in new e... 1 | 56
increased grip strength 1 | 83
increased mean corpuscular hem... 1 | 93
increased startle reflex 1 | 38
prenatal lethality prior to he... 1 | 64
small kidney 1 | 10
small superior vagus ganglion 1 | 20
thick ventricular wall 1 | 7

Disease

ovarian cancer 65 | 8,484
osteosarcoma 51 | 7,933
medulloblastoma, large-cell 49 | 6,234
lung cancer 46 | 4,466
psoriasis 37 | 6,685
glioblastoma 36 | 5,572
atypical teratoid / rhabdoid tumor 32 | 4,369
Multiple myeloma 30 | 1,327
oligodendroglioma 29 | 2,849
intraductal papillary-mucinous neoplasm (IPMN) 28 | 3,289
acute quadriplegic myopathy 27 | 1,157
ependymoma 27 | 2,514
primitive neuroectodermal tumor 25 | 3,031
Cancer 24 | 2,346
Waldenstrons macroglobulinemia 24 | 765
group 3 medulloblastoma 24 | 2,254
intraductal papillary-mucinous carcinoma (IPMC) 24 | 2,988
astrocytoma 22 | 1,493
Pick disease 21 | 1,893
lung adenocarcinoma 21 | 2,713
Breast cancer 20 | 3,094
non-small cell lung cancer 19 | 2,798
intraductal papillary-mucinous adenoma (IPMA) 17 | 2,956
subependymal giant cell astrocytoma 17 | 2,287
dermatomyositis 16 | 933
malignant mesothelioma 16 | 3,162
diabetes mellitus 15 | 1,663
astrocytic glioma 14 | 2,241
juvenile dermatomyositis 14 | 1,189
pancreatic ductal adenocarcinoma liver metastasis 14 | 1,795
Carcinoma 13 | 2,147
pediatric high grade glioma 13 | 2,712
sonic hedgehog group medulloblastoma 12 | 1,482
adult high grade glioma 11 | 2,148
group 4 medulloblastoma 11 | 1,875
Down syndrome 10 | 548
Mammary Neoplasms 10 | 410
invasive ductal carcinoma 10 | 2,950
Amyotrophic Lateral Sclerosis 9 | 431
Rheumatoid Arthritis 9 | 1,160
acute myeloid leukemia 9 | 780
lung carcinoma 9 | 2,844
medulloblastoma 9 | 1,524
pancreatic cancer 9 | 2,300
pilocytic astrocytoma 9 | 3,086
primary pancreatic ductal adenocarcinoma 8 | 1,271
progressive supranuclear palsy 8 | 674
tuberculosis and treatment for 6 months 8 | 686
ulcerative colitis 8 | 2,087
Alzheimer's disease 7 | 644
Intellectual disability 7 | 573
Neurodegenerative disease 7 | 383
atypical teratoid/rhabdoid tumor 7 | 1,095
colon cancer 7 | 1,475
cystic fibrosis 7 | 1,665
spina bifida 7 | 1,064
tuberculosis 7 | 1,557
IGA Glomerulonephritis 6 | 454
Stomach Neoplasms 6 | 282
adrenocortical carcinoma 6 | 1,427
breast carcinoma 6 | 1,614
mucosa-associated lymphoid tissue lymphoma 6 | 480
Mammary Neoplasms, Experimental 5 | 150
Vascular disease 5 | 281
autosomal dominant Emery-Dreifuss muscular dystrophy 5 | 499
gastric carcinoma 5 | 832
non primary Sjogren syndrome sicca 5 | 840
Animal Mammary Neoplasms 4 | 136
Degenerative polyarthritis 4 | 93
Diamond-Blackfan anemia 4 | 28
Disease Progression 4 | 125
Kidney disease 4 | 396
Lupus erythematosus 4 | 80
Multiple Sclerosis 4 | 498
Parkinson's disease 4 | 364
Peripheral Neuropathy 4 | 303
ductal carcinoma in situ 4 | 1,745
inflammatory breast cancer 4 | 404
nasopharyngeal carcinoma 4 | 1,056
pituitary cancer 4 | 1,972
posterior fossa group A ependymoma 4 | 1,511
posterior fossa group B ependymoma 4 | 1,530
primary Sjogren syndrome 4 | 789
relapsing-remitting multiple sclerosis 4 | 18
Craniofacial Abnormalities 3 | 147
Duchenne muscular dystrophy 3 | 602
Liver carcinoma 3 | 217
Lung Neoplasms 3 | 171
Muscular atrophy 3 | 67
Myocardial Ischemia 3 | 169
Prostate cancer 3 | 172
Prostatic Neoplasms 3 | 471
Rheumatic disease 3 | 9
Sjogren's syndrome 3 | 23
active Crohn's disease 3 | 918
aldosterone-producing adenoma 3 | 664
cutaneous lupus erythematosus 3 | 1,056
glioblastoma multiforme 3 | 347
hepatocellular carcinoma 3 | 532
hereditary spastic paraplegia 3 | 313

Tissue

Blood and immune system 112 | 17,995
Cardiovascular System 112 | 17,958
Digestive Tract 112 | 18,473
Endocrine System 112 | 18,512
Female tissues 112 | 18,647
Liver and Pancreas 112 | 18,136
Male tissues 112 | 17,969
Nervous System 112 | 18,561
Urinary Tract 112 | 18,444
Respiratory system 111 | 17,484
Skin and soft tissues 111 | 18,115

Target Family

Non-IDG 89 | 11,971
Enzyme 15 | 4,146
Kinase 6 | 634
Transcription Factor 3 | 1,400
Epigenetic 1 | 242

GO Component

intracellular ribonucleoprotei... 114 | 114
nucleus 5,107 | 5,107
cytoplasm 4,985 | 4,985
plasma membrane 4,118 | 4,118
integral component of membrane 3,679 | 3,679
cytosol 3,265 | 3,265
extracellular exosome 2,758 | 2,758
nucleoplasm 2,717 | 2,717
membrane 1,906 | 1,906
extracellular region 1,493 | 1,493
integral component of plasma m... 1,406 | 1,406
extracellular space 1,304 | 1,304
mitochondrion 1,231 | 1,231
Golgi apparatus 864 | 864
endoplasmic reticulum 859 | 859
endoplasmic reticulum membrane 848 | 848
nucleolus 815 | 815
Golgi membrane 659 | 659
perinuclear region of cytoplas... 611 | 611
cell surface 594 | 594
intracellular 548 | 548
intracellular membrane-bounded... 537 | 537
cell junction 451 | 451
mitochondrial inner membrane 425 | 425
centrosome 409 | 409
focal adhesion 383 | 383
protein complex 355 | 355
cytoskeleton 343 | 343
dendrite 329 | 329
mitochondrial matrix 322 | 322
cell-cell adherens junction 307 | 307
neuronal cell body 303 | 303
microtubule 294 | 294
lysosomal membrane 278 | 278
apical plasma membrane 277 | 277
proteinaceous extracellular ma... 244 | 244
neuron projection 229 | 229
nuclear membrane 218 | 218
early endosome 217 | 217
axon 214 | 214
lysosome 210 | 210
endosome 208 | 208
actin cytoskeleton 205 | 205
external side of plasma membra... 205 | 205
postsynaptic membrane 204 | 204
extracellular matrix 198 | 198
nuclear speck 197 | 197
membrane raft 196 | 196
endoplasmic reticulum lumen 192 | 192
transcription factor complex 184 | 184
endosome membrane 182 | 182
early endosome membrane 180 | 180
basolateral plasma membrane 174 | 174
nuclear chromatin 169 | 169
synapse 166 | 166
cell-cell junction 161 | 161
nuclear envelope 156 | 156
lamellipodium 153 | 153
mitochondrial outer membrane 148 | 148
blood microparticle 147 | 147
myelin sheath 144 | 144
postsynaptic density 144 | 144
cytoplasmic vesicle 143 | 143
microtubule organizing center 137 | 137
cytoplasmic, membrane-bounded ... 132 | 132
ER to Golgi transport vesicle ... 131 | 131
microtubule cytoskeleton 127 | 127
receptor complex 127 | 127
phagocytic vesicle membrane 126 | 126
cytoplasmic vesicle membrane 125 | 125
midbody 125 | 125
trans-Golgi network 124 | 124
cell cortex 119 | 119
cilium 118 | 118
late endosome 116 | 116
spindle 116 | 116
vesicle 112 | 112
Z disc 110 | 110
bicellular tight junction 110 | 110
anchored component of membrane 109 | 109
growth cone 109 | 109
integral component of lumenal ... 108 | 108
late endosome membrane 107 | 107
endomembrane system 106 | 106
centriole 105 | 105
recycling endosome 104 | 104
spindle pole 104 | 104
perikaryon 103 | 103
integral component of endoplas... 101 | 101
intermediate filament 101 | 101
melanosome 101 | 101
chromosome 100 | 100
dendritic spine 99 | 99
ubiquitin ligase complex 99 | 99
peroxisome 98 | 98
nuclear matrix 97 | 97
PML body 94 | 94
Golgi lumen 93 | 93
keratin filament 93 | 93
trans-Golgi network membrane 92 | 92

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
mRNA decay activator protein ZFP36 ZFP36 Tbio Non-IDG -2.38153 220.3 0
Interleukin enhancer-binding factor 2 ILF2 Tbio Non-IDG -1.51960 36.4 249
Interleukin enhancer-binding factor 3 ILF3 Tbio Non-IDG -2.09543 135.8 239
Glycogen synthase kinase-3 beta GSK3B Tclin Kinase -2.94349 567.7 767
40S ribosomal protein S3 RPS3 Tbio Non-IDG -2.16121 152.6 207
Transcriptional regulator ERG ERG Tchem Transcription Factor -2.49936 317.4 284
DNA-binding protein SMUBP-2 IGHMBP2 Tbio Non-IDG -1.84895 75.2 35
Protein CASC3 CASC3 Tbio Non-IDG -2.18418 180.2 207
Casein kinase I isoform epsilon CSNK1E Tchem Kinase -1.76876 60.7 272
Elongation factor 2 EEF2 Tchem Non-IDG -2.93803 911.5 347